A retrospective analysis of carbapenem-resistant Acinetobacter baumannii-mediated nosocomial pneumonia and the in vitro therapeutic benefit of cefoperazone/sulbactam

International Journal of Infectious Diseases

Volumn 23, Issue , 2014, Pages 90-93

  Xia, Jingjing ^a   Zhang, Duchao ^a   Xu, Yaping ^a   Gong, Meiliang ^a   Zhou, Yu ^a   Fang, Xiangqun ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Acinetobacter baumannii; Carbapenem; Combined drug sensitivity test; Hospital acquired pneumonia

Indexed keywords

BETA LACTAM; C REACTIVE PROTEIN; CARBAPENEM; CARBAPENEMASE; CEFOPERAZONE PLUS SULBACTAM; CREATININE; LEVOFLOXACIN; MEROPENEM; MINOCYCLINE; SERUM ALBUMIN; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE; CEFOPERAZONE; DRUG COMBINATION; SULBACTAM; THIENAMYCIN DERIVATIVE;

ACINETOBACTER BAUMANNII; AGED; ANEMIA; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL THERAPY; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL GENE; BACTERIAL STRAIN; CATHETERIZATION; DRUG SENSITIVITY; FEMALE; GENE AMPLIFICATION; HOSPITAL ACQUIRED PNEUMONIA; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PNEUMONIA; POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; SURVIVAL RATE; VERY ELDERLY; CROSS INFECTION; DRUG COMBINATION; DRUG EFFECTS; DRUG POTENTIATION; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; MIDDLE AGED; MULTIDRUG RESISTANCE; PNEUMONIA, BACTERIAL;

ACINETOBACTER BAUMANNII; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; C-REACTIVE PROTEIN; CARBAPENEMS; CEFOPERAZONE; CROSS INFECTION; DRUG COMBINATIONS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG SYNERGISM; FEMALE; HUMANS; LEVOFLOXACIN; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MINOCYCLINE; PNEUMONIA, BACTERIAL; RETROSPECTIVE STUDIES; SULBACTAM; THIENAMYCINS;

EID: 84899882171     PISSN: 12019712     EISSN: 18783511     Source Type: Journal    
DOI: 10.1016/j.ijid.2014.01.017     Document Type: Article

References (32)

1. Dijkshoorn L., Nemec A., Seifert H. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat Rev Microbiol 2007, 5:939-951.
2. Karageorgopoulos D.E., Falagas M.E. Current control and treatment of multidrug-resistant Acinetobacter baumannii infections. Lancet Infect Dis 2008, 8:751-762.
3. Wada K., Kobayashi Y., Kobayashi O., Sekine O. Pneumonia in the elderly. Nippon Rinsho 2007, 65(Suppl 3):486-489.
4. Zhu D.M., Wang F., Hu F.P., Jiang X.F., Ni Y.X., Sun J.Y., et al. CHINET 2010 surveillance of bacterial resistance in China. Chin J Infect Chemother 2011, 11:321-329.
5. Cisneros J.M., Reyes M.J., Pachón J., Becerril B., Caballero F.J., García-Garmendía J.L., et al. Bacteremia due to Acinetobacter baumannii: epidemiology, clinical findings, and prognostic features. Clin Infect Dis 1996, 22:1026-1032.
6. Gehrlein M., Leying H., Cullmann W., Wendt S., Opferkuch W. Imipenem resistance in Acinetobacter baumannii is due to altered penicillin-binding proteins. Chemotherapy 1991, 37:405-412.
7. Go E.S., Urban C., Burns J., Kreiswirth B., Eisner W., Mariano N., et al. Clinical and molecular epidemiology of Acinetobacter infections sensitive only to polymyxin B and sulbactam. Lancet 1994, 344:1329-1332.
8. Lyytikäinen O., Köljalg S., Härmä M., Vuopio-Varkila J. Outbreak caused by two multi-resistant Acinetobacter baumannii clones in a burns unit: emergence of resistance to imipenem. J Hosp Infect 1995, 31:41-54.
9. Rotstein C., Evans G., Born A., Grossman R., Light R.B., Magder S., et al. Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults. Can J Infect Dis Med Microbiol 2007, 19:19-53.
10. Knaus W.A., Draper E.A., Wagner D.P., Zimmerman J.E. APACHE II: a severity of disease classification system. Crit Care Med 1985, 13:818-829.
11. Fartoukh M., Maitre B., Honoré S., Cerf C., Zahar J.R., Brun-Buisson C. Diagnosing pneumonia during mechanical ventilation: the clinical pulmonary infection score revisited. Am J Respir Crit Care Med 2003, 168:173-179.
12. Performance standards for antimicrobial susceptibility testing. Twenty-first informational supplement. CLSI document M100-S21 2010, Clinical and Laboratory Standards Institute, CLSI, Wayne, PA.
13. Woodford N., Ellington M.J., Coelho J.M., Turton J.F., Ward M.E., Brown S., et al. Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents 2006, 27:351-353.
14. Mendes R.E., Kiyota K.A., Monteiro J., Castanheira M., Andrade S.S., Gales A.C., et al. Rapid detection and identification of metallo-beta-lactamase-encoding genes by multiplex real-time PCR assay and melt curve analysis. J Clin Microbiol 2007, 45:544-547.
15. Lorien V, Eliopoulos GM, Moellering RC Jr. (1996) Antimicrobial combinations. in Antibiotics in laboratory medicine, ed Lorien V. (The Williams & Williams Co. Baltimore, Md), 4th ed. pp 330-396.
16. Siegel S. Nonparametric statistics for the behavioral sciences 1956, McGraw-Hill, New York.
17. O'Brien P.C., Shampo M.A. Statistics for clinicians. 5. One sample of paired observations (paired t test). Mayo Clin Proc 1981, 56:324-326.
18. Moses L.E., Emerson J.D., Hosseini H. Statistics in practice: analyzing data from ordered categories. N Engl J Med 1984, 311:442-448.
19. Myles P.R., Hubbard R.B., McKeever T.M., Pogson Z., Smith C.J., Gibson J.E. Risk of community-acquired pneumonia and the use of statins, ace inhibitors and gastric acid suppressants: a population-based case-control study. Pharmacoepidemiol Drug Saf 2009, 18:269-275.
20. Rodríguez L.A., Ruigómez A., Wallander M.A., Johansson S. Acid-suppressive drugs and community-acquired pneumonia. Epidemiology 2009, 20:800-806.
21. Fortaleza C.M., Abati P.A., Batista M.R., Dias A. Risk factors for hospital-acquired pneumonia in nonventilated adults. Braz J Infect Dis 2009, 13:284-288.
22. Eom C.S., Jeon C.Y., Lim J.W., Cho E.G., Park S.M., Lee K.S. Use of acid-suppressive drugs and risk of pneumonia: a systematic review and meta-analysis. CMAJ 2011, 183:310-319.
23. D'Arezzo S., Principe L., Capone A., Petrosillo N., Petrucca A., Visca P. Changing carbapenemase gene pattern in an epidemic multidrug-resistant Acinetobacter baumannii lineage causing multiple outbreaks in central Italy. J Antimicrob Chemother 2011, 66:54-61.
24. Zheng W., Yuan S., Li L. Analysis of hospital departmental distribution and antibiotic susceptibility of Acinetobacter isolated from sputum samples. Am J Infect Control 2013, 111:134-135.
25. Thatrimontrichai A., Apisarnthanarak A., Chanvitan P., Janjindamai W., Dissaneevate S., Maneenil G. Risk factors and outcomes of carbapenem-resistant Acinetobacter baumannii bacteremia in neonatal intensive care unit: a case-case-control study. Pediatr Infect Dis J 2013, 32:140-145.
26. Kitzis M.D., Goldstein F.W., Labia R., Acar J.F. Activité du sulbactam et de l'acide clavulanique, seuls et associés sur Acinetobacter calcoaceticus. Ann Microbiol (Paris) 1983, 134A:163-168.
27. Labia R., Morand A., Lelievre V., Mattioni D., Kazmierczak A. Sulbactam: biochemical factors involved in its synergy with ampicillin. Rev Infect Dis 1986, 8(Suppl 5):S496-S502.
28. Urban C., Go E., Meyer K.S., Mariano N., Rahal J.J. Interactions of sulbactam, clavulanic acid and tazobactam with penicillin binding proteins of imipenem resistant and susceptible Acinetobacter baumannii. FEMS Microbiol Lett 1995, 125:193-196.
29. Kiratisin P., Apisarnthanarak A., Kaewdaeng S. Synergistic activities between carbapenems and other antimicrobial agents against Acinetobacter baumannii including multidrug-resistant and extensively drug-resistant isolates. Int J Antimicrob Agents 2010, 36:243-246.
30. Pei G., Mao Y., Sun Y. In vitro activity of minocycline alone and in combination with cefoperazone-sulbactam against carbapenem-resistant Acinetobacter baumannii. Microb Drug Resist 2012, 18:574-577.
31. Oliveira M.S., Prado G.V., Costa S.F., Grinbaum R.S., Levin A.S. Ampicillin/sulbactam compared with polymyxins for the treatment of infections caused by carbapenem-resistant Acinetobacter spp. Antimicrob Chemother 2008, 61:1369-1375.
32. Dalla Costa L.M., Coelho J.M., Souza H.A., Castro M.E., Stier C.J., Bragagnolo K.L., et al. Outbreak of carbapenem resistant Acinetobacter baumannii producing OXA-23 enzymes in Curitiba, Brazil. J Clin Microbiol 2003, 41:3403-3406.