-
1
-
-
17144446761
-
A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membranespanning protein
-
CrossRef Medline
-
Arévalo JC, Yano H, Teng KK, Chao MV (2004) A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membranespanning protein. EMBO J 23:2358-2368. CrossRef Medline
-
(2004)
EMBO J
, vol.23
, pp. 2358-2368
-
-
Arévalo, J.C.1
Yano, H.2
Teng, K.K.3
Chao, M.V.4
-
2
-
-
33646396185
-
Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination
-
CrossRef Medline
-
Arévalo JC, Waite J, Rajagopal R, Beyna M, Chen ZY, Lee FS, Chao MV (2006) Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination. Neuron 50:549-559. CrossRef Medline
-
(2006)
Neuron
, vol.50
, pp. 549-559
-
-
Arévalo, J.C.1
Waite, J.2
Rajagopal, R.3
Beyna, M.4
Chen, Z.Y.5
Lee, F.S.6
Chao, M.V.7
-
3
-
-
65649100070
-
Synthesis, conformation, and biological characterization of a sugar derivative of morphine that is a potent, long-lasting, and nontolerant antinociceptive
-
CrossRef Medline
-
Arsequell G, Salvatella M, Valencia G, Fernández-Mayoralas A, Fontanella M, Venturi C, Jiménez-Barbero J, Marrón E, Rodríguez RE (2009) Synthesis, conformation, and biological characterization of a sugar derivative of morphine that is a potent, long-lasting, and nontolerant antinociceptive. J Med Chem 52:2656-2666. CrossRef Medline
-
(2009)
J Med Chem
, vol.52
, pp. 2656-2666
-
-
Arsequell, G.1
Salvatella, M.2
Valencia, G.3
Fernández-Mayoralas, A.4
Fontanella, M.5
Venturi, C.6
Jiménez-Barbero, J.7
Marrón, E.8
Rodríguez, R.E.9
-
4
-
-
0037762690
-
Neurotrophins and their receptors: A convergence point for many signalling pathways
-
CrossRef Medline
-
Chao MV (2003) Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat Rev Neurosci 4:299-309. CrossRef Medline
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 299-309
-
-
Chao, M.V.1
-
5
-
-
33845901486
-
An SCN9A channelopathy causes congenital inability to experience pain
-
CrossRef Medline
-
Cox JJ, Reimann F, Nicholas AK, Thornton G, Roberts E, Springell K, Karbani G, Jafri H, Mannan J, Raashid Y, Al-Gazali L, Hamamy H, Valente EM, Gorman S, Williams R, McHale DP, Wood JN, Gribble FM, Woods CG (2006) An SCN9A channelopathy causes congenital inability to experience pain. Nature 444:894-898. CrossRef Medline
-
(2006)
Nature
, vol.444
, pp. 894-898
-
-
Cox, J.J.1
Reimann, F.2
Nicholas, A.K.3
Thornton, G.4
Roberts, E.5
Springell, K.6
Karbani, G.7
Jafri, H.8
Mannan, J.9
Raashid, Y.10
Al-Gazali, L.11
Hamamy, H.12
Valente, E.M.13
Gorman, S.14
Williams, R.15
McHale, D.P.16
Wood, J.N.17
Gribble, F.M.18
Woods, C.G.19
-
6
-
-
0028297308
-
Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons
-
CrossRef Medline
-
Crowley C, Spencer SD, Nishimura MC, Chen KS, Pitts-Meek S, Armanini MP, Ling LH, McMahon SB, Shelton DL, Levinson AD (1994) Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76: 1001-1011. CrossRef Medline
-
(1994)
Cell
, vol.76
, pp. 1001-1011
-
-
Crowley, C.1
Spencer, S.D.2
Nishimura, M.C.3
Chen, K.S.4
Pitts-Meek, S.5
Armanini, M.P.6
Ling, L.H.7
McMahon, S.B.8
Shelton, D.L.9
Levinson, A.D.10
-
7
-
-
42349090693
-
A model for neuronal competition during development
-
CrossRef Medline
-
Deppmann CD, Mihalas S, Sharma N, Lonze BE, Niebur E, GintyDD (2008) A model for neuronal competition during development. Science 320: 369-373. CrossRef Medline
-
(2008)
Science
, vol.320
, pp. 369-373
-
-
Deppmann, C.D.1
Mihalas, S.2
Sharma, N.3
Lonze, B.E.4
Niebur, E.5
Ginty, D.D.6
-
8
-
-
33847168937
-
SCN9A mutations in paroxysmal extreme pain disorder: Allelic variants underlie distinct channel defects and phenotypes
-
CrossRef Medline
-
Fertleman CR, Baker MD, Parker KA, Moffatt S, Elmslie FV, Abrahamsen B, Ostman J, Klugbauer N, Wood JN, Gardiner RM, Rees M (2006) SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron 52:767-774. CrossRef Medline
-
(2006)
Neuron
, vol.52
, pp. 767-774
-
-
Fertleman, C.R.1
Baker, M.D.2
Parker, K.A.3
Moffatt, S.4
Elmslie, F.V.5
Abrahamsen, B.6
Ostman, J.7
Klugbauer, N.8
Wood, J.N.9
Gardiner, R.M.10
Rees, M.11
-
9
-
-
26944484011
-
Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling
-
CrossRef Medline
-
Geetha T, Jiang J, Wooten MW (2005) Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling. Mol Cell 20:301-312. CrossRef Medline
-
(2005)
Mol Cell
, vol.20
, pp. 301-312
-
-
Geetha, T.1
Jiang, J.2
Wooten, M.W.3
-
10
-
-
0022344633
-
Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells
-
Medline
-
Greenberg ME, Greene LA, Ziff EB (1985) Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. J Biol Chem 260:14101-14110. Medline
-
(1985)
J Biol Chem
, vol.260
, pp. 14101-14110
-
-
Greenberg, M.E.1
Greene, L.A.2
Ziff, E.B.3
-
11
-
-
79958216680
-
Local insulin and the rapid regrowth of diabetic epidermal axons
-
CrossRef Medline
-
Guo G, Kan M, Martinez JA, Zochodne DW (2011a) Local insulin and the rapid regrowth of diabetic epidermal axons. Neurobiol Dis 43:414-421. CrossRef Medline
-
(2011)
Neurobiol Dis
, vol.43
, pp. 414-421
-
-
Guo, G.1
Kan, M.2
Martinez, J.A.3
Zochodne, D.W.4
-
12
-
-
78650679999
-
An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates
-
CrossRef Medline
-
Guo T, Mandai K, Condie BG, Wickramasinghe SR, Capecchi MR, Ginty DD (2011b) An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. Nat Neurosci 14:31-36. CrossRef Medline
-
(2011)
Nat Neurosci
, vol.14
, pp. 31-36
-
-
Guo, T.1
Mandai, K.2
Condie, B.G.3
Wickramasinghe, S.R.4
Capecchi, M.R.5
Ginty, D.D.6
-
13
-
-
0025774207
-
High-affinity NGF binding requires coexpression of the trk protooncogene and the low-affinity NGF receptor
-
CrossRef Medline
-
Hempstead BL, Martin-Zanca D, Kaplan DR, Parada LF, Chao MV (1991) High-affinity NGF binding requires coexpression of the trk protooncogene and the low-affinity NGF receptor. Nature 350:678-683. CrossRef Medline
-
(1991)
Nature
, vol.350
, pp. 678-683
-
-
Hempstead, B.L.1
Martin-Zanca, D.2
Kaplan, D.R.3
Parada, L.F.4
Chao, M.V.5
-
14
-
-
0041488911
-
Trk receptors: Roles in neuronal signal transduction
-
CrossRef Medline
-
Huang EJ, Reichardt LF (2003) Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 72:609-642. CrossRef Medline
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichardt, L.F.2
-
15
-
-
0035205827
-
Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): Mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor
-
CrossRef Medline
-
Indo Y (2001) Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor. Hum Mutat 18:462-471. CrossRef Medline
-
(2001)
Hum Mutat
, vol.18
, pp. 462-471
-
-
Indo, Y.1
-
16
-
-
84866178842
-
Nerve growth factor and the physiology of pain: Lessons from congenital insensitivity to pain with anhidrosis
-
CrossRef Medline
-
Indo Y (2012) Nerve growth factor and the physiology of pain: lessons from congenital insensitivity to pain with anhidrosis. Clin Genet 82:341-350. CrossRef Medline
-
(2012)
Clin Genet
, vol.82
, pp. 341-350
-
-
Indo, Y.1
-
17
-
-
15844369925
-
Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis
-
CrossRef Medline
-
Indo Y, Tsuruta M, Hayashida Y, Karim MA, Ohta K, Kawano T, Mitsubuchi H, Tonoki H, Awaya Y, Matsuda I (1996) Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis. Nat Genet 13:485-488. CrossRef Medline
-
(1996)
Nat Genet
, vol.13
, pp. 485-488
-
-
Indo, Y.1
Tsuruta, M.2
Hayashida, Y.3
Karim, M.A.4
Ohta, K.5
Kawano, T.6
Mitsubuchi, H.7
Tonoki, H.8
Awaya, Y.9
Matsuda, I.10
-
18
-
-
84896755329
-
TrkA in vivo function is negatively regulated by ubiquitination
-
CrossRef Medline
-
Kiris E, Wang T, Yanpallewar S, Dorsey SG, Becker J, Bavari S, Palko ME, Coppola V, Tessarollo L (2014) TrkA in vivo function is negatively regulated by ubiquitination. J Neurosci 34:4090-4098. CrossRef Medline
-
(2014)
J Neurosci
, vol.34
, pp. 4090-4098
-
-
Kiris, E.1
Wang, T.2
Yanpallewar, S.3
Dorsey, S.G.4
Becker, J.5
Bavari, S.6
Palko, M.E.7
Coppola, V.8
Tessarollo, L.9
-
19
-
-
84879658348
-
Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain
-
CrossRef Medline
-
Laedermann CJ, Cachemaille M, Kirschmann G, Pertin M, Gosselin RD, Chang I, Albesa M, Towne C, Schneider BL, Kellenberger S, Abriel H, Decosterd I (2013) Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain. J Clin Invest 123:3002-3013. CrossRef Medline
-
(2013)
J Clin Invest
, vol.123
, pp. 3002-3013
-
-
Laedermann, C.J.1
Cachemaille, M.2
Kirschmann, G.3
Pertin, M.4
Gosselin, R.D.5
Chang, I.6
Albesa, M.7
Towne, C.8
Schneider, B.L.9
Kellenberger, S.10
Abriel, H.11
Decosterd, I.12
-
20
-
-
77957934893
-
Tanezumab for the treatment of pain from osteoarthritis of the knee
-
CrossRef Medline
-
Lane NE, Schnitzer TJ, Birbara CA, Mokhtarani M, Shelton DL, Smith MD, Brown MT (2010) Tanezumab for the treatment of pain from osteoarthritis of the knee. N Engl J Med 363:1521-1531. CrossRef Medline
-
(2010)
N Engl J Med
, vol.363
, pp. 1521-1531
-
-
Lane, N.E.1
Schnitzer, T.J.2
Birbara, C.A.3
Mokhtarani, M.4
Shelton, D.L.5
Smith, M.D.6
Brown, M.T.7
-
21
-
-
0027406813
-
Nerve growth factor-induced hyperalgesia in the neonatal and adult rat
-
Medline
-
Lewin GR, Ritter AM, Mendell LM (1993) Nerve growth factor-induced hyperalgesia in the neonatal and adult rat. J Neurosci 13:2136-2148. Medline
-
(1993)
J Neurosci
, vol.13
, pp. 2136-2148
-
-
Lewin, G.R.1
Ritter, A.M.2
Mendell, L.M.3
-
22
-
-
0024503489
-
Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons
-
CrossRef Medline
-
Lindsay RM, Harmar AJ (1989) Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons. Nature 337:362-364. CrossRef Medline
-
(1989)
Nature
, vol.337
, pp. 362-364
-
-
Lindsay, R.M.1
Harmar, A.J.2
-
23
-
-
27344449759
-
p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation
-
CrossRef Medline
-
Makkerh JP, Ceni C, Auld DS, Vaillancourt F, Dorval G, Barker PA (2005) p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation. EMBO Rep 6:936-941. CrossRef Medline
-
(2005)
EMBO Rep
, vol.6
, pp. 936-941
-
-
Makkerh, J.P.1
Ceni, C.2
Auld, D.S.3
Vaillancourt, F.4
Dorval, G.5
Barker, P.A.6
-
24
-
-
79959509581
-
Antagonism of nerve growth factor-TrkA signaling and the relief of pain
-
CrossRef Medline
-
Mantyh PW, Koltzenburg M, Mendell LM, Tive L, Shelton DL (2011) Antagonism of nerve growth factor-TrkA signaling and the relief of pain. Anesthesiology 115:189-204. CrossRef Medline
-
(2011)
Anesthesiology
, vol.115
, pp. 189-204
-
-
Mantyh, P.W.1
Koltzenburg, M.2
Mendell, L.M.3
Tive, L.4
Shelton, D.L.5
-
25
-
-
0022641294
-
A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences
-
CrossRef Medline
-
Martin-Zanca D, Hughes SH, Barbacid M (1986) A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences. Nature 319:743-748. CrossRef Medline
-
(1986)
Nature
, vol.319
, pp. 743-748
-
-
Martin-Zanca, D.1
Hughes, S.H.2
Barbacid, M.3
-
26
-
-
0025323817
-
Expression of the trk protooncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development
-
CrossRef Medline
-
Martin-Zanca D, Barbacid M, Parada LF (1990) Expression of the trk protooncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development. Genes Dev 4:683-694. CrossRef Medline
-
(1990)
Genes Dev
, vol.4
, pp. 683-694
-
-
Martin-Zanca, D.1
Barbacid, M.2
Parada, L.F.3
-
27
-
-
0030605484
-
NGFas a mediator of inflammatory pain
-
CrossRef Medline
-
McMahon SB (1996) NGFas a mediator of inflammatory pain. Philos Trans R Soc Lond B Biol Sci 351:431-440. CrossRef Medline
-
(1996)
Philos Trans R Soc Lond B Biol Sci
, vol.351
, pp. 431-440
-
-
McMahon, S.B.1
-
28
-
-
0029085192
-
The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule
-
CrossRef Medline
-
McMahon SB, Bennett DL, Priestley JV, Shelton DL (1995) The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule. Nat Med 1:774-780. CrossRef Medline
-
(1995)
Nat Med
, vol.1
, pp. 774-780
-
-
McMahon, S.B.1
Bennett, D.L.2
Priestley, J.V.3
Shelton, D.L.4
-
29
-
-
0019195743
-
Requirement of nerve growth factor for development of substance P-containing sensory neurones
-
CrossRef Medline
-
Otten U, Goedert M, Mayer N, Lembeck F (1980) Requirement of nerve growth factor for development of substance P-containing sensory neurones. Nature 287:158-159. CrossRef Medline
-
(1980)
Nature
, vol.287
, pp. 158-159
-
-
Otten, U.1
Goedert, M.2
Mayer, N.3
Lembeck, F.4
-
30
-
-
3342884404
-
Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes
-
CrossRef Medline
-
Rajagopal R, Chen ZY, Lee FS, Chao MV (2004) Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes. J Neurosci 24:6650-6658. CrossRef Medline
-
(2004)
J Neurosci
, vol.24
, pp. 6650-6658
-
-
Rajagopal, R.1
Chen, Z.Y.2
Lee, F.S.3
Chao, M.V.4
-
31
-
-
77950429077
-
Pain perception is altered by a nucleotide polymorphism in SCN9A
-
CrossRef Medline
-
Reimann F, Cox JJ, Belfer I, Diatchenko L, Zaykin DV, McHale DP, Drenth JP, Dai F, Wheeler J, Sanders F, Wood L, WuTX, Karppinen J, Nikolajsen L, Männikko M, Max MB, Kiselycznyk C, Poddar M, Te Morsche RH, Smith S, Gibson D, Kelempisioti A, Maixner W, Gribble FM, Woods CG (2010) Pain perception is altered by a nucleotide polymorphism in SCN9A. Proc Natl Acad Sci U S A 107:5148-5153. CrossRef Medline
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5148-5153
-
-
Reimann, F.1
Cox, J.J.2
Belfer, I.3
Diatchenko, L.4
Zaykin, D.V.5
McHale, D.P.6
Drenth, J.P.7
Dai, F.8
Wheeler, J.9
Sanders, F.10
Wood, L.11
Wu, T.X.12
Karppinen, J.13
Nikolajsen, L.14
Männikko, M.15
Max, M.B.16
Kiselycznyk, C.17
Poddar, M.18
Te Morsche, R.H.19
Smith, S.20
Gibson, D.21
Kelempisioti, A.22
Maixner, W.23
Gribble, F.M.24
Woods, C.G.25
more..
-
32
-
-
0028331599
-
Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene
-
CrossRef Medline
-
Smeyne RJ, Klein R, Schnapp A, Long LK, Bryant S, Lewin A, Lira SA, BarbacidM (1994) Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368:246-249. CrossRef Medline
-
(1994)
Nature
, vol.368
, pp. 246-249
-
-
Smeyne, R.J.1
Klein, R.2
Schnapp, A.3
Long, L.K.4
Bryant, S.5
Lewin, A.6
Lira, S.A.7
Barbacid, M.8
-
33
-
-
69249137477
-
Endocytosis and signalling: Intertwining molecular networks
-
CrossRef Medline
-
Sorkin A, von Zastrow M (2009) Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol 10:609-622. CrossRef Medline
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 609-622
-
-
Sorkin, A.1
von Zastrow, M.2
-
34
-
-
0027161953
-
trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues
-
Medline
-
Tessarollo L, Tsoulfas P, Martin-Zanca D, Gilbert DJ, Jenkins NA, Copeland NG, Parada LF (1993) trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues. Development 118:463-475. Medline
-
(1993)
Development
, vol.118
, pp. 463-475
-
-
Tessarollo, L.1
Tsoulfas, P.2
Martin-Zanca, D.3
Gilbert, D.J.4
Jenkins, N.A.5
Copeland, N.G.6
Parada, L.F.7
-
35
-
-
0028023450
-
Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity
-
CrossRef Medline
-
Woolf CJ, Safieh-Garabedian B, Ma QP, Crilly P, Winter J (1994) Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 62:327-331. CrossRef Medline
-
(1994)
Neuroscience
, vol.62
, pp. 327-331
-
-
Woolf, C.J.1
Safieh-Garabedian, B.2
Ma, Q.P.3
Crilly, P.4
Winter, J.5
-
36
-
-
77449124047
-
Nedd4 and Nedd4-2: Closely related ubiquitinprotein ligases with distinct physiological functions
-
CrossRef Medline
-
Yang B, Kumar S (2010) Nedd4 and Nedd4-2: closely related ubiquitinprotein ligases with distinct physiological functions. Cell Death Differ 17:68-77. CrossRef Medline
-
(2010)
Cell Death Differ
, vol.17
, pp. 68-77
-
-
Yang, B.1
Kumar, S.2
-
37
-
-
79952792911
-
Regulation of trafficking of activated TrkA is critical for NGF-mediated functions
-
CrossRef Medline
-
Yu T, Calvo L, Anta B, Ló pez-Benito S, Southon E, Chao MV, Tessarollo L, Arévalo JC (2011) Regulation of trafficking of activated TrkA is critical for NGF-mediated functions. Traffic 12:521-534. CrossRef Medline
-
(2011)
Traffic
, vol.12
, pp. 521-534
-
-
Yu, T.1
Calvo, L.2
Anta, B.3
Ló pez-Benito, S.4
Southon, E.5
Chao, M.V.6
Tessarollo, L.7
Arévalo, J.C.8
|