Optimizing P2Y12 receptor inhibition in patients with acute coronary syndrome on the basis of platelet function testing: Impact of prasugrel and high-dose clopidogrel

Journal of the American College of Cardiology

Volumn 63, Issue 11, 2014, Pages 1061-1070

  Aradi, Dániel ^a   Tornyos, Adrienn ^b   Pintér, Tünde ^b   Vorobcsuk, András ^b   Kónyi, Attila ^b   Faluközy, József ^a   Veress, Gábor ^a   Magyari, Balázs ^b   Horváth, Iván G ^b   Komócsi, András ^b  

^a Heart Center Balatonfüred   (Hungary)

^b UNIVERSITY OF PÉCS   (Hungary)

Author keywords

bleeding; high platelet reactivity; high dose clopidogrel; mortality; PCI; platelet function testing; prasugrel; stent thrombosis

Indexed keywords

CLOPIDOGREL; PRASUGREL; PURINERGIC P2Y12 RECEPTOR; DRUG DERIVATIVE; PIPERAZINE DERIVATIVE; PURINERGIC P2Y RECEPTOR ANTAGONIST; THIOPHENE DERIVATIVE; TICLOPIDINE;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; BLEEDING; BLOOD CLOTTING PARAMETERS; CORONARY STENT; CORONARY STENTING; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG POTENCY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEDICAL DEVICE COMPLICATION; PERCUTANEOUS CORONARY INTERVENTION; PLATELET REACTIVITY; PROSPECTIVE STUDY; SINGLE DRUG DOSE; STENT THROMBOSIS; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE FUNCTION; THROMBOCYTE FUNCTION ANALYZER; THROMBOSIS; TREATMENT OUTCOME; AGED; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; COMPARATIVE STUDY; CONFIDENCE INTERVAL; DRUG ADMINISTRATION; EVALUATION STUDY; HEART INFARCTION; HIGH PLATELET REACTIVITY; HIGH-DOSE CLOPIDOGREL; KAPLAN MEIER METHOD; METHODOLOGY; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; PCI; PLATELET FUNCTION TESTING; PREDICTIVE VALUE; PROPORTIONAL HAZARDS MODEL; REGISTER; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STENT; SURVIVAL RATE; TRANSLUMINAL CORONARY ANGIOPLASTY;

BLEEDING; HIGH PLATELET REACTIVITY; HIGH-DOSE CLOPIDOGREL; MORTALITY; PCI; PLATELET FUNCTION TESTING; PRASUGREL; STENT THROMBOSIS;

ACUTE CORONARY SYNDROME; AGED; ANGIOPLASTY, BALLOON, CORONARY; CAUSE OF DEATH; COMBINED MODALITY THERAPY; CONFIDENCE INTERVALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HEMORRHAGE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PIPERAZINES; PLATELET FUNCTION TESTS; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; PURINERGIC P2Y RECEPTOR ANTAGONISTS; REGISTRIES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STENTS; STROKE; SURVIVAL RATE; THIOPHENES; THROMBOSIS; TICLOPIDINE; TREATMENT OUTCOME;

EID: 84899713032     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.12.023     Document Type: Article

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