-
1
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
I.F. Tannock, R. de Wit, and W.R. Berry et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer N Engl J Med 351 2004 1502 1512
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
-
2
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
D.P. Petrylak, C.M. Tangen, and M.H. Hussain et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer N Engl J Med 351 2004 1513 1520
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
-
3
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
J.S. de Bono, S. Oudard, and M. Ozguroglu et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial Lancet 376 2010 1147 1154
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
-
4
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
M.A. Jordan, and L. Wilson Microtubules as a target for anticancer drugs Nat Rev Cancer 4 2004 253 265
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
5
-
-
0031868515
-
Taxanes propagate apoptosis via two cell populations with distinctive cytological and molecular traits
-
P.J. Moos, and F.A. Fitzpatrick Taxanes propagate apoptosis via two cell populations with distinctive cytological and molecular traits Cell Growth Differ 9 1998 687 697
-
(1998)
Cell Growth Differ
, vol.9
, pp. 687-697
-
-
Moos, P.J.1
Fitzpatrick, F.A.2
-
6
-
-
2142656351
-
Regulation of microtubule, apoptosis, and cell cycle-related genes by taxotere in prostate cancer cells analyzed by microarray
-
Y. Li, X. Li, M. Hussain, and F.H. Sarkar Regulation of microtubule, apoptosis, and cell cycle-related genes by taxotere in prostate cancer cells analyzed by microarray Neoplasia 6 2004 158 167
-
(2004)
Neoplasia
, vol.6
, pp. 158-167
-
-
Li, Y.1
Li, X.2
Hussain, M.3
Sarkar, F.H.4
-
8
-
-
80052808323
-
Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer
-
M.S. Darshan, M.S. Loftus, and M. Thadani-Mulero et al. Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer Cancer Res 71 2011 6019 6029
-
(2011)
Cancer Res
, vol.71
, pp. 6019-6029
-
-
Darshan, M.S.1
Loftus, M.S.2
Thadani-Mulero, M.3
-
9
-
-
4644224824
-
Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells
-
I. Brown, K. Shalli, and S.L. McDonald et al. Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells Breast Cancer Res 6 2004 R601 R607
-
(2004)
Breast Cancer Res
, vol.6
-
-
Brown, I.1
Shalli, K.2
McDonald, S.L.3
-
10
-
-
79958228213
-
Resistance to docetaxel-induced apoptosis in prostate cancer cells by p38/p53/p21 signaling
-
L. Gan, J. Wang, H. Xu, and X. Yang Resistance to docetaxel-induced apoptosis in prostate cancer cells by p38/p53/p21 signaling Prostate 71 2011 1158 1166
-
(2011)
Prostate
, vol.71
, pp. 1158-1166
-
-
Gan, L.1
Wang, J.2
Xu, H.3
Yang, X.4
-
11
-
-
34547209343
-
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
-
J.A. McCubrey, L.S. Steelman, and W.H. Chappell et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance Biochim Biophys Acta 1773 2007 1263 1284
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1263-1284
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
-
12
-
-
76149128694
-
CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity
-
D.Z. Qian, B.L. Rademacher, and J. Pittsenbarger et al. CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity Prostate 70 2010 433 442
-
(2010)
Prostate
, vol.70
, pp. 433-442
-
-
Qian, D.Z.1
Rademacher, B.L.2
Pittsenbarger, J.3
-
13
-
-
84869160169
-
Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205
-
M. Puhr, J. Hoefer, and G. Schafer et al. Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205 Am J Pathol 181 2012 2188 2201
-
(2012)
Am J Pathol
, vol.181
, pp. 2188-2201
-
-
Puhr, M.1
Hoefer, J.2
Schafer, G.3
-
14
-
-
84876254445
-
Inhibition of ZEB1 reverses EMT and chemoresistance in docetaxel-resistant human lung adenocarcinoma cell line
-
J. Ren, Y. Chen, H. Song, L. Chen, and R. Wang Inhibition of ZEB1 reverses EMT and chemoresistance in docetaxel-resistant human lung adenocarcinoma cell line J Cell Biochem 114 2013 1395 1403
-
(2013)
J Cell Biochem
, vol.114
, pp. 1395-1403
-
-
Ren, J.1
Chen, Y.2
Song, H.3
Chen, L.4
Wang, R.5
-
15
-
-
0033520806
-
Prostate cancer cell cycle regulators: Response to androgen withdrawal and development of androgen independence
-
D.B. Agus, C. Cordon-Cardo, and W. Fox et al. Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence J Natl Cancer Inst 91 1999 1869 1876
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1869-1876
-
-
Agus, D.B.1
Cordon-Cardo, C.2
Fox, W.3
-
16
-
-
80053231577
-
What is the pathophysiology of a hormone-resistant prostate tumour?
-
B. Tombal What is the pathophysiology of a hormone-resistant prostate tumour? Eur J Cancer 47 2011 S179 S188
-
(2011)
Eur J Cancer
, vol.47
-
-
Tombal, B.1
-
17
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
J.S. de Bono, C.J. Logothetis, and A. Molina et al. Abiraterone and increased survival in metastatic prostate cancer N Engl J Med 364 2011 1995 2005
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
18
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
H.I. Scher, K. Fizazi, and F. Saad et al. Increased survival with enzalutamide in prostate cancer after chemotherapy N Engl J Med 367 2012 1187 1197
-
(2012)
N Engl J Med
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
19
-
-
77952308856
-
Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells
-
M.L. Zhu, and N. Kyprianou Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells FASEB J 24 2010 769 777
-
(2010)
FASEB J
, vol.24
, pp. 769-777
-
-
Zhu, M.L.1
Kyprianou, N.2
-
20
-
-
84862908058
-
Androgen deprivation causes epithelial-mesenchymal transition in the prostate: Implications for androgen-deprivation therapy
-
Y. Sun, B.E. Wang, and K.G. Leong et al. Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy Cancer Res 72 2012 527 536
-
(2012)
Cancer Res
, vol.72
, pp. 527-536
-
-
Sun, Y.1
Wang, B.E.2
Leong, K.G.3
-
21
-
-
69449095278
-
Docetaxel down-regulates the expression of androgen receptor and prostate-specific antigen but not prostate-specific membrane antigen in prostate cancer cell lines: Implications for PSA surrogacy
-
K. Kuroda, H. Liu, and S. Kim et al. Docetaxel down-regulates the expression of androgen receptor and prostate-specific antigen but not prostate-specific membrane antigen in prostate cancer cell lines: implications for PSA surrogacy Prostate 69 2009 1579 1585
-
(2009)
Prostate
, vol.69
, pp. 1579-1585
-
-
Kuroda, K.1
Liu, H.2
Kim, S.3
-
22
-
-
70350532518
-
Inhibition of the androgen receptor as a novel mechanism of taxol chemotherapy in prostate cancer
-
L. Gan, S. Chen, and Y. Wang et al. Inhibition of the androgen receptor as a novel mechanism of taxol chemotherapy in prostate cancer Cancer Res 69 2009 8386 8394
-
(2009)
Cancer Res
, vol.69
, pp. 8386-8394
-
-
Gan, L.1
Chen, S.2
Wang, Y.3
-
23
-
-
78049294167
-
Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer
-
M.L. Zhu, C.M. Horbinski, and M. Garzotto et al. Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer Cancer Res 70 2010 7992 8002
-
(2010)
Cancer Res
, vol.70
, pp. 7992-8002
-
-
Zhu, M.L.1
Horbinski, C.M.2
Garzotto, M.3
-
24
-
-
0031024251
-
Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor
-
L.E. Heisler, A. Evangelou, and A.M. Lew et al. Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor Mol Cell Endocrinol 126 1997 59 73
-
(1997)
Mol Cell Endocrinol
, vol.126
, pp. 59-73
-
-
Heisler, L.E.1
Evangelou, A.2
Lew, A.M.3
-
25
-
-
25444477562
-
Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells
-
R.B. Montgomery, M. Bonham, and P.S. Nelson et al. Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells Prostate 65 2005 141 150
-
(2005)
Prostate
, vol.65
, pp. 141-150
-
-
Montgomery, R.B.1
Bonham, M.2
Nelson, P.S.3
-
26
-
-
33750034898
-
Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells
-
I.V. Litvinov, D.J. Vander Griend, and L. Antony et al. Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells Proc Natl Acad Sci U S A 103 2006 15085 15090
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15085-15090
-
-
Litvinov, I.V.1
Vander Griend, D.J.2
Antony, L.3
-
27
-
-
77951518711
-
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate
-
A.H. Reid, G. Attard, and D.C. Danila et al. Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate J Clin Oncol 28 2010 1489 1495
-
(2010)
J Clin Oncol
, vol.28
, pp. 1489-1495
-
-
Reid, A.H.1
Attard, G.2
Danila, D.C.3
-
28
-
-
84866909021
-
Antitumour activity of docetaxel following treatment with the CYP17A1 inhibitor abiraterone: Clinical evidence for cross-resistance?
-
J. Mezynski, C. Pezaro, and D. Bianchini et al. Antitumour activity of docetaxel following treatment with the CYP17A1 inhibitor abiraterone: clinical evidence for cross-resistance? Ann Oncol 23 2012 2943 2947
-
(2012)
Ann Oncol
, vol.23
, pp. 2943-2947
-
-
Mezynski, J.1
Pezaro, C.2
Bianchini, D.3
-
29
-
-
22344446693
-
Neoadjuvant docetaxel before radical prostatectomy in patients with high-risk localized prostate cancer
-
P.G. Febbo, J.P. Richie, and D.J. George et al. Neoadjuvant docetaxel before radical prostatectomy in patients with high-risk localized prostate cancer Clin Cancer Res 11 2005 5233 5240
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5233-5240
-
-
Febbo, P.G.1
Richie, J.P.2
George, D.J.3
-
30
-
-
84873095322
-
Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): A randomised, open-label, phase 3 trial
-
G. Gravis, K. Fizazi, and F. Joly et al. Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial Lancet Oncol 14 2013 149 158
-
(2013)
Lancet Oncol
, vol.14
, pp. 149-158
-
-
Gravis, G.1
Fizazi, K.2
Joly, F.3
-
31
-
-
84866948935
-
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: Final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
-
K. Fizazi, H.I. Scher, and A. Molina et al. Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study Lancet Oncol 13 2012 983 992
-
(2012)
Lancet Oncol
, vol.13
, pp. 983-992
-
-
Fizazi, K.1
Scher, H.I.2
Molina, A.3
-
32
-
-
84871203074
-
Exploratory analysis of survival benefit and prior docetaxel (D) treatment in COU-AA-301, a phase III study of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) [abstract 15]
-
K.N. Chi Exploratory analysis of survival benefit and prior docetaxel (D) treatment in COU-AA-301, a phase III study of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) [abstract 15] J Clin Oncol 2012 30
-
(2012)
J Clin Oncol
, pp. 30
-
-
Chi, K.N.1
-
33
-
-
84867572373
-
Response to abiraterone acetate in the postchemotherapy setting in patients with castration-resistant prostate cancer whose disease progresses early on docetaxel [abstract 17]
-
D. Mukherji, C.J. Pezaro, D. Bianchini, A. Zivi, and J.S. de Bono Response to abiraterone acetate in the postchemotherapy setting in patients with castration-resistant prostate cancer whose disease progresses early on docetaxel [abstract 17] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Mukherji, D.1
Pezaro, C.J.2
Bianchini, D.3
Zivi, A.4
De Bono, J.S.5
-
34
-
-
84882789820
-
Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100)
-
Y. Loriot, D. Bianchini, and E. Ileana et al. Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Ann Oncol 24 2013 1807 1812
-
(2013)
Ann Oncol
, vol.24
, pp. 1807-1812
-
-
Loriot, Y.1
Bianchini, D.2
Ileana, E.3
-
35
-
-
84882799782
-
Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide
-
K.L. Noonan, S. North, and R.L. Bitting et al. Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Ann Oncol 24 2013 1802 1807
-
(2013)
Ann Oncol
, vol.24
, pp. 1802-1807
-
-
Noonan, K.L.1
North, S.2
Bitting, R.L.3
-
36
-
-
84903180632
-
Efficacy of cabazitaxel and its relationship with predictors of poor response to second hormonal therapies in metastatic castration-resistant prostate cancer (mCRPC) [abstract 137]
-
S. Oudard, F. Mercier, and A. Flechon et al. Efficacy of cabazitaxel and its relationship with predictors of poor response to second hormonal therapies in metastatic castration-resistant prostate cancer (mCRPC) [abstract 137] J Clin Oncol 31 Suppl 6 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Oudard, S.1
Mercier, F.2
Flechon, A.3
-
37
-
-
84887952383
-
Response to cabazitaxel in CRPC patients previously treated with docetaxel and abiraterone acetate [abstract 155]
-
J.P. Pezaro, S. Le Moulec, and L. Albiges et al. Response to cabazitaxel in CRPC patients previously treated with docetaxel and abiraterone acetate [abstract 155] J Clin Oncol 31 Suppl 6 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Pezaro, J.P.1
Le Moulec, S.2
Albiges, L.3
-
38
-
-
84891833046
-
Prognostic factors of survival in patients with metastatic castration resistant prostate cancer (mCRPC) treated with cabazitaxel: Sequencing might matter [abstract 5063]
-
A. Angelergues, D. Maillet, and A. Flechon et al. Prognostic factors of survival in patients with metastatic castration resistant prostate cancer (mCRPC) treated with cabazitaxel: sequencing might matter [abstract 5063] J Clin Oncol 31 Suppl 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
Angelergues, A.1
Maillet, D.2
Flechon, A.3
-
39
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
C.J. Ryan, M.R. Smith, and J.S. de Bono et al. Abiraterone in metastatic prostate cancer without previous chemotherapy N Engl J Med 368 2013 138 148
-
(2013)
N Engl J Med
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
-
40
-
-
84879901733
-
Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy [abstract 5]
-
D.E. Rathkopf, M.R. Smith, and J.S. De Bono et al. Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy [abstract 5] J Clin Oncol 31 Suppl 6 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Rathkopf, D.E.1
Smith, M.R.2
De Bono, J.S.3
-
41
-
-
84867579919
-
An ambispective observational study in the safety and efficacy of abiraterone acetate in the French temporary authorizations for use (ATU): Predictive parameters of response [abstract 149]
-
D. Azria, C. Massard, and D. Tosi et al. An ambispective observational study in the safety and efficacy of abiraterone acetate in the French temporary authorizations for use (ATU): predictive parameters of response [abstract 149] J Clin Oncol 30 Suppl 5 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL. 5
-
-
Azria, D.1
Massard, C.2
Tosi, D.3
-
42
-
-
84865845529
-
Personalizing treatment in patients with castrate-resistant prostate cancer: A study of predictive factors for secondary endocrine therapies activity [abstract 213]
-
Y. Loriot, C. Massard, and L. Albiges et al. Personalizing treatment in patients with castrate-resistant prostate cancer: a study of predictive factors for secondary endocrine therapies activity [abstract 213] J Clin Oncol 30 Suppl 5 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL. 5
-
-
Loriot, Y.1
Massard, C.2
Albiges, L.3
-
43
-
-
84899539011
-
Impact of cabazitaxel (Cbz) + prednisone (P; CbzP) on overall survival (OS) at 2 yrs and in patients (pts) with aggressive disease: Post-hoc analyses of TROPIC trial [conference abstract]
-
S. Oudard, J.S. De Bono, and M. Ozguroglu et al. Impact of cabazitaxel (Cbz) + prednisone (P; CbzP) on overall survival (OS) at 2 yrs and in patients (pts) with aggressive disease: post-hoc analyses of TROPIC trial [conference abstract] Ann Oncol 23 2012 ix307
-
(2012)
Ann Oncol
, vol.23
, pp. 307
-
-
Oudard, S.1
De Bono, J.S.2
Ozguroglu, M.3
-
44
-
-
84899570351
-
The initial biopsy Gleason score as a predictive marker for docetaxel survival benefit in patients with prostate cancer: Data from the TAX 327 study [abstract 44]
-
R. van Soest, E. de Morrée, and L. Shen et al. The initial biopsy Gleason score as a predictive marker for docetaxel survival benefit in patients with prostate cancer: data from the TAX 327 study [abstract 44] J Clin Oncol 31 Suppl 6 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Van Soest, R.1
De Morrée, E.2
Shen, L.3
|