Rabies virus glycoprotein and immune response pattern using recombinant protein or recombinant RNA viral vectors

Vaccine

Volumn 32, Issue 24, 2014, Pages 2829-2832

  Astray, Renato M ^a   Ventini, Daniella C ^a   Boldorini, Vera L L ^a   Silva, Fernanda G ^a   Rocca, Mayra P ^a   Pereira, Carlos A ^a  

^a INSTITUTO BUTANTAN   (Brazil)

Author keywords

Immune response; Protein; Rabies; RNA; Vaccine

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 2; RABIES VACCINE; RECOMBINANT PROTEIN; RECOMBINANT RABIES VIRUS GLYCOPROTEIN; RECOMBINANT RNA; RNA VACCINE; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS VACCINE; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DROSOPHILA MELANOGASTER; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMORAL IMMUNITY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RABIES; RABIES VIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA IMMUNIZATION; SEMLIKI FOREST ALPHAVIRUS; WESTERN BLOTTING;

IMMUNE RESPONSE; PROTEIN; RABIES; RNA; VACCINE;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CELL LINE; DROSOPHILA MELANOGASTER; GLYCOPROTEINS; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNOGLOBULIN G; INTERFERON-GAMMA; INTERLEUKIN-2; MICE; MICE, INBRED BALB C; RABIES; RABIES VACCINES; RABIES VIRUS; RECOMBINANT PROTEINS; RNA; VACCINES, SYNTHETIC; VIRAL ENVELOPE PROTEINS;

EID: 84899959976     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.02.029     Document Type: Article

References (16)

1. Josefsberg J.O., Buckland B. Vaccine process technology. Biotechnol Bioeng 2012, 109:1443-1460.
2. Li L., Saade F., Petrovsky N. The future of human DNA vaccines. J Biotechnol 2012, 162:171-182.
3. Ulmer J.B., Mason P.W., Geall A., Mandl C.W. RNA-based vaccines. Vaccine 2012, 30:4414-4418.
4. Rueckert C., Guzmán C.A. Vaccines. From empirical development to rational design. PLoS Pathog 2012, 8(11 (November)):e1003001. [Epub 8 November 2012]. 10.1371/journal.ppat.1003001.
5. Rappuoli R., Mandl C.W., Black S., De Gregorio E. Vaccines for the twenty-first century society. Nat Rev Immunol 2011, 11:865-872.
6. Quetglas J.I., et al. Alphavirus vectors for cancer therapy. Virus Res 2010, 153:179-196.
7. Moraes A.M., Jorge S.A.C., Astray R.M., Suazo C.A.T., Calderón Riquelmec C.E., Augusto E.F.P., et al. Drosophila melanogaster S2 cells for expression of heterologous genes: from gene cloning to bioprocess development. Biotechnol Adv 2012, 30:613-628.
8. Benmaamar R., Astray R.M., Wagner R., Pereira C.A. High-level expression of rabies virus glycoprotein with the RNA-based Semliki Forest Virus expression vector. J Biotechnol 2009, 139:283-290.
9. Lemos M.A.N., Santos A.S., Astray R.M., Pereira C.A., Jorge S.A.C. Rabies virus glycoprotein expression in Drosophila S2 cells. I. Design of expression/selection vectors, subpopulations selection and influence of sodium butyrate and culture medium on protein expression. J Biotechnol 2009, 143:103-110.
10. Ventini D.C., Astray R.M., Lemos M.A.N., Jorge S.A.C., Calderon C., Suazo C.A.T., Tonso A., Pereira C.A. Recombinant rabies virus glycoprotein synthesis in bioreactor by transfected Drosophila melanogaster S2 cells carrying a constitutive or an inducible promoter. J Biotechnol 2010, 146:169-172.
11. Astray R.M., Augusto E., Yokomizo A.Y., Pereira C.A. Analytical approach for extraction of recombinant membrane viral glycoprotein from stably transfected Drosophila melanogaster cells. Biotechnol J 2008, 3:98-103.
12. Astray R.M., Jorge S.A.C., Lemos M.A.N., Yokomizo A.Y., Boldorini V.L.L., Puglia A.L.P., et al. Kinetic studies of recombinant rabies virus glycoprotein (RVGP) cDNA transcription and mRNA translation in Drosophila melanogaster S2 cell populations. Cytotechnology 2013, 65:829-838.
13. Santos M.G., Jorge S.A.C., Brillet K., Pereira C.A. Improving heterologous protein expression in transfected Drosophila S2 cells as assessed by EGFP expression. Cytotechnology 2007, 54:15-24.
14. Frazzati-Gallina N., Paoli R.L., Mourão-Fuches R.M., Jorge S.A.C., Pereira C.A. Higher production of rabies virus in serum-free medium cell cultures on microcarriers. J Biotechnol 2001, 92:67-72.
15. Yokomizo A.Y., Jorge S.A.C., Astray R.M., Fernandes I., Ribeiro O.G., Horton D.S.P.Q., et al. Rabies virus glycoprotein expression in Drosophila S2 cells I. Functional recombinant protein in stable co-transfected cell line. Biotechnol J 2007, 2:102-109.
16. Rollier C.S., Reyes-Sandoval A., Cottingham M.G., Ewer K., Hill A.V.S. Viral vectors as vaccine platforms: deployment in sight. Curr Opin Immunol 2011, 23:377-382.