Microscopic computed tomography-based virtual histology of embryos

Methods in Molecular Biology

Volumn 1092, Issue , 2014, Pages 291-296

  Prajapati, Suresh I ^a   Rodriguez, David R ^a   Keller, Charles ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

High resolution phenotyping of embryos; microCT; Virtual histology

Indexed keywords

OSMIUM TETRAOXIDE;

ANIMAL EXPERIMENT; ARTICLE; EMBRYO; HISTOLOGY; INTERMETHOD COMPARISON; MAGNETIC RESONANCE MICROSCOPY; MICRO-COMPUTED TOMOGRAPHY; MICROSCOPY; MOUSE; MOUSE EMBRYO; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ANIMAL; ANIMAL EMBRYO; COMPUTER ASSISTED TOMOGRAPHY; METHODOLOGY; MOLECULAR BIOLOGY; THREE DIMENSIONAL IMAGING; ULTRASTRUCTURE; ANIMAL TISSUE; EMBRYO (ANATOMY); MICROSCOPIC COMPUTED TOMOGRAPHY; STAINING; VIRTUAL HISTOLOGY; X RAY;

ANIMALS; EMBRYO, MAMMALIAN; HISTOLOGICAL TECHNIQUES; IMAGING, THREE-DIMENSIONAL; MICE; MICROSCOPY; MOLECULAR BIOLOGY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84899710066     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60327-292-6_19     Document Type: Article

References (12)

1. Johnson JT, Hansen MS, Wu I, Healy LJ, Johnson CR, Jones GM, Capecchi MR, Keller C (2006) Virtual histology of transgenic mouse embryos for high-throughput phenotyping. PLoS Genet 2:e61
2. Capecchi MR (2005) Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat Rev Genet 6:507-512
3. Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B (2004) The knockout mouse project. Nat Genet 36:921-924
4. Floss T, Schnutgen F (2008) EUCOMM-the European conditional mouse mutagenesis program. Methods Mol Biol 435:127-138
5. Friedel RH, Seisenberger C, Kaloff C, Wurst W (2007) Conditional gene trapping using the FLEx system. Brief Funct Genomic Proteomic 6:180-185
6. Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J (2004) A public gene trap resource for mouse functional genomics. Nat Genet 36:543-544
7. Jacobs RE, Ahrens ET, Dickinson ME, Laidlaw D (1999) Towards a microMRI atlas of mouse development. Comput Med Imaging Graph 23:15-24
8. Smith BR, Johnson GA, Groman EV, Linney E (1994) Magnetic resonance microscopy of mouse embryos. Proc Natl Acad Sci U S A 91:3530-3533
9. Schneider JE, Bhattacharya S (2004) Making the mouse embryo transparent:Identifying developmental malformations using magnetic resonance imaging. Birth Defects Res C Embryo Today 72:241-249
10. Tyszka JM, Fraser SE, Jacobs RE (2005) Magnetic resonance microscopy: recent advances and applications. Curr Opin Biotechnol 16:93-99
11. Schneider JE, Bamforth SD, Farthing CR, Clarke K, Neubauer S, Bhattacharya S (2003) High-resolution imaging of normal anatomy, and neural and adrenal malformations in mouse embryos using magnetic resonance microscopy. J Anat 202:239-247
12. Smith BR, Linney E, Huff DS, Johnson GA (1996) Magnetic resonance microscopy of embryos. Comput Med Imaging Graph 20:483-490