Lack of association between CALHM1 p.P86L variation and Alzheimer's disease in the Han Chinese population

Neurobiology of Aging

Volumn 35, Issue 8, 2014, Pages 1956.e13-1956.e14

  Tao, Qing Qing ^a   Sun, Yi Min ^a   Liu, Zhi Jun ^a   Yang, Ping ^a   Li, Hong Lei ^a   Lu, Shen Ji ^a   Wu, Zhi Ying ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Association; CALHM1; Chinese

Indexed keywords

LEUCINE; MEMBRANE PROTEIN; PROLINE; PROTEIN CALHM1; UNCLASSIFIED DRUG; CALCIUM CHANNEL; CALHM1 PROTEIN, HUMAN;

AGE DISTRIBUTION; ALZHEIMER DISEASE; ARTICLE; ASIAN; CALHM1 GENE; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; POPULATION RESEARCH; PRIORITY JOURNAL; SEX DIFFERENCE; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; META ANALYSIS (TOPIC);

ALZHEIMER DISEASE; ASIAN CONTINENTAL ANCESTRY GROUP; CALCIUM CHANNELS; CASE-CONTROL STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; META-ANALYSIS AS TOPIC;

EID: 84899916752     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.02.013     Document Type: Article

References (10)

1. Beecham G.W., Schnetz-Boutaud N., Haines J.L., Pericak-Vance M.A. CALHM1 polymorphism is not associated with late-onset Alzheimer disease. Ann. Hum. Genet. 2009, 73(Pt 3):379-381.
2. Bertram L., Schjeide B.M., Hooli B., Mullin K., Hiltunen M., Soininen H., Ingelsson M., Lannfelt L., Blacker D., Tanzi R.E. No association betweenCALHM1 and Alzheimer's disease risk. Cell 2008, 135:993-994. author reply 4-6.
3. Boada M., Antunez C., Lopez-Arrieta J., Galan J.J., Moron F.J., Hernandez I., Marin J., Martinez-Lage P., Alegret M., Carrasco J.M., Moreno C., Real L.M., Gonzalez-Perez A., Tarraga L., Ruiz A. CALHM1 P86L polymorphism is associated with late-onset Alzheimer's disease in a recessive model. J.Alzheimers Dis. 2010, 20:247-251.
4. Cui P.J., Zheng L., Cao L., Wang Y., Deng Y.L., Wang G., Xu W., Tang H.D., Ma J.F., Zhang T., Ding J.Q., Cheng Q., Chen S.D. CALHM1 P86L polymorphism is a risk factor for Alzheimer's disease in the Chinese population. J.Alzheimers Dis. 2010, 19:31-35.
5. Dreses-Werringloer U., Lambert J.C., Vingtdeux V., Zhao H., Vais H., Siebert A., Jain A., Koppel J., Rovelet-Lecrux A., Hannequin D., Pasquier F., Galimberti D., Scarpini E., Mann D., Lendon C., Campion D., Amouyel P., Davies P., Foskett J.K., Campagne F., Marambaud P. Apolymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell 2008, 133:1149-1161.
6. Feher A., Juhasz A., Rimanoczy A., Pakaski M., Kalman J., Janka Z. No association between CALHM1 polymorphism and Alzheimer's disease risk in a Hungarian population. Psychiatr. Genet. 2011, 21:249-252.
7. Lin K., Tang M., Han H., Guo Y., Lin Y., Ma C. Association between the polymorphisms of CALHM1 and GOLPH2 genes and Alzheimer's disease. Psychiatr. Genet. 2010, 20:190.
8. Minster R.L., Demirci F.Y., DeKosky S.T., Kamboh M.I. No association between CALHM1 variation and risk of Alzheimer disease. Hum. Mutat. 2009, 30:E566-E569.
9. Nacmias B., Tedde A., Bagnoli S., Lucenteforte E., Cellini E., Piaceri I., Guarnieri B.M., Bessi V., Bracco L., Sorbi S. Lack of implication for CALHM1 P86L common variation in Italian patients with early and late onset Alzheimer's disease. J.Alzheimers Dis. 2010, 20:37-41.
10. Sleegers K., Brouwers N., Bettens K., Engelborghs S., van Miegroet H., DeDeyn P.P., Van Broeckhoven C. No association between CALHM1 and risk for Alzheimer dementia in a Belgian population. Hum. Mutat. 2009, 30:E570-E574.