Genotoxic effects and serum abnormalities in residents of regions proximal to e-waste disposal facilities in Jinghai, China

Ecotoxicology and Environmental Safety

Volumn 105, Issue 1, 2014, Pages 51-58

  Li, KeQiu ^a   Liu, ShaSha ^b   Yang, QiaoYun ^c   Zhao, YuXia ^a   Zuo, JunFang ^b   Li, Ran ^c   Jing, YaQing ^a   He, XiaoBo ^a   Qiu, XingHua ^c   Li, Guang ^a   Zhu, Tong ^c  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Tianjin Central Hospital of Gynecology Obstetrics   (China)

^c Ministry of Ecology and Environment of the People's Republic of China   (China)

Author keywords

Electronic waste; Genetic damage; Lymphocyte subsets; Malondialdehyde; Micronucleus; Persistent organic pollutants

Indexed keywords

CALCIUM; COPPER; FAS ANTIGEN; INTERLEUKIN 7 RECEPTOR; IRON; LEAD; MAGNESIUM; MALONALDEHYDE; RNA; SELENIUM; ZINC;

ABNORMALITY; BLOOD; COPPER; EXPERIMENTAL STUDY; GENOTOXICITY; LEAD; ORGANIC POLLUTANT; SERUM; TRACE ELEMENT; WASTE DISPOSAL; WASTE MANAGEMENT; ZINC;

ADULT; ARTICLE; BLOOD SAMPLING; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHINA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTRONIC WASTE; FEMALE; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE SUBPOPULATION; MALE; MICRONUCLEUS; ORGANIC POLLUTION; REGULATORY T LYMPHOCYTE; SEX DIFFERENCE; WASTE DISPOSAL;

CHINA; JINGHAI; TIANJIN;

ELECTRONIC WASTE; GENETIC DAMAGE; LYMPHOCYTE SUBSETS; MALONDIALDEHYDE; MICRONUCLEUS; PERSISTENT ORGANIC POLLUTANTS;

ADULT; ANTIGENS, CD; BLOOD CHEMICAL ANALYSIS; CHINA; ELECTRONIC WASTE; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LYMPHOCYTES; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MIDDLE AGED; TRANSCRIPTOME; WASTE DISPOSAL FACILITIES;

EID: 84899689625     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2014.03.034     Document Type: Article

References (24)

1. Alabi O., Bakare A. Genotoxicity and mutagenicity of electronic waste leachates using animal bioassays. Toxicol. Environ. Chem. 2011, 93:1073-1088.
2. Bakare A., Adeyemi A., Adeyemi A., Alabi O., Osibanjo O. Cytogenotoxic effects of electronic waste leachate in Allium cepa. Int. J. Cytol. 2012, 65(2):94-100.
3. Baudin-Creuza V., Vasseur-Godbillon C., Pato C., Prehu C., Wajcman H., Marden M.C. Transfer of human alpha- to beta-hemoglobin via its chaperone protein: evidence for a new state. J. Biol. Chem. 2004, 279:36530-36533.
4. Bhutta M.K., Omar A., Yang X. Electronic waste: a growing concern in today[U+05F3]s environment. Econ. Res. Int. 2011, 2011:474230.
5. Bi X., Qu W., Sheng G., Zhang W., Mai B., Chen D., Yu L., Fu J. Polybrominated diphenyl ethers in South China maternal and fetal blood and breast milk. Environ. Pollut 2006, 144(3):1024-1030. (Epub 2006 Mar 24).
6. Bi X., Li Z., Zhuang X., Han Z., Yang W. High levels of antimony in dust from e-waste recycling in southeastern China. Sci. Total Environ. 2011, 409(23):5126-5128.
7. Donmez-Altuntas H., Baran M., Oymak F.S., Hamurcu Z., Imamoglu N., Ozesmi M., et al. Investigation of micronucleus frequencies in lymphocytes of inhabitants environmentally exposed to chrysotile asbestos. Int. J. Environ. Health Res. 2007, 17:45-51.
8. Hua X., Peng L., Zheng L., Qiu Z., Zhang Q. Elevated blood lead levels of children in Guiyu, an electronic waste recycling town in China. Environ. Health Perspect. 2007, 115(7):1113-1117. (2007).
9. Lai M.I., Jiang J., Silver N., Best S., Menzel S. Alpha-haemoglobin stabilising protein is a quantitative trait gene that modifies the phenotype of beta-thalassaemia. Br. J. Haematol. 2006, 133(6):675-682.
10. Leung A.O., Luksemburg W.J., Wong A.S., Wong M.H. Spatial distribution of polybrominated diphenyl ethers and polychlorinated dibenzo-p-dioxins and dibenzofurans in soil and combusted residue at Guiyu, an electronic waste recycling site in southeast China. Environ. Sci. Technol. 2007, 41:2730-2737.
11. Li Y., Richardson J.B., Mark Bricka R., Niu X., Yang H., Li L., et al. Leaching of heavy metals from E-waste in simulated landfill columns. Waste Manag. 2009, 29:2147-2150.
12. Liu Q., Cao J., Li K., Miao X., Li G., et al. Chromosomal aberrations and DNA damage in human populations exposed to the processing of electronics waste. Environ. Sci. Pollut. Res. 2009, 16(3):329-338.
13. Liu X., Tanaka M., Matsui Y. Electrical and electronic waste management in China: progress and the barriers to overcome. Waste Manag. Res. 2006, 24:92-101.
14. Lu X., Chen C., Zhang S., Hou Z., Yang J. Concentration levels and ecological risks of persistent organic pollutants in the surface sediments of tianjin coastal area, China. Sci. World J. 2013, 2013:1-8.
15. Ma J., Cheng J., Wang W., Kunisue T., Wu M., Kannan K. Elevated concentrations of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans and polybrominated diphenyl ethers in hair from workers at an electronic waste recycling facility in eastern China. J. Hazard. Mater. 2011, 186(2-3):1966-1971.
16. Mead N. Contaminants in human milk: weighing the risks against the benefits of breastfeeding. Environ. Health Perspect. 2008, 116(10):A426-A434.
17. Pounds J.G. Effect of lead intoxication on calcium homeostasis and calcium-mediated cell function: a review. Neurotoxicology 1984, 5(3):295-331.
18. Schedes A., Holmer G. A new thiobarbituric acid (TBA) method for determining free malondialdehyde (MDA) and hydroperoxides selectively as a measure of lipid peroxidation. J. Am. Oil Chem. Soc. 1989, 66(6):813-817.
19. Veldhoen M., Hirota K., Westendorf A.M., Buer J., Dumoutier L., Renauld J.C., et al. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature 2008, 453:106-109.
20. Weatherall D.J., Clegg J.B. Inherited haemoglobin disorders: an increasing global health problem. Bull. World Health Organ. 2001, 79:704-712.
21. Yan X., Zheng J., Chen K.H., Yang J., Luo X.J., et al. Dechlorane Plus in serum from e-waste recycling workers: influence of gender and potential isomer-specific metabolism. Environ. Int. 2012, 49:31-37.
22. Yang Q.Y., Qiu X.H., Li R., Liu S.S., Li K.Q., Wang F.F., et al. Exposure to typical persistent organic pollutants from an electronic waste recycling site in Northern China. Chemosphere 2013, 91:205-211.
23. Yuan J., Chen L., Chen D., Guo H., Bi X., Ju Y., et al. Elevated serum polybrominated diphenyl ethers and thyroid-stimulating hormone associated with lymphocytic micronuclei in Chinese workers from an E-waste dismantling site. Environ. Sci. Technol. 2008, 42:2195-2200.
24. Zhu L., Ma B., Hites R.A. Brominated flame retardants in serum from the general population in northern China. Environ. Sci. Technol. 2009, 15(18):6963-6968. (43).