메뉴 건너뛰기




Volumn 144, Issue , 2014, Pages

Human hantavirus infections: Epidemiology, clinical features, pathogenesis and immunology

Author keywords

Hantavirus; HCPS; HFRS; Immunology; Pathogenesis

Indexed keywords

METHYLPREDNISOLONE; RIBAVIRIN; STEROID;

EID: 84899736371     PISSN: 14247860     EISSN: 14243997     Source Type: Journal    
DOI: 10.4414/smw.2014.13937     Document Type: Review
Times cited : (103)

References (85)
  • 1
    • 0018089671 scopus 로고
    • Isolation of the etiologic agent of Korean Hemorrhagic fever
    • Available from
    • Lee HW, Lee PW, Johnson KM. Isolation of the etiologic agent of Korean Hemorrhagic fever. J Infect Dis. [Internet]. 1978;137:298-308. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24670.
    • (1978) J Infect Dis. [Internet] , vol.137 , pp. 298-308
    • Lee, H.W.1    Lee, P.W.2    Johnson, K.M.3
  • 2
    • 0000056595 scopus 로고
    • Epidemic hemorrhagic fever
    • Oct [cited 2013 Oct 13]; Available from
    • Smadel JE. Epidemic hemorrhagic fever. Am J Public Health Nations Health. [Internet]. 1953 Oct [cited 2013 Oct 13];43(10):1327-30. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1620469&tool= pmcentrez&rendertype=abstract.
    • (1953) Am J Public Health Nations Health. [Internet] , vol.43 , Issue.10 , pp. 1327-1330
    • Smadel, J.E.1
  • 3
    • 0031113395 scopus 로고    scopus 로고
    • Hantaviruses: A global disease problem
    • Available from
    • Schmaljohn C, Hjelle B. Hantaviruses: a global disease problem. Emerg Infect Dis. [Internet]. 1997;3:95-104. Available from: http://www.pubmedcentral. nih.gov/articlerender.fcgi?artid=2627612&tool=pmcentrez&rendertype= abstract.
    • (1997) Emerg Infect Dis. [Internet] , vol.3 , pp. 95-104
    • Schmaljohn, C.1    Hjelle, B.2
  • 5
    • 0028913214 scopus 로고
    • Identification of a new North American hantavirus that causes acute pulmonary insufficiency
    • Available from
    • Ksiazek TG, Peters CJ, Rollin PE, Zaki S, Nichol S, Spiropoulou C, et al. Identification of a new North American hantavirus that causes acute pulmonary insufficiency. Am J Trop Med Hyg. [Internet]. 1995;52:117-23. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db= PubMed&dopt=Citation&list-uids=7872437.
    • (1995) Am J Trop Med Hyg. [Internet] , vol.52 , pp. 117-123
    • Ksiazek, T.G.1    Peters, C.J.2    Rollin, P.E.3    Zaki, S.4    Nichol, S.5    Spiropoulou, C.6
  • 6
    • 0030937701 scopus 로고    scopus 로고
    • New hantaviruses causing hantavirus pulmonary syndrome in central Argentina
    • Internet Available from
    • López N, Padula P, Rossi C, Lázaro ME, Franze- Fernández MT. New hantaviruses causing hantavirus pulmonary syndrome in central Argentina. [Internet]. Virology. 1997;349:998-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db= PubMed&dopt=Citation&list-uids=9100632.
    • (1997) Virology , vol.349 , pp. 998-999
    • López, N.1    Padula, P.2    Rossi, C.3    Lázaro, M.E.4    Franze-Fernández, M.T.5
  • 7
    • 0033900352 scopus 로고    scopus 로고
    • Genetic Diversity, Distribution, and Serological Features of Hantavirus Infection in Five Countries in South America
    • Available from
    • Padula PJ, Colavecchia SB, Martínez VP, Gonzalez Della Valle MO, Edelstein A, Miguel SDL, et al. Genetic Diversity, Distribution, and Serological Features of Hantavirus Infection in Five Countries in South America. J Clin Microbiol. [Internet]. 2000;38:3029-35. Available from: http://www. pubmedcentral.nih.gov/articlerender.fcgi?artid=87178&tool= pmcentrez&rendertype=abstract.
    • (2000) J Clin Microbiol. [Internet] , vol.38 , pp. 3029-3035
    • Padula, P.J.1    Colavecchia, S.B.2    Martínez, V.P.3    Gonzalez Della Valle, M.O.4    Edelstein, A.5    Miguel, S.D.L.6
  • 8
    • 0034634332 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome in Panama: Identification of novel hantaviruses and their likely reservoirs
    • Available from
    • Vincent MJ, Quiroz E, Gracia F, Sanchez AJ, Ksiazek TG, Kitsutani PT, et al. Hantavirus pulmonary syndrome in Panama: identification of novel hantaviruses and their likely reservoirs. Virology. [Internet]. 2000;277:14-9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11062031.
    • (2000) Virology. [Internet] , vol.277 , pp. 14-19
    • Vincent, M.J.1    Quiroz, E.2    Gracia, F.3    Sanchez, A.J.4    Ksiazek, T.G.5    Kitsutani, P.T.6
  • 9
    • 84906329050 scopus 로고    scopus 로고
    • Hantaviruses as zoonotic pathogens in Germany
    • Jul [cited 2013 Oct 13]; Available from
    • Krüger DH, Ulrich RG, Hofmann J. Hantaviruses as zoonotic pathogens in Germany. Dtsch Arztebl Int. [Internet]. 2013 Jul [cited 2013 Oct 13];110(27-28):461-7. Available from: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid=3722641&tool=pmcentrez&rendertype=abstract.
    • (2013) Dtsch Arztebl Int. [Internet] , vol.110 , Issue.27-28 , pp. 461-467
    • Krüger, D.H.1    Ulrich, R.G.2    Hofmann, J.3
  • 10
    • 84870863730 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome in visitors to a national park - Yosemite Valley, California, 2012
    • Nov 23 [cited 2013 Oct 13]; Available from
    • Hantavirus pulmonary syndrome in visitors to a national park - Yosemite Valley, California, 2012. MMWR Morb Mortal. Wkly Rep [Internet]. 2012 Nov 23 [cited 2013 Oct 13];61(46):952. Available from: http://www.ncbi.nlm.nih.gov/ pubmed/23169317.
    • (2012) MMWR Morb Mortal. Wkly Rep [Internet] , vol.61 , Issue.46 , pp. 952
  • 11
    • 33748704574 scopus 로고    scopus 로고
    • Hantavirus del Nuevo Mundo. Ecologia y epidemiologia de un virus emergente en Latinoamerica
    • Puerta H, Cantillo C, Mills J, Hjelle B, Salazar-Bravo J, Mattar S. The New-World Hantaviruses. Ecology and epidemiology of an emerging virus in Latin America. Med Aires. 2006;66:343-56. (Pubitemid 44390052)
    • (2006) Medicina , vol.66 , Issue.4 , pp. 343-356
    • Puerta, H.1    Cantillo, C.2    Mills, J.3    Hjelle, B.4    Salazar-Bravo, J.5    Mattar, S.6
  • 12
    • 9744262393 scopus 로고    scopus 로고
    • Serologic evidence of hantavirus infection in humans, Colombia
    • Dec [cited 2013 Oct 13]; Available from
    • Máttar S, Parra M. Serologic evidence of hantavirus infection in humans, Colombia. Emerg Infect Dis [Internet]. 2004 Dec [cited 2013 Oct 13];10(12):2263-4. Available from: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid=3323398&tool=pmcentrez&rendertype=abstract.
    • (2004) Emerg Infect Dis [Internet] , vol.10 , Issue.12 , pp. 2263-2264
    • Máttar, S.1    Parra, M.2
  • 13
    • 33747322782 scopus 로고    scopus 로고
    • First serological evidence of Hantavirus infection in rodents in Colombia
    • Available from
    • Alemán A, Iguarán H, Puerta H, Cantillo C, Mills J, Ariz W, et al. First serological evidence of Hantavirus infection in rodents in Colombia. Rev Salud Publica Bogota Colomb [Internet]. 2006;8 Suppl 1:1-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd= Retrieve&db=PubMed&dopt=Citation&list-uids=16925117.
    • (2006) Rev Salud Publica Bogota Colomb [Internet] , vol.8 , Issue.SUPPL. 1 , pp. 1-12
    • Alemán, A.1    Iguarán, H.2    Puerta, H.3    Cantillo, C.4    Mills, J.5    Ariz, W.6
  • 14
    • 19644385912 scopus 로고    scopus 로고
    • Newly recognized hantaviruses associated with hantavirus pulmonary syndrome in northern Brazil: Partial genetic characterization of viruses and serologic implication of likely reservoirs
    • Available from
    • Rosa EST, Mills JN, Padula PJ, Elkhoury MR, Ksiazek TG, Mendes WS, et al. Newly recognized hantaviruses associated with hantavirus pulmonary syndrome in northern Brazil: partial genetic characterization of viruses and serologic implication of likely reservoirs. Vector borne zoonotic Dis Larchmont NY [Internet]. 2005;5:11-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/ query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list-uids=15815145.
    • (2005) Vector Borne Zoonotic Dis Larchmont NY [Internet] , vol.5 , pp. 11-19
    • Rosa, E.S.T.1    Mills, J.N.2    Padula, P.J.3    Elkhoury, M.R.4    Ksiazek, T.G.5    Mendes, W.S.6
  • 15
    • 84868105466 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome (Rio Mamore virus) in the Peruvian Amazon region
    • cited 2013 Oct 13; Available from
    • Casapía M, Mamani E, García MP, Miraval ML, Valencia P, Quino AH, et al. [Hantavirus pulmonary syndrome (Rio Mamore virus) in the Peruvian Amazon region]. Rev Peru Med Exp Salud Publica [Internet]. [cited 2013 Oct 13];29(3):390-5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 23085803.
    • Rev Peru Med Exp Salud Publica [Internet] , vol.29 , Issue.3 , pp. 390-395
    • Casapía, M.1    Mamani, E.2    García, M.P.3    Miraval, M.L.4    Valencia, P.5    Quino, A.H.6
  • 19
    • 52649136188 scopus 로고    scopus 로고
    • First Case of Hantavirus Cardiopulmonary Syndrome Occurring after a Rodent Bite
    • Merino C, Arias A, Castillo C. First Case of Hantavirus Cardiopulmonary Syndrome Occurring after a Rodent Bite. Rev Chil Enf Respir. 2002;18:199-205.
    • (2002) Rev Chil Enf Respir , vol.18 , pp. 199-205
    • Merino, C.1    Arias, A.2    Castillo, C.3
  • 20
    • 33746850512 scopus 로고    scopus 로고
    • Prolonged survival of Puumala hantavirus outside the host: Evidence for indirect transmission via the environment
    • Kallio ER, Klingström J, Gustafsson E, Manni T, Vaheri A, Henttonen H, et al. Prolonged survival of Puumala hantavirus outside the host: evidence for indirect transmission via the environment. J Gen Virol. 2006;87:2127-34.
    • (2006) J Gen Virol , vol.87 , pp. 2127-2134
    • Kallio, E.R.1    Klingström, J.2    Gustafsson, E.3    Manni, T.4    Vaheri, A.5    Henttonen, H.6
  • 22
    • 84875349793 scopus 로고    scopus 로고
    • UK hantavirus, renal failure, and pet rats
    • Mar 23 [cited 2013 Oct 13]; Available from
    • Taori SK, Jameson LJ, Campbell A, Drew PJ, McCarthy ND, Hart J, et al. UK hantavirus, renal failure, and pet rats. Lancet [Internet]. 2013 Mar 23 [cited 2013 Oct 13];381(9871):1070. Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 23668557.
    • (2013) Lancet [Internet] , vol.381 , Issue.9871 , pp. 1070
    • Taori, S.K.1    Jameson, L.J.2    Campbell, A.3    Drew, P.J.4    McCarthy, N.D.5    Hart, J.6
  • 23
    • 84880027494 scopus 로고    scopus 로고
    • Pet rat harbouring Seoul hantavirus in Sweden, June 2013
    • [cited 2013 Oct 13];Jul 4 pii: 20521. Available from
    • Lundkvist A, Verner-Carlsson J, Plyusnina A, Forslund L, Feinstein R PA. Pet rat harbouring Seoul hantavirus in Sweden, June 2013. Euro Surveill [Internet]. 2013 [cited 2013 Oct 13];Jul 4(18(27)):pii: 20521. Available from: http://www.eurosurveillance.org/images/dynamic/EE/V18N27/art20521.pdf.
    • (2013) Euro Surveill [Internet] , vol.18 , Issue.27
    • Lundkvist, A.1    Verner-Carlsson, J.2    Plyusnina, A.3    Forslund, L.4    Feinstein, R.5    P, A.6
  • 25
    • 78649554193 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome in Argentina, 1995-2008
    • Dec [cited 2013 Oct 13]; Available from
    • Martinez VP, Bellomo CM, Cacace ML, Suarez P, Bogni L, Padula PJ. Hantavirus pulmonary syndrome in Argentina, 1995-2008. Emerg Infect Dis [Internet]. 2010 Dec [cited 2013 Oct 13];16(12):1853-60. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3294556&tool= pmcentrez&rendertype=abstract.
    • (2010) Emerg Infect Dis [Internet] , vol.16 , Issue.12 , pp. 1853-1860
    • Martinez, V.P.1    Bellomo, C.M.2    Cacace, M.L.3    Suarez, P.4    Bogni, L.5    Padula, P.J.6
  • 26
    • 34249042292 scopus 로고    scopus 로고
    • Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in chile
    • Available from
    • Ferres M, Vial P, Marco C, Yanez L, Godoy P, Castillo C, et al. Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in chile. J Infect Dis [Internet]. 2007;195:1563-71. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17471425.
    • (2007) J Infect Dis [Internet] , vol.195 , pp. 1563-1571
    • Ferres, M.1    Vial, P.2    Marco, C.3    Yanez, L.4    Godoy, P.5    Castillo, C.6
  • 27
    • 1642372343 scopus 로고    scopus 로고
    • Prevalence of antibodies to hantavirus among family and health care worker contacts of persons with hantavirus cardiopulmonary syndrome: Lack of evidence for nosocomial transmission of Andes virus to health care workers in Chile
    • Mar; Available from
    • Castillo C, Villagra E, Sanhueza L, Ferres M, Mardones J, Mertz GJ. Prevalence of antibodies to hantavirus among family and health care worker contacts of persons with hantavirus cardiopulmonary syndrome: lack of evidence for nosocomial transmission of Andes virus to health care workers in Chile. Am J Trop Med Hyg [Internet]. 2004 Mar;70(3):302-4. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15031521.
    • (2004) Am J Trop Med Hyg [Internet] , vol.70 , Issue.3 , pp. 302-304
    • Castillo, C.1    Villagra, E.2    Sanhueza, L.3    Ferres, M.4    Mardones, J.5    Mertz, G.J.6
  • 28
    • 0032519398 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome outbreak in Argentina: Molecular evidence for person-to-person transmission of Andes virus
    • Available from
    • Padula PJ, Edelstein A, Miguel SD, López NM, Rossi CM, Rabinovich RD. Hantavirus pulmonary syndrome outbreak in Argentina: molecular evidence for person-to-person transmission of Andes virus. Virology [Internet]. 1998;241:323-30. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9674243.
    • (1998) Virology [Internet] , vol.241 , pp. 323-330
    • Padula, P.J.1    Edelstein, A.2    Miguel, S.D.3    López, N.M.4    Rossi, C.M.5    Rabinovich, R.D.6
  • 31
    • 84930478627 scopus 로고    scopus 로고
    • Incidence rate for hantavirus infections without pulmonary syndrome, Panama
    • Oct [cited 2013 Oct 13]; Available from
    • Armien B, Pascale JM, Munoz C, Lee S-J, Choi KL, Avila M, et al. Incidence rate for hantavirus infections without pulmonary syndrome, Panama. Emerg Infect Dis [Internet]. 2011 Oct [cited 2013 Oct 13];17(10):1936-9. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid= 3310655&tool=pmcentrez&rendertype=abstract.
    • (2011) Emerg Infect Dis [Internet] , vol.17 , Issue.10 , pp. 1936-1939
    • Armien, B.1    Pascale, J.M.2    Munoz, C.3    Lee, S.-J.4    Choi, K.L.5    Avila, M.6
  • 32
    • 0031657256 scopus 로고    scopus 로고
    • High prevalence of hantavirus infection in Indian communities of the Paraguayan and Argentinean Gran Chaco
    • Sep; Available from
    • Ferrer JF, Jonsson CB, Esteban E, Galligan D, Basombrio M a, Peralta-Ramos M, et al. High prevalence of hantavirus infection in Indian communities of the Paraguayan and Argentinean Gran Chaco. Am J Trop Med Hyg [Internet]. 1998 Sep;59(3):438-44. Available from: http://www.ncbi.nlm.nih.gov/ pubmed/9749641.
    • (1998) Am J Trop Med Hyg [Internet] , vol.59 , Issue.3 , pp. 438-444
    • Ferrer, J.F.1    Jonsson, C.B.2    Esteban, E.3    Galligan, D.4    Basombrio, M.A.5    Peralta-Ramos, M.6
  • 33
    • 0030967907 scopus 로고    scopus 로고
    • An outbreak of hantavirus pulmonary syndrome in western Paraguay
    • Sep [cited 2013 Oct 13]; Available from
    • Williams RJ, Bryan RT, Mills JN, Palma RE, Vera I, De Velasquez F, et al. An outbreak of hantavirus pulmonary syndrome in western Paraguay. Am J Trop Med Hyg [Internet]. 1997 Sep [cited 2013 Oct 13];57(3):274-82. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9311636.
    • (1997) Am J Trop Med Hyg [Internet] , vol.57 , Issue.3 , pp. 274-282
    • Williams, R.J.1    Bryan, R.T.2    Mills, J.N.3    Palma, R.E.4    Vera, I.5    De Velasquez, F.6
  • 34
    • 83055173116 scopus 로고    scopus 로고
    • Seroprevalence study in forestry workers of a non-endemic region in eastern Germany reveals infections by Tula and Dobrava-Belgrade hantaviruses
    • Mertens M, Hofmann J, Petraityte-Burneikiene R, Ziller M, Sasnauskas K, Friedrich R, et al. Seroprevalence study in forestry workers of a non-endemic region in eastern Germany reveals infections by Tula and Dobrava-Belgrade hantaviruses. Med. Microbiol. Immunol. 2011;200(4):263-8.
    • (2011) Med. Microbiol. Immunol. , vol.200 , Issue.4 , pp. 263-268
    • Mertens, M.1    Hofmann, J.2    Petraityte-Burneikiene, R.3    Ziller, M.4    Sasnauskas, K.5    Friedrich, R.6
  • 35
    • 33846677611 scopus 로고    scopus 로고
    • Cross-sectional survey on hantavirus seroprevalence in Canton St. Gallen, Switzerland
    • Schultze D, Fierz W, Matter HC, Bankoul S, Niedrig M, Schmiedl A. Cross-sectional survey on hantavirus seroprevalence in Canton St. Gallen, Switzerland. Swiss Med Wkly Off J Swiss Soc Infect Dis Swiss Soc Intern Med Swiss Soc Pneumol. 2007;137:21-6. (Pubitemid 46191227)
    • (2007) Swiss Medical Weekly , vol.137 , Issue.1-2 , pp. 21-26
    • Schultze, D.1    Fierz, W.2    Matter, H.C.3    Bankoul, S.4    Niedrig, M.5    Schmiedl, A.6
  • 37
    • 84862901062 scopus 로고    scopus 로고
    • Rise in the number of notified human hantavirus infections since October 2011 in Baden-Wurttemberg, Germany
    • May 24 [cited 2014 Jan 1]; Available from
    • Boone I, Wagner-Wiening C, Reil D, Jacob J, Rosenfeld UM, Ulrich RG, et al. Rise in the number of notified human hantavirus infections since October 2011 in Baden-Wurttemberg, Germany. Euro Surveill [Internet]. 2012 May 24 [cited 2014 Jan 1];17(21). Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 22687824.
    • (2012) Euro Surveill [Internet] , vol.17 , Issue.21
    • Boone, I.1    Wagner-Wiening, C.2    Reil, D.3    Jacob, J.4    Rosenfeld, U.M.5    Ulrich, R.G.6
  • 38
    • 0037280525 scopus 로고    scopus 로고
    • Hantaviruses. A short review
    • Jan [cited 2013 Oct 13]; Available from
    • Lednicky JA. Hantaviruses. a short review. Arch Pathol Lab Med [Internet]. 2003 Jan [cited 2013 Oct 13];127(1):30-5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12521363.
    • (2003) Arch Pathol Lab Med [Internet] , vol.127 , Issue.1 , pp. 30-35
    • Lednicky, J.A.1
  • 39
    • 84874163151 scopus 로고    scopus 로고
    • Signs of general inflammation and kidney function are associated with the ocular features of acute Puumala hantavirus infection
    • Hautala N, Kauma H, Rajaniemi S-M, Sironen T, Vapalahti O, Pääkkö E, et al. Signs of general inflammation and kidney function are associated with the ocular features of acute Puumala hantavirus infection. Scand. J. Infect. Dis. 2012;44(12):1-7.
    • (2012) Scand. J. Infect. Dis. , vol.44 , Issue.12 , pp. 1-7
    • Hautala, N.1    Kauma, H.2    Rajaniemi, S.-M.3    Sironen, T.4    Vapalahti, O.5    Pääkkö, E.6
  • 40
    • 0000004674 scopus 로고    scopus 로고
    • Bunyaviruses
    • Knipe DM, Howley PM, eds. 4th ed Philadelphia, Pa Lippincott Williams Wilkins
    • Nichol ST. Bunyaviruses. In: Knipe DM, Howley PM, eds. Field's Virol Vol 2, 4th ed Philadelphia, Pa Lippincott Williams Wilkins. 2001. p. 1603-33.
    • (2001) Field's Virol , vol.2 , pp. 1603-1633
    • Nichol, S.T.1
  • 41
    • 84880435410 scopus 로고    scopus 로고
    • Uncovering the mysteries of hantavirus infections
    • Aug [cited 2013 Oct 13]; Available from
    • Vaheri A, Strandin T, Hepojoki J, Sironen T, Henttonen H, Mäkelä S, et al. Uncovering the mysteries of hantavirus infections. Nat Rev Microbiol [Internet]. 2013 Aug [cited 2013 Oct 13];11(8):539-50. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24020072.
    • (2013) Nat Rev Microbiol [Internet] , vol.11 , Issue.8 , pp. 539-550
    • Vaheri, A.1    Strandin, T.2    Hepojoki, J.3    Sironen, T.4    Henttonen, H.5    Mäkelä, S.6
  • 42
    • 33750599116 scopus 로고    scopus 로고
    • Incubation period of hantavirus cardiopulmonary syndrome
    • Aug [cited 2013 Oct 13]; Available from
    • Vial PA, Valdivieso F, Mertz G, Castillo C, Belmar E, Delgado I, et al. Incubation period of hantavirus cardiopulmonary syndrome. Emerg Infect Dis [Internet]. 2006 Aug [cited 2013 Oct 13];12(8):1271-3. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3291207&tool= pmcentrez&rendertype=abstract.
    • (2006) Emerg Infect Dis [Internet] , vol.12 , Issue.8 , pp. 1271-1273
    • Vial, P.A.1    Valdivieso, F.2    Mertz, G.3    Castillo, C.4    Belmar, E.5    Delgado, I.6
  • 43
    • 0242292072 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome, southern Chile
    • Nov [cited 2013 Oct 13]; Available from
    • Riquelme R, Riquelme M, Torres A, Rioseco ML, Vergara JA, Scholz L, et al. Hantavirus pulmonary syndrome, southern Chile. Emerg Infect Dis [Internet]. 2003 Nov [cited 2013 Oct 13];9(11):1438-43. Available from: http://www.ncbi.nlm. nih.gov/pubmed/14718088.
    • (2003) Emerg Infect Dis [Internet] , vol.9 , Issue.11 , pp. 1438-1443
    • Riquelme, R.1    Riquelme, M.2    Torres, A.3    Rioseco, M.L.4    Vergara, J.A.5    Scholz, L.6
  • 44
    • 0030067420 scopus 로고    scopus 로고
    • Cardiopulmonary manifestations of hantavirus pulmonary syndrome
    • Feb [cited 2013 Oct 13]; Available from
    • Hallin GW, Simpson SQ, Crowell RE, James DS, Koster FT, Mertz GJ, et al. Cardiopulmonary manifestations of hantavirus pulmonary syndrome. Crit Care Med [Internet]. 1996 Feb [cited 2013 Oct 13];24(2):252-8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8605797.
    • (1996) Crit Care Med [Internet] , vol.24 , Issue.2 , pp. 252-258
    • Hallin, G.W.1    Simpson, S.Q.2    Crowell, R.E.3    James, D.S.4    Koster, F.T.5    Mertz, G.J.6
  • 45
    • 0028215049 scopus 로고
    • Hantavirus pulmonary syndrome: A clinical description of 17 patients with a newly recognized disease
    • The Hantavirus Study Group. Apr 7 [cited 2013 Oct 13]; Available from
    • Duchin JS, Koster FT, Peters CJ, Simpson GL, Tempest B, Zaki SR, et al. Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. The Hantavirus Study Group. N Engl J Med [Internet]. 1994 Apr 7 [cited 2013 Oct 13];330(14):949-55. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8121458.
    • (1994) N Engl J Med [Internet] , vol.330 , Issue.14 , pp. 949-955
    • Duchin, J.S.1    Koster, F.T.2    Peters, C.J.3    Simpson, G.L.4    Tempest, B.5    Zaki, S.R.6
  • 46
    • 70349297650 scopus 로고    scopus 로고
    • Pulmonary and cardiovascular syndrome due to hantavirus: Clinical aspects of an emerging disease in southeastern Brazil
    • cited 2013 Oct 13; Available from
    • Campos GM, Borges AA, Badra SJ, Figueiredo GG, Souza RLM de, Moreli ML, et al. [Pulmonary and cardiovascular syndrome due to hantavirus: clinical aspects of an emerging disease in southeastern Brazil]. Rev Soc Bras Med Trop [Internet]. 2009 [cited 2013 Oct 13];42(3):282-9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19684976.
    • (2009) Rev Soc Bras Med Trop [Internet] , vol.42 , Issue.3 , pp. 282-289
    • Campos, G.M.1    Borges, A.A.2    Badra, S.J.3    Figueiredo, G.G.4    De Souza, R.L.M.5    Moreli, M.L.6
  • 47
    • 0034827892 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome due to Andes virus in Temuco, Chile: Clinical experience with 16 adults
    • Aug [cited 2013 Oct 13]; Available from
    • Castillo C, Naranjo J, Sepúlveda A, Ossa G, Levy H. Hantavirus pulmonary syndrome due to Andes virus in Temuco, Chile: clinical experience with 16 adults. Chest [Internet]. 2001 Aug [cited 2013 Oct 13];120(2):548-54. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11502657.
    • (2001) Chest [Internet] , vol.120 , Issue.2 , pp. 548-554
    • Castillo, C.1    Naranjo, J.2    Sepúlveda, A.3    Ossa, G.4    Levy, H.5
  • 48
    • 79959982323 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome: Encephalitis caused by virus Andes
    • Apr [cited 2013 Oct 13]; Available from
    • Talamonti L, Padula PJ, Canteli MS, Posner F, Marczeski FP, Weller C. Hantavirus pulmonary syndrome: encephalitis caused by virus Andes. J Neurovirol [Internet]. 2011 Apr [cited 2013 Oct 13];17(2):189-92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21240581.
    • (2011) J Neurovirol [Internet] , vol.17 , Issue.2 , pp. 189-192
    • Talamonti, L.1    Padula, P.J.2    Canteli, M.S.3    Posner, F.4    Marczeski, F.P.5    Weller, C.6
  • 49
    • 84886876724 scopus 로고    scopus 로고
    • Hantavirus fever without pulmonary syndrome in Panama
    • Sep [cited 2014 Jan 1]; Available from
    • Armien B, Pascale JM, Muñoz C, Mariñas J, Núñez H, Herrera M, et al. Hantavirus fever without pulmonary syndrome in Panama. Am J Trop Med Hyg [Internet]. 2013 Sep [cited 2014 Jan 1];89(3):489-94. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23836565.
    • (2013) Am J Trop Med Hyg [Internet] , vol.89 , Issue.3 , pp. 489-494
    • Armien, B.1    Pascale, J.M.2    Muñoz, C.3    Mariñas, J.4    Núñez, H.5    Herrera, M.6
  • 50
    • 84884377717 scopus 로고    scopus 로고
    • High-dose intravenous methylprednisolone for hantavirus cardiopulmonary syndrome in chile: A double-blind, randomized controlled clinical trial
    • Oct [cited 2013 Oct 13]; Available from
    • Vial PA, Valdivieso F, Ferres M, Riquelme R, Rioseco ML, Calvo M, et al. High-dose intravenous methylprednisolone for hantavirus cardiopulmonary syndrome in chile: a double-blind, randomized controlled clinical trial. Clin Infect Dis [Internet]. 2013 Oct [cited 2013 Oct 13];57(7):943-51. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23784924.
    • (2013) Clin Infect Dis [Internet] , vol.57 , Issue.7 , pp. 943-951
    • Vial, P.A.1    Valdivieso, F.2    Ferres, M.3    Riquelme, R.4    Rioseco, M.L.5    Calvo, M.6
  • 51
    • 77957581062 scopus 로고    scopus 로고
    • Convalescent pulmonary dysfunction following hantavirus pulmonary syndrome in Panama and the United States
    • Oct [cited 2013 Oct 13]; Available from
    • Gracia F, Armien B, Simpson SQ, Munoz C, Broce C, Pascale JM, et al. Convalescent pulmonary dysfunction following hantavirus pulmonary syndrome in Panama and the United States. Lung [Internet]. 2010 Oct [cited 2013 Oct 13];188(5):387-91. Available from: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid=2939327&tool=pmcentrez&rendertype=abstract.
    • (2010) Lung [Internet] , vol.188 , Issue.5 , pp. 387-391
    • Gracia, F.1    Armien, B.2    Simpson, S.Q.3    Munoz, C.4    Broce, C.5    Pascale, J.M.6
  • 52
    • 0027431303 scopus 로고
    • Utilization of autopsy RNA for the synthesis of the nucleocapsid antigen of a newly recognized virus associated with hantavirus pulmonary syndrome
    • Dec [cited 2013 Oct 13]; Available from
    • Feldmann H, Sanchez A, Morzunov S, Spiropoulou CF, Rollin PE, Ksiazek TG, et al. Utilization of autopsy RNA for the synthesis of the nucleocapsid antigen of a newly recognized virus associated with hantavirus pulmonary syndrome. Virus Res [Internet]. 1993 Dec [cited 2013 Oct 13];30(3):351-67. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8109165.
    • (1993) Virus Res [Internet] , vol.30 , Issue.3 , pp. 351-367
    • Feldmann, H.1    Sanchez, A.2    Morzunov, S.3    Spiropoulou, C.F.4    Rollin, P.E.5    Ksiazek, T.G.6
  • 53
    • 17644431966 scopus 로고    scopus 로고
    • Serological diagnosis of hantavirus infections by an enzyme-linked immunosorbent assay based on detection of immunoglobulin G and M responses to recombinant nucleocapsid proteins of five viral serotypes
    • May [cited 2013 Oct 13]; Available from
    • Elgh F, Lundkvist A, Alexeyev OA, Stenlund H, Avsic-Zupanc T, Hjelle B, et al. Serological diagnosis of hantavirus infections by an enzyme-linked immunosorbent assay based on detection of immunoglobulin G and M responses to recombinant nucleocapsid proteins of five viral serotypes. J Clin Microbiol [Internet]. 1997 May [cited 2013 Oct 13];35(5):1122-30. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=232715&tool= pmcentrez&rendertype=abstract.
    • (1997) J Clin Microbiol [Internet] , vol.35 , Issue.5 , pp. 1122-1130
    • Elgh, F.1    Lundkvist, A.2    Alexeyev, O.A.3    Stenlund, H.4    Avsic-Zupanc, T.5    Hjelle, B.6
  • 54
    • 0031045038 scopus 로고    scopus 로고
    • Rapid and specific detection of Sin Nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis
    • Mar [cited 2013 Oct 13]; Available from
    • Hjelle B, Jenison S, Torrez-Martinez N, Herring B, Quan S, Polito A, et al. Rapid and specific detection of Sin Nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis. J Clin Microbiol [Internet]. 1997 Mar [cited 2013 Oct 13];35(3):600-8. Available from: http://www.pubmedcentral.nih.gov/articlerender. fcgi?artid=229635&tool=pmcentrez&rendertype=abstract.
    • (1997) J Clin Microbiol [Internet] , vol.35 , Issue.3 , pp. 600-608
    • Hjelle, B.1    Jenison, S.2    Torrez-Martinez, N.3    Herring, B.4    Quan, S.5    Polito, A.6
  • 55
    • 31144457887 scopus 로고    scopus 로고
    • Serological assays for the detection of human Andes hantavirus infections based on its yeast-expressed nucleocapsid protein
    • Jan [cited 2013 Sep 26]; Available from
    • Schmidt J, Meisel H, Capria SG, Petraityte R, Lundkvist a, Hjelle B, et al. Serological assays for the detection of human Andes hantavirus infections based on its yeast-expressed nucleocapsid protein. Intervirology [Internet]. 2006 Jan [cited 2013 Sep 26];49(3):173-84. Available from: http://www.ncbi.nlm. nih.gov/pubmed/16428893.
    • (2006) Intervirology [Internet] , vol.49 , Issue.3 , pp. 173-184
    • Schmidt, J.1    Meisel, H.2    Capria, S.G.3    Petraityte, R.4    Lundkvist, A.5    Hjelle, B.6
  • 56
    • 84876837076 scopus 로고    scopus 로고
    • Indirect immunofluorescence assay for the simultaneous detection of antibodies against clinically important old and new world hantaviruses
    • Jan [cited 2013 Oct 13]; Available from
    • Lederer S, Lattwein E, Hanke M, Sonnenberg K, Stoecker W, Lundkvist Å, et al. Indirect immunofluorescence assay for the simultaneous detection of antibodies against clinically important old and new world hantaviruses. PLoS Negl Trop Dis [Internet]. 2013 Jan [cited 2013 Oct 13];7(4):e2157. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid= 3617148&tool=pmcentrez&rendertype=abstract.
    • (2013) PLoS Negl Trop Dis [Internet] , vol.7 , Issue.4
    • Lederer, S.1    Lattwein, E.2    Hanke, M.3    Sonnenberg, K.4    Stoecker, W.5    Lundkvist, Å.6
  • 57
    • 0033983775 scopus 로고    scopus 로고
    • Development and evaluation of a solid-phase enzyme immunoassay based on Andes hantavirus recombinant nucleoprotein
    • Feb [cited 2013 Oct 13]; Available from
    • Padula PJ, Rossi CM, Della Valle MO, Martínez P V, Colavecchia SB, Edelstein A, et al. Development and evaluation of a solid-phase enzyme immunoassay based on Andes hantavirus recombinant nucleoprotein. J Med Microbiol [Internet]. 2000 Feb [cited 2013 Oct 13];49(2):149-55. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10670565
    • (2000) J Med Microbiol [Internet] , vol.49 , Issue.2 , pp. 149-155
    • Padula, P.J.1    Rossi, C.M.2    Della Valle, M.O.3    Martínez, P.V.4    Colavecchia, S.B.5    Edelstein, A.6
  • 58
    • 0032977170 scopus 로고    scopus 로고
    • High levels of cytokine-producing cells in the lung tissues of patients with fatal hantavirus pulmonary syndrome
    • Feb [cited 2013 Oct 13]; Available from
    • Mori M, Rothman AL, Kurane I, Montoya JM, Nolte KB, Norman JE, et al. High levels of cytokine-producing cells in the lung tissues of patients with fatal hantavirus pulmonary syndrome. J Infect Dis [Internet]. 1999 Feb [cited 2013 Oct 13];179(2):295-302. Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 9878011.
    • (1999) J Infect Dis [Internet] , vol.179 , Issue.2 , pp. 295-302
    • Mori, M.1    Rothman, A.L.2    Kurane, I.3    Montoya, J.M.4    Nolte, K.B.5    Norman, J.E.6
  • 59
    • 84875978198 scopus 로고    scopus 로고
    • Hantavirus-infection confers resistance to cytotoxic lymphocyte-mediated apoptosis
    • Mar [cited 2013 Oct 13]; Available from
    • Gupta S, Braun M, Tischler ND, Stoltz M, Sundström KB, Björkström NK, et al. Hantavirus-infection confers resistance to cytotoxic lymphocyte-mediated apoptosis. PLoS Pathog [Internet]. 2013 Mar [cited 2013 Oct 13];9(3):e1003272. Available from: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid=3610645&tool=pmcentrez&rendertype=abstract.
    • (2013) PLoS Pathog [Internet] , vol.9 , Issue.3
    • Gupta, S.1    Braun, M.2    Tischler, N.D.3    Stoltz, M.4    Sundström, K.B.5    Björkström, N.K.6
  • 60
    • 1342340346 scopus 로고    scopus 로고
    • Cl I, II III HLA alleles Assoc with Sev hantavirus Cardiopulm Syndr southwest US
    • Abstr.
    • Koster F, Vigil J, Olson D, Terajima M, Ennis F, Al. E. Am J Trop Med 65: (Abstr.). Cl I, II III HLA alleles Assoc with Sev hantavirus Cardiopulm Syndr southwest US. 2001.
    • (2001) Am J Trop Med , vol.65
    • Koster, F.1    Vigil, J.2    Olson, D.3    Terajima, M.4    Ennis, F.5
  • 61
    • 36249018472 scopus 로고    scopus 로고
    • Genetic susceptibility to Andes Hantavirus: Association between severity of disease and HLA alíeles in Chilean patients
    • Available from
    • Ferrer C P, Vial C PA, Ferrés G M, Godoy M P, Culza V A, Marco C C, et al. Genetic susceptibility to Andes Hantavirus: Association between severity of disease and HLA alíeles in Chilean patients. Rev Chil Infectol organo Of la Soc Chil Infectol [Internet]. 2007;24:351-9. Available from: http://www.scielo.cl/scielo.php?script=sci-arttext&pid=S0716- 10182007000500001&lng=en&nrm=62
    • (2007) Rev Chil Infectol Organo of la Soc Chil Infectol [Internet] , vol.24 , pp. 351-359
    • Ferrer, C.P.1    Vial, C.P.A.2    Ferrés, G.M.3    Godoy, M.P.4    Culza, V.A.5    Marco, C.C.6
  • 62
    • 77649264983 scopus 로고    scopus 로고
    • Highly Differentiated, Resting Gn-Specific Memory CD8+ T Cells Persist Years after Infection by Andes Hantavirus
    • Available from
    • Manigold T, Mori A, Graumann R, Llop E, Simon V, Ferrés M, et al. Highly Differentiated, Resting Gn-Specific Memory CD8+ T Cells Persist Years after Infection by Andes Hantavirus. PLoS Pathog [Internet]. 2010;6:16. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid= 2824805&tool=pmcentrez&rendertype=abstract.
    • (2010) PLoS Pathog [Internet] , vol.6 , pp. 16
    • Manigold, T.1    Mori, A.2    Graumann, R.3    Llop, E.4    Simon, V.5    Ferrés, M.6
  • 63
    • 54749107098 scopus 로고    scopus 로고
    • Case report: T-cell responses during clearance of Andes virus from blood cells 2 months after severe hantavirus cardiopulmonary syndrome
    • Internet Available from
    • Manigold T, Martinez J, Lazcano X, Ye C, Schwartz S, Cuiza A, et al. Case report: T-cell responses during clearance of Andes virus from blood cells 2 months after severe hantavirus cardiopulmonary syndrome. [Internet]. J. Med. Virol. 2008. p. 1947-51. Available from: http://www.ncbi.nlm.nih.gov/entrez/ query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list-uids=18814258.
    • (2008) J. Med. Virol. , pp. 1947-1951
    • Manigold, T.1    Martinez, J.2    Lazcano, X.3    Ye, C.4    Schwartz, S.5    Cuiza, A.6
  • 64
    • 80053939265 scopus 로고    scopus 로고
    • T cells are not required for pathogenesis in the Syrian hamster model of hantavirus pulmonary syndrome
    • Oct [cited 2013 Oct 13]; Available from
    • Hammerbeck CD, Hooper JW. T cells are not required for pathogenesis in the Syrian hamster model of hantavirus pulmonary syndrome. J Virol [Internet]. 2011 Oct [cited 2013 Oct 13];85(19):9929-44. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3196444&tool= pmcentrez&rendertype=abstract.
    • (2011) J Virol [Internet] , vol.85 , Issue.19 , pp. 9929-9944
    • Hammerbeck, C.D.1    Hooper, J.W.2
  • 65
    • 84880424062 scopus 로고    scopus 로고
    • The adaptive immune response does not influence hantavirus disease or persistence in the Syrian hamster
    • Oct [cited 2013 Oct 13]; Available from
    • Prescott J, Safronetz D, Haddock E, Robertson S, Scott D, Feldmann H. The adaptive immune response does not influence hantavirus disease or persistence in the Syrian hamster. Immunology [Internet]. 2013 Oct [cited 2013 Oct 13];140(2):168-78. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23600567.
    • (2013) Immunology [Internet] , vol.140 , Issue.2 , pp. 168-178
    • Prescott, J.1    Safronetz, D.2    Haddock, E.3    Robertson, S.4    Scott, D.5    Feldmann, H.6
  • 66
    • 84873848988 scopus 로고    scopus 로고
    • Hantavirus regulation of type I interferon responses
    • Jan [cited 2013 Oct 13]; Available from
    • Matthys V, Mackow ER. Hantavirus regulation of type I interferon responses. Adv Virol [Internet]. 2012 Jan [cited 2013 Oct 13];2012:524024. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid= 3423653&tool=pmcentrez&rendertype=abstract.
    • (2012) Adv Virol [Internet] , vol.2012 , pp. 524024
    • Matthys, V.1    Mackow, E.R.2
  • 67
    • 0034530465 scopus 로고    scopus 로고
    • Cellular receptors and hantavirus pathogenesis
    • Jan [cited 2013 Oct 13]; Available from
    • Mackow ER, Gavrilovskaya IN. Cellular receptors and hantavirus pathogenesis. Curr Top Microbiol Immunol [Internet]. 2001 Jan [cited 2013 Oct 13];256:91-115. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11217408.
    • (2001) Curr Top Microbiol Immunol [Internet] , vol.256 , pp. 91-115
    • Mackow, E.R.1    Gavrilovskaya, I.N.2
  • 68
    • 37549022214 scopus 로고    scopus 로고
    • IFN-beta protects from vascular leakage via up-regulation of CD73
    • Dec [cited 2013 Oct 13]; Available from
    • Kiss J, Yegutkin GG, Koskinen K, Savunen T, Jalkanen S, Salmi M. IFN-beta protects from vascular leakage via up-regulation of CD73. Eur J Immunol [Internet]. 2007 Dec [cited 2013 Oct 13];37(12):3334-8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18034430.
    • (2007) Eur J Immunol [Internet] , vol.37 , Issue.12 , pp. 3334-3338
    • Kiss, J.1    Yegutkin, G.G.2    Koskinen, K.3    Savunen, T.4    Jalkanen, S.5    Salmi, M.6
  • 69
    • 84872310808 scopus 로고    scopus 로고
    • Dengue virus type 2 modulates endothelial barrier function through CD73
    • Jan [cited 2013 Oct 13]; Available from
    • Patkar C, Giaya K, Libraty DH. Dengue virus type 2 modulates endothelial barrier function through CD73. Am J Trop Med Hyg [Internet]. 2013 Jan [cited 2013 Oct 13];88(1):89-94. Available from: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid=3541750&tool=pmcentrez&rendertype=abstract.
    • (2013) Am J Trop Med Hyg [Internet] , vol.88 , Issue.1 , pp. 89-94
    • Patkar, C.1    Giaya, K.2    Libraty, D.H.3
  • 70
    • 0032946942 scopus 로고    scopus 로고
    • Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins
    • May [cited 2013 Oct 13]; Available from
    • Gavrilovskaya IN, Brown EJ, Ginsberg MH, Mackow ER. Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins. J Virol [Internet]. 1999 May [cited 2013 Oct 13];73(5):3951-9. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid= 104173&tool=pmcentrez&rendertype=abstract.
    • (1999) J Virol [Internet] , vol.73 , Issue.5 , pp. 3951-3959
    • Gavrilovskaya, I.N.1    Brown, E.J.2    Ginsberg, M.H.3    Mackow, E.R.4
  • 71
    • 34250768894 scopus 로고    scopus 로고
    • Platelet integrin alpha(IIb)beta(3): Activation mechanisms
    • Jul [cited 2013 Sep 22]; Available from
    • Ma Y-Q, Qin J, Plow EF. Platelet integrin alpha(IIb)beta(3): activation mechanisms. J Thromb Haemost [Internet]. 2007 Jul [cited 2013 Sep 22];5(7):1345-52. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17635696.
    • (2007) J Thromb Haemost [Internet] , vol.5 , Issue.7 , pp. 1345-1352
    • Ma, Y.-Q.1    Qin, J.2    Plow, E.F.3
  • 72
    • 0033914497 scopus 로고    scopus 로고
    • Humoral immune responses in the hantavirus cardiopulmonary syndrome
    • Jul [cited 2013 Oct 13]; Available from
    • Bharadwaj M, Nofchissey R, Goade D, Koster F, Hjelle B. Humoral immune responses in the hantavirus cardiopulmonary syndrome. J Infect Dis [Internet]. 2000 Jul [cited 2013 Oct 13];182(1):43-8. Available from: http://www.ncbi.nlm. nih.gov/pubmed/10882580.
    • (2000) J Infect Dis [Internet] , vol.182 , Issue.1 , pp. 43-48
    • Bharadwaj, M.1    Nofchissey, R.2    Goade, D.3    Koster, F.4    Hjelle, B.5
  • 74
    • 0032712251 scopus 로고    scopus 로고
    • High levels of viremia in patients with the Hantavirus pulmonary syndrome
    • Dec [cited 2013 Oct 13]; Available from
    • Terajima M, Hendershot JD, Kariwa H, Koster FT, Hjelle B, Goade D, et al. High levels of viremia in patients with the Hantavirus pulmonary syndrome. J Infect Dis [Internet]. 1999 Dec [cited 2013 Oct 13];180(6):2030-4. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10558964.
    • (1999) J Infect Dis [Internet] , vol.180 , Issue.6 , pp. 2030-2034
    • Terajima, M.1    Hendershot, J.D.2    Kariwa, H.3    Koster, F.T.4    Hjelle, B.5    Goade, D.6
  • 75
    • 9644272538 scopus 로고    scopus 로고
    • Kinetics of protective antibodies are determined by the viral surface antigen
    • Oct [cited 2013 Oct 13]; Available from
    • Pinschewer DD, Perez M, Jeetendra E, Bächi T, Horvath E, Hengartner H, et al. Kinetics of protective antibodies are determined by the viral surface antigen. J Clin Invest [Internet]. 2004 Oct [cited 2013 Oct 13];114(7):988-93. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid= 518669&tool=pmcentrez&rendertype=abstract.
    • (2004) J Clin Invest [Internet] , vol.114 , Issue.7 , pp. 988-993
    • Pinschewer, D.D.1    Perez, M.2    Jeetendra, E.3    Bächi, T.4    Horvath, E.5    Hengartner, H.6
  • 76
    • 84874774602 scopus 로고    scopus 로고
    • HLA-A2 and B35 restricted hantaan virus nucleoprotein CD8+ T-cell epitope-specific immune response correlates with milder disease in hemorrhagic fever with renal syndrome
    • Jan [cited 2013 Oct 8]; Available from
    • Ma Y, Wang J, Yuan B, Wang M, Zhang Y, Xu Z, et al. HLA-A2 and B35 restricted hantaan virus nucleoprotein CD8+ T-cell epitope-specific immune response correlates with milder disease in hemorrhagic fever with renal syndrome. PLoS Negl Trop Dis [Internet]. 2013 Jan [cited 2013 Oct 8];7(2):e2076. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid= 3585118&tool=pmcentrez&rendertype=abstract.
    • (2013) PLoS Negl Trop Dis [Internet] , vol.7 , Issue.2
    • Ma, Y.1    Wang, J.2    Yuan, B.3    Wang, M.4    Zhang, Y.5    Xu, Z.6
  • 77
    • 84899749753 scopus 로고    scopus 로고
    • Induction of Protective Immunity in a Syrian Hamster Model Against a Cytopathogenic Strain of Andes Virus
    • Martinez VP, Padula PJ. Induction of Protective Immunity in a Syrian Hamster Model Against a Cytopathogenic Strain of Andes Virus. Cell. 2012;95:87-95.
    • (2012) Cell , vol.95 , pp. 87-95
    • Martinez, V.P.1    Padula, P.J.2
  • 78
    • 0025838388 scopus 로고
    • Prospective, double-blind, concurrent, placebo-controlled clinical trial of intravenous ribavirin therapy of hemorrhagic fever with renal syndrome
    • Dec [cited 2013 Oct 13]; Available from
    • Huggins JW, Hsiang CM, Cosgriff TM, Guang MY, Smith JI, Wu ZO, et al. Prospective, double-blind, concurrent, placebo-controlled clinical trial of intravenous ribavirin therapy of hemorrhagic fever with renal syndrome. J Infect Dis [Internet]. 1991 Dec [cited 2013 Oct 13];164(6):1119-27. Available from: http://www.ncbi.nlm.nih.gov/pubmed/1683355.
    • (1991) J Infect Dis [Internet] , vol.164 , Issue.6 , pp. 1119-1127
    • Huggins, J.W.1    Hsiang, C.M.2    Cosgriff, T.M.3    Guang, M.Y.4    Smith, J.I.5    Wu, Z.O.6
  • 79
    • 0036467252 scopus 로고    scopus 로고
    • Discriminators between hantavirus-infected and -uninfected persons enrolled in a trial of intravenous ribavirin for presumptive hantavirus pulmonary syndrome
    • Feb 1 [cited 2013 Oct 13]; Available from
    • Chapman LE, Ellis BA, Koster FT, Sotir M, Ksiazek TG, Mertz GJ, et al. Discriminators between hantavirus-infected and -uninfected persons enrolled in a trial of intravenous ribavirin for presumptive hantavirus pulmonary syndrome. Clin Infect Dis [Internet]. 2002 Feb 1 [cited 2013 Oct 13];34(3):293-304. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11774075.
    • (2002) Clin Infect Dis [Internet] , vol.34 , Issue.3 , pp. 293-304
    • Chapman, L.E.1    Ellis, B.A.2    Koster, F.T.3    Sotir, M.4    Ksiazek, T.G.5    Mertz, G.J.6
  • 80
    • 7644244053 scopus 로고    scopus 로고
    • Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America
    • Nov 1 [cited 2013 Oct 13]; Available from
    • Mertz GJ, Miedzinski L, Goade D, Pavia AT, Hjelle B, Hansbarger CO, et al. Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America. Clin Infect Dis [Internet]. 2004 Nov 1 [cited 2013 Oct 13];39(9):1307-13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15494907.
    • (2004) Clin Infect Dis [Internet] , vol.39 , Issue.9 , pp. 1307-1313
    • Mertz, G.J.1    Miedzinski, L.2    Goade, D.3    Pavia, A.T.4    Hjelle, B.5    Hansbarger, C.O.6
  • 81
    • 80051519131 scopus 로고    scopus 로고
    • In vitro and in vivo activity of ribavirin against Andes virus infection
    • Jan [cited 2013 Oct 13]; Available from
    • Safronetz D, Haddock E, Feldmann F, Ebihara H, Feldmann H. In vitro and in vivo activity of ribavirin against Andes virus infection. PLoS One [Internet]. 2011 Jan [cited 2013 Oct 13];6(8):e23560. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3154477&tool= pmcentrez&rendertype=abstract.
    • (2011) PLoS One [Internet] , vol.6 , Issue.8
    • Safronetz, D.1    Haddock, E.2    Feldmann, F.3    Ebihara, H.4    Feldmann, H.5
  • 82
    • 79551692297 scopus 로고    scopus 로고
    • VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability
    • Mar [cited 2013 Oct 13]; Available from
    • Gorbunova EE, Gavrilovskaya IN, Pepini T, Mackow ER. VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability. J Virol [Internet]. 2011 Mar [cited 2013 Oct 13];85(5):2296-303. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3067787&tool= pmcentrez&rendertype=abstract.
    • (2011) J Virol [Internet] , vol.85 , Issue.5 , pp. 2296-2303
    • Gorbunova, E.E.1    Gavrilovskaya, I.N.2    Pepini, T.3    Mackow, E.R.4
  • 84
    • 0037992775 scopus 로고    scopus 로고
    • Vaccines against hantaviruses
    • Oct [cited 2013 Oct 13]; Available from
    • Hjelle B. Vaccines against hantaviruses. Expert Rev Vaccines [Internet]. 2002 Oct [cited 2013 Oct 13];1(3):373-84. Available from: http://www.ncbi.nlm. nih.gov/pubmed/12901576.
    • (2002) Expert Rev Vaccines [Internet] , vol.1 , Issue.3 , pp. 373-384
    • Hjelle, B.1
  • 85
    • 84882878769 scopus 로고    scopus 로고
    • A novel Sin Nombre virus DNA vaccine and its inclusion in a candidate pan-hantavirus vaccine against hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS)
    • Sep 13 [cited 2013 Oct 13]; Available from
    • Hooper JW, Josleyn M, Ballantyne J, Brocato R. A novel Sin Nombre virus DNA vaccine and its inclusion in a candidate pan-hantavirus vaccine against hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). Vaccine [Internet]. 2013 Sep 13 [cited 2013 Oct 13];31(40):4314-21. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23892100.
    • (2013) Vaccine [Internet] , vol.31 , Issue.40 , pp. 4314-4321
    • Hooper, J.W.1    Josleyn, M.2    Ballantyne, J.3    Brocato, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.