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Volumn 8, Issue 9, 2013, Pages
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A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.
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Author keywords
[No Author keywords available]
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Indexed keywords
4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE;
ACTIN;
AMINOQUINOLINE DERIVATIVE;
ANTINEOPLASTIC AGENT;
CDGAP PROTEIN, HUMAN;
GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN;
INDOLE DERIVATIVE;
N2,N4 BIS(2 METHYL 1H INDOL 5 YL)PYRIMIDINE 2,4 DIAMINE;
N2,N4-BIS(2-METHYL-1H-INDOL-5-YL)PYRIMIDINE-2,4-DIAMINE;
PHOSPHOPROTEIN;
PYRIMIDINE DERIVATIVE;
RAC1 PROTEIN;
RAC1 PROTEIN, HUMAN;
ANIMAL;
ARTICLE;
CELL MOTION;
CELL PROLIFERATION;
CHEMISTRY;
CYTOSKELETON;
DOSE RESPONSE;
DRUG ANTAGONISM;
DRUG SCREENING;
HUMAN;
MALE;
METABOLISM;
METASTASIS;
MOUSE;
PROSTATE TUMOR;
TUMOR CELL LINE;
TUMOR INVASION;
ACTINS;
AMINOQUINOLINES;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CELL LINE, TUMOR;
CELL MOVEMENT;
CELL PROLIFERATION;
CYTOSKELETON;
DOSE-RESPONSE RELATIONSHIP, DRUG;
GTPASE-ACTIVATING PROTEINS;
HUMANS;
INDOLES;
MALE;
MICE;
NEOPLASM INVASIVENESS;
NEOPLASM METASTASIS;
PHOSPHOPROTEINS;
PROSTATIC NEOPLASMS;
PYRIMIDINES;
RAC1 GTP-BINDING PROTEIN;
XENOGRAFT MODEL ANTITUMOR ASSAYS;
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EID: 84899435103
PISSN: None
EISSN: 19326203
Source Type: Journal
DOI: 10.1371/journal.pone.0074924 Document Type: Article |
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Times cited : (84)
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References (0)
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