The clinical relevance of voltage gated potassium channel (VGKC)-complex antibodies: The story is still unfolding

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 85, Issue 6, 2014, Pages 596-

  Park, Susanna B ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CONTACTIN ASSOCIATED PROTEIN 2; LEUCINE RICH GLIOMA INACTIVATED 1; MEMBRANE ANTIGEN; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL COMPLEX ANTIBODY;

ANTIBODY TITER; AUTOIMMUNITY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; EPILEPSY; HUMAN; IMMUNOTHERAPY; MENTAL DISEASE; NOTE; PAIN; PARANEOPLASTIC NEUROPATHY; PATHOGENICITY; PRIORITY JOURNAL; TREATMENT RESPONSE;

CLINICAL NEUROLOGY; NEUROIMMUNOLOGY;

ANTIBODIES; FEMALE; HUMANS; LIMBIC ENCEPHALITIS; MALE; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 84899931610     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2013-305811     Document Type: Note

References (4)

1. Irani SR, Alexander S, Waters P, et al. Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia. Brain 2010;139:2734-48.
2. Lai M, Huijbers MG, Lancaster E, et al. Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series. Lancet Neurol 2010;9:776-85.
3. Paterson RW, Zandi MS, Armstrong R, et al. Clinical relevance of positive voltage-gated potassium channel (VGKC)-complex antibodies: experience from a tertiary referral centre. J Neurol Neurosurg Psychiatry 2014;85:625-30.
4. Klein CJ, Lennon VA, Aston PA, et al. Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping. JAMA Neurol 2013;70:229-34.