Amino acid profile index for early detection of endometrial cancer: Verification as a novel diagnostic marker

International Journal of Clinical Oncology

Volumn 19, Issue 2, 2014, Pages 364-372

  Ihata, Yutaka ^a   Miyagi, Etsuko ^a   Numazaki, Reiko ^a   Muramatsu, Takahiko ^b   Imaizumi, Akira ^b   Yamamoto, Hiroshi ^b   Yamakado, Minoru ^c   Okamoto, Naoyuki ^d   Hirahara, Fumiki ^a  

^a YOKOHAMA CITY UNIVERSITY HOSPITAL   (Japan)

^b AJINOMOTO CO INC   (Japan)

^c MITSUI MEMORIAL HOSPITAL   (Japan)

^d KANAGAWA CANCER CENTER   (Japan)

Author keywords

Endometrial cancer; Plasma amino acid profile; Tumor marker

Indexed keywords

AMINO ACID; ASPARAGINE; CA 125 ANTIGEN; HISTIDINE; ISOLEUCINE; LEUCINE; METHIONINE; ORNITHINE; PHENYLALANINE; PROLINE; SERINE; TRYPTOPHAN; TUMOR MARKER; VALINE; INDOLEAMINE 2,3 DIOXYGENASE;

ADENOMYOSIS; ADENOSQUAMOUS CARCINOMA; ADULT; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; BENIGN TUMOR; CANCER DIAGNOSIS; CANCER SCREENING; CENTRIFUGAL ANALYZER; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; EARLY CANCER; EARLY DIAGNOSIS; ELECTROSPRAY MASS SPECTROMETRY; ENDOMETRIOID CARCINOMA; ENDOMETRIUM BIOPSY; ENDOMETRIUM CANCER; ENDOMETRIUM CARCINOMA; ENDOMETRIUM CYST; FEMALE; FIBROMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LEIOMYOMA; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MUCINOUS CYST ADENOMA; MUCINOUS CYSTIC NEOPLASM; OVARY TERATOMA; PLASMA AMINO ACID PROFILE INDEX; POORLY DIFFERENTIATED CARCINOMA; PREDICTIVE VALUE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEROUS CYST ADENOMA; SQUAMOUS CELL CARCINOMA; VERY ELDERLY; AREA UNDER THE CURVE; BLOOD; ENDOMETRIAL NEOPLASMS; METABOLISM; MIDDLE AGED; PROCEDURES; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACIDS; AREA UNDER CURVE; CA-125 ANTIGEN; EARLY DETECTION OF CANCER; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; MIDDLE AGED; TUMOR MARKERS, BIOLOGICAL;

EID: 84899949945     PISSN: 13419625     EISSN: 14377772     Source Type: Journal    
DOI: 10.1007/s10147-013-0565-2     Document Type: Article

References (27)

1. Jemal A, Siegel R, Ward E et al (2009) Cancer statistics, 2009. CA Cancer J Clin 59:225-249
2. Gynecologic Cancer Committee (2009) Annual report of gynecologic cancer (in Japanese). Acta Obstet Gynaecol Jpn 61:2159-2197
3. Bast RC Jr, Feeney M, Lazarus H et al (1981) Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 68:1331-1337 (Pubitemid 12235035)
4. Niloff JM, Klug TL, Schaetzl E et al (1984) Elevation of serum CA125 in carcinomas of the fallopian tube, endometrium, and endocervix. Am J Obstet Gynecol 148:1057-1058 (Pubitemid 14136410)
5. Sood AK, Buller RE, Burger RA et al (1997) Value of preoperative CA 125 level in the management of uterine cancer and prediction of clinical outcome. Obstet Gynecol 90:441-447 (Pubitemid 27357939)
6. Dotters DJ (2000) Preoperative CA 125 in endometrial cancer: is it useful? Am J Obstet Gynecol 182:1328-1334
7. Fioretti P, Gadducci A, Ferdeghini M et al (1988) Preoperative evaluation of CA 125 and CA 19-9 serum levels in patients with ovarian masses. Eur J Gynaecol Oncol 9:291-294
8. Goksedef BP, Gorgen H, Baran SY et al (2011) Preoperative serum CA 125 level as a predictor for metastasis and survival in endometrioid endometrial cancer. J Obstet Gynaecol Can 33:844-850
9. Yoshida H, Mizukoshi T, Hirayama K et al (2007) Comprehensive analytical method for the determination of hydrophilic metabolites by high-performance liquid chromatography and mass spectrometry. J Agric Food Chem 55:551-560
10. Lee K, Hwang D, Yokoyama T et al (2004) Identification of optimal classification functions for biological sample and state discrimination from metabolic profiling data. Bioinformatics 20:959-969 (Pubitemid 38559739)
11. Norton JA, Gorschboth CM, Wesley RA et al (1985) Fasting plasma amino acid levels in cancer patients. Cancer (Phila) 56:1181-1186 (Pubitemid 15003505)
12. Naini AB, Dickerson JW, Brown MM (1988) Preoperative and postoperative levels of plasma protein and amino acid in esophageal and lung cancer patients. Cancer (Phila) 62:355-360
13. Cascino A, Muscaritoli M, Cangiano C et al (1995) Plasma amino acid imbalance in patients with lung and breast cancer. Anticancer Res 15:507-510
14. Kubota A, Meguid MM, Hitch DC (1992) Amino acid profiles correlate diagnostically with organ site in three kinds of malignant tumors. Cancer (Phila) 69:2343-2348
15. Okamoto N, Miyagi Y, Chiba A et al (2009) Diagnostic modeling with differences in plasma amino acid profiles between noncachectic colorectal/breast cancer patients and healthy individuals. Int J Med Med Sci 1:1-8
16. Peduzzi P, Concato J, Kemper E et al (1996) A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol 49:1373-1379 (Pubitemid 27028925)
17. R Development Core Team (2009) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna
18. Proenza AM, Oliver J, Palou A et al (2003) Breast and lung cancer are associated with a decrease in blood cell amino acid content. J Nutr Biochem 14:133-138 (Pubitemid 36542998)
19. Pisters PW, Pearlstone DB (1993) Protein and amino acid metabolism in cancer cachexia: investigative techniques and therapeutic interventions. Crit Rev Clin Lab Sci 30:223-272 (Pubitemid 23287832)
20. Lai HS, Lee JC, Lee PH et al (2005) Plasma free amino acid profile in cancer patients. Semin Cancer Biol 15:267-276
21. Maeda J, Higashiyama M, Imaizumi A et al (2010) Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study. BMC Cancer 10:690
22. Uyttenhove C, Pilotte L, Theate I et al (2003) Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med 9:1269-1274 (Pubitemid 37279849)
23. Mellor AL, Munn DH (2004) IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 4:762-774 (Pubitemid 39336293)
24. Suzuki Y, Suda T, Furuhashi K et al (2010) Increased serum kynurenine/tryptophan ratio correlates with disease progression in lung cancer. Lung Cancer 67:361-365
25. Vissers YL, Dejong CH, Luiking YC et al (2005) Plasma arginine concentrations are reduced in cancer patients: evidence for arginine deficiency? Am J Clin Nutr 81:1142-1146 (Pubitemid 41724957)
26. Deligdisch L, Holinka CF (1987) Endometrial carcinoma: two diseases? Cancer Detect Prev 10:237-246
27. Opolskiene G, Sladkevicius P, Valentin L (2011) Prediction of endometrial malignancy in women with postmenopausal bleeding and sonographic endometrial thickness ≥4.5 mm. Ultrasound Obstet Gynecol 37:232-240