Zinc supplementation alleviates diabetic peripheral neuropathy by inhibiting oxidative stress and upregulating metallothionein in peripheral nerves of diabetic rats

Biological Trace Element Research

Volumn 158, Issue 2, 2014, Pages 211-218

  Liu, Fangyao ^a   Ma, Feiyu ^b   Kong, Gengbin ^a   Wu, Kezhou ^a   Deng, Zhihua ^a   Wang, Hu ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b SHANTOU CENTRAL HOSPITAL   (China)

Author keywords

Antioxidant; Experimental diabetic peripheral neuropathy; Metallothionein; Oxidative stress; Zinc

Indexed keywords

MALONALDEHYDE; MESSENGER RNA; METALLOTHIONEIN; METALLOTHIONEIN I; METALLOTHIONEIN II; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; ZINC; ZINC CHLORIDE; STREPTOZOCIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETIC NEUROPATHY; DIET; DIET SUPPLEMENTATION; DRUG EFFECT; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HYPOALGESIA; LIPID PEROXIDATION; MALE; MOTOR NERVE CONDUCTION; NONHUMAN; OXIDATIVE STRESS; PAIN THRESHOLD; PERIPHERAL NERVE; POSTERIOR TIBIAL NERVE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SCIATIC NERVE; TACTILE ALLODYNIA; THERMAL HYPOALGESIA; UPREGULATION; ANIMAL; CHEMICALLY INDUCED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DIETARY SUPPLEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; METALLOTHIONEIN; OXIDATIVE STRESS; PERIPHERAL NERVES; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; UP-REGULATION; ZINC;

EID: 84899636776     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-014-9923-9     Document Type: Article

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