Separations by gradient elution: Why are steep gradient profiles distorted and what is their impact on resolution in reversed-phase liquid chromatography

Journal of Chromatography A

Volumn 1344, Issue , 2014, Pages 66-75

  Gritti, Fabrice ^a   Guiochon, Georges ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Acetonitrile; Distorted gradients; Excess adsorption isotherms; Gradient chromatography; Methanol

Indexed keywords

ACETONITRILE; ADSORPTION ISOTHERMS; CHROMATOGRAPHIC ANALYSIS; LIQUID CHROMATOGRAPHY;

BASELINE RESOLUTION; CONCENTRATION PROFILES; DISTORTED GRADIENTS; EXCESS ADSORPTION ISOTHERMS; GRADIENT CHROMATOGRAPHY; REVERSED-PHASE LIQUID CHROMATOGRAPHY; SECOND ORDER DERIVATIVES;

METHANOL;

ACETONITRILE; METHANOL; ORGANIC SOLVENT;

ADSORPTION; ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELUTION; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; VALIDATION PROCESS;

ACETONITRILE; DISTORTED GRADIENTS; EXCESS ADSORPTION ISOTHERMS; GRADIENT CHROMATOGRAPHY; METHANOL; SYMMETRY-C(18);

ACETONITRILES; ADSORPTION; CHROMATOGRAPHY, REVERSE-PHASE; METHANOL; SOLUTIONS; WATER;

EID: 84899921652     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.04.010     Document Type: Article

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