Thermo-responsive and biocompatible diblock copolymers prepared via reversible addition-fragmentation chain transfer (RAFT) radical polymerization

Polymers

Volumn 6, Issue 3, 2014, Pages 846-859

  Fukuda, Kenichi ^a   Enomoto, Ryusuke ^a   Ishihara, Kazuhiko ^b   Morishima, Yotaro ^c   Yusa, Shin Ichi ^a  

^a UNIVERSITY OF HYOGO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c FUKUI UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

Block copolymers; Critical aggregation temperature; Micelles; RAFT polymerization; Water soluble polymers

Indexed keywords

ATOM TRANSFER RADICAL POLYMERIZATION; BIOCOMPATIBILITY; BLOCK COPOLYMERS; HYDROPHOBICITY; LIVING POLYMERIZATION; MICELLES; MOLECULES; POLYMERS;

CONTROLLED RADICAL POLYMERIZATION; CRITICAL AGGREGATION TEMPERATURE; FLUORESCENCE PROBES; HYDRODYNAMIC RADIUS; PHOSPHORYLCHOLINE; RAFT POLYMERIZATION; REVERSIBLE ADDITION FRAGMENTATION CHAIN TRANSFER (RAFT); WATERSOLUBLE POLYMERS;

FREE RADICAL POLYMERIZATION;

EID: 84899513880     PISSN: None     EISSN: 20734360     Source Type: Journal    
DOI: 10.3390/polym6030846     Document Type: Article

References (17)

1. Inoue, Y.; Nakanishi, T.; Ishihara, K. Adhesion force of proteins against hydrophilic polymer brush surfaces. React. Funct. Polym. 2011, 71, 350-355.
2. Ueda, T.; Oshida, H.; Kurita, K.; Ishihara, K.; Nakabayashi, N. Preparation of 2-methacryloyloxyethyl phosphorylcholine copolymers with alkyl methacrylates and their blood compatibility. Polym. J. 1992, 24, 1259-1269.
3. Plate, N.A.; Lebedeva, T.L.; Valuev, L.I. Lower critical solution temperature in aqueous solutions of N-alkyl-substituted polyacrylamides. Polym. J. 1999, 31, 21-27.
4. Heskins, M.; Guillet, J.E. Solution properties of poly(N-isopropylacrylamide). J. Macromol. Sci. Chem. 1968, 2, 1441-1455.
5. Wu, C.; Zhou, S. Laser light scattering study of the phase transition of poly(N-isopropylacrylamide) in water. 1. Single chain. Macromolecules 1995, 28, 8381-8387.
6. Idziak, I.; Avoce, D.; Lessard, D.; Gravel, D.; Zhu, X.X. Thermosensitivity of aqueous solutions of poly(N, N-diethylacrylamide). Macromolecules 1999, 32, 1260-1263.
7. Schild, H.G. Poly(N-isopropylacrylamide): Experiment, theory and application. Prog. Polym. Sci. 1992, 17, 163-249.
8. Yu, B.; Lowe, A.B.; Ishihara, K. RAFT synthesis and stimulus-induced self-assembly in water of copolymers based on the biocompatible monomer 2-(methacryloyloxy) ethyl phosphorylcholine. Biomacromolecules 2009, 10, 950-958.
9. Ishihara, K.; Ueda, T.; Nakabayashi, N. Preparation of phospholipid polylners and their properties as polymer hydrogel membranes. Polym. J. 1990, 22, 355-360.
10. Mitsukami, Y.; Donovan, M.S.; Lowe, A.B.; McCormick, C.L. Water-soluble polymers. 81. Direct synthesis of hydrophilic styrenic-based homopolymers and block copolymers in aqueous solution via RAFT. Macromolecules 2001, 34, 2248-2256.
11. Yusa, S.; Fukuda, K.; Yamamoto, T.; Ishihara, K.; Morishima, Y. Synthesis of well-defined amphiphilic block copolymers having phospholipid polymer sequences as a novel biocompatible polymer micelle reagent. Biomacromolecules 2005, 6, 663-670.
12. Yusa, S.; Kamachi, M.; Morishima, Y. Hydrophobic self-association of cholesterol moieties covalently linked to polyelectrolytes: Effect of spacer bond. Langmuir 1998, 14, 6059-6067.
13. Tang, Y.; Liu, S.Y.; Armes, S.P.; Billingham, N.C. Solubilization and controlled release of a hydrophobic drug using novel micelle-forming ABC triblock copolymers. Biomacromolecules 2003, 4, 1636-1645.
14. Donovan, M.S.; Lowe, A.B.; Sumerlin, B.S.; McCormick, C.L. RAFT polymerization of N, N-dimethylacrylamide utilizing novel chain transfer agents tailored for high reinitiation efficiency and structural control. Macromolecules 2002, 35, 4123-4132.
15. Yusa, S.; Sakakibara, A.; Yamamoto, T.; Morishima, Y. Reversible pH-induced formation and disruption of unimolecular micelles of an amphiphilic polyelectrolyte. Macromolecules 2002, 35, 5243-5249.
16. Yusa, S.; Konishi, Y.; Mitsukami, Y.; Yamamoto, T.; Morishima, Y. pH-responsive micellization of amine-containing cationic diblock copolymers prepared by reversible addition-Fragmentation chain transfer (RAFT) radical polymerization. Polym. J. 2005, 37, 480-488.
17. Yokoyama, M.; Kwon, G.S.; Okano, T.; Sakurai, Y.; Seto, T.; Kataoka, K. Preparation of micelle-forming polymer-drug conjugates. Bioconjugate Chem. 1992, 3, 295-301.