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Volumn 2, Issue , 2010, Pages 139-160

Biosynthesis and regulation of alkaloids

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EID: 84900200099     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-04670-4_8     Document Type: Chapter
Times cited : (33)

References (88)
  • 1
    • 26844450886 scopus 로고    scopus 로고
    • Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment
    • Alcantara J, Bird DA, Franceschi VR, Facchini PJ (2005) Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment. Plant Physiol 138:173-183
    • (2005) Plant Physiol , vol.138 , pp. 173-183
    • Alcantara, J.1    Bird, D.A.2    Franceschi, V.R.3    Facchini, P.J.4
  • 3
    • 33646031512 scopus 로고    scopus 로고
    • Caffeine biosynthesis and adenine metabolism in transgenic Coffea canephora plants with reduced expression of N-methyltransferase genes
    • Ashihara H, Zheng XQ, Katahira R, Morimoto M, Ogita S, Sano H (2006) Caffeine biosynthesis and adenine metabolism in transgenic Coffea canephora plants with reduced expression of N-methyltransferase genes. Phytochemistry 67:882-886
    • (2006) Phytochemistry , vol.67 , pp. 882-886
    • Ashihara, H.1    Zheng, X.Q.2    Katahira, R.3    Morimoto, M.4    Ogita, S.5    Sano, H.6
  • 4
    • 39149121177 scopus 로고    scopus 로고
    • Caffeine and related purine alkaloids: Biosynthesis, catabolism, function and genetic engineering
    • Ashihara H, Sano H, Crozier A (2008) Caffeine and related purine alkaloids: biosynthesis, catabolism, function and genetic engineering. Phytochemistry 69:841-856
    • (2008) Phytochemistry , vol.69 , pp. 841-856
    • Ashihara, H.1    Sano, H.2    Crozier, A.3
  • 5
    • 35748962318 scopus 로고    scopus 로고
    • Molecular architecture of strictosidine glucosidase: The gateway to the biosynthesis of the monoterpenoid indole alkaloid family
    • Barleben L, Panjikar S, Ruppert M, Koepke J, Stöckigt J (2007) Molecular architecture of strictosidine glucosidase: the gateway to the biosynthesis of the monoterpenoid indole alkaloid family. Plant Cell 19:2886-2897
    • (2007) Plant Cell , vol.19 , pp. 2886-2897
    • Barleben, L.1    Panjikar, S.2    Ruppert, M.3    Koepke, J.4    Stöckigt, J.5
  • 6
    • 34547927914 scopus 로고    scopus 로고
    • Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle
    • Bernhardt P, McCoy E, O'Connor SE (2007) Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle. Chem Biol 14:888-897
    • (2007) Chem Biol , vol.14 , pp. 888-897
    • Bernhardt, P.1    McCoy, E.2    O'Connor, S.E.3
  • 7
    • 0034778031 scopus 로고    scopus 로고
    • Berberine bridge enzyme, a key branch-point enzyme in benzylisoquinoline alkaloid biosynthesis, contains a vacuolar sorting determinant
    • Bird DA, Facchini PJ (2001) Berberine bridge enzyme, a key branch-point enzyme in benzylisoquinoline alkaloid biosynthesis, contains a vacuolar sorting determinant. Planta 213:888-897
    • (2001) Planta , vol.213 , pp. 888-897
    • Bird, D.A.1    Facchini, P.J.2
  • 8
    • 0345376982 scopus 로고    scopus 로고
    • A tale of three cell types: Alkaloid biosynthesis is localized to sieve elements in opium poppy
    • Bird DA, Franceschi VR, Facchini P (2003) A tale of three cell types: alkaloid biosynthesis is localized to sieve elements in opium poppy. Plant Cell 15:2626-2635
    • (2003) Plant Cell , vol.15 , pp. 2626-2635
    • Bird, D.A.1    Franceschi, V.R.2    Facchini, P.3
  • 9
    • 0036834176 scopus 로고    scopus 로고
    • Immunocytological localization of two enzymes involved in berberine biosynthesis
    • Bock A, Wanner G, Zenk MH (2002) Immunocytological localization of two enzymes involved in berberine biosynthesis. Planta 216:57-63
    • (2002) Planta , vol.216 , pp. 57-63
    • Bock, A.1    Wanner, G.2    Zenk, M.H.3
  • 10
    • 1842430598 scopus 로고    scopus 로고
    • Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids and isoprenoid-derived primary metabolites
    • Burlat V, Oudin A, Courtois M, Rideau M, St-Pierre B (2004) Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids and isoprenoid-derived primary metabolites. Plant J 38:131-141
    • (2004) Plant J , vol.38 , pp. 131-141
    • Burlat, V.1    Oudin, A.2    Courtois, M.3    Rideau, M.4    St-Pierre, B.5
  • 11
    • 0032127941 scopus 로고    scopus 로고
    • Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus
    • Canel C, Lopes-Cardoso I, Whitmer S, van der Fits L, Pasquali G, van der Heijden R, Hoge JHC, Verpoorte R (1998) Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus. Planta 205:414-419
    • (1998) Planta , vol.205 , pp. 414-419
    • Canel, C.1    Lopes-Cardoso, I.2    Whitmer, S.3    Van Der Fits, L.4    Pasquali, G.5    Van Der Heijden, R.6    Hoge, J.H.C.7    Verpoorte, R.8
  • 13
    • 33751009100 scopus 로고    scopus 로고
    • Redesign of a central enzyme in alkaloid biosynthesis
    • Chen S, Galan MC, Coltharp C, O'Connor SE (2006) Redesign of a central enzyme in alkaloid biosynthesis. Chem Biol 13:1137-1141
    • (2006) Chem Biol , vol.13 , pp. 1137-1141
    • Chen, S.1    Galan, M.C.2    Coltharp, C.3    O'Connor, S.E.4
  • 15
    • 38949166148 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a vacuolar class III peroxidase involved in the metabolism of anticancer alkaloids in Catharanthus roseus
    • Costa MM, Hilliou F, Duarte P, Pereira LG, Almeida I, Leech M, Memelink J, Barceló AR, Sottomayor M (2008) Molecular cloning and characterization of a vacuolar class III peroxidase involved in the metabolism of anticancer alkaloids in Catharanthus roseus. Plant Physiol 146:403-417
    • (2008) Plant Physiol , vol.146 , pp. 403-417
    • Costa, M.M.1    Hilliou, F.2    Duarte, P.3    Pereira, L.G.4    Almeida, I.5    Leech, M.6    Memelink, J.7    Barceló, A.R.8    Sottomayor, M.9
  • 16
    • 0034177601 scopus 로고    scopus 로고
    • The cell and developmental biology of alkaloid biosynthesis
    • De Luca V, St-Pierre B (2000) The cell and developmental biology of alkaloid biosynthesis. Trends Plant Sci 5:168-173
    • (2000) Trends Plant Sci , vol.5 , pp. 168-173
    • De Luca, V.1    St-Pierre, B.2
  • 18
    • 0037195484 scopus 로고    scopus 로고
    • Analysis of tropane and related alkaloids
    • Dräger B (2002) Analysis of tropane and related alkaloids. J Chromatogr A 978:1-35
    • (2002) J Chromatogr A , vol.978 , pp. 1-35
    • Dräger, B.1
  • 19
    • 31344443596 scopus 로고    scopus 로고
    • Tropinone reductases, enzymes at the branch point of tropane alkaloid metabolism
    • Dräger B (2006) Tropinone reductases, enzymes at the branch point of tropane alkaloid metabolism. Phytochemistry 67:327-337
    • (2006) Phytochemistry , vol.67 , pp. 327-337
    • Dräger, B.1
  • 20
    • 26844465113 scopus 로고    scopus 로고
    • Synthesis and trafficking of alkaloid biosynthetic enzymes
    • Facchini PJ, St-Pierre B (2005) Synthesis and trafficking of alkaloid biosynthetic enzymes. Curr Opin Plant Biol 8:657-666
    • (2005) Curr Opin Plant Biol , vol.8 , pp. 657-666
    • Facchini, P.J.1    St-Pierre, B.2
  • 21
    • 0037310922 scopus 로고    scopus 로고
    • Selective desensitization of jasmonate and pH-dependent signaling in the induction of benzophenanthridine biosynthesis in cells of Eschscholzia californica
    • Färber K, Schumann B, Miersch O, Roos W (2003) Selective desensitization of jasmonate and pH-dependent signaling in the induction of benzophenanthridine biosynthesis in cells of Eschscholzia californica. Phytochemistry 62:491-500
    • (2003) Phytochemistry , vol.62 , pp. 491-500
    • Färber, K.1    Schumann, B.2    Miersch, O.3    Roos, W.4
  • 22
    • 33847279410 scopus 로고    scopus 로고
    • Metabolic engineering with a morphine biosynthetic P450 in opium poppy surpasses breeding
    • Frick S, Kramell R, Kutchan TM (2007) Metabolic engineering with a morphine biosynthetic P450 in opium poppy surpasses breeding. Metab Eng 9:169-176
    • (2007) Metab Eng , vol.9 , pp. 169-176
    • Frick, S.1    Kramell, R.2    Kutchan, T.M.3
  • 23
    • 0033492452 scopus 로고    scopus 로고
    • Alkaloid production by a Cinchona officinalis "Ledgeriana" hairy root culture containing constitutive expression constructs of tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus
    • Geerlings A, Hallard D, Caballero AM, Cardoso IL, van der Heijden R, Verpoorte R (1999) Alkaloid production by a Cinchona officinalis "Ledgeriana" hairy root culture containing constitutive expression constructs of tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus. Plant Cell Rep 19:191-196
    • (1999) Plant Cell Rep , vol.19 , pp. 191-196
    • Geerlings, A.1    Hallard, D.2    Caballero, A.M.3    Cardoso, I.L.4    Van Der Heijden, R.5    Verpoorte, R.6
  • 24
    • 34249804156 scopus 로고    scopus 로고
    • Molecular modeling and site-directed mutagenesis reveal the benzylisoquinoline binding site of the short-chain dehydrogenase/reductase salutaridine reductase
    • Geissler R, Brandt W, Ziegler J (2007) Molecular modeling and site-directed mutagenesis reveal the benzylisoquinoline binding site of the short-chain dehydrogenase/reductase salutaridine reductase. Plant Physiol 143:1493-1503
    • (2007) Plant Physiol , vol.143 , pp. 1493-1503
    • Geissler, R.1    Brandt, W.2    Ziegler, J.3
  • 25
    • 0346034533 scopus 로고    scopus 로고
    • Secretion of secondary metabolites by ATP-binding cassette transporters in plant cell suspension cultures
    • Goossens A, Häkkinen ST, Laakso I, Oksman-Caldentey KM, Inzé D (2003) Secretion of secondary metabolites by ATP-binding cassette transporters in plant cell suspension cultures. Plant Physiol 131:1161-1164
    • (2003) Plant Physiol , vol.131 , pp. 1161-1164
    • Goossens, A.1    Häkkinen, S.T.2    Laakso, I.3    Oksman-Caldentey, K.M.4    Inzé, D.5
  • 26
    • 69449106943 scopus 로고    scopus 로고
    • Optimization of the transient transformation of Catharanthus roseus cells by particle bombardment and its application to the subcellular localization of hydroxymethylbutenyl 4-diphosphate synthase and geraniol 10-hydroxylase
    • Guirimand G, Burlat V, Oudin A, Lanoue A, St-Pierre B, Courdavault V (2009) Optimization of the transient transformation of Catharanthus roseus cells by particle bombardment and its application to the subcellular localization of hydroxymethylbutenyl 4-diphosphate synthase and geraniol 10-hydroxylase. Plant Cell Rep 28:1215-1234
    • (2009) Plant Cell Rep , vol.28 , pp. 1215-1234
    • Guirimand, G.1    Burlat, V.2    Oudin, A.3    Lanoue, A.4    St-Pierre, B.5    Courdavault, V.6
  • 27
    • 48449084795 scopus 로고    scopus 로고
    • Plant metabolomics: Analytical platforms and integration with functional genomics
    • Hagel JM, Facchini PJ (2008) Plant metabolomics: analytical platforms and integration with functional genomics. Phytochem Rev 7:479-497
    • (2008) Phytochem Rev , vol.7 , pp. 479-497
    • Hagel, J.M.1    Facchini, P.J.2
  • 28
    • 53749090789 scopus 로고    scopus 로고
    • Quantitative 1H nuclear magnetic resonance metabolite profiling as a functional genomics platform to investigate alkaloid biosynthesis in opium poppy
    • Hagel JM, Weljie AM, Vogel HJ, Facchini PJ (2008) Quantitative 1H nuclear magnetic resonance metabolite profiling as a functional genomics platform to investigate alkaloid biosynthesis in opium poppy. Plant Physiol 147:1805-1821
    • (2008) Plant Physiol , vol.147 , pp. 1805-1821
    • Hagel, J.M.1    Weljie, A.M.2    Vogel, H.J.3    Facchini, P.J.4
  • 29
    • 0025782677 scopus 로고
    • Hyoscyamine 6β-hydroxylase, an enzyme involved in tropane alkaloid biosynthesis, is localized at the pericycle of the root
    • Hashimoto T, Hayashi A, Amano Y, Kohno J, Iwanari H, Usuda S, Yamada Y (1991) Hyoscyamine 6β-hydroxylase, an enzyme involved in tropane alkaloid biosynthesis, is localized at the pericycle of the root. J Biol Chem 266:4648-4653
    • (1991) J Biol Chem , vol.266 , pp. 4648-4653
    • Hashimoto, T.1    Hayashi, A.2    Amano, Y.3    Kohno, J.4    Iwanari, H.5    Usuda, S.6    Yamada, Y.7
  • 30
    • 0001180010 scopus 로고
    • Production of tropane alkaloids in genetically engineered root cultures
    • Hashimoto T, Yun DJ, Yamada Y (1993) Production of tropane alkaloids in genetically engineered root cultures. Phytochemistry 32:713-718
    • (1993) Phytochemistry , vol.32 , pp. 713-718
    • Hashimoto, T.1    Yun, D.J.2    Yamada, Y.3
  • 31
    • 32644476854 scopus 로고    scopus 로고
    • Expression of the Arabidopsis feedback-insensitive anthranilate synthase holoenzyme and tryptophan decarboxylase genes in Catharanthus roseus hairy roots
    • Hong SB, Peebles CAM, Shanks JV, San KY, Gibson SI (2006) Expression of the Arabidopsis feedback-insensitive anthranilate synthase holoenzyme and tryptophan decarboxylase genes in Catharanthus roseus hairy roots. J Biotechnol 122:28-38
    • (2006) J Biotechnol , vol.122 , pp. 28-38
    • Hong, S.B.1    Peebles, C.A.M.2    Shanks, J.V.3    San, K.Y.4    Gibson, S.I.5
  • 32
    • 0034490132 scopus 로고    scopus 로고
    • Indole alkaloid biosynthesis in Catharanthus roseus: New enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase
    • Irmler S, Schröder G, St-Pierre B, Crouch NP, Hotze M, Schmidt J, Strack D, Matern U, Schröder J (2000) Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase. Plant J 24:797-804
    • (2000) Plant J , vol.24 , pp. 797-804
    • Irmler, S.1    Schröder, G.2    St-Pierre, B.3    Crouch, N.P.4    Hotze, M.5    Schmidt, J.6    Strack, D.7    Matern, U.8    Schröder, J.9
  • 33
    • 33846597097 scopus 로고    scopus 로고
    • Identification of a WRKY protein as a transcriptional regulator of benzylisoquinoline alkaloid biosynthesis in Coptis japonica
    • Kato N, Dubouzet E, Kokabu Y, Yoshida S, Taniguchi Y, Dubouzet JG, Yazaki K, Sato F (2007) Identification of a WRKY protein as a transcriptional regulator of benzylisoquinoline alkaloid biosynthesis in Coptis japonica. Plant Cell Physiol 48:8-18
    • (2007) Plant Cell Physiol , vol.48 , pp. 8-18
    • Kato, N.1    Dubouzet, E.2    Kokabu, Y.3    Yoshida, S.4    Taniguchi, Y.5    Dubouzet, J.G.6    Yazaki, K.7    Sato, F.8
  • 34
    • 44349195100 scopus 로고    scopus 로고
    • COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine
    • Katsir L, Schilmiller AL, Staswick PE, He SY, Howe GA (2008) COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine. Proc Natl Acad Sci USA 105:7100-7105
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7100-7105
    • Katsir, L.1    Schilmiller, A.L.2    Staswick, P.E.3    He, S.Y.4    Howe, G.A.5
  • 35
    • 39149126404 scopus 로고    scopus 로고
    • Pathogen resistance in transgenic tobacco plants producing caffeine
    • Kim Y-S, Sano H (2008) Pathogen resistance in transgenic tobacco plants producing caffeine. Phytochemistry 69:882-888
    • (2008) Phytochemistry , vol.69 , pp. 882-888
    • Kim, Y.-S.1    Sano, H.2
  • 37
    • 18044396993 scopus 로고    scopus 로고
    • A role for intra- and intercellular translocation in natural product biosynthesis
    • Kutchan TM (2005) A role for intra- and intercellular translocation in natural product biosynthesis. Curr Opin Plant Biol 8:292-300
    • (2005) Curr Opin Plant Biol , vol.8 , pp. 292-300
    • Kutchan, T.M.1
  • 39
    • 37749042422 scopus 로고    scopus 로고
    • Application of carborundum abrasion for investigating the leaf epidermis: Molecular cloning of Catharanthus roseus 16-hydroxytabersonine-16-O- methyltransferase
    • Levac D, Murata J, Kim WS, De Luca V (2008) Application of carborundum abrasion for investigating the leaf epidermis: molecular cloning of Catharanthus roseus 16-hydroxytabersonine-16-O-methyltransferase. Plant J 53:225-236
    • (2008) Plant J , vol.53 , pp. 225-236
    • Levac, D.1    Murata, J.2    Kim, W.S.3    De Luca, V.4
  • 41
    • 33646592543 scopus 로고    scopus 로고
    • Functional genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement
    • Li R, Reed DW, Liu E, Nowak J, Pelcher LE, Page JE, Covello PS (2006) Functional genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement. Chem Biol 13:513-520
    • (2006) Chem Biol , vol.13 , pp. 513-520
    • Li, R.1    Reed, D.W.2    Liu, E.3    Nowak, J.4    Pelcher, L.E.5    Page, J.E.6    Covello, P.S.7
  • 42
    • 4944264246 scopus 로고    scopus 로고
    • Camptothecin, over four decades of surprising findings
    • Lorence A, Nessler CL (2004) Camptothecin, over four decades of surprising findings. Phytochemistry 65:2735-2749
    • (2004) Phytochemistry , vol.65 , pp. 2735-2749
    • Lorence, A.1    Nessler, C.L.2
  • 44
    • 17144406830 scopus 로고    scopus 로고
    • Crystal structure of vinorine synthase, the first representative of the BAHD superfamily
    • Ma X, Koepke J, Panjikar S, Fritzsch G, Stöckigt J (2005) Crystal structure of vinorine synthase, the first representative of the BAHD superfamily. J Biol Chem 280:13576-13583
    • (2005) J Biol Chem , vol.280 , pp. 13576-13583
    • Ma, X.1    Koepke, J.2    Panjikar, S.3    Fritzsch, G.4    Stöckigt, J.5
  • 45
    • 33745473834 scopus 로고    scopus 로고
    • The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins
    • Ma X, Panjikar S, Koepke J, Loris E, Stöckigt J (2006) The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins. Plant Cell 18:907-920
    • (2006) Plant Cell , vol.18 , pp. 907-920
    • Ma, X.1    Panjikar, S.2    Koepke, J.3    Loris, E.4    Stöckigt, J.5
  • 46
    • 33947418152 scopus 로고    scopus 로고
    • Cellular and sub-cellular organization of the monoterpenoid indole alkaloid pathway in Catharanthus roseus
    • Mahroug S, Burlat V, St-Pierre B (2007) Cellular and sub-cellular organization of the monoterpenoid indole alkaloid pathway in Catharanthus roseus. Phytochem Rev 6:363-381
    • (2007) Phytochem Rev , vol.6 , pp. 363-381
    • Mahroug, S.1    Burlat, V.2    St-Pierre, B.3
  • 47
    • 0036315482 scopus 로고    scopus 로고
    • Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis
    • Mattern-Dogru E, Ma X, Hartmann J, Decker H, Stöckigt J (2002) Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis. Eur J Biochem 269:2889-2896
    • (2002) Eur J Biochem , vol.269 , pp. 2889-2896
    • Mattern-Dogru, E.1    Ma, X.2    Hartmann, J.3    Decker, H.4    Stöckigt, J.5
  • 48
    • 34250630530 scopus 로고    scopus 로고
    • The structure of two N-methyltransferases from the caffeine biosynthetic pathway
    • McCarthy AA, McCarthy JG (2007) The structure of two N-methyltransferases from the caffeine biosynthetic pathway. Plant Physiol 144:879-889
    • (2007) Plant Physiol , vol.144 , pp. 879-889
    • McCarthy, A.A.1    McCarthy, J.G.2
  • 49
    • 0000688846 scopus 로고
    • Expression of enzymatically active and correctly targeted strictosidine synthase in transgenic tobacco plants
    • McKnight TD, Bergey DR, Burnett RJ, Nessler CL (1991) Expression of enzymatically active and correctly targeted strictosidine synthase in transgenic tobacco plants. Planta 185:148-152
    • (1991) Planta , vol.185 , pp. 148-152
    • McKnight, T.D.1    Bergey, D.R.2    Burnett, R.J.3    Nessler, C.L.4
  • 50
    • 0033575710 scopus 로고    scopus 로고
    • A novel jasmonate- and elicitorresponsive element in the periwinkle secondary metabolite biosynthetic gene Str interacts with a jasmonate- and elicitor-inducible AP2-domain transcription factor, ORCA2
    • Menke FLH, Champion A, Kijne JW, Memelink J (1999) A novel jasmonate- and elicitorresponsive element in the periwinkle secondary metabolite biosynthetic gene Str interacts with a jasmonate- and elicitor-inducible AP2-domain transcription factor, ORCA2. EMBO J 18:4455-4463
    • (1999) EMBO J , vol.18 , pp. 4455-4463
    • Menke, F.L.H.1    Champion, A.2    Kijne, J.W.3    Memelink, J.4
  • 52
    • 0036439059 scopus 로고    scopus 로고
    • Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells
    • Morishige T, Dubouzet E, Choi KB, Yazaki K, Sato F (2002) Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells. Eur J Biochem 269:5659-5667
    • (2002) Eur J Biochem , vol.269 , pp. 5659-5667
    • Morishige, T.1    Dubouzet, E.2    Choi, K.B.3    Yazaki, K.4    Sato, F.5
  • 54
    • 33644674347 scopus 로고    scopus 로고
    • Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O- methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus
    • Murata J, De Luca V (2005) Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus. Plant J 44:581-594
    • (2005) Plant J , vol.44 , pp. 581-594
    • Murata, J.1    De Luca, V.2
  • 55
    • 33746339948 scopus 로고    scopus 로고
    • Expressed sequence tags from Madagascar periwinkle (Catharanthus roseus)
    • Murata J, Bienzle D, Brandle JE, Sensen CW, De Luca V (2006) Expressed sequence tags from Madagascar periwinkle (Catharanthus roseus). FEBS Lett 580:4501-4507
    • (2006) FEBS Lett , vol.580 , pp. 4501-4507
    • Murata, J.1    Bienzle, D.2    Brandle, J.E.3    Sensen, C.W.4    De Luca, V.5
  • 56
    • 48249155450 scopus 로고    scopus 로고
    • The leaf epidermome of Catharanthus roseus reveals its biochemical specialization
    • Murata J, Roepke J, Gordon H, De Luca V (2008) The leaf epidermome of Catharanthus roseus reveals its biochemical specialization. Plant Cell 20:524-542
    • (2008) Plant Cell , vol.20 , pp. 524-542
    • Murata, J.1    Roepke, J.2    Gordon, H.3    De Luca, V.4
  • 57
    • 0033227533 scopus 로고    scopus 로고
    • Two tropinone reductases, that catalyze opposite stereospecific reductions in tropane alkaloid biosynthesis, are localized in plant root with different cellspecific patterns
    • Nakajima K, Hashimoto T (1999) Two tropinone reductases, that catalyze opposite stereospecific reductions in tropane alkaloid biosynthesis, are localized in plant root with different cellspecific patterns. Plant Cell Physiol 40:1099-1107
    • (1999) Plant Cell Physiol , vol.40 , pp. 1099-1107
    • Nakajima, K.1    Hashimoto, T.2
  • 59
    • 34548323862 scopus 로고    scopus 로고
    • Tropane and nicotine alkaloid biosynthesis-novel approaches towards biotechnological production of plant-derived pharmaceuticals
    • Oksman-Caldentey KM (2007) Tropane and nicotine alkaloid biosynthesis-novel approaches towards biotechnological production of plant-derived pharmaceuticals. Curr Pharm Biotechnol 8:203-210
    • (2007) Curr Pharm Biotechnol , vol.8 , pp. 203-210
    • Oksman-Caldentey, K.M.1
  • 60
    • 34547838647 scopus 로고    scopus 로고
    • Spatial distribution and hormonal regulation of gene products from methyl erythritol phosphate and monoterpene-secoiridoid pathways in Catharanthus roseus
    • Oudin A, Mahroug S, Courdavault V, Hervouet N, Zelwer C, Rodríguez-Concepción M, St-Pierre B, Burlat V (2007) Spatial distribution and hormonal regulation of gene products from methyl erythritol phosphate and monoterpene-secoiridoid pathways in Catharanthus roseus. Plant Mol Biol 65:13-30
    • (2007) Plant Mol Biol , vol.65 , pp. 13-30
    • Oudin, A.1    Mahroug, S.2    Courdavault, V.3    Hervouet, N.4    Zelwer, C.5    Rodríguez-Concepción, M.6    St-Pierre, B.7    Burlat, V.8
  • 61
    • 32544444288 scopus 로고    scopus 로고
    • Effects of terpenoid precursor feeding on Catharanthus roseus hairy roots over-expressing the alpha or the alpha and beta subunits of anthranilate synthase
    • Peebles CAM, Hong SB, Gibson SI, Shanks IV, San KY (2006) Effects of terpenoid precursor feeding on Catharanthus roseus hairy roots over-expressing the alpha or the alpha and beta subunits of anthranilate synthase. Biotechnol Bioeng 93:534-540
    • (2006) Biotechnol Bioeng , vol.93 , pp. 534-540
    • Peebles, C.A.M.1    Hong, S.B.2    Gibson, S.I.3    Shanks, I.V.4    San, K.Y.5
  • 63
    • 33845499750 scopus 로고    scopus 로고
    • Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants
    • Rosenthal C, Mueller U, Panjikar S, Sun L, Ruppert M, Zhao Y, Stöckigt J (2006) Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants. Acta Crystallogr Sect F Struct Biol Cryst Commun 62:1286-1289
    • (2006) Acta Crystallogr Sect F Struct Biol Cryst Commun , vol.62 , pp. 1286-1289
    • Rosenthal, C.1    Mueller, U.2    Panjikar, S.3    Sun, L.4    Ruppert, M.5    Zhao, Y.6    Stöckigt, J.7
  • 64
    • 33645737590 scopus 로고    scopus 로고
    • Heterologous expression, purification, crystallization and preliminary X-ray analysis of raucaffricine glucosidase, a plant enzyme specifically involved in Rauvolfia alkaloid biosynthesis
    • Ruppert M, Panjikar S, Barleben L, Stöckigt J (2006) Heterologous expression, purification, crystallization and preliminary X-ray analysis of raucaffricine glucosidase, a plant enzyme specifically involved in Rauvolfia alkaloid biosynthesis. Acta Crystallogr Sect F Struct Biol Cryst Commun 62:257-260
    • (2006) Acta Crystallogr Sect F Struct Biol Cryst Commun , vol.62 , pp. 257-260
    • Ruppert, M.1    Panjikar, S.2    Barleben, L.3    Stöckigt, J.4
  • 65
    • 0036707551 scopus 로고    scopus 로고
    • Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein
    • Sakai K, Shitan N, Sato F, Ueda K, Yazaki K (2002) Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein. J Exp Bot 53:1879-1886
    • (2002) J Exp Bot , vol.53 , pp. 1879-1886
    • Sakai, K.1    Shitan, N.2    Sato, F.3    Ueda, K.4    Yazaki, K.5
  • 66
    • 20444379109 scopus 로고    scopus 로고
    • Cell type-specific localization of transcripts encoding nine consecutive enzymes involved in protoberberine alkaloid biosynthesis
    • Samanani N, Park SU, Facchini PJ (2005) Cell type-specific localization of transcripts encoding nine consecutive enzymes involved in protoberberine alkaloid biosynthesis. Plant Cell 17:915-926
    • (2005) Plant Cell , vol.17 , pp. 915-926
    • Samanani, N.1    Park, S.U.2    Facchini, P.J.3
  • 67
    • 33746489315 scopus 로고    scopus 로고
    • The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy
    • Samanani N, Alcantara J, Bourgault R, Zulak KG, Facchini PJ (2006) The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy. Plant J 47:547-563
    • (2006) Plant J , vol.47 , pp. 547-563
    • Samanani, N.1    Alcantara, J.2    Bourgault, R.3    Zulak, K.G.4    Facchini, P.J.5
  • 68
    • 33845883022 scopus 로고    scopus 로고
    • Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding
    • Schmidt J, Boettcher C, Kuhnt C, Kutchan TM, Zenk MH (2007) Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding. Phytochemistry 68:189-202
    • (2007) Phytochemistry , vol.68 , pp. 189-202
    • Schmidt, J.1    Boettcher, C.2    Kuhnt, C.3    Kutchan, T.M.4    Zenk, M.H.5
  • 69
    • 0037457993 scopus 로고    scopus 로고
    • Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica
    • Shitan N, Bazin I, Dan K, Obata K, Kigawa K, Ueda K, Sato F, Forestier C, Yazaki K (2003) Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica. Proc Natl Acad Sci USA 100:751-756
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 751-756
    • Shitan, N.1    Bazin, I.2    Dan, K.3    Obata, K.4    Kigawa, K.5    Ueda, K.6    Sato, F.7    Forestier, C.8    Yazaki, K.9
  • 70
    • 47249118317 scopus 로고    scopus 로고
    • Jasmonate-induced nicotine formation in tobacco is mediated by tobacco COI1 and JAZ genes
    • Shoji T, Ogawa T, Hashimoto T (2008) Jasmonate-induced nicotine formation in tobacco is mediated by tobacco COI1 and JAZ genes. Plant Cell Physiol 49:1003-1012
    • (2008) Plant Cell Physiol , vol.49 , pp. 1003-1012
    • Shoji, T.1    Ogawa, T.2    Hashimoto, T.3
  • 71
    • 33845254128 scopus 로고    scopus 로고
    • Transcriptome analysis in Catharanthus roseus leaves and roots for comparative terpenoid indole alkaloid profiles
    • Shukla AK, Shasany AK, Gupta MM, Khanuja SP (2006) Transcriptome analysis in Catharanthus roseus leaves and roots for comparative terpenoid indole alkaloid profiles. J Exp Bot 57:3921-3932
    • (2006) J Exp Bot , vol.57 , pp. 3921-3932
    • Shukla, A.K.1    Shasany, A.K.2    Gupta, M.M.3    Khanuja, S.P.4
  • 72
    • 36348950840 scopus 로고    scopus 로고
    • Structural biology in plant natural product biosynthesis-architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis
    • Stöckigt J, Panjikar S (2007) Structural biology in plant natural product biosynthesis-architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis. Nat Prod Rep 24:1382-1400
    • (2007) Nat Prod Rep , vol.24 , pp. 1382-1400
    • Stöckigt, J.1    Panjikar, S.2
  • 73
    • 0032720893 scopus 로고    scopus 로고
    • Multicellular compartmentation of Catharanthus roseus alkaloid biosynthesis predicts intercellular translocation of a pathway intermediate
    • St-Pierre B, Vazquez-Flota FA, De Luca V (1999) Multicellular compartmentation of Catharanthus roseus alkaloid biosynthesis predicts intercellular translocation of a pathway intermediate. Plant Cell 11:887-900
    • (1999) Plant Cell , vol.11 , pp. 887-900
    • St-Pierre, B.1    Vazquez-Flota, F.A.2    De Luca, V.3
  • 74
    • 0033103656 scopus 로고    scopus 로고
    • Expression of Atropa belladonna putrescine N-methyltransferase gene in root pericycle
    • Suzuki K, Yamada Y, Hashimoto T (1999a) Expression of Atropa belladonna putrescine N-methyltransferase gene in root pericycle. Plant Cell Physiol 40:289-297
    • (1999) Plant Cell Physiol , vol.40 , pp. 289-297
    • Suzuki, K.1    Yamada, Y.2    Hashimoto, T.3
  • 75
    • 0033137062 scopus 로고    scopus 로고
    • An Atropa belladonna hyoscyamine 6β-hydroxylase gene is differentially expressed in the root pericycle and anthers
    • Suzuki K, Yun DJ, Chen XY, Yamada Y, Hashimoto T (1999b) An Atropa belladonna hyoscyamine 6β-hydroxylase gene is differentially expressed in the root pericycle and anthers. Plant Mol Biol 40:141-152
    • (1999) Plant Mol Biol , vol.40 , pp. 141-152
    • Suzuki, K.1    Yun, D.J.2    Chen, X.Y.3    Yamada, Y.4    Hashimoto, T.5
  • 77
    • 27144496759 scopus 로고    scopus 로고
    • Caffeine production in tobacco plants by simultaneous expression of three coffee N-methyltransferases and its potential as a pest repellent
    • Uefuji H, Tatsumi Y, Morimoto M, Kaothien-Nakayama P, Ogita S, Sano H (2005) Caffeine production in tobacco plants by simultaneous expression of three coffee N-methyltransferases and its potential as a pest repellent. Plant Mol Biol 59:221-227
    • (2005) Plant Mol Biol , vol.59 , pp. 221-227
    • Uefuji, H.1    Tatsumi, Y.2    Morimoto, M.3    Kaothien-Nakayama, P.4    Ogita, S.5    Sano, H.6
  • 78
    • 0034647914 scopus 로고    scopus 로고
    • ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism
    • van der Fits L, Memelink J (2000) ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism. Science 289:295-297
    • (2000) Science , vol.289 , pp. 295-297
    • Van Der Fits, L.1    Memelink, J.2
  • 79
    • 0035121285 scopus 로고    scopus 로고
    • The jasmonate-inducible AP2/ERF-domain transcription factor ORCA3 activates gene expression via interaction with a jasmonate-responsive promoter element
    • van der Fits L, Memelink J (2001) The jasmonate-inducible AP2/ERF-domain transcription factor ORCA3 activates gene expression via interaction with a jasmonate-responsive promoter element. Plant J 25:43-53
    • (2001) Plant J , vol.25 , pp. 43-53
    • Van Der Fits, L.1    Memelink, J.2
  • 81
    • 4644289320 scopus 로고    scopus 로고
    • The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum
    • Weid M, Ziegler J, Kutchan TM (2004) The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum. Proc Natl Acad Sci USA 101:13957-13962
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13957-13962
    • Weid, M.1    Ziegler, J.2    Kutchan, T.M.3
  • 82
    • 0037178212 scopus 로고    scopus 로고
    • Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase over-expressing transgenic cell line T22 of Catharanthus roseus
    • Whitmer S, van der Heijden R, Verpoorte R (2002) Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase over-expressing transgenic cell line T22 of Catharanthus roseus. J Biotechnol 96:193-203
    • (2002) J Biotechnol , vol.96 , pp. 193-203
    • Whitmer, S.1    Van Der Heijden, R.2    Verpoorte, R.3
  • 84
    • 43549119034 scopus 로고    scopus 로고
    • Substrate specificity and diastereoselectivity of strictosidine glucosidase, a key enzyme in monoterpene indole alkaloid biosynthesis
    • Yerkes N, Wu JX, McCoy E, Galan MC, Chen S, O'Connor SE (2008) Substrate specificity and diastereoselectivity of strictosidine glucosidase, a key enzyme in monoterpene indole alkaloid biosynthesis. Bioorg Med Chem Lett 18:3095-3098
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 3095-3098
    • Yerkes, N.1    Wu, J.X.2    McCoy, E.3    Galan, M.C.4    Chen, S.5    O'Connor, S.E.6
  • 85
    • 0027078552 scopus 로고
    • Metabolic engineering of medicinal plants: Transgenic Atropa belladonna with an improved alkaloid composition
    • Yun D-J, Hashimoto T, Yamada Y (1992) Metabolic engineering of medicinal plants: transgenic Atropa belladonna with an improved alkaloid composition. Proc Natl Acad Sci USA 89:11799-11803
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11799-11803
    • Yun, D.-J.1    Hashimoto, T.2    Yamada, Y.3
  • 86
    • 44949127129 scopus 로고    scopus 로고
    • Alkaloid biosynthesis: Metabolism and trafficking
    • Ziegler J, Facchini PJ (2008) Alkaloid biosynthesis: metabolism and trafficking. Annu Rev Plant Biol 59:735-769
    • (2008) Annu Rev Plant Biol , vol.59 , pp. 735-769
    • Ziegler, J.1    Facchini, P.J.2
  • 87
    • 33749241876 scopus 로고    scopus 로고
    • Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis
    • Ziegler J, Voigtländer S, Schmidt J, Kramell R, Miersch O, Ammer C, Gesell A, Kutchan TM (2006) Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis. Plant J 48:177-192
    • (2006) Plant J , vol.48 , pp. 177-192
    • Ziegler, J.1    Voigtländer, S.2    Schmidt, J.3    Kramell, R.4    Miersch, O.5    Ammer, C.6    Gesell, A.7    Kutchan, T.M.8


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