-
1
-
-
79953038399
-
2011 ACCF/AHA/HRS focused updates incorporated into the ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines
-
Fuster V, Rydén LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. 2011 ACCF/AHA/HRS focused updates incorporated into the ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2011;123(10):e269- 367.
-
(2011)
Circulation
, vol.123
, Issue.10
-
-
Fuster, V.1
Rydén, L.E.2
Cannom, D.S.3
Crijns, H.J.4
Curtis, A.B.5
Ellenbogen, K.A.6
-
2
-
-
33747052359
-
Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence
-
Miyasaka Y, Barnes ME, Gersh BJ, Cha SS, Bailey KR, Abhayaratna WP, et al. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence. Circulation. 2006;114(2):119-25.
-
(2006)
Circulation
, vol.114
, Issue.2
, pp. 119-125
-
-
Miyasaka, Y.1
Barnes, M.E.2
Gersh, B.J.3
Cha, S.S.4
Bailey, K.R.5
Abhayaratna, W.P.6
-
3
-
-
0035854054
-
Validation of clinical classification schemes for predicting stroke: Results from the National Registry of Atrial Fibrillation
-
Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001;285(22):2864-70.
-
(2001)
JAMA
, vol.285
, Issue.22
, pp. 2864-2870
-
-
Gage, B.F.1
Waterman, A.D.2
Shannon, W.3
Boechler, M.4
Rich, M.W.5
Radford, M.J.6
-
4
-
-
77954392300
-
The CHADS2 score for stroke risk stratification in atrial fibrillation - Friend or foe?
-
Karthikeyan G, Eikelboom JW. The CHADS2 score for stroke risk stratification in atrial fibrillation - friend or foe? Thromb Haemost. 2010;104(1):45-8.
-
(2010)
Thromb Haemost
, vol.104
, Issue.1
, pp. 45-48
-
-
Karthikeyan, G.1
Eikelboom, J.W.2
-
5
-
-
79551645746
-
Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: Nationwide cohort study
-
Olesen JB, Lip GY, Hansen ML, Hansen PR, Tolstrup JS, Lindhardsen J, et al. Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study. BMJ. 2011;342:d124.
-
(2011)
BMJ
, vol.342
-
-
Olesen, J.B.1
Lip, G.Y.2
Hansen, M.L.3
Hansen, P.R.4
Tolstrup, J.S.5
Lindhardsen, J.6
-
6
-
-
76749163232
-
Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: The euro heart survey on atrial fibrillation
-
Lip GY, Nieuwlaat R, Pisters R, Lane DA, Crijns HJ. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest. 2010;137(2):263-72.
-
(2010)
Chest
, vol.137
, Issue.2
, pp. 263-272
-
-
Lip, G.Y.1
Nieuwlaat, R.2
Pisters, R.3
Lane, D.A.4
Crijns, H.J.5
-
7
-
-
78650414688
-
Identifying patients at high risk for stroke despite anticoagulation: A comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort
-
Lip GY, Frison L, Halperin JL, Lane DA. Identifying patients at high risk for stroke despite anticoagulation: a comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort. Stroke. 2010;41(12):2731-8.
-
(2010)
Stroke
, vol.41
, Issue.12
, pp. 2731-2738
-
-
Lip, G.Y.1
Frison, L.2
Halperin, J.L.3
Lane, D.A.4
-
8
-
-
78751543538
-
Stroke risk stratification in a "real-world" elderly anticoagulated atrial fibrillation population
-
Poli D, Lip GY, Antonucci E, Grifoni E, Lane D. Stroke risk stratification in a "real-world" elderly anticoagulated atrial fibrillation population. J Cardiovasc Electrophysiol. 2011;22(1):25-30.
-
(2011)
J Cardiovasc Electrophysiol
, vol.22
, Issue.1
, pp. 25-30
-
-
Poli, D.1
Lip, G.Y.2
Antonucci, E.3
Grifoni, E.4
Lane, D.5
-
9
-
-
80052094564
-
A new risk scheme to predict warfarin-associated hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study
-
Fang MC, Go AS, Chang Y, Borowsky LH, Pomernacki NK, Udaltsova N, et al. A new risk scheme to predict warfarin-associated hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study. J Am Coll Cardiol. 2011; 58(4):395-401.
-
(2011)
J Am Coll Cardiol
, vol.58
, Issue.4
, pp. 395-401
-
-
Fang, M.C.1
Go, A.S.2
Chang, Y.3
Borowsky, L.H.4
Pomernacki, N.K.5
Udaltsova, N.6
-
10
-
-
84871511861
-
New oral anticoagulants for stroke prevention in atrial fibrillation: Impact of gender, heart failure, diabetes mellitus and paroxysmal atrial fibrillation
-
Ahmad Y, Lip GY, Apostolakis S. New oral anticoagulants for stroke prevention in atrial fibrillation: impact of gender, heart failure, diabetes mellitus and paroxysmal atrial fibrillation. Expert Rev Cardiovasc Ther. 2012;10(12):1471-80.
-
(2012)
Expert Rev Cardiovasc Ther
, vol.10
, Issue.12
, pp. 1471-1480
-
-
Ahmad, Y.1
Lip, G.Y.2
Apostolakis, S.3
-
11
-
-
34548031359
-
The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
-
Stangier J, Rathgen K, Stahle H, Gansser D, Roth W. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol. 2007;64(3):292-303.
-
(2007)
Br J Clin Pharmacol
, vol.64
, Issue.3
, pp. 292-303
-
-
Stangier, J.1
Rathgen, K.2
Stahle, H.3
Gansser, D.4
Roth, W.5
-
12
-
-
0242384136
-
Targeting thrombin - Rational drug design from natural mechanisms
-
Huntington JA, Baglin TP. Targeting thrombin - rational drug design from natural mechanisms. Trends Pharmacol Sci. 2003;24(11):589-95.
-
(2003)
Trends Pharmacol Sci
, vol.24
, Issue.11
, pp. 589-595
-
-
Huntington, J.A.1
Baglin, T.P.2
-
13
-
-
38749131205
-
The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
-
Blech S, Ebner T, Ludwig-Schwellinger E, Stangier J, Roth W. The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metab Dispos. 2008;36(2):386-99.
-
(2008)
Drug Metab Dispos
, vol.36
, Issue.2
, pp. 386-399
-
-
Blech, S.1
Ebner, T.2
Ludwig-Schwellinger, E.3
Stangier, J.4
Roth, W.5
-
14
-
-
79954456496
-
Dabigatran etexilate: A new oral thrombin inhibitor
-
Hankey GJ, Eikelboom JW. Dabigatran etexilate: a new oral thrombin inhibitor. Circulation. 2011;123(13):1436-50.
-
(2011)
Circulation
, vol.123
, Issue.13
, pp. 1436-1450
-
-
Hankey, G.J.1
Eikelboom, J.W.2
-
15
-
-
84899446252
-
-
Published 4 November Accessed 8 Jan 2014
-
European Medicines Agency. Pradaxa: European public assessment report. Summary for the public. http://www.ema.europa.eu/ema/index.jsp?curl=pages/ medicines/human/medicines/000829/human-med-000981.jsp&mid= WC0b01ac058001d124. Published 4 November 2013. Accessed 8 Jan 2014.
-
(2013)
Pradaxa: European Public Assessment Report. Summary for the Public
-
-
-
16
-
-
17644400166
-
Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement
-
Stangier J, Eriksson BI, Dahl OE, Ahnfelt L, Nehmiz G, Stahle H, et al. Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement. J Clin Pharmacol. 2005;45(5):555-63.
-
(2005)
J Clin Pharmacol
, vol.45
, Issue.5
, pp. 555-563
-
-
Stangier, J.1
Eriksson, B.I.2
Dahl, O.E.3
Ahnfelt, L.4
Nehmiz, G.5
Stahle, H.6
-
18
-
-
66449099711
-
Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans
-
Weinz C, Schwarz T, Kubitza D, Mueck W, Lang D. Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans. Drug Metab Dispos. 2009;37(5):1056-64.
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.5
, pp. 1056-1064
-
-
Weinz, C.1
Schwarz, T.2
Kubitza, D.3
Mueck, W.4
Lang, D.5
-
19
-
-
84855712570
-
Pharmacodynamic and pharmacokinetic basics of rivaroxaban
-
Kreutz R. Pharmacodynamic and pharmacokinetic basics of rivaroxaban. Fundam Clin Pharmacol. 2012;26(1):27-32.
-
(2012)
Fundam Clin Pharmacol
, vol.26
, Issue.1
, pp. 27-32
-
-
Kreutz, R.1
-
20
-
-
55549139511
-
Dose-escalation study of the pharmacokinetics and pharmacodynamics of rivaroxaban in healthy elderly subjects
-
Kubitza D, Becka M, Roth A, Mueck W. Dose-escalation study of the pharmacokinetics and pharmacodynamics of rivaroxaban in healthy elderly subjects. Curr Med Res Opin. 2008;24(10):2757-65.
-
(2008)
Curr Med Res Opin
, vol.24
, Issue.10
, pp. 2757-2765
-
-
Kubitza, D.1
Becka, M.2
Roth, A.3
Mueck, W.4
-
21
-
-
29144518504
-
Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939 - An oral, direct Factor Xa inhibitor - After multiple dosing in healthy male subjects
-
Kubitza D, Becka M, Wensing G, Voith B, Zuehlsdorf M. Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939 - an oral, direct Factor Xa inhibitor - after multiple dosing in healthy male subjects. Eur J Clin Pharmacol. 2005;61(12):873-80.
-
(2005)
Eur J Clin Pharmacol
, vol.61
, Issue.12
, pp. 873-880
-
-
Kubitza, D.1
Becka, M.2
Wensing, G.3
Voith, B.4
Zuehlsdorf, M.5
-
22
-
-
78649289929
-
Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct factor Xa inhibitor
-
Kubitza D, Becka M, Mueck W, Halabi A, Maatouk H, Klause N, et al. Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct factor Xa inhibitor. Br J Clin Pharmacol. 2010;70(5):703-12.
-
(2010)
Br J Clin Pharmacol
, vol.70
, Issue.5
, pp. 703-712
-
-
Kubitza, D.1
Becka, M.2
Mueck, W.3
Halabi, A.4
Maatouk, H.5
Klause, N.6
-
26
-
-
84899446252
-
-
Published 24 June Accessed 30 Sept 2013
-
European Medicines Agency. Xarelto European public assessment report summary for the public. http://www.ema.europa.eu/docs/en-GB/document-library/ EPAR---Summary-for-the-public/human/000944/WC500057109.pdf. Published 24 June 2013. Accessed 30 Sept 2013.
-
(2013)
Xarelto European Public Assessment Report Summary for the Public
-
-
-
27
-
-
58149458160
-
Apixaban metabolism and pharmacokinetics after oral administration to humans
-
Raghavan N, Frost CE, Yu Z, He K, Zhang H, Humphreys WG, et al. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos. 2009;37(1): 74-81.
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.1
, pp. 74-81
-
-
Raghavan, N.1
Frost, C.E.2
Yu, Z.3
He, K.4
Zhang, H.5
Humphreys, W.G.6
-
28
-
-
84871294411
-
Management of atrial fibrillation: Direct factor IIa and Xa inhibitors or "warfarin shotgun"?
-
Halperin JL, Goyette RE. Management of atrial fibrillation: direct factor IIa and Xa inhibitors or "warfarin shotgun"? Mt Sinai J Med. 2012;79(6):705-20.
-
(2012)
Mt Sinai J Med
, vol.79
, Issue.6
, pp. 705-720
-
-
Halperin, J.L.1
Goyette, R.E.2
-
31
-
-
84885929631
-
Bioavailability and safety of the factor Xa inhibitor edoxaban and the effects of quinidine in healthy subjects
-
Published online September at
-
Matsushima N, Lee F, Sato T, Weiss D, Mendell J. Bioavailability and safety of the factor Xa inhibitor edoxaban and the effects of quinidine in healthy subjects. Clin Pharmacol Drug Dev. Published online September 2013 at http://onlinelibrary.wiley.com/doi/10.1002/cpdd.53/full.
-
(2013)
Clin Pharmacol Drug Dev
-
-
Matsushima, N.1
Lee, F.2
Sato, T.3
Weiss, D.4
Mendell, J.5
-
32
-
-
49849099533
-
DU-176b, a potent and orally active factor Xa inhibitor: In vitro and in vivo pharmacological profiles
-
Furugohri T, Isobe K, Honda Y, Kamisato-Matsumoto C, Sugiyama N, Nagahara T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008;6(9):1542-9.
-
(2008)
J Thromb Haemost
, vol.6
, Issue.9
, pp. 1542-1549
-
-
Furugohri, T.1
Isobe, K.2
Honda, Y.3
Kamisato-Matsumoto, C.4
Sugiyama, N.5
Nagahara, T.6
-
33
-
-
79961095222
-
Edoxaban: Pharmacological principles, preclinical and early-phase clinical testing
-
Partida RA, Giugliano RP. Edoxaban: pharmacological principles, preclinical and early-phase clinical testing. Future Cardiol. 2011;7(4):459-70.
-
(2011)
Future Cardiol
, vol.7
, Issue.4
, pp. 459-470
-
-
Partida, R.A.1
Giugliano, R.P.2
-
34
-
-
84869109465
-
Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans
-
Bathala MS, Masumoto H, Oguma T, He L, Lowrie C, Mendell J. Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos. 2012;40(12):2250-5.
-
(2012)
Drug Metab Dispos
, vol.40
, Issue.12
, pp. 2250-2255
-
-
Bathala, M.S.1
Masumoto, H.2
Oguma, T.3
He, L.4
Lowrie, C.5
Mendell, J.6
-
36
-
-
64349107688
-
Rationale and design of RE-LY: Randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran
-
Ezekowitz MD, Connolly S, Parekh A, Reilly PA, Varrone J, Wang S, et al. Rationale and design of RE-LY: randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran. Am Heart J. 2009;157(5):805-10, 10 e1-2.
-
(2009)
Am Heart J
, vol.157
, Issue.5
-
-
Ezekowitz, M.D.1
Connolly, S.2
Parekh, A.3
Reilly, P.A.4
Varrone, J.5
Wang, S.6
-
37
-
-
70349306707
-
Dabigatran versus warfarin in patients with atrial fibrillation
-
Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361(12):1139-51.
-
(2009)
N Engl J Med
, vol.361
, Issue.12
, pp. 1139-1151
-
-
Connolly, S.J.1
Ezekowitz, M.D.2
Yusuf, S.3
Eikelboom, J.4
Oldgren, J.5
Parekh, A.6
-
38
-
-
80052592404
-
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
-
Patel MR, Mahaffey KW, Garg J, Pan G, Singer DE, Hacke W, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. New Engl J Med. 2011;365(10):883-91.
-
(2011)
New Engl J Med
, vol.365
, Issue.10
, pp. 883-891
-
-
Patel, M.R.1
Mahaffey, K.W.2
Garg, J.3
Pan, G.4
Singer, D.E.5
Hacke, W.6
-
39
-
-
85058721877
-
Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation: Rationale and design of the ROCKET AF study
-
Rocket AF Study Investigators
-
Rocket AF Study Investigators. Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation: rationale and design of the ROCKET AF study. Am Heart J. 2010;159(3):340-7 e1.
-
(2010)
Am Heart J
, vol.159
, Issue.3
-
-
-
40
-
-
80052825103
-
Apixaban versus warfarin in patients with atrial fibrillation
-
Granger CB, Alexander JH, McMurray JJV, Lopes RD, Hylek EM, Hanna M, et al. Apixaban versus warfarin in patients with atrial fibrillation. New Engl J Med. 2011;365(11):981-92.
-
(2011)
New Engl J Med
, vol.365
, Issue.11
, pp. 981-992
-
-
Granger, C.B.1
Alexander, J.H.2
McMurray, J.J.V.3
Lopes, R.D.4
Hylek, E.M.5
Hanna, M.6
-
41
-
-
77649249878
-
Apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial: Design and rationale
-
Lopes RD, Alexander JH, Al-Khatib SM, Ansell J, Diaz R, Easton JD, et al. Apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial: design and rationale. Am Heart J. 2010;159(3):331-9.
-
(2010)
Am Heart J
, vol.159
, Issue.3
, pp. 331-339
-
-
Lopes, R.D.1
Alexander, J.H.2
Al-Khatib, S.M.3
Ansell, J.4
Diaz, R.5
Easton, J.D.6
-
42
-
-
77957932391
-
Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: Design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF-TIMI 48)
-
Ruff CT, Giugliano RP, Antman EM, Crugnale SE, Bocanegra T, Mercuri M, et al. Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation- Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF-TIMI 48). Am Heart J. 2010;160(4):635-41.
-
(2010)
Am Heart J
, vol.160
, Issue.4
, pp. 635-641
-
-
Ruff, C.T.1
Giugliano, R.P.2
Antman, E.M.3
Crugnale, S.E.4
Bocanegra, T.5
Mercuri, M.6
-
43
-
-
84888362796
-
Edoxaban versus warfarin in patients with atrial fibrillation
-
Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, et al. Edoxaban versus warfarin in patients with atrial fibrillation. New Engl J Med. 2013;369(22):2093-104.
-
(2013)
New Engl J Med
, vol.369
, Issue.22
, pp. 2093-2104
-
-
Giugliano, R.P.1
Ruff, C.T.2
Braunwald, E.3
Murphy, S.A.4
Wiviott, S.D.5
Halperin, J.L.6
-
44
-
-
84869083231
-
Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: A secondary analysis of a randomised controlled trial
-
Lopes RD, Al-Khatib SM, Wallentin L, Yang H, Ansell J, Bahit MC, et al. Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial. Lancet. 2012;380(9855):1749-58.
-
(2012)
Lancet
, vol.380
, Issue.9855
, pp. 1749-1758
-
-
Lopes, R.D.1
Al-Khatib, S.M.2
Wallentin, L.3
Yang, H.4
Ansell, J.5
Bahit, M.C.6
-
45
-
-
84860796230
-
Warfarin therapeutic monitoring: Is 70% time in the therapeutic range the best we can do?
-
Lader E, Martin N, Cohen G, Meyer M, Reiter P, Dimova A, et al. Warfarin therapeutic monitoring: is 70% time in the therapeutic range the best we can do? J Clin Pharm Ther. 2012;37(4):375-7.
-
(2012)
J Clin Pharm Ther
, vol.37
, Issue.4
, pp. 375-377
-
-
Lader, E.1
Martin, N.2
Cohen, G.3
Meyer, M.4
Reiter, P.5
Dimova, A.6
-
46
-
-
65449163045
-
Meta-analysis to assess the quality of warfarin control in atrial fibrillation patients in the United States
-
Baker WL, Cios DA, Sander SD, Coleman CI. Meta-analysis to assess the quality of warfarin control in atrial fibrillation patients in the United States. J Manag Care Pharm. 2009;15(3):244-52.
-
(2009)
J Manag Care Pharm
, vol.15
, Issue.3
, pp. 244-252
-
-
Baker, W.L.1
Cios, D.A.2
Sander, S.D.3
Coleman, C.I.4
-
47
-
-
80054737027
-
The business case for quality improvement oral anticoagulation for atrial fibrillation
-
Rose AJ, Berlowitz DR, Ash AS, Ozonoff A, Hylek EM, Gold-haber- Fiebert JD. The business case for quality improvement oral anticoagulation for atrial fibrillation. Circ Cardiovasc Qual Outcomes. 2011;4(4):416-24.
-
(2011)
Circ Cardiovasc Qual Outcomes
, vol.4
, Issue.4
, pp. 416-424
-
-
Rose, A.J.1
Berlowitz, D.R.2
Ash, A.S.3
Ozonoff, A.4
Hylek, E.M.5
Gold-haber- Fiebert, J.D.6
-
48
-
-
77956977472
-
Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: An analysis of the RE-LY trial
-
Wallentin L, Yusuf S, Ezekowitz MD, Alings M, Flather M, Franzosi MG, et al. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial. Lancet. 2010;376(9745):975-83.
-
(2010)
Lancet
, vol.376
, Issue.9745
, pp. 975-983
-
-
Wallentin, L.1
Yusuf, S.2
Ezekowitz, M.D.3
Alings, M.4
Flather, M.5
Franzosi, M.G.6
-
49
-
-
84878659651
-
Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: Data from the ROCKET AF clinical trial
-
Singer DE, Hellkamp AS, Piccini JP, Mahaffey KW, Lokhnygina Y, Pan G, et al. Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: data from the ROCKET AF clinical trial. J Am Heart Assoc. 2013;2(1):e000067.
-
(2013)
J Am Heart Assoc
, vol.2
, Issue.1
-
-
Singer, D.E.1
Hellkamp, A.S.2
Piccini, J.P.3
Mahaffey, K.W.4
Lokhnygina, Y.5
Pan, G.6
-
50
-
-
84878535107
-
Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation
-
Wallentin L, Lopes RD, Hanna M, Thomas L, Hellkamp A, Nepal S, et al. Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation. Circulation. 2013;127(22):2166-76.
-
(2013)
Circulation
, vol.127
, Issue.22
, pp. 2166-2176
-
-
Wallentin, L.1
Lopes, R.D.2
Hanna, M.3
Thomas, L.4
Hellkamp, A.5
Nepal, S.6
-
51
-
-
84896117299
-
Ezekowitz MD Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: A meta-analysis of randomised trials
-
doi:10.1016/S0140-6736(13)62343-0. [Epub ahead of print]
-
Ruff CT, Giugliano RP, Braunwald E, Hoffman EB, Deenadayalu N, Ezekowitz MD Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2013. doi:10.1016/S0140-6736(13)62343-0. [Epub ahead of print].
-
(2013)
Lancet
-
-
Ruff, C.T.1
Giugliano, R.P.2
Braunwald, E.3
Hoffman, E.B.4
Deenadayalu, N.5
-
52
-
-
79952301326
-
Apixaban in patients with atrial fibrillation
-
Connolly SJ, Eikelboom J, Joyner C, Diener H-C, Hart R, Golitsyn S, et al. Apixaban in patients with atrial fibrillation. New Engl J Med. 2011;364(9):806-17.
-
(2011)
New Engl J Med
, vol.364
, Issue.9
, pp. 806-817
-
-
Connolly, S.J.1
Eikelboom, J.2
Joyner, C.3
Diener, H.-C.4
Hart, R.5
Golitsyn, S.6
-
53
-
-
84867183673
-
The prevention and treatment of missing data in clinical trials
-
Little RJ, D'Agostino R, Cohen ML, Dickersin K, Emerson SS, Farrar JT, et al. The prevention and treatment of missing data in clinical trials. N Engl J Med. 2012;367(14):1355-60.
-
(2012)
N Engl J Med
, vol.367
, Issue.14
, pp. 1355-1360
-
-
Little, R.J.1
D'Agostino, R.2
Cohen, M.L.3
Dickersin, K.4
Emerson, S.S.5
Farrar, J.T.6
-
54
-
-
0037006675
-
Sample size slippages in randomised trials: Exclusions and the lost and wayward
-
Schulz KF, Grimes DA. Sample size slippages in randomised trials: exclusions and the lost and wayward. Lancet. 2002; 359(9308):781-5.
-
(2002)
Lancet
, vol.359
, Issue.9308
, pp. 781-785
-
-
Schulz, K.F.1
Grimes, D.A.2
-
55
-
-
79960936716
-
-
Boehringer Ingelheim. 72 August
-
Boehringer Ingelheim. Pradaxa (dabigatran etexilate): advisory committee briefing document. 72 August 2010. http://www.fda.gov/downloads/ AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/ CardiovascularandRenalDrugsAdvisoryCommittee/UCM226009.pdf.
-
(2010)
Pradaxa (Dabigatran Etexilate): Advisory Committee Briefing Document
-
-
-
56
-
-
84873378766
-
Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: Analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation)
-
Patel MR, Hellkamp AS, Lokhnygina Y, Piccini JP, Zhang Z, Mohanty S, et al. Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation). J Am Coll Cardiol. 2013;61(6):651-8.
-
(2013)
J Am Coll Cardiol
, vol.61
, Issue.6
, pp. 651-658
-
-
Patel, M.R.1
Hellkamp, A.S.2
Lokhnygina, Y.3
Piccini, J.P.4
Zhang, Z.5
Mohanty, S.6
-
57
-
-
84899462040
-
-
Center for Drug Evaluation and Research. 17 December cited 2013 May 3, 2013
-
Center for Drug Evaluation and Research. Application number: 202155Orig1s000. Apixaban clinical review addendum. 17 December 2011 [cited 2013 May 3, 2013]. http://www.accessdata.fda.gov/drugsatfda-docs/nda/2012/ 202155Orig1s000MedR.pdf.
-
(2011)
Application Number: 202155Orig1s000. Apixaban Clinical Review Addendum
-
-
-
58
-
-
45949103309
-
Pharmacology and management of the vitamin K antagonists
-
American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
-
Ansell J, Hirsh J, Hylek E, Jacobson A, Crowther M, Palareti G. Pharmacology and management of the vitamin K antagonists, American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6-suppl): 160S-98S.
-
(2008)
Chest
, vol.133
, Issue.6 SUPPL.
-
-
Ansell, J.1
Hirsh, J.2
Hylek, E.3
Jacobson, A.4
Crowther, M.5
Palareti, G.6
-
59
-
-
0027958326
-
The international normalized ratio. A guide to understanding and correcting its problems
-
Hirsh J, Poller L. The international normalized ratio. A guide to understanding and correcting its problems. Arch Intern Med. 1994;154(3):282-8.
-
(1994)
Arch Intern Med
, vol.154
, Issue.3
, pp. 282-288
-
-
Hirsh, J.1
Poller, L.2
-
60
-
-
84880370076
-
The long term multi-center observational study of dabigatran treatment in patients with atrial fibrillation: (RELY-ABLE) study
-
Connolly SJ, Wallentin L, Ezekowitz MD, Eikelboom JW, Oldgren J, Reilly PA, et al. The long term multi-center observational study of dabigatran treatment in patients with atrial fibrillation: (RELY-ABLE) study. Circulation. 2013;128(3):237-43.
-
(2013)
Circulation
, vol.128
, Issue.3
, pp. 237-243
-
-
Connolly, S.J.1
Wallentin, L.2
Ezekowitz, M.D.3
Eikelboom, J.W.4
Oldgren, J.5
Reilly, P.A.6
-
62
-
-
84862907587
-
Rivaroxaban in patients with a recent acute coronary syndrome
-
Mega JL, Braunwald E, Wiviott SD, Bassand J-P, Bhatt DL, Bode C, et al. Rivaroxaban in patients with a recent acute coronary syndrome. N Engl J Med. 2012;366(1):9-19.
-
(2012)
N Engl J Med
, vol.366
, Issue.1
, pp. 9-19
-
-
Mega, J.L.1
Braunwald, E.2
Wiviott, S.D.3
Bassand, J.-P.4
Bhatt, D.L.5
Bode, C.6
-
63
-
-
0038345858
-
Is there a hypercoagulable phase during initiation of antithrombotic therapy with oral anticoagulants in patients with atrial fibrillation?
-
Zeuthen EL, Lassen JF, Husted SE. Is there a hypercoagulable phase during initiation of antithrombotic therapy with oral anticoagulants in patients with atrial fibrillation? Thromb Res. 2003;109(5-6):241-6.
-
(2003)
Thromb Res
, vol.109
, Issue.5-6
, pp. 241-246
-
-
Zeuthen, E.L.1
Lassen, J.F.2
Husted, S.E.3
-
64
-
-
77953787643
-
Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers
-
Ogata K, Mendell-Harary J, Tachibana M, Masumoto H, Oguma T, Kojima M, et al. Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers. J Clin Pharmacol. 2010;50(7):743-53.
-
(2010)
J Clin Pharmacol
, vol.50
, Issue.7
, pp. 743-753
-
-
Ogata, K.1
Mendell-Harary, J.2
Tachibana, M.3
Masumoto, H.4
Oguma, T.5
Kojima, M.6
-
65
-
-
84899450077
-
-
Cardiovascular and Renal Drugs Advisory Committee. 8 September
-
Cardiovascular and Renal Drugs Advisory Committee. Rivaroxaban (XARELTO), 8 September 2011.
-
(2011)
Rivaroxaban (XARELTO)
-
-
-
66
-
-
80955182268
-
Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabigatran or warfarin in relation to the CHADS2 score: A subgroup analysis of the RE-LY trial
-
Oldgren J, Alings M, Darius H, Diener HC, Eikelboom J, Ezekowitz MD, et al. Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabigatran or warfarin in relation to the CHADS2 score: a subgroup analysis of the RE-LY trial. Ann Intern Med. 2011;155(10):660-7, W204.
-
(2011)
Ann Intern Med
, vol.155
, Issue.10
-
-
Oldgren, J.1
Alings, M.2
Darius, H.3
Diener, H.C.4
Eikelboom, J.5
Ezekowitz, M.D.6
-
67
-
-
79959550517
-
Standardized bleeding definitions for cardiovascular clinical trials: A consensus report from the Bleeding Academic Research Consortium
-
Mehran R, Rao SV, Bhatt DL, Gibson CM, Caixeta A, Eikelboom J, et al. Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium. Circulation. 2011; 123(23):2736-47.
-
(2011)
Circulation
, vol.123
, Issue.23
, pp. 2736-2747
-
-
Mehran, R.1
Rao, S.V.2
Bhatt, D.L.3
Gibson, C.M.4
Caixeta, A.5
Eikelboom, J.6
|