A randomized, controlled, double-blind crossover study on the effects of 1-l infusions of 6% hydroxyethyl starch suspended in 0.9% saline (Voluven) and a balanced solution (Plasma Volume Redibag) on blood volume, renal blood flow velocity, and renal cortical tissue perfusion in healthy volunteers

Annals of Surgery

Volumn 259, Issue 5, 2014, Pages 881-887

  Chowdhury, Abeed H ^a   Cox, Eleanor F ^b   Francis, Susan T ^b   Lobo, Dileep N ^a  

^a Division of Gastrointestinal Surgery Nottingham Digestive Diseases Centre National Institute for Health Research Biomedical Research Unit Nottingham University Hospitals ^*  (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

0.9 saline; 6 hydroxyethyl starch; balanced crystalloids; hyperchloremia; magnetic resonance imaging; renal tissue perfusion

Indexed keywords

BALANCED SALT SOLUTION; CHLORIDE; CREATININE; HETASTARCH; ION; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PLASMA VOLUME REDIBAG; UNCLASSIFIED DRUG;

ADULT; ANTHROPOMETRY; ARTICLE; BLOOD FLOW VELOCITY; BLOOD SAMPLING; BLOOD VOLUME; CHLORIDE BLOOD LEVEL; COMPARATIVE TOXICOLOGY; CONTROLLED STUDY; CREATININE URINE LEVEL; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; HEMOCONCENTRATION; HUMAN; HUMAN EXPERIMENT; HYPERCHLOREMIA; INFUSION RATE; ION MONITORING; KIDNEY PERFUSION; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; PROTEIN URINE LEVEL; RANDOMIZED CONTROLLED TRIAL; RENAL BLOOD FLOW VELOCITY; RENAL CORTICAL TISSUE PERFUSION; TISSUE PERFUSION;

ACETATES; BLOOD VOLUME; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FOLLOW-UP STUDIES; HEALTHY VOLUNTEERS; HUMANS; HYDROXYETHYL STARCH DERIVATIVES; INFUSIONS, INTRAVENOUS; KIDNEY CORTEX; MAGNETIC RESONANCE IMAGING; MALE; MINERALS; PLASMA SUBSTITUTES; REGIONAL BLOOD FLOW; RENAL ARTERY; RENAL CIRCULATION; SODIUM CHLORIDE; YOUNG ADULT;

EID: 84899493749     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0000000000000324     Document Type: Article

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