Bioaccumulation of microcystins (MCs) in four fish species from Lake Taihu, China: Assessment of risks to humans

Science of the Total Environment

Volumn 487, Issue 1, 2014, Pages 224-232

  Jia, Junmei ^a,b   Luo, Wei ^a   Lu, Yonglong ^a   Giesy, John P ^c,d  

^a RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Accumulation; Asia; Cyanotoxins; Eutrophication; Hazard; Hazardous algal bloom

Indexed keywords

BIOMARKERS; EUTROPHICATION; HAZARDS; HEALTH; HEALTH RISKS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LAKES; MASS SPECTROMETRY; MUSCLE; RISK ASSESSMENT; TOXIC MATERIALS;

ACCUMULATION; ALGAL BLOOMS; ASIA; CYANOTOXINS; ESTIMATED DAILY INTAKES; HARMFUL ALGAL BLOOMS; TOLERABLE DAILY INTAKE; WORLD HEALTH ORGANIZATION;

FISH;

MICROCYSTIN; MICROCYSTIN LR; MICROCYSTIN RR; MICROCYSTIN YR; UNCLASSIFIED DRUG;

ALGAL BLOOM; BIOACCUMULATION; BODY MASS; EUTROPHICATION; FISH; FOOD CONSUMPTION; FOOD INTAKE; HEALTH IMPACT; RISK ASSESSMENT; TOXIN; TROPHIC LEVEL; WORLD HEALTH ORGANIZATION;

ARISTICHTHYS NOBILIS; ARTICLE; BIOACCUMULATION; BODY HEIGHT; BODY MASS; CARP; CHINA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIETARY REFERENCE INTAKE; FOOD INTAKE; GEOGRAPHIC DISTRIBUTION; GOLDFISH; HEALTH HAZARD; HEALTH IMPACT ASSESSMENT; HEART; HIGH RISK POPULATION; HYPOPHTHALMICHTHYS MOLITRIX; INTESTINE WALL; KIDNEY; MUSCLE; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT;

CHINA; JIANGSU; MEILIANG BAY; TAIHU LAKE;

ACCUMULATION; ASIA; CYANOTOXINS; EUTROPHICATION; HAZARD; HAZARDOUS ALGAL BLOOM;

ANIMALS; CHINA; ENVIRONMENTAL MONITORING; FISHES; FOOD CONTAMINATION; HUMANS; LAKES; MICROCYSTINS; RISK ASSESSMENT; WATER POLLUTANTS, CHEMICAL;

EID: 84899701953     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2014.04.037     Document Type: Article

References (53)

1. Acuna S., Deng D.F., Lehman P., Teh S. Sublethal dietary effects of microcystis on Sacramento splittail, Pogonichthys macrolepidotus. Aquat Toxicol 2012, 110:1-8.
2. Ame M.V., Galanti L.N., Menone M.L., Gerpe M.S., Moreno V.J., Wunderlin D.A. Microcystin-LR, -RR, -YR and -LA in water samples and fishes from a shallow lake in Argentina. Harmful Algae 2010, 9:66-73.
3. Authority T.B. Taihu Lake health status report 2011, 14-15.
4. Carmichael W.W. Cyanobacterial secondary metabolites - the cyanotoxins. J Appl Bacteriol 1992, 72:445-459.
5. Carmichael W.W. The toxins of cyanobacteria. Sci Am 1994, 270:78-86.
6. Cazenave J., Wunderlin D.A., Bistoni M.D.L.Á., Amé M.V., Krause E., Pflugmacher S., et al. Uptake, tissue distribution and accumulation of microcystin-RR in Corydoras paleatus, Jenynsia multidentata and Odontesthes bonariensis: a field and laboratory study. Aquat Toxicol 2005, 75:178-190.
7. Chen Q., Mynett A.E. Integration of data mining techniques and heuristic knowledge in fuzzy logic modelling of eutrophication in Taihu Lake. Ecol Model 2003, 162:55-67.
8. Chen J., Xie P. Seasonal dynamics of the hepatotoxic microcystins in various organs of four freshwater bivalves from the large eutrophic Lake Taihu of subtropical China and the risk to human consumption. Environ Toxicol 2005, 20:572-584.
9. Chen J., Xie P. Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in two freshwater shrimps, Palaemon modestus and Macrobrachium nipponensis, from a large shallow, eutrophic lake of the subtropical China. Toxicon 2005, 45:615-625.
10. Chen Y.F., Zhu S.Q. Change of fish fauna and long-term dynamics of the harvest of aquatic product in a large shallow lake (Lake Taihu, China). J Fish Aquat Sci 2008, 3:72-76.
11. Chen J., Xie P., Zhang D.W., Ke Z.X., Yang H. In situ studies on the bioaccumulation of microcystins in the phytoplanktivorous silver carp (Hypophthalmichthys molitrix) stocked in Lake Taihu with dense toxic Microcystis blooms. Aquaculture 2006, 261:1026-1038.
12. Chen J., Xie P., Li L., Xu J. First identification of the hepatotoxic microcystins in the serum of a chronically exposed human population together with indication of hepatocellular damage. Toxicol Sci 2009, 108:81-89.
13. Chorus I., Bartram J. Toxic cyanobacteria in water: a guide to their public health consequences, monitoring and management 1999, E & FN Spon, London and New York.
14. Dawson R.M. The toxicology of microcystins. Toxicon 1998, 36:953-962.
15. Gkelis S., Lanaras T., Sivonen K. The presence of microcystins and other cyanobacterial bioactive peptides in aquatic fauna collected from Greek freshwaters. Aquat Toxicol 2006, 78:32-41.
16. Gupta N., Pant S.C., Vijayaraghavan R., Rao P.V.L. Comparative toxicity evaluation of cyanobacterial cyclic peptide toxin microcystin variants (LR, RR, YR) in mice. Toxicology 2003, 188:285-296.
17. Ibelings B.W., Chorus I. Accumulation of cyanobacterial toxins in freshwater "seafood" and its consequences for public health: a review. Environ Pollut 2007, 150:177-192.
18. Jiang J.L., Gu X.Y., Song R., Zhang Q., Geng J.J., Wang X.R., et al. Time-dependent oxidative stress and histopathological changes in Cyprinus carpio L. exposed to microcystin-LR. Ecotoxicology 2011, 20:1000-1009.
19. Jin X., Hu X. A comprehensive plan for treating the major polluted regions of Lake Taihu, China. Lakes Reserv Res Manag 2003, 8:217-230.
20. Kaebernick M., Neilan B.A. Ecological and molecular investigations of cyanotoxin production. FEMS Microbiol Ecol 2001, 35:1-9.
21. Kankaanpää H.T., Holliday J., Schröder H., Goddard T.J., von Fister R., Carmichael W.W. Cyanobacteria and prawn farming in northern New South Wales, Australia-a case study on cyanobacteria diversity and hepatotoxin bioaccumulation. Toxicol Appl Pharmacol 2005, 203:243-256.
22. Kotak B.G., Semalulu S., Fritz D.L., Prepas E.E., Hrudey S.E., Coppock R.W. Hepatic and renal pathology of intraperitoneally administered microcystin-LR in rainbow trout (Oncorhynchus mykiss). Toxicon 1996, 34:517-525.
23. Li J.Z. Agilent 1260 UHPLC/6460QQQ used for the detection of microcystins. Environ Chem 2011, 30:731-733.
24. Li X.Y., Chung I.K., Kim J.I., Lee J.A. Subchronic oral toxicity of microcystin in common carp (Cyprinus carpio L.) exposed to Microcystis under laboratory conditions. Toxicon 2004, 44:821-827.
25. Li L., Xie P., Chen J. In vivo studies on toxin accumulation in liver and ultrastructural changes of hepatocytes of the phytoplanktivorous bighead carp i.p.-injected with extracted microcystins. Toxicon 2005, 46:533-545.
26. Li Z.L., Yu J.W., Yang M., Zhang J., Burch M.D., Han W. Cyanobacterial population and harmful metabolites dynamics during a bloom in Yanghe Reservoir, North China. Harmful Algae 2010, 9:481-488.
27. Liu E.S. A study on diet composition of dominant fishes in Lake Taihu (in Chinese). J Fish China 2008, 32:395-401.
28. Magalhàes V.F., Soares R.M., Azvedo S. Microcystin contamination in fish from Jacarepaguá Lagoon (Rio de Janeiro, Brazil): ecological implication and human health risk. Toxicon 2001, 39:1077-1085.
29. Magalhaes V.F., Soares R.M., Azevedo S.M. Microcystin contamination in fish from the Jacarepagua Lagoon (Rio de Janeiro, Brazil): ecological implication and human health risk. Toxicon 2001, 39:1077-1085.
30. Magalhães V.F., Marinho M.M., Domingos P., Oliveira A.C., Costa S.M., Azevedo L.O., et al. Microcystins (cyanobacteria hepatotoxins) bioaccumulation in fish and crustaceans from Sepetiba Bay (Brasil, RJ). Toxicon 2003, 42:289-295.
31. Malbrouck C., Trausch G., Devos P., Kestemont P. Hepatic accumulation and effects of microcystin-LR on juvenile goldfish Carassius auratus L. Comp Biochem Physiol C Toxicol Pharmacol 2003, 135:39-48.
32. McElhiney J., Lawton L.A. Detection of the cyanobacterial hepatotoxins microcystins. Toxicol Appl Pharmacol 2005, 203:219-230.
33. Melwani A.R., Bezalel S.N., Hunt J.A., Grenier J.L., Ichikawa G., Heim W., et al. Spatial trends and impairment assessment of mercury in sport fish in the Sacramento-San Joaquin Delta watershed. Environ Pollut 2009, 157:3137-3149.
34. Mohamed Z.A., Hussein A.A. Depuration of microcystins in tilapia fish exposed to natural populations of toxic cyanobacteria: a laboratory study. Ecotoxicol Environ Saf 2006, 63:424-429.
35. Mohamed Z.A., Carmichael W.W., Hussein A.A. Estimation of microcystins in the freshwater fish Oreochromis niloticus in an Egyptian fish farm containing a Microcystis bloom. Environ Toxicol 2003, 18:137-141.
36. Nishiwakimatsushima R., Ohta T., Nishiwaki S., Suganuma M., Kohyama K., Ishikawa T., et al. Liver-tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. J Cancer Res Clin Oncol 1992, 118:420-424.
37. Otten T.G., Xu H., Qin B., Zhu G., Paerl H.W. Spatiotemporal patterns and ecophysiology of toxigenic microcystis blooms in Lake Taihu, China: implications for water quality management. Environ Sci Technol 2012, 46:3480-3488.
38. Pan G., Chen J., Anderson D.M. Modified local sands for the mitigation of harmful algal blooms. Harmful Algae 2011, 10:381-387.
39. Pavagadhi S., Gong Z.Y., Hande M.P., Dionysiou D.D., de la Cruz A.A., Balasubramanian R. Biochemical response of diverse organs in adult Danio rerio (zebrafish) exposed to sub-lethal concentrations of microcystin-LR and microcystin-RR: a balneation study. Aquat Toxicol 2012, 109:1-10.
40. Peng L.A., Liu Y.M., Chen W., Liu L.M., Kent M., Song L.R. Health risks associated with consumption of microcystin-contaminated fish and shellfish in three Chinese lakes: significance for freshwater aquacultures. Ecotoxicol Environ Saf 2010, 73:1804-1811.
41. Pu P.M., Hu W.P., Yan J.S., Wang G.X., Hu C.H. A physico-ecological engineering experiment for water treatment in a hypertrophic lake in China. Ecol Eng 1998, 10:179-190.
42. Qiu T., Xie P., Ke Z., Li L., Guo L. In situ studies on physiological and biochemical responses of four fishes with different trophic levels to toxic cyanobacterial blooms in a large Chinese lake. Toxicon 2007, 50:365-376.
43. Qiu T., Xie P., Ke Z.X., Li L., Guo L.G. In situ studies on physiological and biochemical responses of four fishes with different trophic levels to toxic cyanobacterial blooms in a large Chinese lake. Toxicon 2007, 50:365-376.
44. Sun X., Tao M., Qin B., Qi M., Niu Y., Zhang J., et al. Large-scale field evidence on the enhancement of small-sized cladocerans by Microcystis blooms in Lake Taihu, China. J Plankton Res 2012, 34:853-863.
45. Tencalla F., Dietrich D. Biochemical characterization of microcystin toxicity in rainbow trout (Oncorhynchus mykiss). Toxicon 1997, 35:583-595.
46. Vasconcelos V.M., Pereira E. Cyanobacteria diversity and toxicity in a wastewater treatment plant (Portugal). Water Res 2001, 35:1354-1357.
47. Williams D.E., Dawe S.C., Kent M.L., Andersen R.J., Craig M., Holmes C.F.B. Bioaccumulation and clearance of microcystins from salt water, mussels, Mytilus edulis, and in vivo evidence for covalently bound microcystins in mussel tissues. Toxicon 1997, 35:1617-1625.
48. Xie P., Liu J. Practical success of biomanipulation using filter-feeding fish to control cyanobacteria blooms: a synthesis of decades of research and application in a subtropical hypereutrophic lake. ScientificWorldJournal 2001, 1:337-356.
49. Xie L.Q., Xie P., Ozawa K., Honma T., Yokoyama A., Park H.D. Dynamics of microcystins-LR and -RR in the phytoplanktivorous silver carp in a sub-chronic toxicity experiment. Environ Pollut 2004, 127:431-439.
50. Xie L.Q., Xie P., Guo L.G., Li L., Miyabara Y., Park H.D. Organ distribution and bioaccumulation of microcystins in freshwater fish at different trophic levels from the eutrophic Lake Chaohu, China. Environ Toxicol 2005, 20:293-300.
51. Zhang D.W., Xie P., Liu Y.Q., Qiu T. Transfer, distribution and bioaccumulation of microcystins in the aquatic food web in Lake Taihu, China, with potential risks to human health. Sci Total Environ 2009, 407:2191-2199.
52. Zhang J.Q., Wang Z., Song Z.Y., Xie Z.C., Li L., Song L.R. Bioaccumulation of microcystins in two freshwater gastropods from a cyanobacteria-bloom plateau lake, Lake Dianchi. Environ Pollut 2012, 164:227-234.
53. Zurawell R.W., Kotak B.G., Prepas E.E. Influence of lake trophic status on the occurrence of microcystin-LR in the tissue of pulmonate snails. Freshw Biol 1999, 42:707-718.