Effectiveness and preclinical safety profile of doxycycline to be used "off-Label" to induce therapeutic transgene expression in a phase i clinical trial for glioma

Human Gene Therapy Clinical Development

Volumn 24, Issue 3, 2013, Pages 116-126

  Vanderveen, Nathan ^a   Paran, Christopher ^a   Krasinkiewicz, Jonathan ^a   Zhao, Lili ^b   Palmer, Donna ^c   Hervey Jumper, Shawn ^a   Ng, Philip ^c   Lowenstein, Pedro R ^a   Castro, Maria G ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BRAIN NEOPLASMS; CLINICAL TRIALS, PHASE I AS TOPIC; DOXYCYCLINE; DRUG EVALUATION, PRECLINICAL; FMS-LIKE TYROSINE KINASE 3; GENE EXPRESSION; GENETIC THERAPY; GLIOBLASTOMA; MALE; RATS; RATS, INBRED LEW; TRANSGENES;

EID: 84899503299     PISSN: 23248637     EISSN: 23248645     Source Type: Journal    
DOI: 10.1089/humc.2013.139     Document Type: Article

References (38)