Characterization of cytomegalovirus lung infection in non-HIV infected children

Viruses

Volumn 6, Issue 5, 2014, Pages 2038-2051

  Restrepo Gualteros, Sonia M ^a,b   Jaramillo Barberi, Lina E ^a,c   Gonzalez Santos, Monica ^c   Rodriguez Martinez, Carlos E ^c,d,e   Perez, Geovanny F ^f   Gutierrez, Maria J ^g   Nino, Gustavo ^f,h  

^a Division of Pediatric Pulmonology Fundacion Hospital La Misericordia   (Colombia)

^b School of Medicine   (Colombia)

^c UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^d UNIVERSIDAD EL BOSQUE   (Colombia)

^e HOSPITAL MILITAR CENTRAL   (Colombia)

^f CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^g PENN STATE COLLEGE OF MEDICINE   (United States)

^h GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Children; CMV; Ground glass; Lung; Pneumonia

Indexed keywords

GANCICLOVIR; IMMUNOGLOBULIN M; VALGANCICLOVIR;

ABNORMAL RESPIRATORY SOUND; ADOLESCENT; ARTICLE; BREATHING DISORDER; BRONCHOSCOPY; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; COUGHING; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; HYPOXEMIA; IMMUNOHISTOCHEMISTRY; INFANT; LUNG BIOPSY; LUNG INFECTION; LUNG LAVAGE; MALE; MEDICAL RECORD REVIEW; MORTALITY; NONHUMAN; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; RADIOLOGICAL PARAMETERS; RESPIRATORY FAILURE; SEROLOGY; THORAX RADIOGRAPHY; VIRUS CHARACTERIZATION; VIRUS LOAD; CYTOMEGALOVIRUS INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ISOLATION AND PURIFICATION; LUNG; MICROBIOLOGY; NEWBORN; PATHOLOGY; PNEUMONIA, VIRAL; RADIOGRAPHY; RESPIRATORY INSUFFICIENCY; SURVIVAL; VIROLOGY;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; HIV INFECTIONS; HUMANS; INFANT; INFANT, NEWBORN; LUNG; MALE; PNEUMONIA, VIRAL; RESPIRATORY INSUFFICIENCY; SURVIVAL ANALYSIS;

EID: 84900385622     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v6052038     Document Type: Article

References (27)

1. Manicklal, S.; Emery, V.C.; Lazzarotto, T.; Boppana, S.B.; Gupta, R.K. The "silent" global burden of congenital citomegalovirus. Clin. Microbiol. Rev. 2013, 26, 86-102.
2. Russel, M.; Palmer, A.; Michaels, M. Citomegalovirus infection in pediatric inmunocompromised hosts. Infect. Disord. Drug Targets 2011, 11, 437-448.
3. Gandhi, M.; Khanna, R. Human cytomegalovirus: Clinical aspects, immune regulation, and emerging treatments. Lancet Infect. Dis. 2004, 4, 725-738.
4. Radigan, K.; Wunderink, R. Epidemic viral pneumonia and other emerging pathogens. Clin. Chest Med. 2011, 32, 451-467.
5. Smith, S.D.; Cho, C.T.; Brahmacupta, N.; Lenahan, M.F. Pulmonary involvement with cytomegalovirus infections in children. Arch. Dis. Child. 1977, 52, 441-446.
6. Zhou, W.; Lin, F.; Teng, L.; Li, H.; Hou, J.; Tong, R.; Zheng, C.; Lou, Y.; Tan, W. Prevalence of herpes and respiratory viruses in induced sputum among hospitalized children with non typical bacterial community-acquired pneumonia. PLoS One 2013, 8, e79477.
7. Jouneau, S.; Poineuf, J.S.; Minjolle, S.; Tattevin, P.; Uhel, F.; Kerjouan, M.; le Hô, H.; Desrues, B. Wich patients should be tested for viruses on bronchoalveolar lavage fluid? Eur. J. Clin. Microbiol. Infect. Dis. 2013, 32, 671-677.
8. Cunha, B.A. Cytomegalovirus pneumonia: Community-acquired pneumonia in immunocompetent hosts. Infect. Dis. Clin. North Am. 2010, 24, 147-158.
9. De Blic, J.; Midulla, F.; Barbato, A.; Clement, A.; Dab, I.; Eber, E.; Green, C.; Grigg, J.; Kotecha, S.; Kurland, G.; et al. Bronchoalveolar lavage in children. ERS Task Force on bronchoalveolar lavage in children. European Respiratory Society. Eur. Respir. J. 2000, 15, 217-231.
10. Hansel, D.M.; Bankier, A.A.; MacMahon, H.; McLoud, T.C.; Müller, N.L.; Remy, J. Fleischner society: Glossary of terms for thoracic imaging. Radiology 2008, 246, 697-722.
11. Doan, T.; Phung, T.T.; Pham, H.V.; Pham, S.H.; Nguyen, L.T. Effect of ganciclovir for the treatment of severe cytomegalovirus-associated pneumonia in children without a specific immunocompromised state. BMC Infect. Dis. 2013, 13, e424.
12. Jogeesvaran, K.H.; Owens, C. Chronic diseases of lung parenchyma in children: The role of imaging. Pediatr. Radiol. 2010, 40, 850-858.
13. Alarcon, A.A.; Baquero-Artigao, F.; Grupo de estudio de la infección por citomegalovirus de la Sociedad Española de Infectología Pediátrica. Review and guidelines on the prevention, diagnosis and treatment of post-natal cytomegalovirus infection. An. Pediatr. 2011, 74, doi:10.1016/j.anpedi.2010.05.024.
14. Escribano, A.; Chilet, M.; Clari, M. Á.; Lucas, R.; Costa, E.; Bravo, D.; Muñoz-Cobo, B.; Borrás, R.; Navarro, D. Frequent detection of cytomegalovirus (CMV) DNA in the lower respiratory tract in CMV-seropositive pediatric patients with underlying chronic bronchopulmonary diseases lacking canonical immunosuppression. J. Med. Virol. 2013, 85, 888-892.
15. Khan, N. The immunological burden of human cytomegalovirus infection. Arch. Immunol. Ther. Exp. 2007, 55, 299-308.
16. Lidehäll, A.K.; Engman, M.L.; Sund, F.; Malm, G.; Lewensohn-Fuchs, I.; Ewald, U.; Tötterman, T.H.; Karltorp, E.; Korsgren, O.; Eriksson, B.M. Cytomegalovirus-specific CD4 and CD8 T cell responses in infants and children. Scand. J. Immunol. 2013, 77, 135-143.
17. La Rosa, C.; Diamond, D.J. The immune response to human CMV. Future Virol. 2012, 7, 279-293.
18. Corrin, B.; Nicholson, A.G. Pathology of the Lungs, 2nd ed.; Elsevier: London, UK, 2006; Chapter 5, pp. 159-160.
19. Griffiths, M.H.; Miller, R.F.; Semple, S.J. Interstitial pneumonitis in patients infected with the human immunodeficiency virus. Thorax 1995, 50, 1141-1146.
20. Jeena, P.M.; Coovadia, H.M.; Chrystal, V. Pneumocystis carinii and cytomegalovirus infections in severely ill, HIV-infected African infants. Ann. Trop. Paediatr. 1996, 16, 361-368.
21. Avila-Agüero, M.L.; Paris, M.M.; Alfaro, W.; Avila-Agüero, C.R.; Faingezicht, I. Ganciclovir therapy in cytomegalovirus (CMV) infection in immunocompetent pediatric patients. Int. J. Infect. Dis. 2003, 7, 278-281.
22. Honda, J.; Yonemitsu, J.; Kitajima, H.; Yosida, N.; Fumirori, T.; Oizumi, K. Clinical utility of capillary polymerase chain reaction for diagnosis of Cyto-megalovirus pneumonia. Scand. J. Infect. Dis. 2001, 33, 702-705.
23. Ljungman, P. Cytomegalovirus pneumonia: Presentation, diagnosis, and treatment. Semin. Respir. Infect. 1995, 10, 209-215.
24. Moon, J.H.; Kim, E.A.; Lee, K.S.; Kim, T.S.; Jung, K.J.; Song, J.H. Cytomegalovirus pneumonia: High-resolution CT findings in ten non-AIDS immunocompromised patients. Korean J. Radiol. 2000, 1, 73-78.
25. West, B.W. Respiratory Physiology the Essentials: Ventilation-Perfusion Relationships, 9th ed.; Lippincott Williams & Wilkins: Baltimore, MD, USA, 2012; pp. 56-76.
26. Agrawal, A.; Agrawal, A.; Bansal, V.; Pandit, M. A systematic approach to interpretation of heterogeneous lung attenuation on computed tomography of the chest. Lung India 2013, 30, 327-334.
27. Popler, J.; Gower, W.A.; Mogayzel, P.J., Jr.; Nogee, L.M.; Langston, C.; Wilson, A.C.; Hay, T.C.; Deterding, R.R. Familial neuroendocrine cell hyperplasia of infancy. Pediatr. Pulmonol. 2010, 45, 749-755.