Pain exacerbates chronic mild stress-induced changes in noradrenergic transmission in rats

European Neuropsychopharmacology

Volumn 24, Issue 6, 2014, Pages 996-1003

  Bravo, Lidia ^a,b   Torres Sanchez, Sonia ^a,b   Alba Delgado, Cristina ^a,b   Mico, Juan A ^a,b   Berrocoso, Esther ^a,b  

^a UNIVERSITY OF CÁDIZ   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

Author keywords

Comorbidity; Depression; Locus coeruleus; Pain; Stress; Tyrosine hydroxylase

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; NORADRENALIN TRANSPORTER; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC CONSTRICTION INJURY; CHRONIC PAIN; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; DISEASE EXACERBATION; ELECTROPHYSIOLOGY; EXPERIMENTAL MODEL; IMMUNOFLUORESCENCE; LOCUS CERULEUS; MALE; NEUROPATHIC PAIN; NEUROTRANSMISSION; NONHUMAN; NORADRENERGIC SYSTEM; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; ACTION POTENTIAL; ANIMAL; CELL SIZE; CHRONIC DISEASE; COMORBIDITY; DEPRESSIVE DISORDER; DISEASE MODEL; EPIDEMIOLOGY; MENTAL STRESS; METABOLISM; NERVE CELL; NEURALGIA; PATHOLOGY; PHYSIOLOGY; SCIATIC NERVE; SPRAGUE DAWLEY RAT; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANIMALS; CELL SIZE; CHRONIC DISEASE; CHRONIC PAIN; COMORBIDITY; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; LOCUS COERULEUS; MALE; NEURALGIA; NEURONS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; SCIATIC NERVE; STRESS, PSYCHOLOGICAL; SYNAPTIC TRANSMISSION; TYROSINE 3-MONOOXYGENASE;

EID: 84899985808     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2014.01.011     Document Type: Article

References (20)

1. Alba-Delgado C., Borges G., Sanchez-Blazquez P., Ortega J.E., Horrillo I., Mico J.A., Meana J.J., Neto F., Berrocoso E. The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain. Psychopharmacology (Berl) 2012, 221:53-65.
2. Alba-Delgado C., Llorca-Torralba M., Horrillo I., Ortega J.E., Mico J.A., Sanchez-Blazquez P., Meana J.J., Berrocoso E. Chronic pain leads to concomitant noradrenergic impairment and mood disorders. Biol. Psychiatry 2013, 73:54-62.
3. Bair M.J., Robinson R.L., Eckert G.J., Stang P.E., Croghan T.W., Kroenke K. Impact of pain on depression treatment response in primary care. Psychosom. Med. 2004, 66:17-22.
4. Bennett G.J., Xie Y.K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1988, 33:87-107.
5. Berridge C.W., Abercrombie E.D. Relationship between locus coeruleus discharge rates and rates of norepinephrine release within neocortex as assessed by in vivo microdialysis. Neuroscience 1999, 93:1263-1270.
6. Berrocoso E., Mico J.A. In vivo effect of venlafaxine on locus coeruleus neurons: role of opioid, alpha(2)-adrenergic, and 5-hydroxytryptamine(1A) receptors. J. Pharmacol. Exp. Ther. 2007, 322:101-107.
7. Berrocoso E., Mico J.A., Vitton O., Ladure P., Newman-Tancredi A., Depoortere R., Bardin L. Evaluation of milnacipran, in comparison with amitriptyline, on cold and mechanical allodynia in a rat model of neuropathic pain. Eur. J. Pharmacol. 2011, 655:46-51.
8. Bravo L., Alba-Delgado C., Torres-Sanchez S., Mico J.A., Neto F.L., Berrocoso E. Social stress exacerbates the aversion to painful experiences in rats exposed to chronic pain: the role of the locus coeruleus. Pain 2013, 154:2014-2023.
9. Bravo L., Mico J.A., Rey-Brea R., Perez-Nievas B., Leza J.C., Berrocoso E. Depressive-like states heighten the aversion to painful stimuli in a rat model of comorbid chronic pain and depression. Anesthesiology 2012, 117:613-625.
10. Detke M.J., Rickels M., Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology (Berl) 1995, 121:66-72.
11. Dimitrov E.L., Yanagawa Y., Usdin T.B. Forebrain GABAergic projections to locus coeruleus in mouse. J. Comp. Neurol. 2013, 521:2373-2397.
12. Florin-Lechner S.M., Druhan J.P., Aston-Jones G., Valentino R.J. Enhanced norepinephrine release in prefrontal cortex with burst stimulation of the locus coeruleus. Brain Res. 1996, 742:89-97.
13. German D.C., Nelson O., Liang F., Liang C.L., Games D. The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage. J. Comp. Neurol. 2005, 492:469-476.
14. Haidkind R., Eller M., Harro M., Kask A., Rinken A., Oreland L., Harro J. Effects of partial locus coeruleus denervation and chronic mild stress on behaviour and monoamine neurochemistry in the rat. Eur. Neuropsychopharmacol. 2003, 13:19-28.
15. Karp J.F., Scott J., Houck P., Reynolds C.F., Kupfer D.J., Frank E. Pain predicts longer time to remission during treatment of recurrent depression. J. Clin. Psychiatry 2005, 66:591-597.
16. Kitayama I., Yaga T., Kayahara T., Nakano K., Murase S., Otani M., Nomura J. Long-term stress degenerates, but imipramine regenerates, noradrenergic axons in the rat cerebral cortex. Biol. Psychiatry 1997, 42:687-696.
17. Kitayama I.T., Otani M., Murase S. Degeneration of the locus ceruleus noradrenergic neurons in the stress-induced depression of rats. Ann. NY Acad. Sci. 2008, 1148:95-98.
18. Meyer J.H., Ginovart N., Boovariwala A., Sagrati S., Hussey D., Garcia A., Young T., Praschak-Rieder N., Wilson A.A., Houle S. Elevated monoamine oxidase a levels in the brain: an explanation for the monoamine imbalance of major depression. Arch. Gen. Psychiatry 2006, 63:1209-1216.
19. Polak P.E., Kalinin S., Feinstein D.L. Locus coeruleus damage and noradrenaline reductions in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain 2011, 134:665-677.
20. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110.