Tuberculosis in healthcare workers - A narrative review from a German perspective

Journal of Occupational Medicine and Toxicology

Volumn 9, Issue 1, 2014, Pages

  Nienhaus, Albert ^a,b   Schablon, Anja ^a   Preisser, Alexandra M ^a   Ringshausen, Felix C ^c   Diel, Roland ^d,e  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b Health and Welfare Services   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^e Member of the German Center for Lung Research   (Germany)

Author keywords

Assessment; Healthcare; Occupational disease; Prevention; Provision; Tuberculosis

Indexed keywords

DISINFECTANT AGENT; ISONIAZID; RIFAMPICIN; TUBERCULOSTATIC AGENT;

AIR CONDITIONING; ANAMNESIS; BREATHING; BRONCHOSCOPY; CHEMOPROPHYLAXIS; CONTACT EXAMINATION; DISEASE COURSE; DISEASE DURATION; DISINFECTION; GERIATRIC CARE; GERIATRIC NURSING; GERIATRICS; GERMANY; HEALTH CARE COST; HEALTH CARE PERSONNEL; HEALTH INSURANCE; HUMAN; INCIDENCE; INCOME; INFECTION PREVENTION; INFECTION RISK; INSTRUMENT STERILIZATION; INTERFERON GAMMA RELEASE ASSAY; LATENT TUBERCULOSIS; LIVER TOXICITY; LUNG TUBERCULOSIS; MEDICATION COMPLIANCE; META ANALYSIS (TOPIC); NARRATIVE; OCCUPATIONAL DISEASE; OCCUPATIONAL SAFETY; PATIENT COMPLIANCE; POSTPRIMARY TUBERCULOSIS; PREVALENCE; PRIMARY TUBERCULOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATORY TRACT INTUBATION; REVIEW; RISK ASSESSMENT; RISK FACTOR; SOCIAL HYGIENE; TUBERCULIN TEST; TUBERCULOSIS; TUBERCULOSIS CONTROL;

EID: 84899441569     PISSN: None     EISSN: 17456673     Source Type: Journal    
DOI: 10.1186/1745-6673-9-9     Document Type: Review

References (56)

1. Infectious diseases in healthcare workers-an analysis of the standardised data set of a German compensation board. Nienhaus A, Kesavachandran C, Wendeler D, Haamann F, Dulon M, J Occup Med Toxicol 2012 7 8 10.1186/1745-6673-7-8 22553942
2. Social care and changes in occupational accidents and diseases-The situation in Eastern Europe in general and for skin diseases in particular. Von Hirschberg KR, Kähler B, Nienhaus A, J Occup Med Toxicol 2009 4 28 10.1186/1745-6673-4-28 19922633
3. RKI (Robert Koch Institut), Report on the epidemiology of tuberculosis in Germany for the year 2011 [Bericht zur Epidemiologie der Tuberkulose in Deutschland für 2011, report in German] Berlin: Robert Koch Institut 2013
4. Occupational risk of tuberculosis transmission in a low incidence area. Diel R, Seidler A, Nienhaus A, Rusch-Gerdes S, Niemann S, Respir Res 2005 6 1 35 45 10.1186/1465-9921-6-35 15831092
5. New recommendations for contact tracing in tuberculosis [Neue Empfehlungen für die Umgebungsuntersuchungen bei Tuberkulose, article in German]. Diel R, Loytved G, Nienhaus A, Castell S, Detjen A, Geerdes-Fenge H, Haas W, Hauer B, Konigstein B, Maffei D, Magdorf K, Priwitzer M, Zellweger JP, Loddenkemper R, Pneumologie 2011 65 359 378 10.1055/s-0030-1256439 21560113
6. Interferon-gamma release assays for tuberculosis screening of healthcare workers: a systematic review. Zwerling A, van den Hof S, Scholten J, Cobelens F, Menzies D, Pai M, Thorax 2012 67 1 62 70 10.1136/thx.2010.143180 21228420
7. Interferon-Y release assay vs. Tuberculin skin test for monitoring TB infection in healthcare workers. Nienhaus A, Ringshausen FC, Torres Costa J, Schablon A, Tripodi D, Expert Rev of Anti Infect Ther 2013 11 1 37 43 10.1586/eri.12.150
8. Interferon-γ release assays for the diagnosis of latent M. tuberculosis infection: A systematic review and meta-analysis. Diel R, Goletti D, Ferrara G, Bothamley G, Cirillo D, Kampmann B, Lange C, Losi M, Markova R, Migliori GB, Nienhaus A, Ruhwald M, Wagner D, Zellweger JP, Huitric E, Sandgren A, Manissero D, Eur Respir J 2011 37 88 99 10.1183/09031936.00115110 21030451
9. Evidence-based comparison of commercial interferon-gamma release assays for detecting active TB: a meta-analysis. Diel R, Loddenkemper R, Nienhaus A, Chest 2010 137 4 952 968 10.1378/chest.09-2350 20022968
10. Negative and positive predictive value of a whole-blood IGRA for developing active TB-an update. Diel R, Loddenkemper R, Niemann S, Meywald-Walter K, Nienhaus A, Am.J Respir Crit Care Med 2011 183 88 95 10.1164/rccm.201006-0974OC
11. Screening for tuberculosis and prediction of disease in Portuguese healthcare workers. Torres Costa J, Silva R, Ringshausen F, Nienhaus A, J Occup Med Toxicol 2011 6 19 10.1186/1745-6673-6-19 21658231
12. Systematic review of cost and cost-effectiveness of different TB-screening strategies. Nienhaus A, Schablon A, Costa JT, Diel R, BMC Health Serv Res 2011 11 247 10.1186/1472-6963-11-247 21961888
13. Interferon-gamma release assays for the tuberculosis serial testing of health care workers: a systematic review. Ringshausen FC, Schablon A, Nienhaus A, J Occup Med Toxico 2012 7 1 6 10.1186/1745-6673-7-6
14. Test variability of the QuantiFERON-TB gold in-tube assay in clinical practice. Metcalfe JZ, Cattamanchi A, McCulloch CE, Lew JD, Ha NP, Graviss EA, Am J Respir Crit Care Med 2013 187 2 206 211 10.1164/rccm.201203-0430OC 23103734
15. The prognosis of latent tuberculosis: can disease be predicted? Andersen P, Doherty TM, Pai M, Weldingh K, Trends Mol Med 2007 13 5 175 182 10.1016/j.molmed.2007.03.004 17418641
16. Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: An updated systematic review and meta-analysis. Steingart KR, Flores LL, Dendukuri N, Schiller I, Laal S, Ramsay A, Hopewell PC, Pai M, PLoS Med 2011 8 8 1001062 10.1371/journal.pmed.1001062 21857806
17. Transmission of Mycobacterium tuberculosis depending on the age and sex of source cases. Borgdorff MW, Nagelkerke NJ, de Haas PE, van Soolingen D, Am J Epidemiol 2001 154 10 934 43 10.1093/aje/154.10.934 11700248
18. Epidemiology of tuberculosis in Hamburg, Germany: long-term population-based analysis applying classical and molecular epidemiological techniques. Diel R, Schneider S, Meywald-Walter K, Ruf CM, Rüsch-Gerdes S, Niemann S, J Clin Microbiol 2002 40 532 539 10.1128/JCM.40.2.532-539.2002 11825968
19. The use of preventive therapy for tuberculosis infection in the United States-Recommendations of the Advisory Committee for Elimination of Tuberculosis. CDC-Centers for Disease Control, MMWR 1990 39 RR-8 9 12
20. The transmission of tuberculosis in the light of new molecular biological approaches. Seidler A, Nienhaus A, Diel R, Occup Environ Med 2004 61 96 102 10.1136/oem.2003.008573 14739374
21. A 13-year molecular epidemiological analysis of tuberculosis in San Francisco. Cattamanchi A, Hopewell PC, Gonzalez LC, Osmond DH, Kawamura LM, Daley CL, Int J Tuberc Lung Dis 2006 10 3 297 304 16562710
22. Risk of tuberculin conversation among healthcare workers and the adoption of preventive measures. Baussano I, Bugiani M, Carosso A, Mariano D, Pia Barocelli A, Tagna M, Cascio V, Piccioni P, Arossa W, Occup Environ Med 2007 64 61 66
23. Tuberculosis among health care workers. Baussano I, Nunn P, Williams B, Pivetta E, Bugiani M, Scano F, Emerg Infect Dis 2011 17 3 488 494 10.3201/eid1703.100947 21392441
24. Risk of tuberculosis infection and disease associated with work in health care settings. Menzies D, Joshi R, Pai M, Int J Tuberc Lung Dis 2007 11 6 593 605 17519089
25. Review of epidemiological studies on the occupational risk of tuberculosis in low-incidence areas. Seidler A, Nienhaus A, Diel R, Respiration 2005 72 4 431 446 10.1159/000086261 16088290
26. Healthcare workers with tuberculosis infected during work. De Vries G, Sebek MMGG, Lambregts-van W, Eur Respir J 2006 28 1216 1221 10.1183/09031936.06. 00039906 16807264
27. Tuberculosis in healthcare workers: a molecular epidemiologic study in San Francisco. Ong A, Rudoy I, Gonzalez LC, Creasman J, Kawamura LM, Daley C, Infect Control Hosp Epidemiol 2007 27 453 458
28. Serial IGRA testing of trainees in the healthcare sector in a country with low incidence for tuberculosis-a prospective cohort study. Schablon A, Peters C, Diel R, Diner G, Anskr U, Pankow W, Ringshausen FC, Nienhaus A, GMS Hygiene and Infection Control 2013 8 2 1 5
29. Evaluation of the interferon-gamma release assay in healthcare workers. Nienhaus A, Schablon A, Siano B, le Bacle C, Diel R, Int Arch Occup Environ Health 2008 81 295 300 17605033
30. Risk of latent TB infection in individuals employed in the healthcare sector in Germany: a multicentre prevalence study. Schablon A, Harling M, Diel R, Nienhaus A, BMC Infect Dis 2010 10 107 10.1186/1471-2334-10-107 20429957
31. Prevalence of latent tuberculosis infection in healthcare workers in geriatric care [Erhöhte Prävalenz der latenten Tuberkulose-Infektion bei Beschäftigten in der Geriatrie]. Nienhaus A, Schablon A, Loddenkemper R, Hauer B, Wolf N, Diel R, Pneumologie 2007 61 9 613 616 10.1055/s-2007-980104 17729212
32. Tuberculosis screening in Portuguese healthcare workers using the tuberculin skin test and the interferon-gamma release assay. Torres Costa J, Sá R, Cardoso MJ, Silva R, Ferreira J, Ribeiro C, Miranda M, Plácido JL, Nienhaus A, Eur Respir J 2009 34 1423 8 10.1183/09031936. 00053809 19948911
33. Evaluation of the tuberculin skin test and the interferon-gamma release assay for TB screening in French healthcare workers. Tripodi D, Brunet-Courtois B, Nael V, Audrain M, Chailleux E, Germaud P, Naudin F, Muller JY, Bourrut-Lacouture M, Durand-Perdriel MH, Gordeeff C, Guillaumin G, Houdebine M, Raffi F, Boutoille D, Biron C, Potel G, Roedlich C, Geraut C, Schablon A, Nienhaus A, J Occup Med Toxicol 2009 4 30 10.1186/1745-6673-4-30 19948042
34. Guidelines for preventing the transmission of Mycobacterium tuberculosis in Healthcare Settings. Jensen PA, Lambert LA, Iademarco MF, Ridzon R, MMWR 2005 54 RR-17 1 141
35. WHO policy on TB infection control in health-care facilities, congregate settings and household. WHO, WHO/HTM/TB 2009 419
36. Control of tuberculosis in health care settings. IUATLD-International Union against Tuberculosis and Lung Disease and the Tuberculosis Programme of the World Health Organization (WHO), Tuberc Lung Dis 1994 75 94 95
37. Tuberculosis Infection Control-Recommendations of the DZK [Infektionsprävention bei Tuberkulose-Empfehlungen des DZK. Article in German]. Ziegler R, Just HM, Castell S, Diel R, Gastmeier P, Haas W, Hauer B, Loytved G, Mielke M, Moser I, Nienhaus A, Richter E, Ruden H, Rusch-Gerdes S, Schaberg T, Wischnewski N, Loddenkemper R, Pneumologie 2012 6 269 282
38. Surgical face masks worn by patients with multidrug-resistant tuberculosis impact on infectivity of air on a hospital ward. Dharmadhikari AS, Mphahlele M, Stoltz A, Venter K, Mathebula R, Masotla T, Lubbe W, Pagano M, First M, Jensen PA, van der Walt M, Nardell EA, Am J Respir Crit Care Med 2012 185 1104 1109 10.1164/rccm.201107-1190OC 22323300
39. Canadian Collaborative Group in Nosocomial Transmission of Tuberculosis (2000). Hospital ventilation and risk of tuberculous infection in Canadian health care workers. Menzies D, Fanning A, Yuan L, FitzGerald JM, Ann Intern Med 2000 133 779 789 10.7326/0003-4819-133-10-200011210-00010 11085840
40. Comparison of five methods for fit-testing N95 filtering-facepice respirators. Coffey CC, Lawrence RB, Zhuang Z, Appl Occup Environ Hyg 2002 17 723 730 10.1080/10473220290107002 12363214
41. Repeat IGRA testing in Canadian health workers: conversions or unexplained variability? Zwerling A, Benedetti A, Cojocariu M, McIntosh F, Pietrangelo F, Behr MA, Schwartzmann K, Menzies D, Pai m, PLoS One 2013 8 1 54748 10.1371/journal.pone.0054748 23382955
42. European Centre for Disease Prevention and Control, Use of Interferon-Gamma Release Assays in Support of TB Diagnosis Stockholm: ECDC 2011
43. Serial testing with an interferon-gamma release assay in German healthcare workers. Schablon A, Harling M, Diel R, Ringshausen FC, Torres CJ, Nienhaus A, GMS Hyg Infect Control 2010 5 2
44. Serial testing with the interferon-gamma release assay in Portuguese healthcare workers. Torres Costa J, Silva R, Sa R, Cardoso MJ, Nienhaus A, Int Arch Occup Environ Health 2011 84 4 461 469 10.1007/s00420-010-0571-x 20721576
45. The effect of introducing IGRA to screen French healthcare workers for tuberculosis and potential conclusions for the work organisation. Moucaut A, Nienhaus A, Courtois B, Nael V, Longuenesse C, Ripault B, Rucay P, Moisan S, Roquelaure Y, Tripodi D, J Occup Med Toxicol 2013 8 12 10.1186/1745-6673-8-12 23647777
46. TB as an occupational disease. In Lange C, Migliori GB (Eds.), Tuberculosis (pp. 72-83). Nienhaus A, Schablon A, Ringshausen FC, Torres Costa J, Tripodi D, Diel R, Eur Respir Soc 2012 58 219 229
47. Challenges with QuantiFERON-TB Gold assay for large-scale, routine screening of U.S. healthcare workers. Slater ML, Welland G, Pai M, Parsonnet J, Banaei N, Am J Respir Crit Care Med 2013 188 8 1005 10 10.1164/rccm.201305- 0831OC 23978270
48. Canadian Tuberculosis Standards, Chapter 15 Prevention and control of tuberculosis transmission in healthcare and other settings-7th edition. Ogunremi T, Menzies D, Embil J, Can Thorac Soc 2013 http://www.respiratoryguidelines.ca
49. Isoniazid for preventing tuberculosis in non-HIV infected persons. Smieja MJ, Marchetti CA, Cook DJ, Smaill FM, Cochrane Database Syst 1999 1 D0011363
50. Recommendations for Therapy, Chemoprevention and Chemoprophylaxis of Tuberculosis in Adults and Children, German Central Committee against Tuberculosis (DZK), German Respiratory Society (DGP) [Empfehlungen zur Therapie, Chemoprävention und Chemoprophylaxe der Tuberkulose bei Erwachsenen und Kindern. Deutsches Zentralinstitut zur Bekämpfung der Tuberkulose (DZK), Deutsche Gesellschaft für Pneumologie (DGP) Article in German]. Schaberg T, Bauer T, Castell S, Dalhoff K, Detjen A, Diel R, Greinert U, Hauer B, Lange C, Magdorf K, Loddenkemper R, Pneumologie 2012 66 133 171 22328186
51. Toxic hepatitis with isoniazid and rifampin- a meta-analysis. Steele MA, Burk RF, DesPrez RM, Chest 1991 99 465 471 10.1378/chest.99.2.465 1824929
52. New regimens to prevent tuberculosis in adults with HIV infection. Masandjwa R, Hausler H, Ram M, McIntrye JA, Gray GE, Chaisson RE, N Engl J Med 2011 365 11 20 10.1056/NEJMoa1005136 21732833
53. Three months of once-weekly rifapentine and isoniazid for M tuberculosis infection. Shang N, Gordin F, Bliven-Sizemore E, Hackman J, Hamilton CD, Menzies D, Kerrigan A, Weis SE, Weiner M, Wing D, Conde MB, Bozeman L, Horsburgh CR Jr, Chaisson RE, TB Trials Consortium PREVENT TB Study Team, N Engl J Med 2011 2011 365 2155 2166
54. Recommendations for use of an isoniazid-rifapentine regimen with direct observation to treat latent Mycobacterium tuberculosis infection. CDC-Centers for Disease Control and Prevention, MMWR 2011 60 1650 1653 22157884
55. INRS-Institut National de Recherche et Sécurité Les maladies professionelle Paris: INRS 2012
56. Tuberculosis as occupational disease in healthcare workers [Tuberkulose als Berufskrankheit bei Beschäftigten im Gesundheitswesen, article in German]. Nienhaus A, Med Sach 2012 108 6 236 241