Duration of red blood cells storage and outcome in critically ill patients

Journal of Critical Care

Volumn 29, Issue 3, 2014, Pages 476.e1-476.e8

  Aubron, Cecile ^a   Bailey, Michael ^a   McQuilten, Zoe ^a,b   Pilcher, David ^a   Hegarty, Colin ^c   Martinelli, Anthony ^c   Magrin, Geoff ^d   Irving, David ^b   Cooper, D Jamie ^a   Bellomo, Rinaldo ^a  

^a MONASH UNIVERSITY   (Australia)

^b AUSTRALIAN RED CROSS BLOOD SERVICE   (Australia)

^c AUSTIN HOSPITAL   (Australia)

^d ALFRED HOSPITAL   (Australia)

Author keywords

Critically ill patients; Intensive care unit; Length of stay; Morbidity; Mortality; Outcome; Red blood cells storage duration; Transfusion

Indexed keywords

ADULT; ARTICLE; CRITICALLY ILL PATIENT; ERYTHROCYTE LIFESPAN; ERYTHROCYTE PRESERVATION; ERYTHROCYTE TRANSFUSION; FEMALE; HOSPITAL ADMISSION; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE ANALYSIS; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; RETROSPECTIVE STUDY; SENSITIVITY ANALYSIS; AGED; CRITICAL ILLNESS; ERYTHROCYTE; INTENSIVE CARE UNIT; LABORATORY DIAGNOSIS; MIDDLE AGED; TIME; UTILIZATION;

AGED; CRITICAL ILLNESS; ERYTHROCYTE TRANSFUSION; ERYTHROCYTES; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; RETROSPECTIVE STUDIES; SPECIMEN HANDLING; TIME FACTORS;

EID: 84899985861     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2014.01.006     Document Type: Article

References (48)

1. Zimrin A.B., Hess J.R. Current issues relating to the transfusion of stored red blood cells. Vox Sang 2009, 96(2):93-103.
2. Hess J.R. Red cell storage. J Proteomics 2010, 73(3):368-373.
3. Chin-Yee I., Arya N., d'Almeida M.S. The red cell storage lesion and its implication for transfusion. Transfus Sci 1997, 18(3):447-458.
4. van de Watering L. Red cell storage and prognosis. Vox Sang 2011, 100(1):36-45.
5. Bennett-Guerrero E., Veldman T.H., Doctor A., Telen M.J., Ortel T.L., Reid T.S., et al. Evolution of adverse changes in stored RBCs. Proc Natl Acad Sci U S A 2007, 104(43):17063-17068.
6. Marik P.E., Corwin H.L. Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature. Crit Care Med 2008, 36(9):2667-2674.
7. Hebert P.C., Wells G., Blajchman M.A., Marshall J., Martin C., Pagliarello G., et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 1999, 340(6):409-417.
8. Weinberg J.A., McGwin G., Griffin R.L., Huynh V.Q., Cherry S.A., Marques M.B., et al. Age of transfused blood: an independent predictor of mortality despite universal leukoreduction. J Trauma 2008, 65(2):279-282. [discussion 282-4].
9. Koch C.G., Li L., Sessler D.I., Figueroa P., Hoeltge G.A., Mihaljevic T., et al. Duration of red-cell storage and complications after cardiac surgery. N Engl J Med 2008, 358(12):1229-1239.
10. Eikelboom J.W., Cook R.J., Liu Y., Heddle N.M. Duration of red cell storage before transfusion and in-hospital mortality. Am Heart J 2010, 159(5):737-743. [e1].
11. Spinella P.C., Carroll C.L., Staff I., Gross R., Mc Quay J., Keibel L., et al. Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries. Crit Care 2009, 13(5):R151.
12. Robinson S.D., Janssen C., Fretz E.B., Berry B., Chase A.J., Siega A.D., et al. Red blood cell storage duration and mortality in patients undergoing percutaneous coronary intervention. Am Heart J 2010, 159(5):876-881.
13. Weinberg J.A., McGwin G., Marques M.B., Cherry S.A., Reiff D.A., Kerby J.D., et al. Transfusions in the less severely injured: does age of transfused blood affect outcomes?. J Trauma 2008, 65(4):794-798.
14. Vamvakas E.C., Carven J.H. Transfusion and postoperative pneumonia in coronary artery bypass graft surgery: effect of the length of storage of transfused red cells. Transfusion 1999, 39(7):701-710.
15. Leal-Noval S.R., Jara-Lopez I., Garcia-Garmendia J.L., Marin-Niebla A., Herruzo-Aviles A., Camacho-Larana P., et al. Influence of erythrocyte concentrate storage time on postsurgical morbidity in cardiac surgery patients. Anesthesiology 2003, 98(4):815-822.
16. Andreasen J.J., Dethlefsen C., Modrau I.S., Baech J., Schonheyder H.C., Moeller J.K., et al. Storage time of allogeneic red blood cells is associated with risk of severe postoperative infection after coronary artery bypass grafting. Eur J Cardiothorac Surg 2011, 39(3):329-334.
17. Offner P.J., Moore E.E., Biffl W.L., Johnson J.L., Silliman C.C. Increased rate of infection associated with transfusion of old blood after severe injury. Arch Surg 2002, 137(6):711-717.
18. Vandromme M.J., McGwin G., Marques M.B., Kerby J.D., Rue L.W., Weinberg J.A. Transfusion and pneumonia in the trauma intensive care unit: an examination of the temporal relationship. J Trauma 2009, 67(1):97-101.
19. Zallen G., Offner P.J., Moore E.E., Blackwell J., Ciesla D.J., Gabriel J., et al. Age of transfused blood is an independent risk factor for postinjury multiple organ failure. Am J Surg 1999, 178(6):570-572.
20. Keller M.E., Jean R., LaMorte W.W., Millham F., Hirsch E. Effects of age of transfused blood on length of stay in trauma patients: a preliminary report. J Trauma 2002, 53(5):1023-1025.
21. Murrell Z., Haukoos J.S., Putnam B., Klein S.R. The effect of older blood on mortality, need for ICU care, and the length of ICU stay after major trauma. Am Surg 2005, 71(9):781-785.
22. Wasser M.N., Houbiers J.G., D'Amaro J., Hermans J., Huysmans H.A., van Konijnenburg G.C., et al. The effect of fresh versus stored blood on post-operative bleeding after coronary bypass surgery: a prospective randomized study. Br J Haematol 1989, 72(1):81-84.
23. Schulman C.I., Nathe K., Brown M., Cohn S.M. Impact of age of transfused blood in the trauma patient. J Trauma 2002, 52(6):1224-1225.
24. Vamvakas E.C., Carven J.H. Length of storage of transfused red cells and postoperative morbidity in patients undergoing coronary artery bypass graft surgery. Transfusion 2000, 40(1):101-109.
25. van de Watering L., Lorinser J., Versteegh M., Westendord R., Brand A. Effects of storage time of red blood cell transfusions on the prognosis of coronary artery bypass graft patients. Transfusion 2006, 46(10):1712-1718.
26. Taylor R.W., O'Brien J., Trottier S.J., Manganaro L., Cytron M., Lesko M.F., et al. Red blood cell transfusions and nosocomial infections in critically ill patients. Crit Care Med 2006, 34(9):2302-2308. [quiz 2309].
27. Yap C.H., Lau L., Krishnaswamy M., Gaskell M., Yii M. Age of transfused red cells and early outcomes after cardiac surgery. Ann Thorac Surg 2008, 86(2):554-559.
28. McKenny M., Ryan T., Tate H., Graham B., Young V.K., Dowd N. Age of transfused blood is not associated with increased postoperative adverse outcome after cardiac surgery. Br J Anaesth 2011, 106(5):643-649.
29. van Straten A.H., Soliman Hamad M.A., van Zundert A.A., Martens E.J., ter Woorst J.F., de Wolf A.M., et al. Effect of duration of red blood cell storage on early and late mortality after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2011, 141(1):231-237.
30. Aubron C., Nichol A., Cooper D.J., Bellomo R. Age of red blood cells and transfusion in critically ill patients. Ann Intensive Care 2013, 3(1):2.
31. Pettila V., Westbrook A.J., Nichol A.D., Bailey M.J., Wood E.M., Syres G., et al. Age of red blood cells and mortality in the critically ill. Crit Care 2011, 15(2):R116.
32. Purdy F.R., Tweeddale M.G., Merrick P.M. Association of mortality with age of blood transfused in septic ICU patients. Can J Anaesth 1997, 44(12):1256-1261.
33. Gajic O., Rana R., Mendez J.L., Rickman O.B., Lymp J.F., Hubmayr R.D., et al. Acute lung injury after blood transfusion in mechanically ventilated patients. Transfusion 2004, 44(10):1468-1474.
34. Hebert P.C., Chin-Yee I., Fergusson D., Blajchman M., Martineau R., Clinch J., et al. A pilot trial evaluating the clinical effects of prolonged storage of red cells. Anesth Analg 2005, 100(5):1433-1438. [table of contents].
35. Gajic O., Rana R., Winters J.L., Yilmaz M., Mendez J.L., Rickman O.B., et al. Transfusion-related acute lung injury in the critically ill: prospective nested case-control study. Am J Respir Crit Care Med 2007, 176(9):886-891.
36. van Buskirk C.M., Thakur S.J., Murray D.L., Bryant S.C., Winters J.L., Stubbs J.R., et al. Red Blood Cell Storage Age Has No Impact on Clinical Outcome in Critically Ill Patients. Transfusion 2009, 49:S18010D. [Supplement].
37. Katsios C., Griffith L., Spinella P., Lacroix J., Crowther M., Hebert P., et al. Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical and surgical critically ill patients: a prospective observational cohort study. Crit Care 2011, 15(6):R263.
38. Kor D.J., Gajic O. Blood product transfusion in the critical care setting. Curr Opin Crit Care 2012, 16(4):309-316.
39. Vamvakas E.C. Meta-analysis of clinical studies of the purported deleterious effects of "old" (versus "fresh") red blood cells: are we at equipoise?. Transfusion 2010, 50(3):600-610.
40. Wang D., Sun J., Solomon S.B., Klein H.G., Natanson C. Transfusion of older stored blood and risk of death: a meta-analysis. Transfusion 2012, 52(6):1184-1195.
41. Vincent J.L., Baron J.F., Reinhart K., Gattinoni L., Thijs L., Webb A., et al. Anemia and blood transfusion in critically ill patients. JAMA 2002, 288(12):1499-1507.
42. Corwin H.L., Gettinger A., Pearl R.G., Fink M.P., Levy M.M., Abraham E., et al. The CRIT Study: Anemia and blood transfusion in the critically ill-current clinical practice in the United States. Crit Care Med 2004, 32(1):39-52.
43. National Health and Medical Research Council (NHMRC), Australasian Society of Blood Transfusion (ASBT) Clinical practice guidelines on the use of blood components 2001, [Canberra, Australia]. NHMRC (Ed.).
44. Blood Observational Study Investigators-ANZICS-CTG Transfusion practice and guidelines in Australian and New Zealand intensive care units. Intensive Care Med 2010, 36:1138-1146.
45. Weinberg J.A., McGwin G., Vandromme M.J., Marques M.B., Melton S.M., Reiff D.A., et al. Duration of red cell storage influences mortality after trauma. J Trauma 2010, 69(6):1427-1432.
46. Sanders J., Patel S., Cooper J., Berryman J., Farrar D., Mythen M., et al. Red blood cell storage is associated with length of stay and renal complications after cardiac surgery. Transfusion 2011, 51(11):2286-2294.
47. van de Watering L. Pitfalls in the current published observational literature on the effects of red blood cell storage. Transfusion 2011, 51(8):1847-1854.
48. Vlaar A.P., Hofstra J.J., Levi M., Kulik W., Nieuwland R., Tool A.T., et al. Supernatant of aged erythrocytes causes lung inflammation and coagulopathy in a "two-hit" in vivo syngeneic transfusion model. Anesthesiology 2010, 113(1):92-103.