Prospective unmasked randomized evaluation of the iStent inject® versus two ocular hypotensive agents in patients with primary open-angle glaucoma

Clinical Ophthalmology

Volumn 8, Issue , 2014, Pages 875-882

  Fea, Antonio M ^a   Belda, Jose I ^b   Rekas, Marek ^c   Jünemann, Anselm ^d   Chang, Lydia ^e   Pablo, Luis ^f   Voskanyan, Lilit ^g   Katz, L Jay ^h  

^a UNIVERSITY OF TURIN   (Italy)

^b Hospital de Torrevieja Salud   (Spain)

^c MILITARY INSTITUTE OF MEDICINE   (Poland)

^d UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^e HINCHINGBROOKE HOSPITAL   (United Kingdom)

^f HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

^g SV Malayan Ophthalmologic Center   (Armenia)

^h THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Ab interno; Intraocular pressure; IOP reduction; OAG; Trabecular bypass

Indexed keywords

LATANOPROST PLUS TIMOLOL;

ADULT; AGED; ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CUP TO DISC RATIO; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG TOLERABILITY; EYE BURNING; EYE DISCOMFORT; FEMALE; HUMAN; INTERMETHOD COMPARISON; INTRAOCULAR PRESSURE; INTRAOCULAR PRESSURE ABNORMALITY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OPEN ANGLE GLAUCOMA; OPHTHALMOLOGICAL PROSTHESIS AND IMPLANT; OUTCOME ASSESSMENT; PATIENT SAFETY; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRESSURE MEASUREMENT; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SURGICAL APPROACH; TRABECULAR MICRO BYPASS DEVICE; TREATMENT RESPONSE; VERY ELDERLY; VISUAL ACUITY; VISUAL SYSTEM PARAMETERS;

EID: 84900411462     PISSN: 11775467     EISSN: 11775483     Source Type: Journal    
DOI: 10.2147/OPTH.S59932     Document Type: Article

References (21)

1. Liesegang TJ. Conjunctival changes associated with glaucoma therapy: implications for the external disease consultant and the treatment of glaucoma. Cornea. 1998;17(6):574-583.
2. Spiegel D, Garcia-Feijoo J, Garcia-Sanchez J, Lamielle H. Coexistent primary open-angle glaucoma and cataract: preliminary analysis of treatment by cataract surgery and the iStent trabecular micro-bypass stent. Adv Ther. 2008;25(5):453-464.
3. Samuelson TW, Katz LJ, Wells JM, Duh YJ, Giamporcaro JE; US iStent Study Group. Randomized evaluation of the trabecular micro-bypass stent with phacoemulsification in patients with glaucoma and cataract. Ophthalmology. 2011;118(3):459-467.
4. Craven ER, Katz LJ, Wells JM, Giamporcaro JE; iStent Study Group. Cataract surgery with trabecular micro-bypass stent implantation in patients with mild-to-moderate open-angle glaucoma and cataract: 2-year follow-up. J Cataract Refract Surg. 2012;38(8):1339-1345.
5. Fea AM. Phacoemulsification versus phacoemulsification with micro-bypass stent implantation in primary open-angle glaucoma: randomized double-masked clinical trial. J Cataract Refract Surg. 2010;36(3): 407-412.
6. Fea AM, Pignata G, Bartoli E, et al. Prospective, randomized, double-masked trial of trabecular bypass stent and cataract surgery vs cataract surgery alone in primary OAG: long-term data. In: Program and abstracts of the XXX Congress of the European Society of Cataract and Refractive Surgeons; September 8-12, 2012; Milan, Italy.
7. Arriola-Villalobos P, Martinez-de-la-Casa J, Diaz-Valle D, Fernandez-Perez C, Garcia-Sanchez J, Garcia-Feijoo J. Combined iStent trabecular micro-bypass stent implantation and phacoemulsification for coexistent open-angle glaucoma and cataract: a long-term study. Br J Ophthalmol. 2012;96(5):645-649.
8. Spiegel D, Wetzel W, Neuhann T, et al. Coexistent primary open-angle glaucoma and cataract: interim analysis of a trabecular micro-bypass stent and concurrent cataract surgery. Eur J Ophthalmol. 2009;19(3):393-399.
9. Bahler CK, Smedley GT, Zhou J, Johnson DH. Trabecular bypass stents decrease intraocular pressure in cultured human anterior segments. Am J Ophthalmol. 2004;138(6):988-994.
10. Belovay GW, Naqi A, Chan BJ, Rateb M, Ahmed II. Using multiple trabecular micro-bypass stents in cataract patients to treat open-angle glaucoma. J Cataract Refract Surg. 2012;38(11):1911-1917.
11. Bahler CK, Hann CR, Fjield T, Haffner D, Heitzmann H, Fautsch MP. Second-generation trabecular meshwork bypass stent (iStent inject) increases outflow facility in cultured human anterior segments. Am J Ophthalmol. 2012;153(6):1206-1213.
12. Ammar DA, Kahook MY. Effects of benzalkonium chloride-or polyquad-preserved fixed combination glaucoma medications on human trabecular meshwork cells. Mol Vis. 2011;17:1806-1813.
13. Nagai N, Murao T, Oe K, Ito Y, Okamoto N, Shimomura Y. [In vitro evaluation for corneal damages by anti-glaucoma combination eye drops using human corneal epithelial cell (HCE-T)]. Yakugaku Zasshhi. 2011;131(6):985-991. Japanese [with English abstract].
14. Brignole-Baudouin F, Riancho L, Liang H, Nakib Z, Baudouin C. In vitro comparative toxicology of polyquad-preserved and benzalkonium chloride-preserved travoprost/timolol fixed combination and latanoprost/timolol fixed combination. J Ocul Pharmacol Ther. 2011;27(3):273-280.
15. Alm A, Gunden JW, Kwok KK. Five-year, multicenter safety study of fixed combination latanoprost/timolol (Xalacom) for open-angle glaucoma and ocular hypertension. J Glaucoma. 2011;20(4):215-222.
16. Chang DF. Intraocular pressure reduction and safety outcomes following micro-invasive glaucoma surgery with two trabecular micro-bypass stents in OAG. In: Program and abstracts of the XXXI Congress of the European Society of Cataract and Refractive Surgeons; October 5-9, 2013; Amsterdam, the Netherlands.
17. Garcia-Feijoo J, Martinez de la Casa J. Micro-invasive glaucoma surgery (MIGS) with trabecular micro-bypass stents and postoperative prostaglandin in open-angle glaucoma subjects. In: Program and abstracts of the XXXI Congress of the European Society of Cataract and Refractive Surgeons; October 5-9, 2013; Amsterdam, the Netherlands.
18. Heijl A, Traverso CE, editors. Terminology and Guidelines for Glaucoma. 3rd ed. Leuven: European Glaucoma Society; 2008.
19. Bucolo C, Salomone S, Drago F, Reibaldi M, Longo A, Uva MG. Pharmacological management of ocular hypertension: current approaches and future prospective. Curr Opin Pharmacol. 2013;13(1): 50-55.
20. Johnstone M, Martin E, Jamil A. Pulsatile flow into the aqueous veins: manifestations in normal and glaucomatous eyes. Exp Eye Res. 2011;92(5):318-327.
21. Ren J, Gille HK, Wu J, Yang C. Ex vivo optical coherence tomography imaging of collector channels with a scanning endoscopic probe. Invest Ophthalmol Vis Sci. 2011;52(7):3921-3925.