Does limb preconditioning reduce pain after total knee arthroplasty? A randomized, double-blind study

Clinical Orthopaedics and Related Research

Volumn 472, Issue 5, 2014, Pages 1467-1474

  Memtsoudis, Stavros G ^a   Stundner, Ottokar ^b   Yoo, Daniel ^a   Gonzalez Della Valle, Alejandro ^a   Boettner, Friedrich ^a   Bombardieri, Anna Maria ^a   Jules Elysee, Kethy ^a   Poultsides, Lazaros ^a   Ma, Yan ^a   Sculco, Thomas P ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; EXERCISE; FEMALE; HOSPITALIZATION; HUMAN; ISCHEMIC PRECONDITIONING; LENGTH OF STAY; MALE; OXYGENATION; PHYSIOTHERAPY; POSTOPERATIVE INFLAMMATION; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REST; TOTAL KNEE REPLACEMENT; TOURNIQUET;

AGED; ANALGESICS; ANTITHROMBIN III; ARTHROPLASTY, REPLACEMENT, KNEE; BIOLOGICAL MARKERS; BLOOD COAGULATION; DOUBLE-BLIND METHOD; EXERCISE; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; ISCHEMIC PRECONDITIONING; LENGTH OF STAY; LOWER EXTREMITY; MALE; MIDDLE AGED; NEW YORK CITY; PAIN MANAGEMENT; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PROSPECTIVE STUDIES; PROTHROMBIN; RECOVERY OF FUNCTION; REGIONAL BLOOD FLOW; SYNOVIAL FLUID; TIME FACTORS; TOURNIQUETS; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84899544963     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-013-3106-4     Document Type: Conference Paper

References (23)

1. Aglietti P, Baldini A, Vena LM, Abbate R, Fedi S, Falciani M. Effect of tourniquet use on activation of coagulation in total knee replacement. Clin Orthop Relat Res. 2000;371:169-177. (Pubitemid 30090835)
2. American Society of Anesthesiologists. ASA Physical Status Classification System. Available at: www.asahq.org/Home/For-Members/Clinical-Information/ASA- Physical-Status-Classification-System. Accessed July 2012.
3. Bagry H, De la Cuadra Fontaine JC, Asenjo JF, Bracco D, Carli F. Effect of a continuous peripheral nerve block on the inflammatory response in knee arthroplasty. Reg Anesth Pain Med. 2008;33:17-23. (Pubitemid 350266398)
4. Chang CB, Cho WS. Pain management protocols, peri-operative pain and patient satisfaction after total knee replacement: a multicentre study. J Bone Joint Surg Br. 2012;94:1511-1516.
5. Duellman TJ, Gaffigan C, Milbrandt JC, Allan DG. Multi-modal, pre-emptive analgesia decreases the length of hospital stay following total joint arthroplasty. Orthopedics . 2009;32:167.
6. Farrar JT, Portenoy RK, Berlin JA, Kinman JL, Strom BL. Defining the clinically important difference in pain outcome measures. Pain. 2000;88:287-294.
7. Feng Y, Ju H, Yang B, An H. Effects of a selective cyclooxygenase-2 inhibitor on postoperative inflammatory reaction and pain after total knee replacement. J Pain. 2008;9:45-52. (Pubitemid 350309729)
8. Flaherty SA. Pain measurement tools for clinical practice and research. AANA J. 1996;64:133-140.
9. Harkin DW, Barros D'Sa AA, McCallion K, Hoper M, Campbell FC. Ischemic preconditioning before lower limb ischemia-reperfusion protects against acute lung injury. J Vasc Surg. 2002;35:1264-1273. (Pubitemid 44718533)
10. Hughes SF, Hendricks BD, Edwards DR, Bastawrous SS, Roberts GE, Middleton JF. Mild episodes of tourniquet-induced forearm ischaemia-reperfusion injury results in leukocyte activation and changes in inflammatory and coagulation markers. J Inflamm (Lond). 2007;4:12.
11. Lippi G, Cervellin G, Franchini M, Favaloro EJ. Biochemical markers for the diagnosis of venous thromboembolism: the past, present and future. J Thromb Thrombolysis. 2010;30:459-471.
12. Ma Y, Mazumdar M, Memtsoudis SG. Beyond repeated-measures analysis of variance: advanced statistical methods for the analysis of longitudinal data in anesthesia research. Reg Anesth Pain Med. 2012;37:99-105.
13. Martinez V, Fletcher D, Bouhassira D, Sessler DI, Chauvin M. The evolution of primary hyperalgesia in orthopedic surgery: quantitative sensory testing and clinical evaluation before and after total knee arthroplasty. Anesth Analg. 2007;105:815-821. (Pubitemid 47300865)
14. Memtsoudis SG, Valle AG, Jules-Elysse K, Poultsides L, Reid S, Starcher B, Ma Y, Sculco TP. Perioperative inflammatory response in total knee arthroplasty patients: impact of limb preconditioning. Reg Anesth Pain Med. 2010;35:412-416.
15. Murry CE, Richard VJ, Reimer KA, Jennings RB. Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode. Circ Res. 1990;66:913-931. (Pubitemid 20126423)
16. Orban JC, Levraut J, Gindre S, Deroche D, Schlatterer B, Ichai C, Grimaud D. Effects of acetylcysteine and ischaemic preconditioning on muscular function and postoperative pain after orthopaedic surgery using a pneumatic tourniquet. Eur J Anaesthesiol. 2006;23:1025-1030. (Pubitemid 44622930)
17. Páramo JA. Prothrombin fragments in cardiovascular disease. Adv Clin Chem. 2010;51:1-23.
18. ReikeråsO,ClementsenT. Time course of thrombosis and fibrinolysis in total knee arthroplasty with tourniquet application. Local versus systemic activations. J Thromb Thrombolysis. 2009;28:425-428.
19. Schoen M, Rotter R, Gierer P, Gradl G, Strauss U, Jonas L, Mittlmeier T, Vollmar B. Ischemic preconditioning prevents skeletal muscle tissue injury, but not nerve lesion upon tourniquet- induced ischemia. J Trauma . 2007;63:788-797. (Pubitemid 350287296)
20. Soller BR, Ryan KL, Rickards CA, Cooke WH, Yang Y, Soyemi OO, Crookes BA, Heard SO, Convertino VA. Oxygen saturation determined from deep muscle, not thenar tissue, is an early indicator of central hypovolemia in humans. Crit Care Med. 2008;36:176-182.
21. Vince KG. The stiff total knee arthroplasty: causes and cures. J Bone Joint Surg Br. 2012;94:103-111.
22. YaDeau JT, Cahill JB, Zawadsky MW, Sharrock NE, Bottner F, Morelli CM, Kahn RL, Sculco TP. The effects of femoral nerve blockade in conjunction with epidural analgesia after total knee arthroplasty. Anesth Analg. 2005;101: 891-895.
23. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42:121-130.