TRPM7 is involved in angiotensin II induced cardiac fibrosis development by mediating calcium and magnesium influx

Cell Calcium

Volumn 55, Issue 5, 2014, Pages 252-260

  Yu, Yang ^a   Chen, Shaorui ^a   Xiao, Chuyao ^a   Jia, Yanyan ^a   Guo, Jinlei ^a   Jiang, Jianmin ^a   Liu, Peiqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Calcium; Cardiac fibrosis; Magnesium; TRPM7

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN II; CALCIUM ION; CONNECTIVE TISSUE GROWTH FACTOR; MAGNESIUM ION; SHORT HAIRPIN RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; 2-AMINOETHOXYDIPHENYL BORATE; ACTIN; BORON DERIVATIVE; CALCIUM; CDKN1B PROTEIN, RAT; CTGF PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MAGNESIUM; NERVE PROTEIN; NFATC4 PROTEIN, RAT; SMALL INTERFERING RNA; SMOOTH MUSCLE ACTIN, RAT; TRANSCRIPTION FACTOR NFAT; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM7 PROTEIN, RAT;

ADULT; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CARDIAC FIBROBLAST; CATION TRANSPORT; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CELL VIABILITY ASSAY; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; FIBROBLAST; HEART MUSCLE FIBROSIS; MAGNESIUM INFLUX; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; FIBROSIS; GENETICS; MALE; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ACTINS; ANGIOTENSIN II; ANIMALS; BORON COMPOUNDS; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; FIBROBLASTS; FIBROSIS; MAGNESIUM; MALE; NERVE TISSUE PROTEINS; NFATC TRANSCRIPTION FACTORS; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRPM CATION CHANNELS;

EID: 84899961976     PISSN: 01434160     EISSN: 15321991     Source Type: Journal    
DOI: 10.1016/j.ceca.2014.02.019     Document Type: Article

References (33)

1. Sun Y., Zhang J.Q., Zhang J., Lamparter S. Cardiac remodeling by fibrous tissue after infarction in rats. J. Lab. Clin. Med. 2000, 135:316-323.
2. Banerjee I., Fuseler J.W., Price R.L., Borg T.K., Baudino T.A. Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am. J. Physiol. Heart Circ. Physiol. 2007, 293:H1883-H1891.
3. Hinz B., Phan S.H., Thannickal V.J., et al. The myofibroblast: one function, multiple origins. Am. J. Pathol. 2007, 170:1807-1816.
4. Oh-hora M., Rao A. Calcium signaling in lymphocytes. Curr. Opin. Immunol. 2008, 20:250-258.
5. Berridge M.J., Bootman M.D., Roderick H.L. Calcium signalling: dynamics, homeostasis and remodeling. Nat. Rev. Mol. Cell Biol. 2003, 4:517-529.
6. Brown M.J., McInnes G.T., Papst C.C., Zhang J., MacDonald T.M. Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial. Lancet 2011, 377:312-320.
7. Finckenberg P., Inkinen K., Ahonen J., et al. Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways. Am. J. Pathol. 2003, 163:355-366.
8. 2+ in aortic and cerebral vascular smooth muscle cells: possible links to hypertension, atherogenesis, and stroke. Am. J. Hypertens. 2003, 16:701-707.
9. 2+ exchanger. Clin. Sci. (Lond.) 2003, 105:235-242.
10. Baldoli E., Maier J.A. Silencing TRPM7 mimics the effects of magnesium deficiency in human microvascular endothelial cells. Angiogenesis 2012, 15:47-57.
11. Hardie R.C. TRP channels and lipids: from Drosophila to mammalian physiology. J. Physiol. 2007, 578:9-24.
12. Ryazanova L.V., Rondon L.J., et al. TRPM7 is essential for Mg (2+) homeostasis in mammals. Nat. Commun. 2010, 1:109.
13. 2+ signals confer fibrogenesis in human atrial fibrillation. Circ. Res. 2010, 106:992-1003.
14. Olson E.R., Shamhart P.E., Naugle J.E., Meszaros J.G. Angiotensin II-induced extracellular signal-regulated kinase 1/2 activation is mediated by protein kinase Cdelta and intracellular calcium in adult rat cardiac fibroblasts. Hypertension 2008, 51:704-711.
15. 2+ signaling in bovine vascular endothelial cells. Am. J. Physiol. Cell Physiol. 2007, 293:C106-C118.
16. Li D., Liu X., et al. MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J. Biol. Chem. 2011, 286:36677-36685.
17. Olson E.R., Naugle J.E., Zhang X., Bomser J.A., Meszaros J.G. Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1131-H1138.
18. Leask A. Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, in fibroblast activation. Circ. Res. 2010, 106:1675-1680.
19. Fujii T., Onohara N., et al. Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. J. Biol. Chem. 2005, 280:23041-23047.
20. Herum K.M., Lunde I.G., Skrbic B., et al. Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress. J. Mol. Cell. Cardiol. 2013, 54:73-81.
21. Sahni J., Tamura R., Sweet I.R., Scharenberg A.M. TRPM7 regulates quiescent/proliferative metabolic transitions in lymphocytes. Cell Cycle 2010, 9:3565-3574.
22. Brilla C.G., Scheer C., Rupp H. Angiotensin II and intracellular calcium of adult cardiac fibroblasts. J. Mol. Cell. Cardiol. 1998, 30:1237-1246.
23. He Y., Yao G., Savoia C., Touyz R.M. Transient receptor potential melastatin 7 ion channels regulate magnesium.homeostasis in vascular smooth muscle cells: role of angiotensin II. Circ. Res. 2005, 96:207-215.
24. Kania G., Blyszczuk P., Eriksson U. Mechanisms of cardiac fibrosis in inflammatory heart disease. Trends Cardiovasc. Med. 2009, 19:247-252.
25. Thodeti C.K., Paruchuri S., Meszaros J.G. A TRP to cardiac fibroblast differentiation. Channels (Austin) 2013, 7:211-214.
26. Adapala R.K., Thoppil R.J., Luther D.J., et al. TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals. J. Mol. Cell. Cardiol. 2013, 54:45-52.
27. Davis J., Burr A.R., Davis G.F., Birnbaumer L., Molkentin J.D. A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev. Cell. 2012, 23:705-715.
28. Reddy V.S., Harskamp R.E., van Ginkel M.W., et al. Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-kappaB activation. J. Cell. Physiol. 2008, 215:697-707.
29. Zhang W., Xu C. Calcium sensing receptor and heart diseases. Pathophysiology 2009, 16:317-323.
30. 2+ release modulates excitation-contraction coupling in rabbit ventricular myocytes. Am. J. Physiol. Heart Circ. Physiol. 2008, 294:H596-H604.
31. Chu I.M., Hengst L., Slingerland J.M. The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat. Rev. Cancer 2008, 8:253-267.
32. Murphy E., Freudenrich C.C., Lieberman M. Cellular magnesium and Na/Mg exchange in heart cells. Annu. Rev. Physiol. 1991, 53:273-287.
33. Saris N.E., Mervaala E., Karppanen H., Khawaja J.A., Lewenstam A. Magnesium: an update on physiological, clinical and analytical aspects. Clin. Chim. Acta 2000, 294:1-26.