Ongoing pregnancy qualifies best as the primary outcome measure of choice in trials in reproductive medicine: An opinion paper

Fertility and Sterility

Volumn 101, Issue 5, 2014, Pages 1203-1204

  Braakhekke, Miriam ^a   Kamphuis, Esme I ^a   Dancet, Eline A ^a   Mol, Femke ^a   Van Der Veen, Fulco ^a   Mol, Ben W ^b  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

ongoing pregnancy; primary outcome measure; RCT; reproductive medicine; singleton outcome measure

Indexed keywords

CLINICAL TRIAL (TOPIC); EMBRYO TRANSFER; FERTILIZATION IN VITRO; FROZEN EMBRYO TRANSFER; HUMAN; INFERTILITY THERAPY; LIVE BIRTH; OUTCOME ASSESSMENT; PREGNANCY; PREGNANCY RATE; PRIORITY JOURNAL; RANDOM ERROR; REVIEW; TWIN PREGNANCY; DECISION MAKING; EPIDEMIOLOGY; FEMALE; REPRODUCTION; STANDARDS; TREATMENT OUTCOME;

CHOICE BEHAVIOR; CLINICAL TRIALS AS TOPIC; FEMALE; HUMANS; LIVE BIRTH; PREGNANCY; PREGNANCY RATE; REPRODUCTIVE MEDICINE; REPRODUCTIVE TECHNIQUES, ASSISTED; TREATMENT OUTCOME;

EID: 84899654147     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2014.03.047     Document Type: Review

References (8)

1. J.A. Land, and J.L.H. Evers Risks and complications in assisted reproduction techniques: Report of an ESHRE consensus meeting Hum Reprod 18 2003 455 457
2. J.F. Clarke, M.M.E. van Rumste, C.M. Farquhar, N.P. Johnson, B.W.J. Mol, and P. Herbison Measuring outcomes in fertility trials: can we rely on clinical pregnancy rates? Fertil Steril 94 2010 1647 1651
3. D.J. McLernon, K. Harrild, C. Bergh, M.J. Davies, D. de Neubourg, and J.C.M. Dumoulin et al. Clinical effectiveness of elective single versus double embryo transfer: meta-analysis of individual patient data from randomised trials BMJ 341 2010 c6945
4. W.A. Grobman, M.P. Milad, J. Stout, and S.C. Klock Patient perceptions of multiple gestations: an assessment of knowledge and risk aversion Am J Obstet Gynecol 185 2001 920 924
5. M. Van Wely, M. Twisk, B.W. Mol, and F. van der Veen Is twin pregnancy necessarily an adverse outcome of assisted reproductive technologies? Hum Reprod 21 2006 2736 2738
6. E.A. Dancet, T.M. D'Hooghe, F. Van der Veen, P. Bossuyt, W. Sermeus, and B.W. Mol et al. Patient-centered fertility treatment: what is required? Fertil Steril 101 2014 924 926
7. Braakhekke M, Kamphuis EI, Van Rumste MM, Mol F, Van der Veen F, Mol BW. How are fetal and maternal outcomes reported in randomised trials in reproductive medicine? Hum Reprod 2014 Apr 7. [Epub ahead of print].
8. L. Dapuzzo, F.E. Seitz, W.C. Dodson, C. Stetter, A.R. Kunselman, and R.S. Legro Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials Fertil Steril 95 2011 2527 2530