Race and breast cancer survival by intrinsic subtype based on PAM50 gene expression

Breast Cancer Research and Treatment

Volumn 144, Issue 3, 2014, Pages 689-699

  Kroenke, Candyce H ^a   Sweeney, Carol ^b   Kwan, Marilyn L ^a   Quesenberry, Charles P ^a   Weltzien, Erin K ^a   Habel, Laurel A ^a   Castillo, Adrienne ^a   Bernard, Phillip S ^b   Factor, Rachel E ^b   Kushi, Lawrence H ^a   Caan, Bette J ^a  

^a DIVISION OF RESEARCH   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Breast cancer mortality; Breast cancer survival; Ethnicity; Gene expression; Intrinsic subtype; Molecular subtype; PAM50; Race

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TRASTUZUMAB;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BODY MASS; BREAST CANCER; CANCER CLASSIFICATION; CANCER MORTALITY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; COHORT ANALYSIS; CORRELATION ANALYSIS; EDUCATIONAL STATUS; ETHNIC DIFFERENCE; ETHNICITY; FEMALE; GENE EXPRESSION; GENE EXPRESSION ASSAY; GENETIC VARIABILITY; HEALTH DISPARITY; HUMAN; HUMAN TISSUE; ONCOGENE; PAM50 GENE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RACE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BREAST NEOPLASMS; CALIFORNIA; CASE-CONTROL STUDIES; ETHNIC GROUPS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MIDDLE AGED; RECURRENCE; REGISTRIES; RISK FACTORS; UTAH;

EID: 84899481560     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-2899-5     Document Type: Article

References (50)

1. Tannenbaum SL, Koru-Sengul T, Miao F, Byrne MM (2013) Disparities in survival after female breast cancer diagnosis: a population-based study. Cancer Causes Control 24(9):1705-1715
2. Sail K, Franzini L, Lairson D, Du X (2012) Differences in treatment and survival among African-American and Caucasian women with early stage operable breast cancer. Ethn Health 17(3):309-323
3. American Cancer Society (2009) Cancer facts and figures - 2009. American Cancer Society, Atlanta
4. Chlebowski RT, Chen Z, Anderson GL, Rohan T, Aragaki A, Lane D, Dolan NC, Paskett ED, McTiernan A, Hubbell FA et al (2005) Ethnicity and breast cancer: factors influencing differences in incidence and outcome. J Natl Cancer Inst 97(6):439-448
5. Deshpande AD, Jeffe DB, Gnerlich J, Iqbal AZ, Thummalakunta A, Margenthaler JA (2009) Racial disparities in breast cancer survival: an analysis by age and stage. J Surg Res 153(1):105-113
6. McBride R, Hershman D, Tsai WY, Jacobson JS, Grann V, Neugut AI (2007) Within-stage racial differences in tumor size and number of positive lymph nodes in women with breast cancer. Cancer 110(6):1201-1208 (Pubitemid 47435589)
7. Tammemagi CM, Nerenz D, Neslund-Dudas C, Feldkamp C, Nathanson D (2005) Comorbidity and survival disparities among black and white patients with breast cancer. JAMA 294(14):1765-1772 (Pubitemid 41434622)
8. Parise CA, Caggiano V (2013) Disparities in race/ethnicity and socioeconomic status: risk of mortality of breast cancer patients in the California Cancer Registry, 2000-2010. BMC Cancer 13(1):449
9. Pinheiro PS, Williams M, Miller EA, Easterday S, Moonie S, Trapido EJ (2011) Cancer survival among Latinos and the Hispanic Paradox. Cancer Causes Control 22(4):553-561
10. Silber JH, Rosenbaum PR, Clark AS, Giantonio BJ, Ross RN, Teng Y, Wang M, Niknam BA, Ludwig JA, Wang W et al (2013) Characteristics associated with differences in survival among black and white women with breast cancer. JAMA 310:389-397
11. Chatterjee NA, He Y, Keating NL (2013) Racial differences in breast cancer stage at diagnosis in the mammography era. Am J Public Health 103(1):170-176
12. Simon MS, Lamerato L, Krajenta R, Booza JC, Ruterbusch JJ, Kunz S, Schwartz K (2012) Racial differences in the use of adjuvant chemotherapy for breast cancer in a large urban integrated health system. Int J Breast Cancer 2012:453985
13. Dehal A, Abbas A, Johna S (2013) Racial disparities in clinical presentation, surgical treatment and in-hospital outcomes of women with breast cancer: analysis of nationwide inpatient sample database. Breast Cancer Res Treat 139(2):561-569
14. Smith EC, Ziogas A, Anton-Culver H (2013) Delay in surgical treatment and survival after breast cancer diagnosis in young women by race/ethnicity. JAMA Surg 148(6):516-523
15. Nurgalieva ZZ, Franzini L, Morgan RO, Vernon SW, Liu CC, Du XL (2013) Impact of timing of adjuvant chemotherapy initiation and completion after surgery on racial disparities in survival among women with breast cancer. Med Oncol 30(1):419
16. Balasubramanian BA, Demissie K, Crabtree BF, Strickland PA, Pawlish K, Rhoads GG (2012) Black Medicaid beneficiaries experience breast cancer treatment delays more frequently than whites. Ethn Dis 22(3):288-294
17. Du XL, Fang S, Meyer TE (2008) Impact of treatment and socioeconomic status on racial disparities in survival among older women with breast cancer. Am J Clin Oncol 31(2):125-132 (Pubitemid 351519163)
18. Akinyemiju TF, Soliman AS, Johnson NJ, Altekruse SF, Welch K, Banerjee M, Schwartz K, Merajver S (2013) Individual and neighborhood socioeconomic status and healthcare resources in relation to black-white breast cancer survival disparities. J Cancer Epidemiol 2013:490472
19. Dignam JJ (2001) Efficacy of systemic adjuvant therapy for breast cancer in African-American and Caucasian women. J Natl Cancer Inst Monogr 30:36-43
20. Albain KS, Unger JM, Crowley JJ, Coltman CA Jr (2009) Hershman DL: racial disparities in cancer survival among randomized clinical trials patients of the Southwest Oncology Group. J Natl Cancer Inst 101(14):984-992
21. Perou C (2013) PL01-03: the therapeutic implications of genome sequencing and expression analyses for breast cancer. In: American Association of Cancer Research (AACR), Washington
22. Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K, Karaca G, Troester MA, Tse CK, Edmiston S et al (2006) Race, breast cancer subtypes, and survival in the Carolina breast cancer study. JAMA 295(21):2492-2502 (Pubitemid 43854964)
23. O'Brien KM, Cole SR, Tse CK, Perou CM, Carey LA, Foulkes WD, Dressler LG, Geradts J, Millikan RC (2010) Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina breast cancer study. Clin Cancer Res 16(24):6100-6110
24. Ma H, Lu Y, Malone KE, Marchbanks PA, Deapen DM, Spirtas R, Burkman RT, Strom BL, McDonald JA, Folger SG et al (2013) Mortality risk of black women and white women with invasive breast cancer by hormone receptors, HER2, and p53 status. BMC Cancer 13:225
25. Haque R, Ahmed S, Schottinger J, Kwan M, Shi J, Chung J, Inzhakova G, Avila C, Kleinman K, Fletcher S (2012) PS1-05: disparities in breast cancer survival by molecular subtype and race/ethnicity; HMORN 2012 conference. Clin Med Res 10(3):145
26. Perez CA, Zumsteg ZS, Gupta G, Morrow M, Arnold B, Patil SM, Traina TA, Robson ME, Wen YH, McCormick B et al (2013) Black race as a prognostic factor in triple-negative breast cancer patients treated with breast-conserving therapy: a large, single-institution retrospective analysis. Breast Cancer Res Treat 139(2):497-506
27. Pacheco JM, Gao F, Bumb C, Ellis MJ, Ma CX (2013) Racial differences in outcomes of triple-negative breast cancer. Breast Cancer Res Treat 138(1):281-289
28. Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA et al (2000) Molecular portraits of human breast tumours. Nature 406(6797):747-752
29. Bastien RR, Rodriguez-Lescure A, Ebbert MT, Prat A, Munarriz B, Rowe L, Miller P, Ruiz-Borrego M, Anderson D, Lyons B et al (2012) PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers. BMC Med Genomics 5:44
30. Caan B, Sternfeld B, Gunderson E, Coates A, Quesenberry C, Slattery ML (2005) Life after cancer epidemiology (LACE) study: a cohort of early stage breast cancer survivors (United States). Cancer Causes Control 16(5):545-556 (Pubitemid 40933624)
31. Kwan ML, Ambrosone CB, Lee MM, Barlow J, Krathwohl SE, Ergas IJ, Ashley CH, Bittner JR, Darbinian J, Stronach K et al (2008) The pathways study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California. Cancer Causes Control 19(10):1065-1076
32. Borgan O, Langholz B, Samuelsen SO, Goldstein L, Pogoda J (2000) Exposure stratified case-cohort designs. Lifetime Data Anal 6(1):39-58
33. Prentice RL (1986) A case-cohort design for epidemiological cohort studies and disease prevention trials. Biometrika 73:1-11
34. Self SG, Prentice RL (1988) Asymptotic distribution theory and efficiency results for case-cohort studies. Ann Stat 16:64-81
35. Sweeney C, Bernard P, Factor RE, Kwan M, Habel LA, Quesenberry CP Jr, Shakespear K, Weltzien E, Stijleman IJ, Davis C et al (2014) Intrinsic subtypes from PAM50 gene expression assay in a population-based breast cancer cohort: differences by age, race, and tumor characteristics. Cancer Epidemiol Biomark Prev. doi:10.1158/1055-9965.EPI-13-1023
36. Parker JS, Mullins M, Cheang MC, Leung S, Voduc D, Vickery T, Davies S, Fauron C, He X, Hu Z et al (2009) Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 27(8):1160-1167
37. Ebbert MT, Bastien RR, Boucher KM, Martin M, Carrasco E, Caballero R, Stijleman IJ, Bernard PS, Facelli JC (2011) Characterization of uncertainty in the classification of multivariate assays: application to PAM50 centroid-based genomic predictors for breast cancer treatment plans. J Clin Bioinform 1:37
38. Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373-383 (Pubitemid 17055592)
39. Langholz B, Jiao J (2007) Computational methods for case-cohort studies. Comput Stat Data Anal 51:3737-3748 (Pubitemid 46509540)
40. Komenaka IK, Martinez ME, Pennington RE Jr, Hsu CH, Clare SE, Thompson PA, Murphy C, Zork NM, Goulet RJ Jr (2010) Race and ethnicity and breast cancer outcomes in an underinsured population. J Natl Cancer Inst 102(15):1178-1187
41. Yood MU, Johnson CC, Blount A, Abrams J, Wolman E, McCarthy BD, Raju U, Nathanson DS, Worsham M, Wolman SR (1999) Race and differences in breast cancer survival in a managed care population. J Natl Cancer Inst 91(17):1487-1491 (Pubitemid 29424554)
42. Sweeney C, Bernard PS, Factor RE, Kwan ML, Habel LA, Quesenberry CP, Shakespear K, Weltzien EK, Stijleman IJ, Davis CA et al (2013) Application of the PAM50 RT-qPCR-based intrinsic subtype classifier in a population-based breast cancer cohort: subtype associations with age, race, and tumor characteristics (in press)
43. Bauer KR, Brown M, Cress RD, Parise CA, Caggiano V (2007) Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer Registry. Cancer 109(9):1721-1728 (Pubitemid 46668532)
44. Caan BJ, Sweeney C, Habel LA, Kwan M, Kroenke CH, Weltzien E et al (2013) Intrinsic subtypes from the PAM50 gene expression assay in a population-based breast cancer survivor cohort: prognostication of short and long term outcomes. Cancer Epidemiol Biomark Prev. doi:10.1158/1055-9965.EPI-13-1017
45. Maskarinec G, Sen C, Koga K, Conroy SM (2011) Ethnic differences in breast cancer survival: status and determinants. Womens Health (Lond Engl) 7(6):677-687
46. Bosco JL, Lash TL, Prout MN, Buist DS, Geiger AM, Haque R, Wei F, Silliman RA (2009) Breast cancer recurrence in older women five to ten years after diagnosis. Cancer Epidemiol Biomark Prev 18(11):2979-2983
47. Elledge RM, Clark GM, Chamness GC, Osborne CK (1994) Tumor biologic factors and breast cancer prognosis among white, Hispanic, and black women in the United States. J Natl Cancer Inst 86(9):705-712 (Pubitemid 24138977)
48. Philips BU Jr, Belasco E, Markides KS, Gong G (2013) Socioeconomic deprivation as a determinant of cancer mortality and the Hispanic paradox in Texas, USA. Int J Equity Health 12:26
49. Palloni A, Morenoff JD (2001) Interpreting the paradoxical in the hispanic paradox: demographic and epidemiologic approaches. Ann NY Acad Sci 954:140-174 (Pubitemid 34048920)
50. Hershman D, McBride R, Jacobson JS, Lamerato L, Roberts K, Grann VR, Neugut AI (2005) Racial disparities in treatment and survival among women with early-stage breast cancer. J Clin Oncol 23(27):6639-6646 (Pubitemid 46190258)