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Volumn 84, Issue 2, 2014, Pages 97-100

Molecular targeted therapy for early-stage non-small-cell lung cancer: Will it increase the cure rate?

Author keywords

Early stage; Locally advanced stage; Non small cell lung cancer; Targeted therapies

Indexed keywords

BEVACIZUMAB; CANCER VACCINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ETOPOSIDE; GEFITINIB; MELANOMA ANTIGEN 3; MONOCLONAL ANTIBODY; PACLITAXEL; PEMETREXED; PROTEIN TYROSINE KINASE INHIBITOR; TECEMOTIDE; ANGIOGENESIS INHIBITOR; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE INHIBITOR;

EID: 84899482991     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2014.01.018     Document Type: Editorial
Times cited : (20)

References (36)
  • 2
    • 34548457234 scopus 로고    scopus 로고
    • The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours
    • Epub 2007/09/01
    • Goldstraw P., Crowley J., Chansky K., Giroux D.J., Groome P.A., Rami-Porta R., et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2007, 2(8):706-714. Epub 2007/09/01.
    • (2007) J Thorac Oncol , vol.2 , Issue.8 , pp. 706-714
    • Goldstraw, P.1    Crowley, J.2    Chansky, K.3    Giroux, D.J.4    Groome, P.A.5    Rami-Porta, R.6
  • 3
    • 0032566225 scopus 로고    scopus 로고
    • Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomised controlled trials
    • Epub 1998/08/05, PORT Meta-analysis Trialists Group
    • PORT Meta-analysis Trialists Group Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomised controlled trials. Lancet 1998, 352(9124):257-263. Epub 1998/08/05.
    • (1998) Lancet , vol.352 , Issue.9124 , pp. 257-263
  • 4
    • 0346238665 scopus 로고    scopus 로고
    • Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
    • Epub 2004/01/23
    • Arriagada R., Bergman B., Dunant A., Le Chevalier T., Pignon J.P., Vansteenkiste J. Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med 2004, 350(4):351-360. Epub 2004/01/23.
    • (2004) N Engl J Med , vol.350 , Issue.4 , pp. 351-360
    • Arriagada, R.1    Bergman, B.2    Dunant, A.3    Le Chevalier, T.4    Pignon, J.P.5    Vansteenkiste, J.6
  • 5
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Epub 2006/12/15
    • Sandler A., Gray R., Perry M.C., Brahmer J., Schiller J.H., Dowlati A., et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006, 355(24):2542-2550. Epub 2006/12/15.
    • (2006) N Engl J Med , vol.355 , Issue.24 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3    Brahmer, J.4    Schiller, J.H.5    Dowlati, A.6
  • 6
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Epub 2009/08/21
    • Mok T.S., Wu Y.L., Thongprasert S., Yang C.H., Chu D.T., Saijo N., et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009, 361(10):947-957. Epub 2009/08/21.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3    Yang, C.H.4    Chu, D.T.5    Saijo, N.6
  • 7
    • 84879071011 scopus 로고    scopus 로고
    • Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
    • Epub 2013/06/04
    • Shaw A.T., Kim D.W., Nakagawa K., Seto T., Crino L., Ahn M.J., et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 2013, 368(25):2385-2394. Epub 2013/06/04.
    • (2013) N Engl J Med , vol.368 , Issue.25 , pp. 2385-2394
    • Shaw, A.T.1    Kim, D.W.2    Nakagawa, K.3    Seto, T.4    Crino, L.5    Ahn, M.J.6
  • 8
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • Epub 2010/06/25
    • Maemondo M., Inoue A., Kobayashi K., Sugawara S., Oizumi S., Isobe H., et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010, 362(25):2380-2388. Epub 2010/06/25.
    • (2010) N Engl J Med , vol.362 , Issue.25 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3    Sugawara, S.4    Oizumi, S.5    Isobe, H.6
  • 9
    • 79960889662 scopus 로고    scopus 로고
    • Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
    • Epub 2011/07/26
    • Zhou C., Wu Y.L., Chen G., Feng J., Liu X.Q., Wang C., et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011, 12(8):735-742. Epub 2011/07/26.
    • (2011) Lancet Oncol , vol.12 , Issue.8 , pp. 735-742
    • Zhou, C.1    Wu, Y.L.2    Chen, G.3    Feng, J.4    Liu, X.Q.5    Wang, C.6
  • 10
    • 84884736973 scopus 로고    scopus 로고
    • Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations
    • Epub 2013/07/03
    • Sequist L.V., Yang J.C., Yamamoto N., O'Byrne K., Hirsh V., Mok T., et al. Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations. J Clin Oncol 2013, 31(27):3327-3334. Epub 2013/07/03.
    • (2013) J Clin Oncol , vol.31 , Issue.27 , pp. 3327-3334
    • Sequist, L.V.1    Yang, J.C.2    Yamamoto, N.3    O'Byrne, K.4    Hirsh, V.5    Mok, T.6
  • 11
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
    • Epub 2012/01/31
    • Rosell R., Carcereny E., Gervais R., Vergnenegre A., Massuti B., Felip E., et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012, 13(3):239-246. Epub 2012/01/31.
    • (2012) Lancet Oncol , vol.13 , Issue.3 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3    Vergnenegre, A.4    Massuti, B.5    Felip, E.6
  • 13
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study
    • Epub 2010/05/25
    • Cappuzzo F., Ciuleanu T., Stelmakh L., Cicenas S., Szczesna A., Juhasz E., et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010, 11(6):521-529. Epub 2010/05/25.
    • (2010) Lancet Oncol , vol.11 , Issue.6 , pp. 521-529
    • Cappuzzo, F.1    Ciuleanu, T.2    Stelmakh, L.3    Cicenas, S.4    Szczesna, A.5    Juhasz, E.6
  • 14
    • 77956267159 scopus 로고    scopus 로고
    • Chemoradiotherapy and gefitinib in stage III non-small cell lung cancer with epidermal growth factor receptor and KRAS mutation analysis: cancer and leukemia group B (CALEB) 30106, a CALGB-stratified phase II trial
    • Ready N., Janne P.A., Bogart J., Dipetrillo T., Garst J., Graziano S., et al. Chemoradiotherapy and gefitinib in stage III non-small cell lung cancer with epidermal growth factor receptor and KRAS mutation analysis: cancer and leukemia group B (CALEB) 30106, a CALGB-stratified phase II trial. J Thorac Oncol 2010, 5(9):1382-1390.
    • (2010) J Thorac Oncol , vol.5 , Issue.9 , pp. 1382-1390
    • Ready, N.1    Janne, P.A.2    Bogart, J.3    Dipetrillo, T.4    Garst, J.5    Graziano, S.6
  • 15
    • 45149102984 scopus 로고    scopus 로고
    • Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023
    • Kelly K., Chansky K., Gaspar L.E., Albain K.S., Jett J., Ung Y.C., et al. Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023. J Clin Oncol 2008, 26(15):2450-2456.
    • (2008) J Clin Oncol , vol.26 , Issue.15 , pp. 2450-2456
    • Kelly, K.1    Chansky, K.2    Gaspar, L.E.3    Albain, K.S.4    Jett, J.5    Ung, Y.C.6
  • 16
    • 84861626518 scopus 로고    scopus 로고
    • Efficacy of maintenance erlotinib versus placebo in patients with unresectable stage III non-small cell lung cancer (NSCLC) following concurrent chemoradiation
    • Rigas J.R., Carey M.A., Rubin M.S., Dragnev K.H., Aitken C.L., Ghazal H., et al. Efficacy of maintenance erlotinib versus placebo in patients with unresectable stage III non-small cell lung cancer (NSCLC) following concurrent chemoradiation. J Thorac Oncol 2009, 4:s371.
    • (2009) J Thorac Oncol , vol.4
    • Rigas, J.R.1    Carey, M.A.2    Rubin, M.S.3    Dragnev, K.H.4    Aitken, C.L.5    Ghazal, H.6
  • 17
    • 79951773393 scopus 로고    scopus 로고
    • Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations
    • Epub 2010/12/15
    • Janjigian Y.Y., Park B.J., Zakowski M.F., Ladanyi M., Pao W., D'Angelo S.P., et al. Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations. J Thorac Oncol 2011, 6(3):569-575. Epub 2010/12/15.
    • (2011) J Thorac Oncol , vol.6 , Issue.3 , pp. 569-575
    • Janjigian, Y.Y.1    Park, B.J.2    Zakowski, M.F.3    Ladanyi, M.4    Pao, W.5    D'Angelo, S.P.6
  • 18
    • 84890896341 scopus 로고    scopus 로고
    • Gefitinib Versus Placebo in Completely Resected Non-Small-Cell Lung Cancer: Results of the NCIC CTG BR19 Study
    • Epub 2013/08/28
    • Goss G.D., O'Callaghan C., Lorimer I., Tsao M.S., Masters G.A., Jett J., et al. Gefitinib Versus Placebo in Completely Resected Non-Small-Cell Lung Cancer: Results of the NCIC CTG BR19 Study. J Clin Oncol 2013, 31(27):3320-3326. Epub 2013/08/28.
    • (2013) J Clin Oncol , vol.31 , Issue.27 , pp. 3320-3326
    • Goss, G.D.1    O'Callaghan, C.2    Lorimer, I.3    Tsao, M.S.4    Masters, G.A.5    Jett, J.6
  • 19
    • 84888792852 scopus 로고    scopus 로고
    • Results of the prospective, randomized, and customized NSCLC adjuvant phase II trial (IFCT-0801, TASTE trial) from the French Collaborative Intergroup
    • ASCO Meeting Abstracts
    • Soria J.-C., Barlesi F., Besse B., Mazieres J., Merle P., Cadranel J., et al. Results of the prospective, randomized, and customized NSCLC adjuvant phase II trial (IFCT-0801, TASTE trial) from the French Collaborative Intergroup. J Clin Oncol 2013, 31(Suppl. 15):7505. ASCO Meeting Abstracts.
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL. 15 , pp. 7505
    • Soria, J.-C.1    Barlesi, F.2    Besse, B.3    Mazieres, J.4    Merle, P.5    Cadranel, J.6
  • 20
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
    • Epub 2009/05/05
    • Pirker R., Pereira J.R., Szczesna A., von Pawel J., Krzakowski M., Ramlau R., et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet 2009, 373(9674):1525-1531. Epub 2009/05/05.
    • (2009) Lancet , vol.373 , Issue.9674 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3    von Pawel, J.4    Krzakowski, M.5    Ramlau, R.6
  • 21
    • 80051742422 scopus 로고    scopus 로고
    • Randomized phase II study of pemetrexed, carboplatin, and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small-cell lung cancer: cancer and leukemia group B trial 30407
    • Epub 2011/07/13
    • Govindan R., Bogart J., Stinchcombe T., Wang X., Hodgson L., Kratzke R., et al. Randomized phase II study of pemetrexed, carboplatin, and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small-cell lung cancer: cancer and leukemia group B trial 30407. J Clin Oncol 2011, 29(23):3120-3125. Epub 2011/07/13.
    • (2011) J Clin Oncol , vol.29 , Issue.23 , pp. 3120-3125
    • Govindan, R.1    Bogart, J.2    Stinchcombe, T.3    Wang, X.4    Hodgson, L.5    Kratzke, R.6
  • 22
    • 79959195283 scopus 로고    scopus 로고
    • Phase II study of cetuximab in combination with chemoradiation in patients with stage IIIA/B non-small-cell lung cancer: RTOG 0324
    • Epub 2011/05/11
    • Blumenschein G.R., Paulus R., Curran W.J., Robert F., Fossella F., Werner-Wasik M., et al. Phase II study of cetuximab in combination with chemoradiation in patients with stage IIIA/B non-small-cell lung cancer: RTOG 0324. J Clin Oncol 2011, 29(17):2312-2318. Epub 2011/05/11.
    • (2011) J Clin Oncol , vol.29 , Issue.17 , pp. 2312-2318
    • Blumenschein, G.R.1    Paulus, R.2    Curran, W.J.3    Robert, F.4    Fossella, F.5    Werner-Wasik, M.6
  • 23
    • 84886366457 scopus 로고    scopus 로고
    • A randomized phase III comparison of standard-dose (60Gy) versus high-dose (74Gy) conformal chemoradiotherapy with or without cetuximab for stage III non-small cell lung cancer: Results on radiation dose in RTOG 0617
    • ASCO Meeting Abstracts
    • Bradley J.D., Paulus R., Komaki R., Masters G.A., Forster K., Schild S.E., et al. A randomized phase III comparison of standard-dose (60Gy) versus high-dose (74Gy) conformal chemoradiotherapy with or without cetuximab for stage III non-small cell lung cancer: Results on radiation dose in RTOG 0617. J Clin Oncol 2013, 31(Suppl 15):7501. ASCO Meeting Abstracts.
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL 15 , pp. 7501
    • Bradley, J.D.1    Paulus, R.2    Komaki, R.3    Masters, G.A.4    Forster, K.5    Schild, S.E.6
  • 24
    • 84892876295 scopus 로고    scopus 로고
    • An Intergroup randomized phase III comparison of standard-dose (60Gy) versus high-dose (74Gy) chemorradiotherapy +/- cetuximab for stage III Non-Small Cell Lung Cancer: results from RTOG 0617
    • Jeffrey Bradley, Gregory Masters, Chen Hu, George Blumenschein, Jeff Bogart, Steve Schild, et al. An Intergroup randomized phase III comparison of standard-dose (60Gy) versus high-dose (74Gy) chemorradiotherapy +/- cetuximab for stage III Non-Small Cell Lung Cancer: results from RTOG 0617. Journal of Thoracic Oncology. 2013, S3.
    • (2013) Journal of Thoracic Oncology.
    • Bradley, J.1    Masters, G.2    Hu, C.3    Blumenschein, G.4    Bogart, J.5    Schild, S.6
  • 25
    • 77951473661 scopus 로고    scopus 로고
    • Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL)
    • Epub 2010/02/13
    • Reck M., von Pawel J., Zatloukal P., Ramlau R., Gorbounova V., Hirsh V., et al. Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL). Ann Oncol 2010, 21(9):1804-1809. Epub 2010/02/13.
    • (2010) Ann Oncol , vol.21 , Issue.9 , pp. 1804-1809
    • Reck, M.1    von Pawel, J.2    Zatloukal, P.3    Ramlau, R.4    Gorbounova, V.5    Hirsh, V.6
  • 26
    • 73949149605 scopus 로고    scopus 로고
    • Tracheoesophageal fistula formation in patients with lung cancer treated with chemoradiation and bevacizumab
    • Epub 2009/11/11
    • Spigel D.R., Hainsworth J.D., Yardley D.A., Raefsky E., Patton J., Peacock N., et al. Tracheoesophageal fistula formation in patients with lung cancer treated with chemoradiation and bevacizumab. J Clin Oncol 2010, 28(1):43-48. Epub 2009/11/11.
    • (2010) J Clin Oncol , vol.28 , Issue.1 , pp. 43-48
    • Spigel, D.R.1    Hainsworth, J.D.2    Yardley, D.A.3    Raefsky, E.4    Patton, J.5    Peacock, N.6
  • 27
    • 84869430260 scopus 로고    scopus 로고
    • Incorporating bevacizumab and erlotinib in the combined-modality treatment of stage III non-small-cell lung cancer: results of a phase I/II trial
    • Epub 2012/10/10.
    • Socinski M.A., Stinchcombe T.E., Moore D.T., Gettinger S.N., Decker R.H., Petty W.J., et al. Incorporating bevacizumab and erlotinib in the combined-modality treatment of stage III non-small-cell lung cancer: results of a phase I/II trial. J Clin Oncol 2012, 30(32):3953-3959. Epub 2012/10/10.
    • (2012) J Clin Oncol , vol.30 , Issue.32 , pp. 3953-3959
    • Socinski, M.A.1    Stinchcombe, T.E.2    Moore, D.T.3    Gettinger, S.N.4    Decker, R.H.5    Petty, W.J.6
  • 28
    • 84899479404 scopus 로고    scopus 로고
    • http://clinicaltrials.gov/ct2/show/NCT00334815?term=S0533&rank=1.
  • 30
    • 0037215111 scopus 로고    scopus 로고
    • Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report
    • Epub 2002/12/31
    • Marchand M., Punt C.J., Aamdal S., Escudier B., Kruit W.H., Keilholz U., et al. Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report. Eur J Cancer 2003, 39(1):70-77. Epub 2002/12/31.
    • (2003) Eur J Cancer , vol.39 , Issue.1 , pp. 70-77
    • Marchand, M.1    Punt, C.J.2    Aamdal, S.3    Escudier, B.4    Kruit, W.H.5    Keilholz, U.6
  • 31
    • 84880755387 scopus 로고    scopus 로고
    • Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results
    • Epub 2013/05/30
    • Vansteenkiste J., Zielinski M., Linder A., Dahabreh J., Gonzalez E.E., Malinowski W., et al. Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. J Clin Oncol 2013, 31(19):2396-2403. Epub 2013/05/30.
    • (2013) J Clin Oncol , vol.31 , Issue.19 , pp. 2396-2403
    • Vansteenkiste, J.1    Zielinski, M.2    Linder, A.3    Dahabreh, J.4    Gonzalez, E.E.5    Malinowski, W.6
  • 34
    • 1142286444 scopus 로고    scopus 로고
    • MUC1 immunobiology: from discovery to clinical applications
    • Epub 2004/02/21
    • Vlad A.M., Kettel J.C., Alajez N.M., Carlos C.A., Finn O.J. MUC1 immunobiology: from discovery to clinical applications. Adv Immunol 2004, 82:249-293. Epub 2004/02/21.
    • (2004) Adv Immunol , vol.82 , pp. 249-293
    • Vlad, A.M.1    Kettel, J.C.2    Alajez, N.M.3    Carlos, C.A.4    Finn, O.J.5
  • 35
    • 27244449289 scopus 로고    scopus 로고
    • Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer
    • Epub 2005/09/20
    • Butts C., Murray N., Maksymiuk A., Goss G., Marshall E., Soulieres D., et al. Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol 2005, 23(27):6674-6681. Epub 2005/09/20.
    • (2005) J Clin Oncol , vol.23 , Issue.27 , pp. 6674-6681
    • Butts, C.1    Murray, N.2    Maksymiuk, A.3    Goss, G.4    Marshall, E.5    Soulieres, D.6
  • 36
    • 84891373760 scopus 로고    scopus 로고
    • Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial
    • Epub 2013/12/18
    • Butts C., Socinski M.A., Mitchell P.L., Thatcher N., Havel L., Krzakowski M., et al. Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial. Lancet Oncol 2013, Epub 2013/12/18.
    • (2013) Lancet Oncol
    • Butts, C.1    Socinski, M.A.2    Mitchell, P.L.3    Thatcher, N.4    Havel, L.5    Krzakowski, M.6


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