Total synthesis of aculeatins A, B and D and 6-epi-aculeatin D via an asymmetric aldol approach 1

Synthesis (Germany)

Volumn 46, Issue 9, 2014, Pages 1205-1210

  Maram, Lingaiah ^a   Das, Biswanath ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

aculeatins; chiral auxiliary; Crimmins aldol reaction; spirocyclization; stereoselective total synthesis

Indexed keywords

CONDENSATION REACTIONS; KETONES; STEREOSELECTIVITY; SYNTHESIS (CHEMICAL);

ACULEATINS; CHIRAL AUXILIARIES; CRIMMINS ALDOL REACTION; SPIROCYCLIZATION; TOTAL SYNTHESIS;

ISOMERS;

6 EPI ACULEATIN D; ACULEATIN A; ACULEATIN B; ACULEATIN D; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONCENTRATION (PARAMETERS); CYCLIZATION; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IC 50; ISOMER; LUNG CANCER; NONHUMAN; PLASMODIUM; REACTION TIME; TRYPANOSOMA;

EID: 84899643520     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1340866     Document Type: Article

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