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Volumn 142, Issue , 2014, Pages 62-67

Genomic and non-genomic actions of progestogens in the breast

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; DROSPIRENONE; ETONOGESTREL; GESTAGEN; GLUCOCORTICOID RECEPTOR; LEVONORGESTREL; MEDROXYPROGESTERONE ACETATE; MINERALOCORTICOID RECEPTOR; NORETHISTERONE ACETATE; PROGESTERONE; PROGESTERONE RECEPTOR A; PROGESTERONE RECEPTOR B; TRIMEGESTONE;

EID: 84899938577     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.08.011     Document Type: Review
Times cited : (37)

References (82)
  • 2
    • 84899974590 scopus 로고    scopus 로고
    • Breast cancer: prevention and control, World Health Organization
    • Breast cancer: prevention and control, World Health Organization. http://www.who.int/cancer/detection/breastcancer/en/index1.html.
  • 3
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women
    • Writing Group for the Women's Health Initiative Investigators
    • Writing Group for the Women's Health Initiative Investigators Risks and benefits of estrogen plus progestin in healthy postmenopausal women JAMA 288 2002 321 333
    • (2002) JAMA , vol.288 , pp. 321-333
  • 4
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone replacement therapy in the Million Women Study
    • Million Women Study Collaborators Breast cancer and hormone replacement therapy in the Million Women Study Lancet 362 2003 419 427
    • (2003) Lancet , vol.362 , pp. 419-427
  • 5
    • 36549076409 scopus 로고    scopus 로고
    • Unequal risks for breast cancer associated with different hormone replacement therapies: Results from the E3N cohort study
    • A. Fournier, F. Berrino, and F. Clavel-Chapelon Unequal risks for breast cancer associated with different hormone replacement therapies: results from the E3N cohort study Breast Cancer Res. Treat. 107 2008 103 111
    • (2008) Breast Cancer Res. Treat. , vol.107 , pp. 103-111
    • Fournier, A.1    Berrino, F.2    Clavel-Chapelon, F.3
  • 6
    • 1842867053 scopus 로고    scopus 로고
    • Effects of conjugated equine estrogen in postmenopausal women with hysterectomy
    • The Women's Health Initiative Steering Committee
    • The Women's Health Initiative Steering Committee Effects of conjugated equine estrogen in postmenopausal women with hysterectomy JAMA 291 2004 1701 1712
    • (2004) JAMA , vol.291 , pp. 1701-1712
  • 7
    • 0346366924 scopus 로고    scopus 로고
    • Progesterone-dependent regulation of female reproductive activity by two-distinct progesterone receptor isoforms
    • O.M. Conneely, B. Maulac-Jeticevic, and J.P. Lydon Progesterone-dependent regulation of female reproductive activity by two-distinct progesterone receptor isoforms Steroids 68 2003 771 778
    • (2003) Steroids , vol.68 , pp. 771-778
    • Conneely, O.M.1    Maulac-Jeticevic, B.2    Lydon, J.P.3
  • 8
    • 84876059228 scopus 로고    scopus 로고
    • Progestogens used in postmenopausal hormone therapy: Differences in their pharmacological properties, intracellular actions, and clinical effects
    • (first published ahead of print 13.12.12) 10.1210/er.2012-1008
    • F.Z. Stanczyk, J.P. Hapgood, S. Winer, and D.R. Mishell Jr. Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects Endocr. Rev. 2012 (first published ahead of print 13.12.12) 10.1210/er.2012-1008
    • (2012) Endocr. Rev.
    • Stanczyk, F.Z.1    Hapgood, J.P.2    Winer, S.3    Mishell, Jr.D.R.4
  • 10
    • 0026768322 scopus 로고
    • A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms
    • M.E. Meyer, C. Quirin-Stricker, T. Lerouge, M.T. Bocquel, and H. Gronemeyer A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms J. Biol. Chem. 267 1992 10882 10887
    • (1992) J. Biol. Chem. , vol.267 , pp. 10882-10887
    • Meyer, M.E.1    Quirin-Stricker, C.2    Lerouge, T.3    Bocquel, M.T.4    Gronemeyer, H.5
  • 11
    • 0028073682 scopus 로고
    • A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform
    • C.A. Sartorius, M.Y. Melville, A.R. Hovland, L. Tung, G.S. Takimoto, and K.B. Horwitz A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform Mol. Endocrinol. 8 1994 1347 1360
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1347-1360
    • Sartorius, C.A.1    Melville, M.Y.2    Hovland, A.R.3    Tung, L.4    Takimoto, G.S.5    Horwitz, K.B.6
  • 12
    • 0034622974 scopus 로고    scopus 로고
    • Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform
    • B. Mulac-Jericevic, R.A. Mullinax, F.J. DeMayo, J.P. Lydon, and O.M. Conneely Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform Science 289 2000 1751 1754
    • (2000) Science , vol.289 , pp. 1751-1754
    • Mulac-Jericevic, B.1    Mullinax, R.A.2    Demayo, F.J.3    Lydon, J.P.4    Conneely, O.M.5
  • 13
  • 14
    • 0031906819 scopus 로고    scopus 로고
    • Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands
    • G. Shyamala, X. Yang, G. Silberstein, M.H. Barcellos-Hoff, and E. Dale Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands Proc. Natl. Acad. Sci. U.S.A. 95 1998 696 701
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 696-701
    • Shyamala, G.1    Yang, X.2    Silberstein, G.3    Barcellos-Hoff, M.H.4    Dale, E.5
  • 15
    • 0034724165 scopus 로고    scopus 로고
    • Impact of progesterone receptor on cell-fate decisions during mammary gland development
    • G. Shyamala, X. Yang, R.D. Cardiff, and E. Dale Impact of progesterone receptor on cell-fate decisions during mammary gland development Proc. Natl. Acad. Sci. U.S.A. 97 2000 3044 3049
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 3044-3049
    • Shyamala, G.1    Yang, X.2    Cardiff, R.D.3    Dale, E.4
  • 16
    • 14844304709 scopus 로고    scopus 로고
    • Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology
    • B.M. Jacobsen, S.A. Schittone, J.K. Richer, and K.B. Horwitz Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology Mol. Endocrinol. 19 2005 574 587
    • (2005) Mol. Endocrinol. , vol.19 , pp. 574-587
    • Jacobsen, B.M.1    Schittone, S.A.2    Richer, J.K.3    Horwitz, K.B.4
  • 17
    • 0033305372 scopus 로고    scopus 로고
    • Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals
    • C.A. Lange, J.K. Richer, and K.B. Horwitz Hypothesis: progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals Mol. Endocrinol. 13 1999 829 836
    • (1999) Mol. Endocrinol. , vol.13 , pp. 829-836
    • Lange, C.A.1    Richer, J.K.2    Horwitz, K.B.3
  • 18
    • 0033673829 scopus 로고    scopus 로고
    • In vitro characterization of trimegestone: A new potent and selective progestin
    • Z. Zhang, S.G. Lundeen, Y. Zhu, J.M. Carver, and R.C. Winneker In vitro characterization of trimegestone: a new potent and selective progestin Steroids 65 2000 637 643
    • (2000) Steroids , vol.65 , pp. 637-643
    • Zhang, Z.1    Lundeen, S.G.2    Zhu, Y.3    Carver, J.M.4    Winneker, R.C.5
  • 21
    • 0018369315 scopus 로고
    • The use of medroxyprogesterone acetate to study progestin receptors in immature, pregnant, and adult rabbit uterus
    • P.D. Feil, and C.W. Bardin The use of medroxyprogesterone acetate to study progestin receptors in immature, pregnant, and adult rabbit uterus Adv. Exp. Med. Biol. 117 1979 241 254
    • (1979) Adv. Exp. Med. Biol. , vol.117 , pp. 241-254
    • Feil, P.D.1    Bardin, C.W.2
  • 22
    • 0029863026 scopus 로고    scopus 로고
    • Binding specificity of medroxyprogesterone acetate and proligestone for the progesterone and glucocorticoid receptor in the dog
    • P.J. Selman, J. Wolfswinkel, and J.A. Mol Binding specificity of medroxyprogesterone acetate and proligestone for the progesterone and glucocorticoid receptor in the dog Steroids 61 1996 133 137
    • (1996) Steroids , vol.61 , pp. 133-137
    • Selman, P.J.1    Wolfswinkel, J.2    Mol, J.A.3
  • 23
    • 0033740135 scopus 로고    scopus 로고
    • Influence of the substitution of 11-methylene, delta(15), and/or 18-methyl groups in norethisterone on receptor binding, transactivation assays and biological activities in animals
    • G.H. Deckers, W.G. Schoonen, and H.J. Kloosterboer Influence of the substitution of 11-methylene, delta(15), and/or 18-methyl groups in norethisterone on receptor binding, transactivation assays and biological activities in animals J. Steroid Biochem. Mol. Biol. 74 2000 83 92
    • (2000) J. Steroid Biochem. Mol. Biol. , vol.74 , pp. 83-92
    • Deckers, G.H.1    Schoonen, W.G.2    Kloosterboer, H.J.3
  • 25
    • 0016665475 scopus 로고
    • Progesteronebinding proteins: In vitro binding and biological activity of different steroidal ligands
    • K. Kontula, O. Janne, R. Vihko, E. de Jager, J. de Visser, and F. Zeelen Progesteronebinding proteins: in vitro binding and biological activity of different steroidal ligands Acta Endocrinol. 78 1975 574 592
    • (1975) Acta Endocrinol. , vol.78 , pp. 574-592
    • Kontula, K.1    Janne, O.2    Vihko, R.3    De Jager, E.4    De Visser, J.5    Zeelen, F.6
  • 26
    • 0030273673 scopus 로고    scopus 로고
    • The novel progestin drospirenone and its natural counterpart progesterone: Biochemical profile and antiandrogenic potential
    • U. Fuhrmann, R. Krattenmacher, E.P. Slater, and K.H. Fritzemeier The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential Contraception 54 1996 243 251
    • (1996) Contraception , vol.54 , pp. 243-251
    • Fuhrmann, U.1    Krattenmacher, R.2    Slater, E.P.3    Fritzemeier, K.H.4
  • 27
    • 0033833321 scopus 로고    scopus 로고
    • Drospirenone: Pharmacology and pharmacokinetics of a unique progestogen
    • R. Krattenmacher Drospirenone: pharmacology and pharmacokinetics of a unique progestogen Contraception 62 2000 29 38
    • (2000) Contraception , vol.62 , pp. 29-38
    • Krattenmacher, R.1
  • 28
    • 0023802958 scopus 로고
    • Selectivity in progesterone and androgen receptor binding of progestagens used in oral contraceptives
    • H.J. Kloosterboer, C.A. Vonk-Noordegraaf, and E.W. Turpijn Selectivity in progesterone and androgen receptor binding of progestagens used in oral contraceptives Contraception 38 1988 325 332
    • (1988) Contraception , vol.38 , pp. 325-332
    • Kloosterboer, H.J.1    Vonk-Noordegraaf, C.A.2    Turpijn, E.W.3
  • 29
    • 0031916316 scopus 로고    scopus 로고
    • Human progesterone receptor A and B isoforms in CHO cells. II. Comparison of binding, transactivation and ed50 values of several synthetic (anti)progestagens in vitro in CHO and MCF-7 cells and in vivo in rabbits and rats
    • W.G.E.J. Schoonen, R. Dijkema, R.J.H. de Ries, J.L. Wagenaars, J.W.H. Joosten, M.E. de Gooyer, G.H. Deckers, and H.J. Kloosterboer Human progesterone receptor A and B isoforms in CHO cells. II. Comparison of binding, transactivation and ed50 values of several synthetic (anti)progestagens in vitro in CHO and MCF-7 cells and in vivo in rabbits and rats J. Steroid Biochem. Mol. Biol. 64 1998 157 170
    • (1998) J. Steroid Biochem. Mol. Biol. , vol.64 , pp. 157-170
    • Schoonen, W.G.E.J.1    Dijkema, R.2    De Ries, R.J.H.3    Wagenaars, J.L.4    Joosten, J.W.H.5    De Gooyer, M.E.6    Deckers, G.H.7    Kloosterboer, H.J.8
  • 30
    • 34447644893 scopus 로고    scopus 로고
    • The progestational and androgenic properties of medroxyprogesterone acetate: Gene regulatory overlap with dihydrotestosterone in breast cancer cells
    • R. Ghatge, B. Jacobsen, S. Schittone, and K. Horwitz The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells Breast Cancer Res. 7 2005 R1036 R1050
    • (2005) Breast Cancer Res. , vol.7
    • Ghatge, R.1    Jacobsen, B.2    Schittone, S.3    Horwitz, K.4
  • 32
    • 84860342733 scopus 로고    scopus 로고
    • Multiple nuclear receptor signalling pathways mediate the actions of synthetic progestins in target cells
    • N.L. Moore, T.E. Hickey, L.M. Butler, and W.D. Tilley Multiple nuclear receptor signalling pathways mediate the actions of synthetic progestins in target cells Mol. Cell. Endocrinol. 397 2012 60 70
    • (2012) Mol. Cell. Endocrinol. , vol.397 , pp. 60-70
    • Moore, N.L.1    Hickey, T.E.2    Butler, L.M.3    Tilley, W.D.4
  • 33
    • 0019074917 scopus 로고
    • Multiple hormone interactions in the developmental biology of the mammary gland
    • Y.J. Topper, and C.S. Freeman Multiple hormone interactions in the developmental biology of the mammary gland Physiol. Rev. 60 1980 1049 1106
    • (1980) Physiol. Rev. , vol.60 , pp. 1049-1106
    • Topper, Y.J.1    Freeman, C.S.2
  • 34
    • 0025293539 scopus 로고
    • Progestin regulation of cellular proliferation
    • C.L. Clarke, and R.L. Sutherland Progestin regulation of cellular proliferation Endocr. Rev. 11 1990 266 301
    • (1990) Endocr. Rev. , vol.11 , pp. 266-301
    • Clarke, C.L.1    Sutherland, R.L.2
  • 35
    • 0021193269 scopus 로고
    • The effect of estrogen, progesterone, thyroxine, and human placental lactogen on DNA synthesis of human breast ductal epithelium maintained in athymic nude mice
    • M.J. McManus, and C.W.C.W. Welsch The effect of estrogen, progesterone, thyroxine, and human placental lactogen on DNA synthesis of human breast ductal epithelium maintained in athymic nude mice Cancer 54 1984 1920 1927
    • (1984) Cancer , vol.54 , pp. 1920-1927
    • McManus, M.J.1    Welsch, C.W.C.W.2
  • 36
    • 0028796304 scopus 로고
    • The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone
    • I.J. Laidlaw, R.B. Clarke, A. Howell, A.W.M.C. Owen, C.S. Potten, and E. Anderson The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone Endocrinology 136 1995 164 171
    • (1995) Endocrinology , vol.136 , pp. 164-171
    • Laidlaw, I.J.1    Clarke, R.B.2    Howell, A.3    Owen, A.W.M.C.4    Potten, C.S.5    Anderson, E.6
  • 37
    • 0022973708 scopus 로고
    • Progestin effect on cell proliferation and 17b-hydroxysteroid dehydrogenase activity in normal human breast cells in culture
    • A. Gompel, C. Malet, P. Spritzer, J.-P. Lalardrie, F. Kutten, and P. Mauvais-Jarvis Progestin effect on cell proliferation and 17b-hydroxysteroid dehydrogenase activity in normal human breast cells in culture J. Clin. Endocrinol. Metab. 63 1986 1174 1180
    • (1986) J. Clin. Endocrinol. Metab. , vol.63 , pp. 1174-1180
    • Gompel, A.1    Malet, C.2    Spritzer, P.3    Lalardrie, J.-P.4    Kutten, F.5    Mauvais-Jarvis, P.6
  • 38
    • 0026770477 scopus 로고
    • Effects of progestins on the proliferation of estrogen-dependent human breast cancer cells under growth factor-defined conditions
    • B. van der Burg, E. Kalkhoven, L. Isbrücker, and S.W. de Laat Effects of progestins on the proliferation of estrogen-dependent human breast cancer cells under growth factor-defined conditions J. Steroid Biochem. Mol. Biol. 42 1992 457 465
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.42 , pp. 457-465
    • Van Der Burg, B.1    Kalkhoven, E.2    Isbrücker, L.3    De Laat, S.W.4
  • 39
    • 0027196251 scopus 로고
    • Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism
    • W.H. Catherino, M.H. Jeng, and V.C. Jordan Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism Br. J. Cancer 67 1993 945 952
    • (1993) Br. J. Cancer , vol.67 , pp. 945-952
    • Catherino, W.H.1    Jeng, M.H.2    Jordan, V.C.3
  • 40
    • 0029417037 scopus 로고
    • Effects of two classes of progestins, Pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: 1.MCF-7 cell lines
    • W.G.E.J. Schoonen, J.W.H. Joosten, and H.J. Kloosterboer Effects of two classes of progestins, Pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: 1.MCF-7 cell lines J. Steroid Biochem. Mol. Biol. 55 1995 423 437
    • (1995) J. Steroid Biochem. Mol. Biol. , vol.55 , pp. 423-437
    • Schoonen, W.G.E.J.1    Joosten, J.W.H.2    Kloosterboer, H.J.3
  • 41
    • 0029553143 scopus 로고
    • Effect of progestin treatment on estradiol- and growth factor-stimulated breast cancer cell lines
    • V. Cappelletti, P. Miodini, L. Fioravanti, and G. DiFronzo Effect of progestin treatment on estradiol- and growth factor-stimulated breast cancer cell lines Anticancer Res. 15 1995 2551 2556
    • (1995) Anticancer Res. , vol.15 , pp. 2551-2556
    • Cappelletti, V.1    Miodini, P.2    Fioravanti, L.3    Difronzo, G.4
  • 42
    • 40849121420 scopus 로고    scopus 로고
    • The effect of progesterone, testosterone and synthetic progestogens on growth factor- and estradiol-treated human cancerous and benign breast cells
    • E.A. Krämer, H. Seeger, B. Krämer, D. Wallwiener, and A.O. Mueck The effect of progesterone, testosterone and synthetic progestogens on growth factor- and estradiol-treated human cancerous and benign breast cells Eur. J. Obstet. Gynecol. Reprod. 27 2006 139 141
    • (2006) Eur. J. Obstet. Gynecol. Reprod. , vol.27 , pp. 139-141
    • Krämer, E.A.1    Seeger, H.2    Krämer, B.3    Wallwiener, D.4    Mueck, A.O.5
  • 43
    • 0022346545 scopus 로고
    • Effects of interaction between estradiol-17 beta and progesterone on the proliferation of cloned breast tumor cells (MCF-7 and T47D)
    • R.W. Schatz, A.M. Soto, and C. Sonnenschein Effects of interaction between estradiol-17 beta and progesterone on the proliferation of cloned breast tumor cells (MCF-7 and T47D) J. Cell Physiol. 124 1985 386 390
    • (1985) J. Cell Physiol. , vol.124 , pp. 386-390
    • Schatz, R.W.1    Soto, A.M.2    Sonnenschein, C.3
  • 44
    • 0026483203 scopus 로고
    • Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation
    • M.H. Jeng, C.J. Parker, and V.C. Jordan Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation Cancer Res. 52 1992 6539 6546
    • (1992) Cancer Res. , vol.52 , pp. 6539-6546
    • Jeng, M.H.1    Parker, C.J.2    Jordan, V.C.3
  • 45
    • 0035206291 scopus 로고    scopus 로고
    • The effect of medroxyprogesterone acetate and norethisterone on the estradiol stimulated proliferation in MCF-7 cells: Comparison of continuous combined versus sequential combined estradiol/progestin treatment
    • C. Lippert, H. Seeger, D. Wallwiener, and A.O. Mueck The effect of medroxyprogesterone acetate and norethisterone on the estradiol stimulated proliferation in MCF-7 cells: comparison of continuous combined versus sequential combined estradiol/progestin treatment Eur. J. Gynaecol. Oncol. 22 2001 331 335
    • (2001) Eur. J. Gynaecol. Oncol. , vol.22 , pp. 331-335
    • Lippert, C.1    Seeger, H.2    Wallwiener, D.3    Mueck, A.O.4
  • 47
    • 0034014355 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis
    • E.K. Lobenhofer, G. Huper, J.D. Iglehart, and J.R. Marks Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis Cell Growth Differ. 11 2000 99 110
    • (2000) Cell Growth Differ. , vol.11 , pp. 99-110
    • Lobenhofer, E.K.1    Huper, G.2    Iglehart, J.D.3    Marks, J.R.4
  • 48
    • 0036721523 scopus 로고    scopus 로고
    • Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol
    • W. Yue, J.-P. Wang, M. Conaway, S. Masamura, Y. Li, and R. Santen Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol Endocrinology 143 2002 3221 3229
    • (2002) Endocrinology , vol.143 , pp. 3221-3229
    • Yue, W.1    Wang, J.-P.2    Conaway, M.3    Masamura, S.4    Li, Y.5    Santen, R.6
  • 49
    • 8344251694 scopus 로고    scopus 로고
    • Mitogenic activity of estrogens in human breast cancer cells does not rely on direct induction of mitogen-activated protein kinase/extracellularly regulated kinase or phosphatidylinositol 3-kinase
    • A.M. Gaben, C. Saucier, M. Bedin, G. Redeuilh, and J. Mester Mitogenic activity of estrogens in human breast cancer cells does not rely on direct induction of mitogen-activated protein kinase/extracellularly regulated kinase or phosphatidylinositol 3-kinase Mol. Endocrinol. 18 2004 2700 2713
    • (2004) Mol. Endocrinol. , vol.18 , pp. 2700-2713
    • Gaben, A.M.1    Saucier, C.2    Bedin, M.3    Redeuilh, G.4    Mester, J.5
  • 50
    • 0032553304 scopus 로고    scopus 로고
    • Convergence of progesterone and epidermal growth factor signalling in breast cancer
    • C.A. Lange, J.K. Richer, T. Shen, and K.B. Horwtiz Convergence of progesterone and epidermal growth factor signalling in breast cancer J. Biol. Chem. 273 1998 31308 31316
    • (1998) J. Biol. Chem. , vol.273 , pp. 31308-31316
    • Lange, C.A.1    Richer, J.K.2    Shen, T.3    Horwtiz, K.B.4
  • 51
    • 0142151083 scopus 로고    scopus 로고
    • Overexpression of wild-type p53 gene renders MCF-7 breast cancer cells more sensitive to the antiproliferative effect of progesterone
    • M. Alkhalaf, and A.M. El-Mowafy Overexpression of wild-type p53 gene renders MCF-7 breast cancer cells more sensitive to the antiproliferative effect of progesterone J. Endocrinol. 179 2003 55 62
    • (2003) J. Endocrinol. , vol.179 , pp. 55-62
    • Alkhalaf, M.1    El-Mowafy, A.M.2
  • 53
    • 0032005986 scopus 로고    scopus 로고
    • Progestin regulation of vascular endothelial growth factor in human breast cancer cells
    • S.M. Hyder, L. Murthy, and G.M. Stancel Progestin regulation of vascular endothelial growth factor in human breast cancer cells Cancer Res. 58 1998 392 395
    • (1998) Cancer Res. , vol.58 , pp. 392-395
    • Hyder, S.M.1    Murthy, L.2    Stancel, G.M.3
  • 54
    • 0017354142 scopus 로고
    • Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells
    • R.J. Pietras, and C.M. Szego Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells Nature 265 1977 69 72
    • (1977) Nature , vol.265 , pp. 69-72
    • Pietras, R.J.1    Szego, C.M.2
  • 55
    • 0028290639 scopus 로고
    • Androgens increase intracellular calcium concentration and inositol 1,4,5-trisphosphate and diacylglycerol formation via a pertussis toxin-sensitive G-protein
    • M. Lieberherr, and B. Grosse Androgens increase intracellular calcium concentration and inositol 1,4,5-trisphosphate and diacylglycerol formation via a pertussis toxin-sensitive G-protein J. Biol. Chem. 269 1994 7217 7223
    • (1994) J. Biol. Chem. , vol.269 , pp. 7217-7223
    • Lieberherr, M.1    Grosse, B.2
  • 56
    • 0037119394 scopus 로고    scopus 로고
    • Nongenomic testosterone calcium signaling. Genotropic actions in androgen receptor-free macrophages
    • Z. Guo, W.P. Benten, J. Krucken, and F. Wunderlich Nongenomic testosterone calcium signaling. Genotropic actions in androgen receptor-free macrophages J. Biol. Chem. 277 2002 29600 29607
    • (2002) J. Biol. Chem. , vol.277 , pp. 29600-29607
    • Guo, Z.1    Benten, W.P.2    Krucken, J.3    Wunderlich, F.4
  • 58
    • 0036717596 scopus 로고    scopus 로고
    • The human prostate cancer cell line LNCaP bears functional membrane testosterone receptors that increase PSA secretion and modify actin cytoskeleton
    • M. Kampa, E.A. Papakonstanti, A. Hatzoglou, E.N. Stathopoulos, C. Stournaras, and E. Castanas The human prostate cancer cell line LNCaP bears functional membrane testosterone receptors that increase PSA secretion and modify actin cytoskeleton FASEB J. 16 2002 1429 1431
    • (2002) FASEB J. , vol.16 , pp. 1429-1431
    • Kampa, M.1    Papakonstanti, E.A.2    Hatzoglou, A.3    Stathopoulos, E.N.4    Stournaras, C.5    Castanas, E.6
  • 59
    • 0036235678 scopus 로고    scopus 로고
    • Synthesis and evaluation of the cardiovascular effects of two, membrane impermeant, macromolecular complexes of dextran-testosterone
    • L. Figueroa-Valverde, H. Luna, C. Castillo-Henkel, O. Munoz-Garcia, T. Morato-Cartagena, and G. Ceballos-Reyes Synthesis and evaluation of the cardiovascular effects of two, membrane impermeant, macromolecular complexes of dextran-testosterone Steroids 67 2002 611 619
    • (2002) Steroids , vol.67 , pp. 611-619
    • Figueroa-Valverde, L.1    Luna, H.2    Castillo-Henkel, C.3    Munoz-Garcia, O.4    Morato-Cartagena, T.5    Ceballos-Reyes, G.6
  • 60
    • 0027313213 scopus 로고
    • Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm
    • J. Tesarik, J. Moos, and C. Mendoza Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm Endocrinology 133 1993 328 335
    • (1993) Endocrinology , vol.133 , pp. 328-335
    • Tesarik, J.1    Moos, J.2    Mendoza, C.3
  • 61
    • 0033804552 scopus 로고    scopus 로고
    • Membrane signalling and progesterone in female and male osteoblasts. I. Involvement of intracellular Ca(2+), inositol trisphosphate, and diacylglycerol, but not cAMP
    • B. Grosse, M. Kachkache, V. Le Mellay, and M. Lieberherr Membrane signalling and progesterone in female and male osteoblasts. I. Involvement of intracellular Ca(2+), inositol trisphosphate, and diacylglycerol, but not cAMP J. Cell. Biochem. 79 2000 334 345
    • (2000) J. Cell. Biochem. , vol.79 , pp. 334-345
    • Grosse, B.1    Kachkache, M.2    Le Mellay, V.3    Lieberherr, M.4
  • 62
    • 0030011373 scopus 로고    scopus 로고
    • Progesterone triggers rapid transmembrane calcium influx and/or calcium mobilization from endoplasmic reticulum, via a pertussisinsensitive G-protein in granulosa cells in relation to luteinization process
    • V. Machelon, F. Nome, B. Grosse, and M. Lieberherr Progesterone triggers rapid transmembrane calcium influx and/or calcium mobilization from endoplasmic reticulum, via a pertussisinsensitive G-protein in granulosa cells in relation to luteinization process J. Cell. Biochem. 61 1996 619 628
    • (1996) J. Cell. Biochem. , vol.61 , pp. 619-628
    • Machelon, V.1    Nome, F.2    Grosse, B.3    Lieberherr, M.4
  • 63
    • 0035813093 scopus 로고    scopus 로고
    • The classical progesterone receptor associates with p42 MAPK and is involved in phosphatidylinositol 3-kinase signaling in Xenopus oocytes
    • C.P. Bagowski, J.W. Myers, and J.E. Ferrell The classical progesterone receptor associates with p42 MAPK and is involved in phosphatidylinositol 3-kinase signaling in Xenopus oocytes J. Biol. Chem. 276 2001 37708 37714
    • (2001) J. Biol. Chem. , vol.276 , pp. 37708-37714
    • Bagowski, C.P.1    Myers, J.W.2    Ferrell, J.E.3
  • 64
    • 0344885580 scopus 로고    scopus 로고
    • Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor
    • Y. Zhu, J. Bond, and P. Thomas Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor Proc. Natl. Acad. Sci. U.S.A. 100 2003 2237 2242
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 2237-2242
    • Zhu, Y.1    Bond, J.2    Thomas, P.3
  • 65
    • 0344885581 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes
    • Y. Zhu, C.D. Rice, Y. Pang, M. Pace, and P. Thomas Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes Proc. Natl. Acad. Sci. U.S.A. 100 2003 2231 2236
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 2231-2236
    • Zhu, Y.1    Rice, C.D.2    Pang, Y.3    Pace, M.4    Thomas, P.5
  • 66
    • 0031871382 scopus 로고    scopus 로고
    • Cloning and tissue expression of two putative steroid membrane receptors
    • D. Gerdes, M. Wehling, B. Leube, and E. Falkenstein Cloning and tissue expression of two putative steroid membrane receptors Biol Chem. 379 1998 907 911
    • (1998) Biol Chem. , vol.379 , pp. 907-911
    • Gerdes, D.1    Wehling, M.2    Leube, B.3    Falkenstein, E.4
  • 67
    • 34547668765 scopus 로고    scopus 로고
    • Progesterone receptor membrane component 1: An integrative review
    • M.A.M.A. Cahill Progesterone receptor membrane component 1: an integrative review J. Steroid Biochem. Mol. Biol. 105 2007 16 36
    • (2007) J. Steroid Biochem. Mol. Biol. , vol.105 , pp. 16-36
    • Cahill, M.A.M.A.1
  • 68
    • 33845483366 scopus 로고    scopus 로고
    • Progesterone regulation of human granulosa/luteal cell viability by an RU486-independent mechanism
    • L. Engmann, R. Losel, M. Wehling, and J.J. Peluso Progesterone regulation of human granulosa/luteal cell viability by an RU486-independent mechanism J. Clin. Endocrinol. Metab. 91 2006 4962 4968
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 4962-4968
    • Engmann, L.1    Losel, R.2    Wehling, M.3    Peluso, J.J.4
  • 69
    • 13944252507 scopus 로고    scopus 로고
    • Classic and non-classic progesterone receptors are both expressed in human spermatozoa
    • R. Losel, S. Breiter, M. Seyfert, M. Wehling, and E. Falkenstein Classic and non-classic progesterone receptors are both expressed in human spermatozoa Horm. Metab. Res. 37 2005 10 14
    • (2005) Horm. Metab. Res. , vol.37 , pp. 10-14
    • Losel, R.1    Breiter, S.2    Seyfert, M.3    Wehling, M.4    Falkenstein, E.5
  • 70
    • 22844440963 scopus 로고    scopus 로고
    • Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors
    • G. Crudden, R. Loesel, and R.J. Craven Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors Tumour Biol. 26 2005 142 146
    • (2005) Tumour Biol. , vol.26 , pp. 142-146
    • Crudden, G.1    Loesel, R.2    Craven, R.J.3
  • 71
    • 84876397824 scopus 로고    scopus 로고
    • Expression of progesterone receptor membrane component-1 is associated with the malignant phenotypes of breast cancer
    • S.F. Ji, A.G. Wu, and H.F. Yang Expression of progesterone receptor membrane component-1 is associated with the malignant phenotypes of breast cancer Nan Fang Yi Ke Da Xue Xue Bao 32 2012 635 638
    • (2012) Nan Fang Yi Ke da Xue Xue Bao , vol.32 , pp. 635-638
    • Ji, S.F.1    Wu, A.G.2    Yang, H.F.3
  • 74
    • 70350322692 scopus 로고    scopus 로고
    • Progesterone receptor membrane component-1 regulates the development and Cisplatin sensitivity of human ovarian tumors in athymic nude mice
    • J.J. Peluso, A. Gawkowska, X. Liu, T. Shioda, and J.K. Pru Progesterone receptor membrane component-1 regulates the development and Cisplatin sensitivity of human ovarian tumors in athymic nude mice Endocrinology 150 2009 4846 4854
    • (2009) Endocrinology , vol.150 , pp. 4846-4854
    • Peluso, J.J.1    Gawkowska, A.2    Liu, X.3    Shioda, T.4    Pru, J.K.5
  • 75
    • 34447503431 scopus 로고    scopus 로고
    • Membrane-initiated effects of progesterone on calcium dependent signaling and activation of VEGF gene expression in retinal glial cells
    • M. Swiatek-De Lange, A. Stampfl, S.M. Hauck, H. Zischka, C.J. Gloeckner, C.A. Deeg, and M.M. Ueffing Membrane-initiated effects of progesterone on calcium dependent signaling and activation of VEGF gene expression in retinal glial cells Glia 55 2007 1061 1073
    • (2007) Glia , vol.55 , pp. 1061-1073
    • Swiatek-De Lange, M.1    Stampfl, A.2    Hauck, S.M.3    Zischka, H.4    Gloeckner, C.J.5    Deeg, C.A.6    Ueffing, M.M.7
  • 76
    • 85012188705 scopus 로고    scopus 로고
    • New insight on a possible mechanism of progestogens in terms of breast cancer risk
    • H. Neubauer, R. Chen, and H. Schneck New insight on a possible mechanism of progestogens in terms of breast cancer risk Horm. Mol. Biol. Clin. Invest. 6 2011 185 192
    • (2011) Horm. Mol. Biol. Clin. Invest. , vol.6 , pp. 185-192
    • Neubauer, H.1    Chen, R.2    Schneck, H.3
  • 78
    • 84867540206 scopus 로고    scopus 로고
    • Nomegestrol acetate sequentially or continuously combined to estradiol did not negatively affect membrane-receptor associated progestogenic effects in human breast cancer cells
    • X. Ruan, H. Schneck, S. Schultz, T. Fehm, M.A. Cahill, H. Seeger, R. Chen, Q. Yu, A.O. Mueck, and H. Neubauer Nomegestrol acetate sequentially or continuously combined to estradiol did not negatively affect membrane-receptor associated progestogenic effects in human breast cancer cells Gynecol. Endocrinol. 28 2012 863 866
    • (2012) Gynecol. Endocrinol. , vol.28 , pp. 863-866
    • Ruan, X.1    Schneck, H.2    Schultz, S.3    Fehm, T.4    Cahill, M.A.5    Seeger, H.6    Chen, R.7    Yu, Q.8    Mueck, A.O.9    Neubauer, H.10
  • 79
    • 57749085501 scopus 로고    scopus 로고
    • PGRMC1 (progesterone receptor membrane component 1): A targetable protein with multiple functions in steroid signaling. P450 activation and drug binding
    • H.J. Rohe, I.S. Ahmed, K.E. Twist, and R.J. Craven PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling. P450 activation and drug binding Pharmacol. Ther. 121 January (1) 2009 14 19
    • (2009) Pharmacol. Ther. , vol.121 , Issue.JANUARY 1 , pp. 14-19
    • Rohe, H.J.1    Ahmed, I.S.2    Twist, K.E.3    Craven, R.J.4
  • 80
    • 84877085705 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor 1 RNA-binding protein interacts with progesterone receptor membrane component 1 to regulate progesterone's ability to maintain the viability of spontaneously immortalized granulosa cells and rat granulosa cells
    • 10.1095/biolreprod.112.103036 (Print 2013 January)
    • J.J. Peluso, A. Yuan, X. Liu, and V. Lodde Plasminogen activator inhibitor 1 RNA-binding protein interacts with progesterone receptor membrane component 1 to regulate progesterone's ability to maintain the viability of spontaneously immortalized granulosa cells and rat granulosa cells Biol. Reprod. 88 January (1) 2013 20 10.1095/biolreprod.112.103036 (Print 2013 January)
    • (2013) Biol. Reprod. , vol.88 , Issue.JANUARY 1 , pp. 20
    • Peluso, J.J.1    Yuan, A.2    Liu, X.3    Lodde, V.4
  • 81
    • 0028258441 scopus 로고
    • ®: A randomised, single-blind, triple cross-over bioavailability study in menopausal women
    • ®: a randomised, single-blind, triple cross-over bioavailability study in menopausal women Maturitas 18 1994 229 238
    • (1994) Maturitas , vol.18 , pp. 229-238
    • Svensson, L.O.1    Johnson, S.H.2    Olsson, S.E.3
  • 82
    • 0018247177 scopus 로고
    • A radioimmunoassay for norethindrone (NET): Measurement of serum net concentrations following ingestion of NET-containing oral contraceptive steroids
    • F.Z. Stanczyk, P.F. Brenner, D.R. Mishell, A. Ortiz, E.K.E. Gentzschein, and Goebelsmann U: A radioimmunoassay for norethindrone (NET): measurement of serum net concentrations following ingestion of NET-containing oral contraceptive steroids Contraception 18 1978 615 633
    • (1978) Contraception , vol.18 , pp. 615-633
    • Stanczyk, F.Z.1    Brenner, P.F.2    Mishell, D.R.3    Ortiz, A.4    Gentzschein, E.K.E.5    Goebelsmann, U.6


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