TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres

Cell Cycle

Volumn 13, Issue 9, 2014, Pages 1463-1481

  D'Alcontres, Martina Stagno ^a   Palacios, Jose Alejandro ^a   Mejias, Diego ^a   Blasco, Maria A ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 BIS(3,5 DIOXO 1 PIPERAZINYL)BUTANE; APC PROTEIN; APHIDICOLIN; BUB1 RELATED PROTEIN; CELL CYCLE PROTEIN 20; CYCLIN B1; DEMECOLCINE; DNA TOPOISOMERASE (ATP HYDROLYSING) A; GEMININ; LAMIN B; NOCODAZOLE; POLO LIKE KINASE 1; PROTEIN MAD1; PROTEIN MAD2; PROTEIN P53; SECURIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TELOMERE BINDING PROTEIN; TELOMERIC REPEAT BINDING FACTOR 1; TUBULIN; BUB1 PROTEIN, HUMAN; CELL CYCLE PROTEIN; DNA; DNA BINDING PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE II ALPHA; MAD1L1 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR ANTIGEN;

ANAPHASE; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CENTROMERE; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME ABERRATION; CHROMOSOME FRAGILITY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA DAMAGE; DNA HELIX; DNA REPLICATION; DOWN REGULATION; FIBROBLAST; GENE DELETION; GENETIC REGULATION; GENOTYPE; HYPOTHESIS; IMMUNOFLUORESCENCE; IN VIVO STUDY; M PHASE CELL CYCLE CHECKPOINT; METAPHASE; MITOSIS; MITOSIS INHIBITION; MOUSE; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PROMETAPHASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SISTER CHROMATID; TELOMERE; TELOPHASE; TIME-LAPSE VIDEO MICROSCOPY; ULTRA THIN DNA BRIDGE; WESTERN BLOTTING; CHROMOSOME FRAGILE SITE; HUMAN; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANTIGENS, NEOPLASM; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CHROMOSOME FRAGILE SITES; DNA; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 1;

EID: 84899748516     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.28419     Document Type: Article

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