Predictors of long-term recurrent vascular events after ischemic stroke at young age: The Italian project on stroke in young adults

Circulation

Volumn 129, Issue 16, 2014, Pages 1668-1676

  Pezzini, Alessandro ^a   Grassi, Mario ^b   Lodigiani, Corrado ^c   Patella, Rosalba ^d   Gandolfo, Carlo ^e   Zini, Andrea ^f   Delodovici, Maria Luisa ^g   Paciaroni, Maurizio ^h   Del Sette, Massimo ^d   Toriello, Antonella ⁱ   Musolino, Rossella ^d,j   Calabrò, Rocco Salvatore ^k   Bovi, Paolo ^l   Adami, Alessandro ^m   Silvestrelli, Giorgio ⁿ   Sessa, Maria ^o   Cavallini, Anna ^p   Marcheselli, Simona ^c   Bonifati, Domenico Marco ^q   Checcarelli, Nicoletta ^r   Tancredi, Lucia ^s   Chiti, Alberto ^t   Del Zotto, Elisabetta ^u   Spalloni, Alessandra ^a   Giossi, Alessia ^v   Volonghi, Irene ^v   Costa, Paolo ^a   Giacalone, Giacomo ^o   Ferrazzi, Paola ^a   Poli, Loris ^a   Morotti, Andrea ^a   Rasura, Maurizia ^a   Simone, Anna Maria ^f   Gamba, Massimo ^p   Cerrato, Paolo ^x   Micieli, Giuseppe ^w   Melis, Maurizio ^y   Massucco, Davide ^e   De Giuli, Valeria ^a   Iacoviello, Licia ^p   Padovani, Alessandro ^a   more..

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

^f Nuovo Ospedale S Agostino   (Italy)

^g UNIVERSITY OF INSUBRIA   (Italy)

^h UNIVERSITY OF PERUGIA   (Italy)

ⁱ UNIVERSITY HOSPITAL SAN GIOVANNI DI DIO E RUGGI D ARAGONA   (Italy)

^j UNIVERSITY OF MESSINA   (Italy)

^k IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^l UNIVERSITY HOSPITAL OF VERONA   (Italy)

^m Stroke Center   (Italy)

ⁿ CARLO POMA HOSPITAL   (Italy)

^o Neurology and Stroke Unit Neurosciences Department AO Ospedale Niguarda Ca Granda   (Italy)

^p IRCCS   (Italy)

^q SANTA CHIARA HOSPITAL   (Italy)

^r VALDUCE HOSPITAL   (Italy)

^s SANT ANNA HOSPITAL   (Italy)

^t UNIVERSITY HOSPITAL OF PISA   (Italy)

^u IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^v UO Neurologia   (Italy)

^w Stroke Unit   (Italy)

^x UNIVERSITY OF TURIN   (Italy)

^y BROTZU HOSPITAL   (Italy)

more..

Author keywords

brain ischemia; prognosis; stroke

Indexed keywords

ANTIHYPERTENSIVE AGENT; ANTITHROMBOCYTIC AGENT; PHOSPHOLIPID ANTIBODY;

ADULT; ARTERY THROMBOSIS; ARTICLE; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; FAMILY HISTORY; FEMALE; FOLLOW UP; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MIGRAINE WITH AURA; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RECURRENCE RISK; RECURRENT DISEASE; RISK FACTOR; SCORING SYSTEM; TRANSIENT ISCHEMIC ATTACK; YOUNG ADULT;

BRAIN ISCHEMIA; PROGNOSIS; STROKE;

ADULT; AGE FACTORS; BRAIN ISCHEMIA; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; ITALY; MALE; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RECURRENCE; STROKE; TIME FACTORS; YOUNG ADULT;

EID: 84899493245     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.113.005663     Document Type: Article

References (41)

1. Touzé E, Varenne O, Chatellier G, Peyrard S, Rothwell PM, Mas JL. Risk of myocardial infarction and vascular death after transient ischemic attack and ischemic stroke: a systematic review and meta-analysis. Stroke. 2005;36:2748-2755.
2. Varona JF. Long-term prognosis of ischemic stroke in young adults. Stroke Res Treat. 2011;879817.
3. Leys D, Debette S. Epidemiology of ischemic stroke in young adults. In: Pezzini A, Padovani A, eds. Cerebral Ischemia in Young Adults: Pathogenic and Clinical Perspectives. New York: Nova Science Publishers; 2009:1-24.
4. Pezzini A, Grassi M, Lodigiani C, Patella R, Gandolfo C, Casoni F, Musolino R, Calabrò RS, Bovi P, Adami A, DeLodovici ML, Del Zotto E, Rota LL, Rasura M, Del Sette M, Giossi A, Volonghi I, Zini A, Cerrato P, Costa P, Magoni M, Iacoviello L, Padovani A, on behalf of the Italian Project on Stroke in Young Adults (IPSYS) Investigators. Predictors of migraine subtypes in young adults with ischemic stroke. The Italian Project on Stroke in Young Adults (IPSYS). Stroke. 2011;42:17-21.
5. Aho K, Harmsen P, Hatano S, Marquardsen J, Smirnov VE, Strasser T. Cerebrovascular disease in the community: results of a WHO collaborative study. Bull World Health Organ. 1980;58:113-130. (Pubitemid 10013261)
6. Headache Classification Subcommittee of the International Headache Society. The international classification of headache disorders. Cephalalgia. 2004;24(suppl 1):24-36.
7. Brandt JT, Triplett DA, Alving B, Scharrer I. Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH. Thromb Haemost. 1995;74:1185-1190.
8. Harris EN, Pierangeli SS. Revisiting the anticardiolipin test and its standardization. Lupus. 2002;11:269-75. (Pubitemid 34627428)
9. Reber G, Tincani A, Sanmarco M, de Moerloose P, Boffa MC. Proposals for the measurement of anti-beta2-glycoprotein I antibodies. Standardization group of the European Forum on Antiphospholipid Antibodies. J Thromb Haemost. 2004;2:1860-1862. (Pubitemid 40192732)
10. Johnson CJ, Kittner SJ, McCarter RJ, Sloan MA, Stern BJ, Buchholz D, Price TR. Interrater reliability of an etiologic classification of ischemic stroke. Stroke. 1995;26:46-51.
11. Morris DL, Kritchevsky SB, Davis CE. Serum carotenoids and coronary heart disease: The Lipid Research Clinics Coronary Primary Prevention Trial and Follow-up study. JAMA. 1994;272:1439-1441. (Pubitemid 24328387)
12. Landi G. Clinical diagnosis of transient ischaemic attacks. Lancet. 1992; 339: 402-405.
13. European Stroke Initiative recommendations for stroke management. European Stroke Council, European Neurological Society and European Federation of Neurological Societies. Cerebrovasc Dis. 2000;10:335-351.
14. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Ass. 1958;53:457-481.
15. Tibshirani R. The lasso method for variable selection in the Cox model. Stat Med. 1997;16:385-395. (Pubitemid 27073009)
16. Hastie T, Tibshirani RFJ. The Elements of Statistical Learning. New York, NY: Springer; 2001.
17. Harrell FE, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med. 1996;15:361-387. (Pubitemid 26072233)
18. Hung H, Chang C. Estimation methods for time-dependent AUC with survival data. Can J Stat. 2010;38:8-26.
19. Uno H, Cai T, Pencina MJ, D'Agostino RB, Wei LJ. On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data. Stat Med. 2011;30:1105-1116.
20. Gerds T, Schumacher M. Efron-type measures of prediction error for survival analysis. Biometrics. 2007;63:1283-1287. (Pubitemid 350212588)
21. Gerds TA, Cai T, Schumacher M. The performance of risk prediction models. Biom J. 2008;50:457-479.
22. Kissela BM, Khoury JC, Alwell K, Moomaw CJ, Woo D, Adeoye O, Flaherty ML, Khatri P, Ferioli S, De Los Rios La Rosa F, Broderick JP, Kleindorfer DO. Age at stroke. Temporal trends in stroke incidence in a large, biracial population. Neurology. 2012;79:1781-1787.
23. Putaala J, Haapaniemi E, Metso AJ, Metso TM, Artto V, Kaste M, Tatlisumak T. Recurrent of ischemic events in young adults after first-ever ischemic stroke. Ann Neurol. 2010;68:661-671.
24. Rutten-Jacobs LCA, Maaijwee NAM, Arntz RM, Schoonderwaldt HC, Dorresteijn LD, van der Vlugt MJ, van Dijk EJ, de Leeuw FE. Long-term risk of recurrent vascular events after young stroke: the FUTURE study. Ann Neurol. 2013;74:592-601.
25. Putaala J, Haapaniemi E, Kaste M, Tatlisumak T. How does number of risk factors affect prognosis in young patients with ischemic stroke? Stroke. 2012;43:356-361.
26. Von Sarnowski B, Putaala J, Grittner U, Gaertner B, Schminke U, Curtze S, Huber R, Tanislav C, Lichy C, Demarin V, Basic-Kes V, Ringelstein EB, Neumann-Haefelin T, Enzinger C, Fazekas F, Rothwell PM, Dichgans M, Jungehulsing GJ, Heuschmann PU, Kaps M, Norrving B, Rolfs A, Kessler C, Tatlisumak T, on behalf of the Sifap1 investigators. Lifestyle risk factors for ischemic stroke and transient ischemic attack in young adults in the Stroke in Young Fabry Patients study. Stroke. 2013;44:119-125.
27. Bousser MG, Welch KMA. Relation between migraine and stroke. Lancet Neurol. 2005;4:533-542. (Pubitemid 41139975)
28. Ji R, Schwamm LH, Pervez MA, Singhal AB. Ischemic stroke and transient ischemic attack in young adults. Risk factors, diagnostic yield, neuroimaging, and thrombolysis. JAMA Neurol. 2013;70:51-57.
29. Nedeltchev K, dar Maur TA, Georgiadis D, Arnold M, Caso V, Mattle HP, Schroth G, Remonda L, Sturzenegger M, Fischer U, Baumgartner RW. Ischemic stroke in young adults: predictors of outcome and recurrence. J Neurol Neurosurg Psychiatry. 2005;76:191-195. (Pubitemid 40143706)
30. Camerlingo M, Casto L, Censori B, Ferraro B, Caverni L, Manara O, Finazzi G, Radice E, Drago G, De Tommasi SM, Gotti E, Barbui T, Mamoli A. Recurrence after first cerebral infarction in young adults. Acta Neurol Scand. 2000;102:87-93. (Pubitemid 30469501)
31. Kapelle LJ, Adams HP, Heffner ML, Torner JC, Gomez F, Biller J. Prognosis of young adults with ischemic stroke. A long-term follow-up study assessing recurrent vascular events and functional outcome in the Iowa Registry of Stroke in Young Adults. Stroke. 1994;25:1360-1365. (Pubitemid 24198580)
32. Spengos K, Vemmos K. Risk factors, etiology, and outcome of first-ever ischemic stroke in young adults aged 15 to 45-the Athens Young Stroke Registry. Eur J Neurol. 2010;17:1358-1364.
33. Naess H, Nyland HI, Thomassen L, Aarseth J, Myhr KM. Long-term outcome of cerebral infarction in young adults. Acta Neurol Scand. 2004;110:107-112. (Pubitemid 39044047)
34. Ferro JM, Crespo M. Prognosis after transient ischemic attack and ischemic stroke in young adults. Stroke. 1994;25:1611-1616. (Pubitemid 24233967)
35. Leys D, Bandu L, Hénon H, Lucas C, Mounier-Vehier F, Rondepierre P, Godefroy O. Clinical outcome in 287 consecutive young adults (15 to 45 years) with ischemic stroke. Neurology. 2002;59:26-33. (Pubitemid 34742790)
36. Gioia LC, Tollard E, Dubuc V, Lanthier S, Deschaintre Y, Chagnon M, Poppe AY. Silent ischemic lesions in young adults with first stroke are associated with recurrent stroke. Neurology. 2012;79:1208-1214.
37. Flossman E, Schulz UGR, Rothwell PM. Systematic review of methods and results of studies of the genetic epidemiology of ischemic stroke. Stroke. 2004;35:212-227. (Pubitemid 38057622)
38. Hong KS, Yegiaian S, Lee M, Lee J, Saver JL. Declining stroke and vascular event recurrence rates in secondary prevention trials over the past 50 years and consequences for current trial design. Circulation. 2011;123: 2111-2119.
39. Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Do all young ischemic stroke patients need long-term secondary preventive medication?. Neurology. 2005;65:609-611. (Pubitemid 41170726)
40. Ruiz-Irastorza G, Cuadrado MJ, Ruiz-Arruza I, Brey R, Crowther M, Derksen R, Erkan D, Krilis S, Machin S, Pengo V, Pierangeli S, Tektonidou M, Khamashta M. Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on Antiphospholipid Antibodies. Lupus. 2011;20:206-218.
41. de los Ríos F, Kleindorfer DO, Khoury J, Broderick JP, Moomaw CJ, Adeoye O, Flaherty ML, Khatri P, Woo D, Alwell K, Eilerman J, Ferioli S, Kissela BM. Trends in substance abuse preceding stroke among young adults: a population-based study. Stroke. 2012;43:3179-3183.