Community Case Clusters of Middle East Respiratory Syndrome Coronavirus in Hafr Al-Batin, Kingdom of Saudi Arabia: A Descriptive Genomic study

International Journal of Infectious Diseases

Volumn 23, Issue , 2014, Pages 63-68

  Memish, Ziad A ^a,b   Cotten, Matthew ^c   Watson, Simon J ^c   Kellam, Paul ^c   Zumla, Alimuddin ^d   Alhakeem, Rafat F ^a   Assiri, Abdullah ^a   Rabeeah, Abdullah A Al ^a   Al Tawfiq, Jaffar A ^e  

^a MINISTRY OF HEALTH   (Saudi Arabia)

^b ALFAISAL UNIVERSITY   (Saudi Arabia)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Clusters; Community; Coronavirus; Genome; MERS CoV; Middle East; Phylogeny; Virus transmission

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CAMEL; CASE CONTROL STUDY; CHILD; CLINICAL ARTICLE; CLUSTER ANALYSIS; COMMUNITY ACQUIRED INFECTION; COMORBIDITY; CORONAVIRUS; DISEASE TRANSMISSION; EPIDEMIOLOGICAL DATA; EXPOSURE; FEMALE; GENOMICS; HOST; HOST PARASITE INTERACTION; HUMAN; MALE; MEDICAL INFORMATION; MIDDLE EAST; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MOLECULAR DIAGNOSIS; NONHUMAN; PRESCHOOL CHILD; RESERVOIR; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAUDI ARABIA; VIRUS INFECTION; ANIMAL; CONTACT EXAMINATION; CORONAVIRUS INFECTIONS; EPIDEMIOLOGY; GENETICS; ISOLATION AND PURIFICATION; MIDDLE AGED; PHYLOGENY; TRANSMISSION; VIROLOGY; VIRUS GENOME; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANIMALS; CAMELS; CHILD; CHILD, PRESCHOOL; COMORBIDITY; CONTACT TRACING; CORONAVIRUS INFECTIONS; FEMALE; GENOME, VIRAL; HUMANS; MALE; MIDDLE AGED; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; PHYLOGENY; SAUDI ARABIA; YOUNG ADULT;

EID: 84899973386     PISSN: 12019712     EISSN: 18783511     Source Type: Journal    
DOI: 10.1016/j.ijid.2014.03.1372     Document Type: Article

References (32)

1. Zaki A.M., van Boheemen S., Bestebroer T.M., Osterhaus A.D., Fouchier R.A. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 2012, 367:1814-1820.
2. WHO. Middle East respiratory syndrome coronavirus (MERS-CoV) - update.27 March 2014. 2014. http://www.whoint/csr/don/2014_03_27_mers/en/.
3. Memish ZA, Zumla AI, Al-Hakeem RF, Al-Rabeeah AA, Stephens GM. Family cluster of Middle East respiratory syndrome coronavirus infections. N Engl J Med. 2013 Jun 27;368(26):2487-94. Epub 2013 May 29. Erratum in: N Engl J Med. 2013 Aug 8;369(6):587. doi:10.1056/NEJMoa1303729.
4. Assiri A, McGeer A, Perl TM, Price CS, Al Rabeeah AA, Cummings DA et al., KSA MERS-CoV Investigation Team. Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med. 2013 Aug 1;369(5):407-16. Epub 2013 Jun 19. Erratum in: N Engl J Med. 2013 Aug 29;369(9):886. doi:10.1056/NEJMoa1306742.
5. Reusken C.B., Haagmans B.L., Muller M.A., Gutierrez C., Godeke G.J., et al. Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study. Lancet Infect Dis 2013, 13:859-866.
6. Hemida MG, Perera RA, Wang P, Alhammadi MA, Siu LY, et al. Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013. Euro Surveill 2013; 18: 20659.
7. Perera RA, Wang P, Gomaa MR, El-Shesheny R, Kandeil A, et al. Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013. Euro Surveill 2013;18: pii=20574.
8. Haagmans B.L., Al Dhahiry S.H., Reusken C.B., Raj V.S., Galiano M., et al. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation. Lancet Infect Dis 2014, 14:140-145.
9. Harrigan P, Bjurström L. Heads High. Saudi Aramco World. May/June 2008, 59 (3):48-57. Available at:. https://www.saudiaramcoworld.com/issue/200803/heads.high.htm.
10. Cotten M.W.S., Zumla A.I., Makhdoom H.Q., Palser A.L., Ong S.H., Al Rabeeah A.A., et al. Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirus. mBio 2014, 5. e01062-01013.
11. Cauchemez S, Fraser C, Van Kerkhove MD, Donnelly CA, Riley S, et al. (2013) Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility. The Lancet Infectious Diseases: doi:pii: S1473-3099(1413)70304-70309.
12. Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis. 2013 Sep;13(9):752-61. doi:10.1016/S1473-3099(13)70204-4.
13. Cotten M., Watson S.J., Kellam P., Al-Rabeeah A.A., Makhdoom H.Q., Assiri A., et al. Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study. Lancet 2013 Dec 14, 382(9909):1993-2002.
14. WHO. Interim surveillance recommendations for human infection with Middle East respiratory syndrome coronavirus. Available at: Last accessed march 18, 2014. http://www.who.int/csr/disease/coronavirus_infections/InterimRevisedSurveillanceRecommendations_nCoVinfection_27Jun13.pdf.
15. Guery B., Poissy J., el Mansouf L., Sejourne C., Ettahar N., et al. Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission. Lancet 2013, 381:2265-2272.
16. Mailles A., Blanckaert K., Chaud P., van der Werf S., Lina B., et al. First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission, France, May 2013. Euro Surveill 2013, 18.
17. Hijawi B., Abdallat M., Sayaydeh A., Alqasrawi S., Haddadin A., et al. Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East Mediterr Health J 2013, 19(Suppl 1):S12-S18.
18. Omrani A.S., Matin M.A., Haddad Q., Al-Nakhli D., Memish Z.A., et al. A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case. Int J Infect Dis 2013, 17:e668-e672.
19. WHO (2013) MERS-CoV summary and literature update - as of 20 June 2013. Last accessed March 18, 2014. http://wwwwhoint/csr/disease/coronavirus_infections/update_20130620/en/indexhtml.
20. Health Protection Agency (HPA) UK Novel Coronavirus Investigation team. Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013. Euro Surveill. 2013 Mar 14;18(11):20427.
21. Penttinen P.M., Kaasik-Aaslav K., Friaux A., Donachie A., Sudre B., Amato-GauciAJ, et al. Taking stock of the first 133 MERS coronavirus cases globally--Is the epidemic changing?. Euro Surveill 2013 Sep 26, 18(39). pii: 20596.
22. ProMED-mail (2013) Novel coronavirus infection - update 22 May 2013. http://wwwpromedmailorg/directphp%3Fid=201305221730663.
23. The WHOMers-Cov Research Group. State of Knowledge and Data Gaps of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Humans. PLoSCurr. 2013 Nov 12;5. pii: ecurrents.outbreaks.0bf719e352e7478f8ad85fa30127ddb8.
24. Albarrak A.M., Stephens G.M., Hewson R., Memish Z.A. Recovery from severe novel coronavirus infection. Saudi Med J 2012, 33:1265-1269.
25. Drosten C., Seilmaier M., CormanVM, Hartmann W., Scheible G., et al. Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. Lancet Infect Dis 2013, 13:745-751.
26. Pebody R.G., Chand M.A., Thomas H.L., Green H.K., Boddington N.L., et al. The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012. Euro Surveill 2012, 17:20292.
27. Memish ZA, Al-Tawfiq JA, Makhdoom HQ, Al-Rabeeah AA, Assiri A, AlhakeemRF et al. Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive study. ClinMicrobiol Infect. 2014 Jan 24. [Epub ahead of print]. doi:10.1111/1469-0691.12562.
28. Memish Z.A., Al-Tawfiq J.A., Assiri A. Hospital-associated Middle East respiratory syndrome coronavirus infections. N Engl J Med 2013 Oct 31, 369(18):1761-1762.
29. Al-Tawfiq J.A., Assiri A., Memish Z.A. Middle East respiratory syndrome novel corona MERS-CoV infection. Epidemiology and outcome update. Saudi Med J 2013 Oct, 34(10):991-994.
30. Memish Z.A., Cotten M., Meyer B., et al. Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013. Emerg Infect Dis 2014.
31. Chu D.K.W., Poon L.L.M., Gomaa M.M., et al. MERS Coronaviruses in Dromedary Camels, Egypt. Emerg Infect Dis 2014, 20.
32. Breban R., Riou J., Fontanet A. Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk. Lancet 2013, 382:694-699.