Obesity associated inflammation in African American adolescents and adults

American Journal of the Medical Sciences

Volumn 347, Issue 5, 2014, Pages 357-363

  Deloach, Stephanie ^a   Keith, Scott W ^a   Gidding, Samuel S ^b   Falkner, Bonita ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

Author keywords

Adolescents; African Americans; CRP; Inflammation; Obesity

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLASMINOGEN ACTIVATOR INHIBITOR 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

ADOLESCENT; ADULT; AFRICAN AMERICAN; AGE; ANTHROPOMETRY; ARTICLE; BLOOD PRESSURE; BODY MASS; CHILDHOOD OBESITY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GLUCOSE TOLERANCE; HUMAN; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; OBESITY; OBSERVATIONAL STUDY; PREVALENCE; PROTEIN BLOOD LEVEL; SMOKING; WAIST CIRCUMFERENCE; YOUNG ADULT;

ADOLESCENT; ADULT; AFRICAN AMERICANS; BLOOD PRESSURE; BODY MASS INDEX; C-REACTIVE PROTEIN; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; OBESITY; RISK FACTORS; YOUNG ADULT;

EID: 84899472636     PISSN: 00029629     EISSN: 15382990     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e31829555f0     Document Type: Article

References (30)

1. Libby P, Ridker PM, Hansson GK. Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol 2009;54:2129-38.
2. Devaraj S, Singh U, Jialal I. The evolving role of C-reactive protein in atherothrombosis. Clin Chem 2009;55:229-38.
3. Yudkin JS, Stehouwer CD, Emeis JJ, et al. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 1999;19:972-8.
4. Kistorp C, Raymond I, Pedersen F, et al. N-terminal pro-brain natriuretic peptide, C-reactive protein, and urinary albumin levels as predictors of mortality and cardiovascular events in older adults. JAMA 2005; 293:1609-16.
5. Ford ES. C-reactive protein concentration and cardiovascular disease risk factors in children: findings from the National Health and Nutrition Examination Survey 1999-2000. Circulation 2003;108:1053-8.
6. Moran A, Steffen LM, Jacobs DR Jr, et al. Relation of C-reactive protein to insulin resistance and cardiovascular risk factors in youth. Diabetes Care 2005;28:1763-8.
7. Cook DG, Mendall MA, Whincup PH, et al. C-reactive protein concentration in children: relationship to adiposity and other cardiovascular risk factors. Atherosclerosis 2000;149:139-50.
8. Juonala M, Viikari JS, Ronnemaa T, et al. Childhood C-reactive protein in predicting CRP and carotid intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. Arterioscler Thromb Vasc Biol 2006;26:1883-8.
9. Zieske AW, Tracy RP, McMahan CA, et al. Elevated serum C-reactive protein levels and advanced atherosclerosis in youth. Arterioscler Thromb Vasc Biol 2005;25:1237-43.
10. Huan YDS, Keith SW, Pequignot EC, et al. High blood pressure and obesity increase the risk of abnormal glucose tolerance in young adult African Americans. J Clin Hypertens (Greenwich) 2011;13:397-403.
11. DeLoach SHY, Keith SW, Martinez Cantarin MP, et al. Relationship of blood pressure and obesity with inflammatory cytokines among African Americans. Ther Adv Cardiovasc Dis 2011;5:149-57.
12. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-9.
13. Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22:1462-70.
14. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 2001;285:2486-97.
15. Cook S, Weitzman M, Auinger P, et al. Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Arch Pediatr Adolesc Med 2003;157:821-7.
16. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc 1995;57:289-300.
17. Efron BHT, Johnstone I, Tibshirani R. Least angle regression (with discussion). Ann Stat 2004;32:407-99.
18. Fox ER, Benjamin EJ, Sarpong DF, et al. Epidemiology, heritability, and genetic linkage of C-reactive protein in African Americans (from the Jackson Heart Study). Am J Cardiol 2008;102:835-41.
19. Rasouli N, Kern PA. Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab 2008;93:S64-73.
20. Kern PA, Di Gregorio GB, Lu T, et al. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 2003;52:1779-85.
21. Palaniappan L, Carnethon MR, Wang Y, et al. Predictors of the incident metabolic syndrome in adults: the Insulin Resistance Atherosclerosis Study. Diabetes Care 2004;27:788-93.
22. Musso C, Graffigna M, Soutelo J, et al. Cardiometabolic risk factors as apolipoprotein B, triglyceride/HDL-cholesterol ratio and C-reactive protein, in adolescents with and without obesity: cross-sectional study in middle class suburban children. Pediatr Diabetes 2011;12:229-34.
23. Vikram NK, Misra A, Dwivedi M, et al. Correlations of C-reactive protein levels with anthropometric profile, percentage of body fat and lipids in healthy adolescents and young adults in urban North India. Atherosclerosis 2003;168:305-13.
24. Sinaiko AR, Steinberger J,Moran A, et al. Relation of body mass index and insulin resistance to cardiovascular risk factors, inflammatory factors, and oxidative stress during adolescence. Circulation 2005;111:1985-91.
25. Juonala M, Juhola J, Magnussen CG, et al. Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study. J Clin Endocrinol Metab 2011;96:E15429.
26. Rebelo F, Schlussel MM, Vaz JS, et al. C-reactive protein and later preeclampsia: systemic review and meta-analysis taking into account the weight status. J Hypertens 2013;31:16-26.
27. Amiel SA, Sherwin RS, Simonson DC, et al. Impaired insulin action in puberty. A contributing factor to poor glycemic control in adolescents with diabetes. N Engl J Med 1986;315:215-9.
28. Caprio S, Plewe G, Diamond MP, et al. Increased insulin secretion in puberty: a compensatory response to reductions in insulin sensitivity. J Pediatr 1989;114:963-7.
29. Moran A, Jacobs DR Jr, Steinberger J, et al. Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 1999;48:2039-44.
30. Ogden CL, Carroll MD, Kit BK, et al. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012;307:483-90.