The metabolic inter-relationships between changes in waist circumference, triglycerides, insulin sensitivity and small, dense low-density lipoprotein particles with acute weight loss in clinically obese children and adolescents

Pediatric Obesity

Volumn 9, Issue 3, 2014, Pages 209-217

  Hobkirk, J P ^a   King, R F ^b   Davies, I ^e   Harman, N ^f   Gately, P ^b   Pemberton, P ^c   Smith, A ^c   Barth, J H ^d   Carroll, S ^g  

^a UNIVERSITY OF HULL   (United Kingdom)

^b LEEDS METROPOLITAN UNIVERSITY   (United Kingdom)

^c MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^d LEEDS GENERAL INFIRMARY   (United Kingdom)

^e LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^f UNIVERSITY OF LIVERPOOL   (United Kingdom)

^g UNIVERSITY OF HULL   (United Kingdom)

Author keywords

dense LDL; Insulin sensitivity; small; triglyceride; weight loss

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; LOW DENSITY LIPOPROTEIN;

ADOLESCENT; ARTICLE; BODY COMPOSITION; BODY MASS; CARDIOMETABOLIC RISK; CHILD; CHILDHOOD OBESITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DENSITY; FAT MASS; FEMALE; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LOW DENSITY LIPOPROTEIN CHOLESTEROL PATTERN B; LOW DENSITY LIPOPROTEIN CHOLESTEROL PEAK PARTICLE DENSITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE; WEIGHT REDUCTION; CALORIC RESTRICTION; DYSLIPIDEMIAS; HEALTH EDUCATION; METABOLISM; PEDIATRIC OBESITY; PILOT STUDY;

ADOLESCENT; BODY MASS INDEX; CALORIC RESTRICTION; CHILD; DYSLIPIDEMIAS; FEMALE; HEALTH EDUCATION; HUMANS; INSULIN RESISTANCE; LIPOPROTEINS, LDL; MALE; PEDIATRIC OBESITY; PILOT PROJECTS; TRIGLYCERIDES; WAIST CIRCUMFERENCE; WEIGHT LOSS;

EID: 84900386326     PISSN: 20476302     EISSN: 20476310     Source Type: Journal    
DOI: 10.1111/j.2047-6310.2013.00165.x     Document Type: Article

References (31)

1. Wang Y, Lobstein T,. Worldwide trends in childhood overweight and obesity. Int J Pediatr Obes 2006; 1: 11-25.
2. Morrison JA, Friedman LA, Wang P, Glueck CJ,. Metabolic syndrome in childhood predicts adult metabolic syndrome and type 2 diabetes mellitus 25 to 30 years later. J Pediatr 2008; 152: 201-206.
3. Steinberger J, Moorehead C, Katch V, Rocchini AP,. Relationship between insulin resistance and abnormal lipid profile in obese adolescents. J Pediatr 1995; 126: 690-695.
4. Albers JJ, Marcovina SM, Imperatore G, et al. Prevalence and determinants of elevated apolipoprotein B and dense low-density lipoprotein in youths with type 1 and type 2 diabetes. J Clin Endocrinol Metab 2008; 93: 735-742.
5. Magnussen CG, Raitakari OT, Thomson R, et al. Utility of currently recommended pediatric dyslipidemia classifications in predicting dyslipidemia in adulthood: evidence from the Childhood Determinants of Adult Health (CDAH) study, Cardiovascular Risk in Young Finns Study, and Bogalusa Heart Study. Circulation 2008; 117: 32-42.
6. Epstein LH, Kuller LH, Wing RR, Valoski A, McCurley J,. The effect of weight control on lipid changes in obese children. Am J Dis Child 1989; 143: 454-457.
7. Huelsing J, Kanafani N, Mao J, White NH,. Camp jump start: effects of a residential summer weight-loss camp for older children and adolescents. Pediatrics 2010; 125: e884-e890.
8. Kolsgaard ML, Joner G, Brunborg C, Anderssen SA, Tonstad S, Andersen LF,. Reduction in BMI z-score and improvement in cardiometabolic risk factors in obese children and adolescents. The Oslo Adiposity Intervention Study-a hospital/public health nurse combined treatment. BMC Pediatr 2011; 11: 47.
9. Monzavi R, Dreimane D, Geffner ME, et al. Improvement in risk factors for metabolic syndrome and insulin resistance in overweight youth who are treated with lifestyle intervention. Pediatrics 2006; 117: e1111-e1118.
10. Reinehr T, Kleber M, Toschke AM,. Lifestyle intervention in obese children is associated with a decrease of the metabolic syndrome prevalence. Atherosclerosis 2009; 207: 174-180.
11. Savoye M, Shaw M, Dziura J, et al. Effects of a weight management program on body composition and metabolic parameters in overweight children: a randomized controlled trial. JAMA 2007; 297: 2697-2704.
12. Shalitin S, Ashkenazi-Hoffnung L, Yackobovitch-Gavan M, et al. Effects of a twelve-week randomized intervention of exercise and/or diet on weight loss and weight maintenance, and other metabolic parameters in obese preadolescent children. Horm Res 2009; 72: 287-301.
13. King RF, Hobkirk JP, Cooke CB, Radley D, Gately PJ,. Low-density lipoprotein sub-fraction profiles in obese children before and after attending a residential weight loss intervention. J Atheroscler Thromb 2008; 15: 100-107.
14. Ferguson MA, Gutin B, Le NA, et al. Effects of exercise training and its cessation on components of the insulin resistance syndrome in obese children. Int J Obes Relat Metab Disord 1999; 23: 889-895.
15. Kang HS, Gutin B, Barbeau P, et al. Physical training improves insulin resistance syndrome markers in obese adolescents. Med Sci Sports Exerc 2002; 34: 1920-1927.
16. Gately PJ, Cooke CB, Barth JH, Bewick BM, Radley D, Hill AJ,. Children's residential weight-loss programs can work: a prospective cohort study of short-term outcomes for overweight and obese children. Pediatrics 2005; 116: 73-77.
17. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH,. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000; 320: 1240-1243.
18. Schofield WN,. Predicting basal metabolic rate, new standards and review of previous work. Hum Nutr Clin Nutr 1985; 39 (Suppl 1): 5-41.
19. Jebb SA, Cole TJ, Doman D, Murgatroyd PR, Prentice AM,. Evaluation of the novel Tanita body-fat analyser to measure body composition by comparison with a four-compartment model. Br J Nutr 2000; 83: 115-122.
20. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC,. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
21. Davies IG, Graham JM, Griffin BA,. Rapid separation of LDL subclasses by iodixanol gradient ultracentrifugation. Clin Chem 2003; 49: 1865-1872.
22. Zambon A, Hokanson JE, Brown BG, Brunzell JD,. Evidence for a new pathophysiological mechanism for coronary artery disease regression: hepatic lipase-mediated changes in LDL density. Circulation 1999; 99: 1959-1964.
23. Lamarche B, Tchernof A, Moorjani S, et al. Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the Quebec Cardiovascular Study. Circulation 1997; 95: 69-75.
24. Willi SM, Hirst K, Jago R, et al. Cardiovascular risk factors in multi-ethnic middle school students: the HEALTHY primary prevention trial. Pediatr Obes 2012; 7: 230-239.
25. Kang HS, Gutin B, Barbeau P, Litaker MS, Allison J, Le NA,. Low-density lipoprotein particle size, central obesity, cardiovascular fitness, and insulin resistance syndrome markers in obese youths. Int J Obes Relat Metab Disord 2002; 26: 1030-1035.
26. Miyashita M, Okada T, Kuromori Y, Harada K,. LDL particle size, fat distribution and insulin resistance in obese children. Eur J Clin Nutr 2006; 60: 416-420.
27. Bioletto S, Golay A, Munger R, Kalix B, James RW,. Acute hyperinsulinemia and very-low-density and low-density lipoprotein subfractions in obese subjects. Am J Clin Nutr 2000; 71: 443-449.
28. Pinhas-Hamiel O, Lerner-Geva L, Copperman NM, Jacobson MS,. Lipid and insulin levels in obese children: changes with age and puberty. Obesity (Silver Spring) 2007; 15: 2825-2831.
29. Reinehr T, Toschke AM,. Onset of puberty and cardiovascular risk factors in untreated obese children and adolescents: a 1-year follow-up study. Arch Pediatr Adolesc Med 2009; 163: 709-715.
30. Conwell LS, Trost SG, Brown WJ, Batch JA,. Indexes of insulin resistance and secretion in obese children and adolescents: a validation study. Diabetes Care 2004; 27: 314-319.
31. Davis JN, Ventura EE, Tung A, et al. Effects of a randomized maintenance intervention on adiposity and metabolic risk factors in overweight minority adolescents. Pediatr Obes 2012; 7: 16-27.