Genotoxicity biomarkers in aquatic bioindicators

Current Zoology

Volumn 60, Issue 2, 2014, Pages 273-284

  Bolognesi, Claudia ^a   Cirillo, Silvia ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Aquatic animals; Bioindicator; Biomarker; Bivalve; Comet assay; Genotoxicity; Micronucleus test; Mussel

Indexed keywords

EID: 84899154757     PISSN: 16745507     EISSN: None     Source Type: Journal    
DOI: 10.1093/czoolo/60.2.273     Document Type: Article

References (85)

1. Alamri OD, Cundy AB, Di Y, Jha AN, Rotchell JM, 2012. Ionizing radiation-induced DNA damage response identified in marine mussels Mytilus spp. Environ. Pollution 168: 107-112.
2. Ali LD, Alarifi S, Kumar S, Ahamed M, Siddiqui MA, 2012. Oxidative stress and genotoxic effect of zinc oxide nanoparticles in freshwater snail Lymnaea luteola. Aquat Toxicol 124/125: 83-90.
3. Almeida C, Pereira CG, Gomes T, Cardoso C, Bebianno MJ et al., 2013. Genotoxicity in two bivalve species from a coastal lagoon in the south of Portugal. Mar. Environ. Res. 89:29-38.
4. Barsiene J, Lazutka J, Syvokiene J, Dedonyte V, Rybakovas A et al., 2004. Analysis of micronuclei in blue mussels and fish from the Baltic and North Seas. Environ. Toxicol. 19: 365-371.
5. Barsiene J, Schiedek D, Rybakovas A, Syvokiene J, Kopecka J et al., 2006. Cytogenetic and cytotoxic effects in gill cells of the blue mussel Mytilus spp. from different zones of the Baltic Sea. Mar. Pollut. Bull. 53. 469-478.
6. Baršiene J, Rybakovas A, Garnaga G, Andreikenaite L, 2012. Environmental genotoxicity and cytotoxicity studies in mussels before and after an oil spill at the marine oil terminal in the Baltic Sea. Environ. Monit. Assess. 184:2067-78
7. Batel R, Vukmirovic M, Jacsic Z, Bihari N, 1994. Impact of pollution on DNA fragmentation in marine invertebrates. In: Miiller WEG ed. Use of Aquatic Invertebrates as Tools for Monitoring the Environmental Hazards. New York: Gustav Fischer Verlag, Stuttgart-Jena, 109-117.
8. Batel R, Jakšic Z, Bihari N, Hamer B, Fafandel M et al., 1999. A microplate assay for DNA damage determination (Fast Micromethod) in cell suspensions and solid tissues. Anal. Biochem. 270: 195-200.
9. Bistodeau TJ, Barber LB, Bartell SE, Cediel RA, Grove KJ, 2006. Larval exposure to environmentally relevant mixtures of alkylphenolethoxylates reduces reproductive competence in male fathead minnows. Aquat. Toxicol.79(3): 268-77.
10. Bocchetti R, Fattorini D, Pisanelli B, Macchia S, Oliviero L et al., 2008. Contaminant accumulation and biomarker responses in caged mussels Mytilus galloprovincialis to evaluate bioavailability and toxicological effects of remobilized chemicals during dredging and disposal operations in harbour areas. Aquat. Toxicol. 89: 257-266.
11. Boleda MR, Galceran MT, Ventura F, 2009. Monitoring of opiates, cannabinoids and their metabolites in wastewater, surface water and finished water in Catalonia, Spain. Water Res. 43: 126-36.
12. Bolognesi C, 1990. Carcinogenic and mutagenic effects of pollutants in marine organisms: A review. In: Grandjean E ed. Carcinogenic, Mutagenic, and Teratogenic Marine Pollutants: Impact on Human Healt and the Environment. The Woodland: Portfolio Publishing Company, 67-83.
13. Bolognesi C, Rabboni R, Roggeri P, 1996. Genotoxicity biomarkers in M. galloprovincialis as indicators of marine pollutants. Comp. Biochem. Physiol. 113C: 319-323.
14. Bolognesi C, Landini E, Roggieri P, Fabbri R, Viarengo A, 1999. Genotoxicity biomarkers in the assessment of heavy metal effects in mussels: Experimental studies. Environ. Mol. Mutagen. 33: 287-29.
15. Bolognesi C, Frenzilli G, Lasagna C, Perrone E, Roggieri P, 2004. Genotoxicity biomarkers in Mytilus galloprovincialis: Wild versus caged mussels. Mutat. Res. 552: 187-196.
16. Bolognesi C, Perrone E, Roggieri P, Sciutto A, 2006. Bioindicators in monitoring long term genotoxic impact of spill: Haven case study. Mar. Environ. Res: 65: S287-S291.
17. Bolognesi C, Hayashi M, 2011. Micronucleus assay in aquatic animals. Mutagenesis 26: 205-13
18. Bolognesi C, Fenech M, 2012. Mussel micronucleus cytome assay. Nat. Protoc. 17: 1125-37
19. Canty MN, Hutchinson TH, Brown RJ, Jones MB, Jha AN, 2009. Linking genotoxic responses with cytotoxic and behavioural or physiological consequences: Differential sensitivity of echinoderms Asterias rubens and marine mollusks Mytilus edulis. Aquat. Toxicol. 94: 68-76.
20. Cong Y, Banta GT, Selck H, Berhanu D, Valsami-Jones E et al., 2011. Toxic effects and bioaccumulation of nano, micron- and ionic-Ag in the polychaete Nereis diversicolor. Aquat. Toxicol. 105: 403-411.
21. Dailianis S, Domouhtsidou GP, Raftopoulou E, Kaloyianni M, Dimitriadis VK, 2003. Evaluation of neutral red retention assay, micronucleus test, acetylcholinesterase activity and a signal transduction molecule (cAMP) in tissues of Mytilus galloprovincialis (L.), in pollution monitoring. Mar. Environ. Res. 56: 443-470.
22. Dallas LJ, Cheung VV, Fisher AS, Jha AN, 2013. Relative sensitivity of two marine bivalves for detection of genotoxic and cytotoxic effects: A field assessment in the Tamar Estuary, South West England. Environ Monit Assess. 185:3397-412.
23. Devaux A, Fiat L, Gillet C, Bony S, 2011. Reproduction impairment following paternal genotoxin exposure in brown trout Salmo trutta and Arctic charr Salvelinus alpinus. Aquat Toxicol. 101: 405-411.
24. Díaz A, Carro S, Santiago L, Estévez J, Guevara C et al., 2009. Estimates of DNA strand breakage in bottlenose dolphin Tursiops truncates leukocytes measured with the Comet and DNA diffusion assays Genet. Mol. Biol. 32: 367-372
25. Dixon DR, Pruski AM, Dixon LRJ, Jha AN, 2002. Marine invertebrate ecogenotoxicology: A methodological overview Mutagenesis 17: 495-507.
26. Dolcetti L, Venier P, 2002. Susceptibility to genetic damage and cell types in Mediterranean mussels. Mar. Environ. Res. 54: 487-491.
27. Dolcetti L, Zuanna LD, Venier P, 2002. DNA adducts in mussels and fish exposed to bulky genotoxic compounds. Mar. Environ. Res. 54: 481-486.
28. Eganhouse RP, Sherblom PM, 2001. Anthropogenic organic contaminants in the effluent of a combined sewer overflow: Impact on Boston Harbour. Marine Environ. Res. 51:51-74.
29. Fairbairn DW, Olive PL, O'Neil KL, 1995. The comet assay: A comprehensive revierw. Mutation Research 339: 37-59.
30. Feng S, Kong Z, Wang X, Zhao L, Peng P, 2004. Acute toxicity and genotoxity of two novel pesticides on amphibian Rana N. Hallowell Chemosphere 56: 457-463.
31. Fernández B, Campillo JA, Martínez-Gómez C, Benedicto J, 2011. Micronuclei and other nuclear abnormalities in mussels Mytilus galloprovincialis as biomarkers of cyto-genotoxic pollution in mediterranean waters. Environ. Mol. Mutagen. 52: 479-91.
32. Frenzilli G, Bocchetti R, Pagliarecci M, Nigro M, Annarumma F., et al., 2004. Time-course evaluation of ROS-mediated toxicity in mussels Mytilus galloprovincialis during a field translocation experiment. Mar. Environ. Res. 58: 609-613.
33. Frenzilli G, Nigro M, Lyons BP, 2009. The Comet assay for the evaluation of genotoxic impact in aquatic environments. Mutation Research 681: 80-92.
34. Frenzilli G, Lyons BP, 2013. The comet assay in marine animals. Genotoxicity Assessment: Methods and Protocols. Methods in Mol. Biol. 1044: 363-372.
35. Giesy JP, Pierens SL, Snyder EM, Miles-Richardson S, Kramer VJ et al., 2000. Effects of 4-nonylphenol on fecundity and biomarkers of estrogenicity in fathead minnows Pimephales promelas. Environ. Toxicol. Chem. 19:1368-1377.
36. Ginebreda A, Kuzmanovic M, Guasch H, López de Alda M, López-Doval JC et al., 2014 Assessment of multi-chemical pollution in aquatic ecosystems using toxic units: Compound prioritization, mixture characterization and relationships with biological descriptors. Sci. Total Environ. 468/469: 715-723
37. Gomiero A, Da Ros L, Nasci C, Meneghetti F, Spagnolo A, et al., 2011. Integrated use of biomarkers in the mussel Mytilus galloprovincialis for assessing off-shore gas platforms in the Adriatic Sea: Results of a two-year biomonitoring program. Mar. Pollut. Bull. 62:2483-95.
38. Gorbi S, Virno Lamberti C, Notti A, Benedetti M, Fattorini D et al., 2008. An ecotoxicological protocol with caged mussels Mytilus galloprovincialis for monitoring the impact of an offshore platform in the Adriatic sea. Mar. Environ. Res. 65:34-49.
39. Guecheva T, Henriques JAP, Erdtmann B, 2001. Genotoxic effects of copper sulphate in freshwater planarian in vivo, studied with the single-cell gel test (comet assay) Mutat. Res. 497: 19-27.
40. Halldorsson HP, Ericson G, Svavarsson J, 2004. DNA strand breakage in mussels Mytilus edulis L. deployed in intertidal and subtidal zone in Reykjavik harbor. Mar. Environ. Res. 58 763-767.
41. Harvey JS, Lyons BP, Page TS, Stewart C, Parry JM, 1999. An assessment of the genotoxic impact of the sea empress oil spill by the measurement of DNA adduct levels in selected invertebrate and vertebrate species. Mutat. Res. 441: 103-114.
42. Hayashi M, Ueda T, Uyeno K, Wada K, Kinae N et al., 1998. Development of genotoxicity assay systems that use aquatic organisms. Mutat. Res. 399: 125-133.
43. Hose JE, 1994. Large scale genotoxicity assessment in the marine environment. Environ. Health Perspec. 102: 29-32.
44. Izquierdo JI, Machado G, Ayllon F, d'Amico VL, Bala LO et al., 2003. Assessing pollution in coastal ecosystems: A preliminary survey using the micronucleus test in the mussel Mytilus edulis. Ecotoxicol. Environ. Saf. 55: 24-29.
45. Kalpaxis DL, Theos C, Xaplanteri MA, Dinos GP, Catsiki AV, 2004. Biomonitoring of Gulf of Patras, N. Peloponnesus, Greece: Application of a biomarker suite including evaluation of translation efficiency in Mytilus galloprovincialis cells. Environ. Res. 94: 211-220.
46. Kima GB, Lee RF, 2004. Effects of genotoxic compounds on DNA and development of early and late grass shrimp embryo stages. Mar. Environ. Res. 57: 329-338.
47. Klobučar G, Štambuk A, Hylland KI, Pavlica M, 2008. Detection of DNA damage in haemocytes of Mytilus galloprovincialis in the coastal ecosystems of Kaštela and Trogir bays Croatia. Sci. Total Environ. 405 330-337.
48. Kohn KW, Erickson LC, Ewig RAG, Friedman CA, 1976. Fractionation of DNA from mammalian cells by alkalin elution. Biochemistry. 15: 4629-4637.
49. Kuzmick DM, Mitchelmore CL, Hopkins WA, Rowe CL, 2006. Effects of coal combustion residues on survival, antioxidant potential, and genotoxicity resulting from full-lifecycle exposure of grass shrimp Palaemonetes pugio Holthiu. Sci. Total Environ. 373: 420-430.
50. Jha AN, 2008. Ecotoxicological application and significance of the comet assay. Mutagenesis 23: 207-221.
51. Lacaze E, Geffard O, Bony S, Devaux A, 2010. Genotoxicity assessment in the amphipod Gammarus fossarum by use of the alkaline Comet assay Mutat. Res. 700: 32-38.
52. Lacaze E, Geffard O, Goyet D, Bony S, Devaux A, 2011. Linking genotoxic responses in Gammarus fossarum germ cells with reproduction impairment, using the Comet assay. Environ. Res. 111: 626-634.
53. Laffon B, Rabade T, Pasaro E, Mendez J, 2006. Monitoring of the impact of Prestige oil spill on Mytilus galloprovincialis from Galician coast. Environ. Int. 32: 342-348.
54. Lee HB, Peart TE, 2000. Bisphenol A contamination in Canadian municipal and industrial wastewater and sludge samples. Water Qual.Res. J. Can. 35: 283-298.
55. Lee RF, Steinert S, 2003. Use of the single cell gel electrophoresis/ comet assay for detecting DNA damage in aquatic (marine and freshwater) animals. Mutat. Res. 544: 43-64.
56. Lewis C, Galloway T, 2009. Reproductive consequences of paternal genotoxin exposure in marine invertebrates. Environ. Sci. Technol. 43: 928-933.
57. Magni P, De Falco G, Falugi C, Franzoni M, Monteverde M et al., 2006. Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean). Environ. Pollut. 142: 65-72.
58. Malins DC, McCain BB, Landahl JT, Myers MS, Krahn MM, 1988. Neoplastic and others diseases in fish in relation to toxic chemicals: An overview. Aquat. Toxicol. 11: 43-67.
59. Malins DC, Ostrander GK, Haimanot R, Williams P, 1990. A novel DNA lesion in neoplastic livers of feral fish: 2,6-diamino- 4-hydroxy-5-formamidopyrimidine. Carcinogenesis 11: 1045-1047.
60. Mix MC, 1986. Cancerous disease in aquatic animals and their association with environmental pollutants: A critical literature review. Mar. Environ. Res. 20: 1-141.
61. Myers MS, Rhodes LD, McCain BB, 1987. Pathologic anatomy and patterns of occurrence of hepatic neoplasms, putative preneoplastic lesions, and other idiopathic hepatic conditions in English sole Parophrys vetulus from Puget Sound, Washington. J. Natl. Cancer Inst. 78: 333-363.
62. Myers MS, Johnson LL, Collier TK, 2003. Establishing the causal relationship between polycyclic aromatic hydrocarbon (PAH) exposure and hepatic neoplasms and neoplasia-related liver lesions in English sole Pleuronectes vetulus. Hum. Ecol. Risk. Assess. 9: 67-94.
63. Myers MS, Anulacion BF, French BL, Reichert WL, Laetz CA et al., 2008. Improved flatfish health following remediation of a PAH-contaminated site in Eagle Harbor, Washington. Aquat. Toxicol. 88: 277-288.
64. Nigro M, Fallen A, Del Barga I, Scarcelli V, Lucchesi P et al., 2006. Cellular biomarkers for monitoring estuarine environments: Transplanted versus native mussels. Aquat. Toxicol. 77: 339-347.
65. Oliveira M, Maria VL, Ahmad I, Pacheco M, Santos MA, 2010. Seasonal Liza aurata tissue-specific DNA integrity in a multi-contaminated coastal lagoon (Ria de Aveiro, Portugal). Mar. Pollut. Bull. 60:1755-1761.
66. Osterauer R, Faßbender C, Braunbeck T, Köhler HR, 2011. Genotoxicity of platinum in embryos of zebrafish Danio rerio and ramshorn snail Marisa cornuarietis. Sci. Total Environ. 409: 2114-2119.
67. Pampanin DM, Marangon I, Volpato E, Campesan G, Nasci C, 2005. Stress biomarkers and alkali-labile phosphate level in mussels Mytilus galloprovincialis collected in the urban area of Venice (Venice Lagoon, Italy). Environ. Pollut. 136: 103-107.
68. Pisanelli B, Benedetti M, Fattorini D, Regoli F, 2009. Seasonal and inter-annual variability of DNA integrity in mussels Mytilus galloprovincialis: A possible role for natural fluctuations of trace metal concentrations and oxidative larval biomarkers. Chemosphere 77:1551-1557.
69. Rank J, Jensen K, Jespersen PJ, 2005. Monitoring DNA damage in indigenous blue mussels Mytilus edulis sampled from coastal sites in Denmark. Mutat. Res. 585: 33-42.
70. Rank J, Lehtonen KK, Strand J, Laursen M, 2007. DNA damage, acetylcholinesterase activity and lysosomal stability in native and transplanted mussels Mytilus edulis in areas close to coastal chemical dumping sites in Denmark. Aquat. Toxicol. 84: 50-61.
71. Rank J, 2009. Intersex in Littorina littorea and DNA damage in Mytilus edulis as indicators of harbour pollution. Ecotoxicol. Environ. Saf. 72:1271-1277.
72. Regoli F, Frenzilli G, Bocchetti R, Annarumma F, Scarcelli V, 2004. Time-course variations of oxyradical metabolism, DNA integrity and lysosomal stability in mussels Mytilus galloprovincialis during a field translocation experiment Aquat. Toxicol. 68: 167-178.
73. Santos LHMLM, Araujo AN, Fachini A, Pena A, Deleure-Matos C et al., 2010. Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment. J. Hazard Mat. 175: 45-95.
74. Sarkar A, Gaitonde DC, Sarkar A, Vashistha D, D'Silva C et al., 2008. Evaluation of impairment of DNA integrity in marine gastropods Cronia contracta as a biomarker of genotoxic contaminants in coastal water around Goa, West coast of India. Ecotoxicol. Environ. Saf. 71:473-82.
75. Schiedek D, Broeg K, Barsiene J, Lehtonen KK, Gercken J et al., 2006. Biomarker responses as indication of contaminant effects in blue mussel Mytilus edulis and female eelpout Zoarces viviparous from the southwestern Baltic Sea. Mar. Pollut. Bull. 53: 387-405.
76. Shaw JP, Large AT, Donkin P, Evans SV, Staff FJ et al., 2004. Seasonal variation in cytochrome P450 immunopositive protein levels, lipid peroxidation and genetic toxicity in digestive gland of the mussel Mytilus edulis. Aquatic Toxicol. 67: 325-336.
77. Soares-da-Silva IM, Ribeiro J, Valongo C, Pinto B, Vilanova M et al., 2002. Cytometric, morphologic and enzymatic characterisation of haemocytes in Anodonta cygnea. Comp. Biochem. Physiol. A. 132: 541-553.
78. Stein JE, Collier TK, Reichert WL, 1992. Bioindicators of contaminant exposure and sublethal effects: Studies with benthic fish in Puget sound, Washington. Environ. Toxicol. Chem. 11: 701-714.
79. Steinert SA, Streib-Montee R, Leather JM, Chadwick DB, 1998. DNA damage in mussels at sites in San Diego Bay. Mutat. Res. 399: 65-85.
80. Taban IC, Bechmann RK, Torgrimsen S, Baussant T, Sanni S, 2004. Detection of DNA damage in mussels and sea urchins exposed to crude oil using comet assay Mar. Environ. Res. 58: 701-705.
81. Venier P, Canova S, 1996. Formation of DNA adducts in the gill tissue of Mytilus galloprovincialis treated with benzo[a]pyrene. Aquat.Toxicol. 34: 119-133.
82. Venier P, Zampieron C, 2005. Evidence of genetic damage in grass gobies and mussels from the Venice lagoon. Environ. Int. 31: 1053-1064.
83. Viarengo A, Lowe D, Bolognesi C, Fabbri E, Koehler A, 2007. The use of biomarkers in biomonitoring: A 2-tier approach assessing the level of pollutant-induced stress syndrome in sentinel organisms. Comp. Biochem. Phys. Part C 146: 281-300.
84. Vincent-Hubert F, Revel M, Garric J, 2012. DNA strand breaks detected in embryos of the adult snails Potamopyrgus antipodarum, and in neonates exposed to genotoxic chemicals. Aquat. Toxicol. 122/123: 1-8.
85. Vorosmarty CJ, McIntyre PB, Gessner MO, Dudgeon D, Prusevich A et al., 2010 Global threats to human water security and river biodiversity. Nature 468: 334.