Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the d-mannonate dehydratase subgroup

Biochemistry

Volumn 53, Issue 16, 2014, Pages 2722-2731

  Wichelecki, Daniel J ^a   Balthazor, Bryan M ^a   Chau, Anthony C ^a   Vetting, Matthew W ^b   Fedorov, Alexander A ^b   Fedorov, Elena V ^b   Lukk, Tiit ^a   Patskovsky, Yury V ^b   Stead, Mark B ^b   Hillerich, Brandan S ^b   Seidel, Ronald D ^b   Almo, Steven C ^b   Gerlt, John A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EFFICIENCY; PROTEINS;

CATALYTIC EFFICIENCIES; EXPERIMENTAL CHARACTERIZATION; GENOME SEQUENCING; MANDELATE RACEMASE; PHYSIOLOGICAL FUNCTIONS; PROTEIN SEQUENCE DATABASE; SEQUENCE HOMOLOGY; SUBSTRATE SPECIFICITY;

DEHYDRATION;

D GLUCONATE DEHYDRATASE; D MANNONATE DEHYDRATASE; ENOLASE; GLUCONIC ACID; MANDELATE RACEMASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME PURIFICATION; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; GLUCONATES; HYDRO-LYASES; KINETICS; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHOPYRUVATE HYDRATASE; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUGAR ACIDS;

EID: 84899632710     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500264p     Document Type: Article

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