The association between influenza treatment and hospitalization-associated outcomes among Korean children with laboratory-confirmed influenza

Journal of Korean Medical Science

Volumn 29, Issue 4, 2014, Pages 485-493

  Lim, Jacqueline K ^a   Kim, Tae Hee ^b   Kilgore, Paul E ^c   Aiello, Allison E ^d   Choi, Byung Min ^e   Lee, Kwang Chul ^e   Yoo, Kee Hwan ^e   Song, Young Hwan ^f   Kim, Yun Kyung ^e  

^a International Vaccine Institute   (South Korea)

^b Asan Medical Center   (South Korea)

^c WAYNE STATE UNIVERSITY   (United States)

^d University of North Carolina at Chapel Hill   (United States)

^e Korea University College of Medicine   (South Korea)

^f Department of Neurology   (South Korea)

Author keywords

Child; Hospitalizations; Influenza, human; Oseltamivir; Therapeutics

Indexed keywords

ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; OSELTAMIVIR; VIRUS ANTIGEN;

ADOLESCENT; CHILD; COHORT ANALYSIS; DEMOGRAPHY; DRUG COMBINATION; FEMALE; HOSPITALIZATION; HUMAN; IMMUNOLOGY; INFANT; INFLUENZA VIRUS A; INFLUENZA VIRUS B; INFLUENZA, HUMAN; MALE; METABOLISM; NEWBORN; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SOUTH KOREA;

ADOLESCENT; ANTI-BACTERIAL AGENTS; ANTIGENS, VIRAL; ANTIVIRAL AGENTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DEMOGRAPHY; DRUG THERAPY, COMBINATION; FEMALE; HOSPITALIZATION; HUMANS; INFANT; INFANT, NEWBORN; INFLUENZA A VIRUS; INFLUENZA B VIRUS; INFLUENZA, HUMAN; MALE; OSELTAMIVIR; REPUBLIC OF KOREA; RETROSPECTIVE STUDIES;

EID: 84899828907     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2014.29.4.485     Document Type: Article

References (42)

1. Molinari NA, Ortega-Sanchez IR, Messonnier ML, Thompson WW, Wortley PM, Weintraub E, Bridges CB. The annual impact of seasonal influenza in the US: measuring disease burden and costs. Vaccine 2007; 25: 5086-96.
2. Newall AT, Scuffham PA. Influenza-related disease: the cost to the Australian healthcare system. Vaccine 2008; 26: 6818-23.
3. Neuzil KM, Wright PF, Mitchel EF Jr, Griffin MR. The burden of influenza illness in children with asthma and other chronic medical conditions. J Pediatr 2000; 137: 856-64.
4. Neuzil KM, Zhu Y, Griffin MR, Edwards KM, Thompson JM, Tollefson SJ, Wright PF. Burden of interpandemic influenza in children younger than 5 years: a 25-year prospective study. J Infect Dis 2002; 185: 147-52.
5. Bhat N, Wright JG, Broder KR, Murray EL, Greenberg ME, Glover MJ, Likos AM, Posey DL, Klimov A, Lindstrom SE, et al. Influenza-associated deaths among children in the United States, 2003-2004. N Engl J Med 2005; 353: 2559-67.
6. Ampofo K, Gesteland PH, Bender J, Mills M, Daly J, Samore M, Byington C, Pavia AT, Srivastava R. Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection. Pediatrics 2006; 118: 2409-17.
7. Keren R, Zaoutis TE, Saddlemire S, Luan XQ, Coffin SE. Direct medical cost of influenza-related hospitalizations in children. Pediatrics 2006; 118: e1321-7.
8. Neuzil KM, Hohlbein C, Zhu Y. Illness among schoolchildren during influenza season: effect on school absenteeism, parental absenteeism from work, and secondary illness in families. Arch Pediatr Adolesc Med 2002; 156: 986-91.
9. Heikkinen T, Silvennoinen H, Peltola V, Ziegler T, Vainionpaa R, Vuorinen T, Kainulainen L, Puhakka T, Jartti T, Toikka P, et al. Burden of influenza in children in the community. J Infect Dis 2004; 190: 1369-73.
10. Kaiser L, Wat C, Mills T, Mahoney P, Ward P, Hayden F. Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalizations. Arch Intern Med 2003; 163: 1667-72.
11. Nicholson KG, Aoki FY, Osterhaus AD, Trottier S, Carewicz O, Mercier CH, Rode A, Kinnersley N, Ward P. Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial: Neuraminidase Inhibitor Flu Treatment Investigator Group. Lancet 2000; 355: 1845-50.
12. Sato M, Saito R, Sato I, Tanabe N, Shobugawa Y, Sasaki A, Li D, Suzuki Y, Sato M, Sakai T, et al. Effectiveness of oseltamivir treatment among chil dren with influenza A or B virus infections during four successive winters in Niigata City, Japan. Tohoku J Exp Med 2008; 214: 113-20.
13. Neuzil KM, Mellen BG, Wright PF, Mitchel EF Jr, Griffin MR. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. N Engl J Med 2000; 342: 225-31.
14. Carrat F, Schwarzinger M, Housset B, Valleron AJ. Antibiotic treatment for influenza does not affect resolution of illness, secondary visits or lost workdays. Eur J Epidemiol 2004; 19: 703-5.
15. Chidiac C, Maulin L. Using antibiotics in case of influenza. Med Mal Infect 2006; 36: 181-9.
16. Cao B, Li R, Liu YM, Cao ZX, Geng XQ, Lau LT, Lu J, Wu L, Cui SF, Bai RT, et al. The impact of antibiotic treatment in patients with influenza-like illness. Zhonghua Jie He He Hu Xi Za Zhi 2008; 31: 483-7.
17. Kee SY, Lee JS, Cheong HJ, Chun BC, Song JY, Choi WS, Jo YM, Seo YB, Kim WJ. Influenza vaccine coverage rates and perceptions on vaccination in South Korea. J Infect 2007; 55: 273-81.
18. Poehling KA, Edwards KM, Weinberg GA, Szilagyi P, Staat MA, Iwane MK, Bridges CB, Grijalva CG, Zhu Y, Bernstein DI, et al. The underrecognized burden of influenza in young children. N Engl J Med 2006; 355: 31-40.
19. Moran K, Maaten S, Guttmann A, Northrup D, Kwong JC. Influenza va-ccination rates in Ontario children: implications for universal childhood vaccination policy. Vaccine 2009; 27: 2350-5.
20. Kim YK, Nyambat B, Hong YS, Lee CG, Lee JW, Kilgore PE. Burden of viral respiratory disease hospitalizations among children in a community of Seoul, Republic of Korea, 1995-2005. Scand J Infect Dis 2008; 40: 946-53.
21. Pee SY, Choi Y, Lee BC, Lee HJ, An HS, Hwang TJ, Lee SY, Seo JG, Oh SH, Hwang YS. Hongchangeui textbook of pediatrics. 8th ed. Seoul: Korean Textbook Press, 2004.
22. Gums JG, Pelletier EM, Blumentals WA. Oseltamivir and influenza-related complications, hospitalization and healthcare expenditure in heal-thy adults and children. Expert Opin Pharmacother 2008; 9: 151-61.
23. Ciesla G, Leader S, Stoddard J. Antibiotic prescribing rates in the US ambulatory care setting for patients diagnosed with influenza, 1997-2001. Respir Med 2004; 98: 1093-101.
24. Reisinger K, Greene G, Aultman R, Sander B, Gyldmark M. Effect of influenza treatment with oseltamivir on health outcome and costs in otherwise healthy children. Clin Drug Investig 2004; 24: 395-407.
25. Hassan F, Lewis TC, Davis MM, Gebremariam A, Dombkowski K. Hospital utilization and costs among children with influenza, 2003. Am J Prev Med 2009; 36: 292-6.
26. Jeong HS. Health care reform and change in public-private mix of financing: a Korean case. Health Policy 2005; 74: 133-45.
27. Ploin D, Gillet Y, Morfin F, Fouilhoux A, Billaud G, Liberas S, Denis A, Thouvenot D, Fritzell B, Lina B, et al. Influenza burden in febrile infants and young children in a pediatric emergency department. Pediatr Infect Dis J 2007; 26: 142-7.
28. Low D. Reducing antibiotic use in influenza: challenges and rewards. Clin Microbiol Infect 2008; 14: 298-306.
29. Noyola DE, Demmler GJ. Effect of rapid diagnosis on management of influenza A infections. Pediatr Infect Dis J 2000; 19: 303-7.
30. De La Rocque F, Lécuyer A, Wollner C, d'Athis P, Pecking M, Thollot F, Cohen R. Impact of influenza rapid diagnostic tests (IRDT) on the diagnosis of influenza and on the management of influenza in children in ambulatory pediatric setting. Arch Pediatr 2009; 16: 288-93.
31. Peltola V, Ziegler T, Ruuskanen O. Influenza A and B virus infections in children. Clin Infect Dis 2003; 36: 299-305.
32. Bonner AB, Monroe KW, Talley LI, Klasner AE, Kimberlin DW. Impact of the rapid diagnosis of influenza on physician decision-making and patient management in the pediatric emergency department: results of a randomized, prospective, controlled trial. Pediatrics 2003; 112: 363-7.
33. Eriksson M, Bennet R, Nilsson A. Wheezing following lower respiratory tract infections with respiratory syncytial virus and influenza A in infancy. Pediatr Allergy Immunol 2000; 11: 193-7.
34. Heymann PW, Carper HT, Murphy DD, Platts-Mills TA, Patrie J, McLaughlin AP, Erwin EA, Shaker MS, Hellems M, Peerzada J, et al. Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing. J Allergy Clin Immunol 2004; 114: 239-47.
35. Lahti E, Peltola V, Virkki R, Ruuskanen O. Influenza pneumonia. Pediatr Infect Dis J 2006; 25: 160-4.
36. Coffin SE, Zaoutis TE, Rosenquist AB, Heydon K, Herrera G, Bridges CB, Watson B, Localio R, Hodinka RL, Keren R. Incidence, complications, and risk factors for prolonged stay in children hospitalized with community-acquired influenza. Pediatrics 2007; 119: 740-8.
37. Daley AJ, Nallusamy R, Isaacs D. Comparison of influenza A and influenza B virus infection in hospitalized children. J Paediatr Child Health 2000; 36: 332-5.
38. Ruiz Laiglesia F, Zubizarreta García J, Agud Aparicio J, Villasante Claudios F, Ayensa Dean C, Sánchez Nanclares M, Torrubia Pérez C. Febrile syndrome in hospitalized patients. An Med Interna 1992; 9: 367-71.
39. Dawood FS, Fiore A, Kamimoto L, Nowell M, Reingold A, Gershman K, Meek J, Hadler J, Arnold KE, Ryan P, et al. Influenza-associated pneumonia in children hospitalized with laboratory-confirmed influenza, 2003-2008. Pediatr Infect Dis J 2010; 29: 585-90.
40. Falagas ME, Vouloumanou EK, Baskouta E, Rafailidis PI, Polyzos K, Rello J. Treatment options for 2009 H1N1 influenza: evaluation of the publish-ed evidence. Int J Antimicrob Agents 2010; 35: 421-30.
41. Fiore AE, Fry A, Shay D, Gubareva L, Bresee JS, Uyeki TM; Centers for Disease Control and Prevention (CDC). Antiviral agents for the treatment and chemoprophylaxis of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2011; 60: 1-24.
42. Jennings LC, Skopnik H, Burckhardt I, Hribar I, Del Piero L, Deichmann KA. Effect of rapid influenza testing on the clinical management of paediatric influenza. Influenza Other Respir Viruses 2009; 3: 91-8.