메뉴 건너뛰기




Volumn 11, Issue 6, 2013, Pages 606-620

Pharmacological inhibition of voltage-gated Ca2+ channels for chronic pain relief

Author keywords

Inhibition; L type Ca2+ channels; N type Ca2+ channels; Pain; T type Ca2+ channels; Targeting; Voltage gated Ca2+ channels; 2 subunit

Indexed keywords

AMPA RECEPTOR; ANALGESIC AGENT; BENZOTHIAZEPINE DERIVATIVE; BUTYLCAINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM CHANNEL R TYPE; CALCIUM CHANNEL T TYPE; CAPSAICIN; CYSTEINE; DIHYDROPYRIDINE; DILTIAZEM; GABAPENTIN; GLYCOSYLPHOSPHATIDYLINOSITOL; GRAMICIDIN; LIDOCAINE ETHOBROMIDE; NEUROTOXIN; NIFEDIPINE; OMEGA CONOTOXIN MVIIA; PHENYLALKYLAMINE; POTASSIUM CHANNEL; PREGABALIN; TRAZODONE; UNINDEXED DRUG; VOLTAGE GATED CALCIUM CHANNEL; ZONISAMIDE;

EID: 84899126267     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/1570159X11311060005     Document Type: Article
Times cited : (78)

References (173)
  • 1
    • 34547184022 scopus 로고    scopus 로고
    • Nociceptors--noxious stimulus detectors
    • Woolf, C.J.; Ma, Q. Nociceptors--noxious stimulus detectors. Neuron, 2007, 55(3), 353-364.
    • (2007) Neuron , vol.55 , Issue.3 , pp. 353-364
    • Woolf, C.J.1    Ma, Q.2
  • 2
    • 0037741037 scopus 로고    scopus 로고
    • Calcium signaling in single peripheral sensory nerve terminals
    • Gover, T.D.; Kao, J.P.; Weinreich, D. Calcium signaling in single peripheral sensory nerve terminals. J. Neurosci., 2003, 23(12), 4793-4797.
    • (2003) J. Neurosci. , vol.23 , Issue.12 , pp. 4793-4797
    • Gover, T.D.1    Kao, J.P.2    Weinreich, D.3
  • 3
    • 67651048942 scopus 로고    scopus 로고
    • Neuropathic pain: A maladaptive response of the nervous system to damage
    • Costigan, M.; Scholz, J.; Woolf, C.J. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu. Rev. Neurosci., 2009, 32, 1-32.
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 1-32
    • Costigan, M.1    Scholz, J.2    Woolf, C.J.3
  • 4
    • 78149361540 scopus 로고    scopus 로고
    • Overcoming obstacles to developing new analgesics
    • Woolf, C.J. Overcoming obstacles to developing new analgesics. Nat. Med., 2010, 16(11), 1241-1247.
    • (2010) Nat. Med. , vol.16 , Issue.11 , pp. 1241-1247
    • Woolf, C.J.1
  • 6
    • 52049098700 scopus 로고    scopus 로고
    • Calcium channel regulation and presynaptic plasticity
    • Catterall, W.A.; Few, A.P. Calcium channel regulation and presynaptic plasticity. Neuron, 2008, 59(6), 882-901.
    • (2008) Neuron , vol.59 , Issue.6 , pp. 882-901
    • Catterall, W.A.1    Few, A.P.2
  • 7
    • 80051776262 scopus 로고    scopus 로고
    • Targeting voltage-gated calcium channels for the treatment of neuropathic pain: A review of drug development
    • Pexton, T.; Moeller-Bertram, T.; Schilling, J.M.; Wallace, M.S. Targeting voltage-gated calcium channels for the treatment of neuropathic pain: a review of drug development. Expert. Opin. Investig. Drugs, 2011, 20(9), 1277-1284.
    • (2011) Expert. Opin. Investig. Drugs , vol.20 , Issue.9 , pp. 1277-1284
    • Pexton, T.1    Moeller-Bertram, T.2    Schilling, J.M.3    Wallace, M.S.4
  • 9
    • 29844439240 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels
    • Catterall, W.A.; Perez-Reyes, E.; Snutch, T.P.; Striessnig, J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol. Rev., 2005, 57(4), 411-425.
    • (2005) Pharmacol. Rev. , vol.57 , Issue.4 , pp. 411-425
    • Catterall, W.A.1    Perez-Reyes, E.2    Snutch, T.P.3    Striessnig, J.4
  • 10
    • 84864153599 scopus 로고    scopus 로고
    • Calcium channel auxiliary alpha2delta and beta subunits: Trafficking and one step beyond
    • Dolphin, A.C. Calcium channel auxiliary alpha2delta and beta subunits: trafficking and one step beyond. Nat. Rev. Neurosci., 2012, 13(8), 542-555.
    • (2012) Nat. Rev. Neurosci. , vol.13 , Issue.8 , pp. 542-555
    • Dolphin, A.C.1
  • 12
    • 0033134819 scopus 로고    scopus 로고
    • Absence of modulation of the expressed calcium channel alpha1G subunit by alpha2delta subunits
    • Pt 3
    • Lacinova, L.; Klugbauer, N.; Hofmann, F. Absence of modulation of the expressed calcium channel alpha1G subunit by alpha2delta subunits. J. Physiol., 1999, 516 (Pt 3), 639-645.
    • (1999) J. Physiol. , vol.516 , pp. 639-645
    • Lacinova, L.1    Klugbauer, N.2    Hofmann, F.3
  • 14
    • 84876893493 scopus 로고    scopus 로고
    • Alternative splicing: Functional diversity among voltage-gated calcium channels and behavioral consequences
    • Lipscombe, D.; Andrade, A.; Allen, S.E. Alternative splicing: Functional diversity among voltage-gated calcium channels and behavioral consequences. Biochim. Biophys. Acta, 2012.
    • (2012) Biochim. Biophys. Acta
    • Lipscombe, D.1    Andrade, A.2    Allen, S.E.3
  • 15
    • 53049084873 scopus 로고    scopus 로고
    • Alternative splicing matters: N-type calcium channels in nociceptors
    • Lipscombe, D.; Raingo, J. Alternative splicing matters: N-type calcium channels in nociceptors. Channels (Austin), 2007, 1(4), 225-227.
    • (2007) Channels (Austin) , vol.1 , Issue.4 , pp. 225-227
    • Lipscombe, D.1    Raingo, J.2
  • 18
    • 0347224274 scopus 로고    scopus 로고
    • Cell-specific alternative splicing increases calcium channel current density in the pain pathway
    • Bell, T.J.; Thaler, C.; Castiglioni, A.J.; Helton, T.D.; Lipscombe, D. Cell-specific alternative splicing increases calcium channel current density in the pain pathway. Neuron, 2004, 41(1), 127-138.
    • (2004) Neuron , vol.41 , Issue.1 , pp. 127-138
    • Bell, T.J.1    Thaler, C.2    Castiglioni, A.J.3    Helton, T.D.4    Lipscombe, D.5
  • 19
    • 33847198227 scopus 로고    scopus 로고
    • Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors
    • Raingo, J.; Castiglioni, A.J.; Lipscombe, D. Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors. Nat. Neurosci., 2007, 10(3), 285-292.
    • (2007) Nat. Neurosci. , vol.10 , Issue.3 , pp. 285-292
    • Raingo, J.1    Castiglioni, A.J.2    Lipscombe, D.3
  • 21
    • 34248995257 scopus 로고    scopus 로고
    • The action potential in mammalian central neurons
    • Bean, B.P. The action potential in mammalian central neurons. Nat. Rev. Neurosci., 2007, 8(6), 451-465.
    • (2007) Nat. Rev. Neurosci. , vol.8 , Issue.6 , pp. 451-465
    • Bean, B.P.1
  • 22
    • 27744563691 scopus 로고    scopus 로고
    • Neuronal L-type calcium channels open quickly and are inhibited slowly
    • Helton, T.D.; Xu, W.; Lipscombe, D. Neuronal L-type calcium channels open quickly and are inhibited slowly. J. Neurosci., 2005, 25(44), 10247-10251.
    • (2005) J. Neurosci. , vol.25 , Issue.44 , pp. 10247-10251
    • Helton, T.D.1    Xu, W.2    Lipscombe, D.3
  • 25
    • 0026502169 scopus 로고
    • Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size
    • Scroggs, R.S.; Fox, A.P. Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size. J Physiol., 1992, 445, 639-658.
    • (1992) J Physiol , vol.445 , pp. 639-658
    • Scroggs, R.S.1    Fox, A.P.2
  • 26
    • 0035964777 scopus 로고    scopus 로고
    • Expression of voltage-gated calcium channel subunits in rat dorsal root ganglion neurons
    • Yusaf, S.P.; Goodman, J.; Pinnock, R.D.; Dixon, A.K.; Lee, K. Expression of voltage-gated calcium channel subunits in rat dorsal root ganglion neurons. Neurosci. Lett., 2001, 311(2), 137-141.
    • (2001) Neurosci. Lett. , vol.311 , Issue.2 , pp. 137-141
    • Yusaf, S.P.1    Goodman, J.2    Pinnock, R.D.3    Dixon, A.K.4    Lee, K.5
  • 27
    • 0032528631 scopus 로고    scopus 로고
    • 2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals
    • 2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals. J. Neurosci., 1998, 18(16), 6319-6330.
    • (1998) J. Neurosci. , vol.18 , Issue.16 , pp. 6319-6330
    • Westenbroek, R.E.1    Hoskins, L.2    Catterall, W.A.3
  • 28
    • 0025128857 scopus 로고
    • Low-and high-voltage-activated calcium currents in rat spinal dorsal horn neurons
    • Ryu, P.D.; Randic, M. Low-and high-voltage-activated calcium currents in rat spinal dorsal horn neurons. J. Neurophysiol., 1990, 63(2), 273-285.
    • (1990) J. Neurophysiol. , vol.63 , Issue.2 , pp. 273-285
    • Ryu, P.D.1    Randic, M.2
  • 29
    • 1642580583 scopus 로고    scopus 로고
    • 2+ channels to nociceptive transmission in rat spinal lamina I neurons
    • 2+ channels to nociceptive transmission in rat spinal lamina I neurons. Eur. J. Neurosci., 2004, 19(1), 103-111.
    • (2004) Eur. J. Neurosci. , vol.19 , Issue.1 , pp. 103-111
    • Heinke, B.1    Balzer, E.2    Sandkuhler, J.3
  • 30
    • 30844473761 scopus 로고    scopus 로고
    • Calcium channels as therapeutic targets in neuropathic pain
    • Yaksh, T.L. Calcium channels as therapeutic targets in neuropathic pain. J. Pain, 2006, 7(1 Suppl 1), S13-30.
    • (2006) J. Pain , vol.7 , Issue.1 , pp. S13-S30
    • Yaksh, T.L.1
  • 31
    • 78650829206 scopus 로고    scopus 로고
    • Calcium channel functions in pain processing
    • Park, J.; Luo, Z.D. Calcium channel functions in pain processing. Channels (Austin), 2010, 4(6), 510-517.
    • (2010) Channels (Austin) , vol.4 , Issue.6 , pp. 510-517
    • Park, J.1    Luo, Z.D.2
  • 33
    • 21844438495 scopus 로고    scopus 로고
    • Distribution and regulation of L-type calcium channels in deep dorsal horn neurons after sciatic nerve injury in rats
    • Dobremez, E.; Bouali-Benazzouz, R.; Fossat, P.; Monteils, L.; Dulluc, J.; Nagy, F.; Landry, M. Distribution and regulation of L-type calcium channels in deep dorsal horn neurons after sciatic nerve injury in rats. Eur. J. Neurosci., 2005, 21(12), 3321-3333.
    • (2005) Eur. J. Neurosci. , vol.21 , Issue.12 , pp. 3321-3333
    • Dobremez, E.1    Bouali-Benazzouz, R.2    Fossat, P.3    Monteils, L.4    Dulluc, J.5    Nagy, F.6    Landry, M.7
  • 34
    • 60349106780 scopus 로고    scopus 로고
    • (V)1.3 immunoreactivity in the rat spinal cord and brain stem
    • (V)1.3 immunoreactivity in the rat spinal cord and brain stem. Neuroscience, 2009, 159(1), 217-235.
    • (2009) Neuroscience , vol.159 , Issue.1 , pp. 217-235
    • Sukiasyan, N.1    Hultborn, H.2    Zhang, M.3
  • 35
    • 0035976724 scopus 로고    scopus 로고
    • Changes in voltage-gated calcium channel alpha(1) gene expression in rat dorsal root ganglia following peripheral nerve injury
    • Kim, D.S.; Yoon, C.H.; Lee, S.J.; Park, S.Y.; Yoo, H.J.; Cho, H.J. Changes in voltage-gated calcium channel alpha(1) gene expression in rat dorsal root ganglia following peripheral nerve injury. Brain Res. Mol. Brain Res., 2001, 96(1-2), 151-156.
    • (2001) Brain Res. Mol. Brain Res. , vol.96 , Issue.1-2 , pp. 151-156
    • Kim, D.S.1    Yoon, C.H.2    Lee, S.J.3    Park, S.Y.4    Yoo, H.J.5    Cho, H.J.6
  • 41
    • 84861187410 scopus 로고    scopus 로고
    • V2.1 voltage activated calcium channels and synaptic transmission in familial hemiplegic migraine pathogenesis
    • V2.1 voltage activated calcium channels and synaptic transmission in familial hemiplegic migraine pathogenesis. J. Physiol. Paris, 2012, 106(1-2), 12-22.
    • (2012) J. Physiol. Paris , vol.106 , Issue.1-2 , pp. 12-22
    • Uchitel, O.D.1    Inchauspe, C.G.2    Urbano, F.J.3    Di Guilmi, M.N.4
  • 42
    • 0030964099 scopus 로고    scopus 로고
    • Either N-or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses
    • Poncer, J.C.; McKinney, R.A.; Gahwiler, B.H.; Thompson, S.M. Either N-or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses. Neuron, 1997, 18(3), 463-472.
    • (1997) Neuron , vol.18 , Issue.3 , pp. 463-472
    • Poncer, J.C.1    McKinney, R.A.2    Gahwiler, B.H.3    Thompson, S.M.4
  • 43
    • 0029865382 scopus 로고    scopus 로고
    • Differential regulation of evoked peptide release by voltage-sensitive calcium channels in rat sensory neurons
    • Evans, A.R.; Nicol, G.D.; Vasko, M.R. Differential regulation of evoked peptide release by voltage-sensitive calcium channels in rat sensory neurons. Brain Res., 1996, 712(2), 265-273.
    • (1996) Brain Res , vol.712 , Issue.2 , pp. 265-273
    • Evans, A.R.1    Nicol, G.D.2    Vasko, M.R.3
  • 44
    • 79851509083 scopus 로고    scopus 로고
    • Role of voltage-dependent calcium channel subtypes in spinal long-term potentiation of C-fiber-evoked field potentials
    • Ohnami, S.; Tanabe, M.; Shinohara, S.; Takasu, K.; Kato, A.; Ono, H. Role of voltage-dependent calcium channel subtypes in spinal long-term potentiation of C-fiber-evoked field potentials. Pain, 2011, 152(3), 623-631.
    • (2011) Pain , vol.152 , Issue.3 , pp. 623-631
    • Ohnami, S.1    Tanabe, M.2    Shinohara, S.3    Takasu, K.4    Kato, A.5    Ono, H.6
  • 45
    • 0035059152 scopus 로고    scopus 로고
    • Effects of spinally delivered N-and P-type voltage-dependent calcium channel antagonists on dorsal horn neuronal responses in a rat model of neuropathy
    • Matthews, E.A.; Dickenson, A.H. Effects of spinally delivered N-and P-type voltage-dependent calcium channel antagonists on dorsal horn neuronal responses in a rat model of neuropathy. Pain, 2001, 92(1-2), 235-246.
    • (2001) Pain , vol.92 , Issue.1-2 , pp. 235-246
    • Matthews, E.A.1    Dickenson, A.H.2
  • 46
    • 0028335910 scopus 로고
    • Role of voltage-dependent calcium channel subtypes in experimental tactile allodynia
    • Chaplan, S.R.; Pogrel, J.W.; Yaksh, T.L. Role of voltage-dependent calcium channel subtypes in experimental tactile allodynia. J. Pharmacol. Exp. Ther., 1994, 269(3), 1117-1123.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , Issue.3 , pp. 1117-1123
    • Chaplan, S.R.1    Pogrel, J.W.2    Yaksh, T.L.3
  • 47
    • 0032103141 scopus 로고    scopus 로고
    • Differential effects of intrathecally administered N-and P-type voltage-sensitive calcium channel blockers upon two models of experimental mononeuropathy in the rat
    • Yamamoto, T.; Sakashita, Y. Differential effects of intrathecally administered N-and P-type voltage-sensitive calcium channel blockers upon two models of experimental mononeuropathy in the rat. Brain Res., 1998, 794(2), 329-332.
    • (1998) Brain Res , vol.794 , Issue.2 , pp. 329-332
    • Yamamoto, T.1    Sakashita, Y.2
  • 51
    • 0027050486 scopus 로고
    • Biochemical properties and subcellular distribution of an N-type calcium channel alpha 1 subunit
    • Westenbroek, R.E.; Hell, J.W.; Warner, C.; Dubel, S.J.; Snutch, T.P.; Catterall, W.A. Biochemical properties and subcellular distribution of an N-type calcium channel alpha 1 subunit. Neuron, 1992, 9(6), 1099-1115.
    • (1992) Neuron , vol.9 , Issue.6 , pp. 1099-1115
    • Westenbroek, R.E.1    Hell, J.W.2    Warner, C.3    Dubel, S.J.4    Snutch, T.P.5    Catterall, W.A.6
  • 52
    • 0026596064 scopus 로고
    • Release of calcitonin gene-related peptide like-immunoreactivity induced by electrical field stimulation from rat spinal afferents is mediated by conotoxin-sensitive calcium channels
    • Santicioli, P.; Del Bianco, E.; Tramontana, M.; Geppetti, P.; Maggi, C.A. Release of calcitonin gene-related peptide like-immunoreactivity induced by electrical field stimulation from rat spinal afferents is mediated by conotoxin-sensitive calcium channels. Neurosci. Lett., 1992, 136(2), 161-164.
    • (1992) Neurosci. Lett. , vol.136 , Issue.2 , pp. 161-164
    • Santicioli, P.1    Del Bianco, E.2    Tramontana, M.3    Geppetti, P.4    Maggi, C.A.5
  • 53
    • 0028428318 scopus 로고
    • Omega-conotoxin sensitivity and presynaptic inhibition of glutamatergic sensory neurotransmission in vitro
    • Gruner, W.; Silva, L.R. Omega-conotoxin sensitivity and presynaptic inhibition of glutamatergic sensory neurotransmission in vitro. J. Neurosci., 1994, 14(5 Pt 1), 2800-2808.
    • (1994) J. Neurosci. , vol.14 , Issue.5 , pp. 2800-2808
    • Gruner, W.1    Silva, L.R.2
  • 54
    • 0023851275 scopus 로고
    • Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: Methods and dihydropyridine sensitivity
    • Holz, G.G.t.; Dunlap, K.; Kream, R.M. Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity. J. Neurosci., 1988, 8(2), 463-471.
    • (1988) J. Neurosci. , vol.8 , Issue.2 , pp. 463-471
    • Holz, G.G.T.1    Dunlap, K.2    Kream, R.M.3
  • 55
    • 0023879251 scopus 로고
    • Autoradiographic localization of calcium channels with [125I]omega-conotoxin in rat brain
    • Kerr, L.M.; Filloux, F.; Olivera, B.M.; Jackson, H.; Wamsley, J.K. Autoradiographic localization of calcium channels with [125I]omega-conotoxin in rat brain. Eur. J. Pharmacol., 1988, 146(1), 181-183.
    • (1988) Eur. J. Pharmacol. , vol.146 , Issue.1 , pp. 181-183
    • Kerr, L.M.1    Filloux, F.2    Olivera, B.M.3    Jackson, H.4    Wamsley, J.K.5
  • 56
    • 0028105906 scopus 로고
    • Neuro-anatomical distribution of receptors for a novel voltage-sensitive calcium-channel antagonist, SNX-230 (Omega-conopeptide MVIIC)
    • Gohil, K.; Bell, J.R.; Ramachandran, J.; Miljanich, G.P. Neuro-anatomical distribution of receptors for a novel voltage-sensitive calcium-channel antagonist, SNX-230 (omega-conopeptide MVIIC). Brain Res., 1994, 653(1-2), 258-266.
    • (1994) Brain Res. , vol.653 , Issue.1-2 , pp. 258-266
    • Gohil, K.1    Bell, J.R.2    Ramachandran, J.3    Miljanich, G.P.4
  • 57
    • 0026612746 scopus 로고
    • Multiple Ca2+ currents elicited by action potential waveforms in acutely isolated adult rat dorsal root ganglion neurons
    • Scroggs, R.S.; Fox, A.P. Multiple Ca2+ currents elicited by action potential waveforms in acutely isolated adult rat dorsal root ganglion neurons. J. Neurosci., 1992, 12(5), 1789-1801.
    • (1992) J. Neurosci. , vol.12 , Issue.5 , pp. 1789-1801
    • Scroggs, R.S.1    Fox, A.P.2
  • 58
    • 78049469780 scopus 로고    scopus 로고
    • Persistent inflammation alters the density and distribution of voltage-activated calcium channels in subpopulations of rat cutaneous DRG neurons
    • Lu, S.G.; Zhang, X.L.; Luo, Z.D.; Gold, M.S. Persistent inflammation alters the density and distribution of voltage-activated calcium channels in subpopulations of rat cutaneous DRG neurons. Pain, 2010, 151(3), 633-643.
    • (2010) Pain , vol.151 , Issue.3 , pp. 633-643
    • Lu, S.G.1    Zhang, X.L.2    Luo, Z.D.3    Gold, M.S.4
  • 60
    • 0035869568 scopus 로고    scopus 로고
    • Upregulation of dorsal root ganglion (Alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats
    • Luo, Z.D.; Chaplan, S.R.; Higuera, E.S.; Sorkin, L.S.; Stauderman, K.A.; Williams, M.E.; Yaksh, T.L. Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. J. Neurosci., 2001, 21(6), 1868-1875.
    • (2001) J. Neurosci. , vol.21 , Issue.6 , pp. 1868-1875
    • Luo, Z.D.1    Chaplan, S.R.2    Higuera, E.S.3    Sorkin, L.S.4    Stauderman, K.A.5    Williams, M.E.6    Yaksh, T.L.7
  • 61
    • 34249862424 scopus 로고    scopus 로고
    • Inflammation reduces the contribution of N-type calcium channels to primary afferent synaptic transmission onto NK1 receptor-positive lamina I neurons in the rat dorsal horn
    • Rycroft, B.K.; Vikman, K.S.; Christie, M.J. Inflammation reduces the contribution of N-type calcium channels to primary afferent synaptic transmission onto NK1 receptor-positive lamina I neurons in the rat dorsal horn. J. Physiol., 2007, 580(Pt.3), 883-894.
    • (2007) J. Physiol. , vol.580 , pp. 883-894
    • Rycroft, B.K.1    Vikman, K.S.2    Christie, M.J.3
  • 66
    • 0030956879 scopus 로고    scopus 로고
    • Blockade of calcium channels can prevent the onset of secondary hyperalgesia and allodynia induced by intradermal injection of capsaicin in rats
    • Sluka, K.A. Blockade of calcium channels can prevent the onset of secondary hyperalgesia and allodynia induced by intradermal injection of capsaicin in rats. Pain, 1997, 71(2), 157-164.
    • (1997) Pain , vol.71 , Issue.2 , pp. 157-164
    • Sluka, K.A.1
  • 67
    • 0032454062 scopus 로고    scopus 로고
    • Blockade of N-and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation
    • Sluka, K.A. Blockade of N-and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation. J Pharmacol. Exp. Ther., 1998, 287(1), 232-237.
    • (1998) J Pharmacol. Exp. Ther. , vol.287 , Issue.1 , pp. 232-237
    • Sluka, K.A.1
  • 68
    • 34249017949 scopus 로고    scopus 로고
    • Ziconotide: A review of its pharmacology and use in the treatment of pain
    • McGivern, J.G. Ziconotide: a review of its pharmacology and use in the treatment of pain. Neuropsychiatr. Dis. Treat, 2007, 3(1), 69-85.
    • (2007) Neuropsychiatr. Dis. Treat , vol.3 , Issue.1 , pp. 69-85
    • McGivern, J.G.1
  • 69
    • 0037144134 scopus 로고    scopus 로고
    • Actions of intrathecal omega-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat
    • Scott, D.A.; Wright, C.E.; Angus, J.A. Actions of intrathecal omega-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat. Eur. J. Pharmacol., 2002, 451(3), 279-286.
    • (2002) Eur. J. Pharmacol. , vol.451 , Issue.3 , pp. 279-286
    • Scott, D.A.1    Wright, C.E.2    Angus, J.A.3
  • 72
    • 34347389926 scopus 로고    scopus 로고
    • v2.3 calcium channel antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of chronic neuropathic pain
    • v2.3 calcium channel antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of chronic neuropathic pain. Eur. J. Neurosci., 2007, 25(12), 3561-3569.
    • (2007) Eur. J. Neurosci. , vol.25 , Issue.12 , pp. 3561-3569
    • Matthews, E.A.1    Bee, L.A.2    Stephens, G.J.3    Dickenson, A.H.4
  • 73
    • 4644350854 scopus 로고    scopus 로고
    • Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice
    • Murakami, M.; Nakagawasai, O.; Suzuki, T.; Mobarakeh, II; Sakurada, Y.; Murata, A.; Yamadera, F.; Miyoshi, I.; Yanai, K.; Tan-No, K.; Sasano, H.; Tadano, T.; Iijima, T. Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice. Brain Res., 2004, 1024(1-2), 122-129.
    • (2004) Brain Res , vol.1024 , Issue.1-2 , pp. 122-129
    • Murakami, M.1    Nakagawasai, O.2    Suzuki, T.3    Mobarakeh, I.I.4    Sakurada, Y.5    Murata, A.6    Yamadera, F.7    Miyoshi, I.8    Yanai, K.9    Tan-No, K.10    Sasano, H.11    Tadano, T.12    Iijima, T.13
  • 74
    • 70349989966 scopus 로고    scopus 로고
    • Effects of neuropathy on high-voltage-activated Ca(2+) current in sensory neurones
    • Yang, L.; Stephens, G.J. Effects of neuropathy on high-voltage-activated Ca(2+) current in sensory neurones. Cell Calcium, 2009, 46(4), 248-256.
    • (2009) Cell Calcium , vol.46 , Issue.4 , pp. 248-256
    • Yang, L.1    Stephens, G.J.2
  • 77
    • 84863494346 scopus 로고    scopus 로고
    • v3.2 channels regulate excitatory neurotransmission in nociceptive dorsal horn neurons
    • v3.2 channels regulate excitatory neurotransmission in nociceptive dorsal horn neurons. J. Neurosci., 2012, 32(27), 9374-9382.
    • (2012) J. Neurosci. , vol.32 , Issue.27 , pp. 9374-9382
    • Jacus, M.O.1    Uebele, V.N.2    Renger, J.J.3    Todorovic, S.M.4
  • 78
    • 84876926362 scopus 로고    scopus 로고
    • Control of low-threshold exocytosis by T-type calcium channels
    • Weiss, N.; Zamponi, G.W. Control of low-threshold exocytosis by T-type calcium channels. Biochim. Biophys. Acta, 2012, 1828 (7), 1579-86.
    • (2012) Biochim. Biophys. Acta , vol.1828 , Issue.7 , pp. 1579-1586
    • Weiss, N.1    Zamponi, G.W.2
  • 79
    • 0037458899 scopus 로고    scopus 로고
    • Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia
    • Ikeda, H.; Heinke, B.; Ruscheweyh, R.; Sandkuhler, J. Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia. Science, 2003, 299(5610), 1237-1240.
    • (2003) Science , vol.299 , Issue.5610 , pp. 1237-1240
    • Ikeda, H.1    Heinke, B.2    Ruscheweyh, R.3    Sandkuhler, J.4
  • 80
    • 0034194621 scopus 로고    scopus 로고
    • Painful neuropathy decreases membrane calcium current in mammalian primary afferent neurons
    • Hogan, Q.H.; McCallum, J.B.; Sarantopoulos, C.; Aason, M.; Mynlieff, M.; Kwok, W.M.; Bosnjak, Z.J. Painful neuropathy decreases membrane calcium current in mammalian primary afferent neurons. Pain, 2000, 86(1-2), 43-53.
    • (2000) Pain , vol.86 , Issue.1-2 , pp. 43-53
    • Hogan, Q.H.1    McCallum, J.B.2    Sarantopoulos, C.3    Aason, M.4    Mynlieff, M.5    Kwok, W.M.6    Bosnjak, Z.J.7
  • 81
    • 0037217589 scopus 로고    scopus 로고
    • Loss of T-type calcium current in sensory neurons of rats with neuropathic pain
    • McCallum, J.B.; Kwok, W.M.; Mynlieff, M.; Bosnjak, Z.J.; Hogan, Q.H. Loss of T-type calcium current in sensory neurons of rats with neuropathic pain. Anesthesiology, 2003, 98(1), 209-216.
    • (2003) Anesthesiology , vol.98 , Issue.1 , pp. 209-216
    • McCallum, J.B.1    Kwok, W.M.2    Mynlieff, M.3    Bosnjak, Z.J.4    Hogan, Q.H.5
  • 83
    • 77951964265 scopus 로고    scopus 로고
    • The roles of T-type calcium channel in the development of neuropathic pain following chronic compression of rat dorsal root ganglia
    • Wen, X.J.; Xu, S.Y.; Chen, Z.X.; Yang, C.X.; Liang, H.; Li, H. The roles of T-type calcium channel in the development of neuropathic pain following chronic compression of rat dorsal root ganglia. Pharmacology, 2010, 85(5), 295-300.
    • (2010) Pharmacology , vol.85 , Issue.5 , pp. 295-300
    • Wen, X.J.1    Xu, S.Y.2    Chen, Z.X.3    Yang, C.X.4    Liang, H.5    Li, H.6
  • 84
    • 0037743562 scopus 로고    scopus 로고
    • A T-type calcium channel required for normal function of a mammalian mechanoreceptor
    • Shin, J.B.; Martinez-Salgado, C.; Heppenstall, P.A.; Lewin, G.R. A T-type calcium channel required for normal function of a mammalian mechanoreceptor. Nat. Neurosci., 2003, 6(7), 724-730.
    • (2003) Nat. Neurosci. , vol.6 , Issue.7 , pp. 724-730
    • Shin, J.B.1    Martinez-Salgado, C.2    Heppenstall, P.A.3    Lewin, G.R.4
  • 88
    • 33751366133 scopus 로고    scopus 로고
    • v3.3 antisense oligonucleotide reverses tactile allodynia and thermal hyperalgesia in rats following chronic compression of dorsal root of ganglion
    • v3.3 antisense oligonucleotide reverses tactile allodynia and thermal hyperalgesia in rats following chronic compression of dorsal root of ganglion. Acta Pharmacol. Sin., 2006, 27(12), 1547-1552.
    • (2006) Acta Pharmacol. Sin. , vol.27 , Issue.12 , pp. 1547-1552
    • Wen, X.J.1    Li, Z.J.2    Chen, Z.X.3    Fang, Z.Y.4    Yang, C.X.5    Li, H.6    Zeng, Y.M.7
  • 92
    • 84861947988 scopus 로고    scopus 로고
    • A. Alpha2delta expression sets presynaptic calcium channel abundance and release probability
    • Hoppa, M.B.; Lana, B.; Margas, W.; Dolphin, A.C.; Ryan, T.A. alpha2delta expression sets presynaptic calcium channel abundance and release probability. Nature, 2012, 486(7401), 122-125.
    • (2012) Nature , vol.486 , Issue.7401 , pp. 122-125
    • Hoppa, M.B.1    Lana, B.2    Margas, W.3    Dolphin, A.C.4    Ryan, T.5
  • 93
    • 0031808563 scopus 로고    scopus 로고
    • 2+ channel II: Activation and inactivation by physiological patterns of activity
    • 2+ channel II: activation and inactivation by physiological patterns of activity. Neuropharmacology, 1998, 37(1), 67-81.
    • (1998) Neuropharmacology , vol.37 , Issue.1 , pp. 67-81
    • McNaughton, N.C.1    Bleakman, D.2    Randall, A.D.3
  • 95
    • 77953235348 scopus 로고    scopus 로고
    • The anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo
    • Bauer, C.S.; Rahman, W.; Tran-van-Minh, A.; Lujan, R.; Dickenson, A.H.; Dolphin, A.C. The anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo. Biochem. Soc. Trans., 2010, 38(2), 525-528.
    • (2010) Biochem. Soc. Trans. , vol.38 , Issue.2 , pp. 525-528
    • Bauer, C.S.1    Rahman, W.2    Tran-Van-Minh, A.3    Lujan, R.4    Dickenson, A.H.5    Dolphin, A.C.6
  • 96
    • 0035500748 scopus 로고    scopus 로고
    • Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury
    • Newton, R.A.; Bingham, S.; Case, P.C.; Sanger, G.J.; Lawson, S.N. Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury. Brain Res. Mol. Brain Res., 2001, 95(1-2), 1-8.
    • (2001) Brain Res. Mol. Brain Res. , vol.95 , Issue.1-2 , pp. 1-8
    • Newton, R.A.1    Bingham, S.2    Case, P.C.3    Sanger, G.J.4    Lawson, S.N.5
  • 99
    • 0036155045 scopus 로고    scopus 로고
    • Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones
    • Sutton, K.G.; Martin, D.J.; Pinnock, R.D.; Lee, K.; Scott, R.H. Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones. Br. J. Pharmacol., 2002, 135(1), 257-265.
    • (2002) Br. J. Pharmacol. , vol.135 , Issue.1 , pp. 257-265
    • Sutton, K.G.1    Martin, D.J.2    Pinnock, R.D.3    Lee, K.4    Scott, R.H.5
  • 100
    • 0031809165 scopus 로고    scopus 로고
    • Gabapentin inhibits calcium currents in isolated rat brain neurons
    • Stefani, A.; Spadoni, F.; Bernardi, G. Gabapentin inhibits calcium currents in isolated rat brain neurons. Neuropharmacology, 1998, 37(1), 83-91.
    • (1998) Neuropharmacology , vol.37 , Issue.1 , pp. 83-91
    • Stefani, A.1    Spadoni, F.2    Bernardi, G.3
  • 102
    • 0035261666 scopus 로고    scopus 로고
    • Voltage-dependent calcium channels--beyond dihydropyridine antagonists
    • Snutch, T.P.; Sutton, K.G.; Zamponi, G.W. Voltage-dependent calcium channels--beyond dihydropyridine antagonists. Curr. Opin. Pharmacol., 2001, 1(1), 11-16.
    • (2001) Curr. Opin. Pharmacol. , vol.1 , Issue.1 , pp. 11-16
    • Snutch, T.P.1    Sutton, K.G.2    Zamponi, G.W.3
  • 103
    • 0020540118 scopus 로고
    • History of calcium antagonists
    • Fleckenstein, A. History of calcium antagonists. Circ. Res., 1983, 52(2 Pt 2), I3-16.
    • (1983) Circ. Res. , vol.52 , Issue.2 , pp. I3-I16
    • Fleckenstein, A.1
  • 104
    • 0030013986 scopus 로고    scopus 로고
    • The IVS6 segment of the L-type calcium channel is critical for the action of dihydropyridines and phenylalkylamines
    • Schuster, A.; Lacinova, L.; Klugbauer, N.; Ito, H.; Birnbaumer, L.; Hofmann, F. The IVS6 segment of the L-type calcium channel is critical for the action of dihydropyridines and phenylalkylamines. EMBO J, 1996, 15(10), 2365-2370.
    • (1996) EMBO J , vol.15 , Issue.10 , pp. 2365-2370
    • Schuster, A.1    Lacinova, L.2    Klugbauer, N.3    Ito, H.4    Birnbaumer, L.5    Hofmann, F.6
  • 107
    • 0025783595 scopus 로고
    • Block of L-type calcium channels by charged dihydropyridines. Sensitivity to side of application and calcium
    • Kass, R.S.; Arena, J.P.; Chin, S. Block of L-type calcium channels by charged dihydropyridines. Sensitivity to side of application and calcium. J. Gen. Physiol., 1991, 98(1), 63-75.
    • (1991) J. Gen. Physiol. , vol.98 , Issue.1 , pp. 63-75
    • Kass, R.S.1    Arena, J.P.2    Chin, S.3
  • 109
    • 0010452459 scopus 로고
    • Nitrendipine block of cardiac calcium channels: High-affinity binding to the inactivated state
    • Bean, B.P. Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state. Proc. Natl. Acad. Sci. U. S. A., 1984, 81(20), 6388-6392.
    • (1984) Proc. Natl. Acad. Sci. U. S. A. , vol.81 , Issue.20 , pp. 6388-6392
    • Bean, B.P.1
  • 110
    • 0033613178 scopus 로고    scopus 로고
    • Synthesis, bioactivity, and cloning of the L-type calcium channel blocker omega-conotoxin TxVII
    • Sasaki, T.; Feng, Z.P.; Scott, R.; Grigoriev, N.; Syed, N.I.; Fainzilber, M.; Sato, K. Synthesis, bioactivity, and cloning of the L-type calcium channel blocker omega-conotoxin TxVII. Biochemistry, 1999, 38(39), 12876-12884.
    • (1999) Biochemistry , vol.38 , Issue.39 , pp. 12876-12884
    • Sasaki, T.1    Feng, Z.P.2    Scott, R.3    Grigoriev, N.4    Syed, N.I.5    Fainzilber, M.6    Sato, K.7
  • 111
    • 0027941058 scopus 로고
    • Voltage-sensitive calcium channels in spinal nociceptive processing: Blockade of N-and P-type channels inhibits formalin-induced nociception
    • Malmberg, A.B.; Yaksh, T.L. Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N-and P-type channels inhibits formalin-induced nociception. J. Neurosci., 1994, 14(8), 4882-4890.
    • (1994) J. Neurosci. , vol.14 , Issue.8 , pp. 4882-4890
    • Malmberg, A.B.1    Yaksh, T.L.2
  • 112
    • 1842713310 scopus 로고    scopus 로고
    • Mechanical and thermal anti-nociception in rats after systemic administration of verapamil
    • Todorovic, S.M.; Pathirathna, S.; Meyenburg, A.; Jevtovic-Todorovic, V. Mechanical and thermal anti-nociception in rats after systemic administration of verapamil. Neurosci. Lett., 2004, 360(1-2), 57-60.
    • (2004) Neurosci. Lett. , vol.360 , Issue.1-2 , pp. 57-60
    • Todorovic, S.M.1    Pathirathna, S.2    Meyenburg, A.3    Jevtovic-Todorovic, V.4
  • 113
    • 0033550670 scopus 로고    scopus 로고
    • Pharmacological interaction of the calcium channel blockers verapamil and flunarizine with the opioid system
    • Weizman, R.; Getslev, V.; Pankova, I.A.; Schrieber, S.; Pick, C.G. Pharmacological interaction of the calcium channel blockers verapamil and flunarizine with the opioid system. Brain Res., 1999, 818(2), 187-195.
    • (1999) Brain Res , vol.818 , Issue.2 , pp. 187-195
    • Weizman, R.1    Getslev, V.2    Pankova, I.A.3    Schrieber, S.4    Pick, C.G.5
  • 114
    • 0028096838 scopus 로고
    • Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxin
    • Ellinor, P.T.; Zhang, J.F.; Horne, W.A.; Tsien, R.W. Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxin. Nature, 1994, 372(6503), 272-275.
    • (1994) Nature , vol.372 , Issue.6503 , pp. 272-275
    • Ellinor, P.T.1    Zhang, J.F.2    Horne, W.A.3    Tsien, R.W.4
  • 115
    • 0037490146 scopus 로고    scopus 로고
    • Determinants of inhibition of transiently expressed voltage-gated calcium channels by omega-conotoxins GVIA and MVIIA
    • Feng, Z.P.; Doering, C.J.; Winkfein, R.J.; Beedle, A.M.; Spafford, J.D.; Zamponi, G.W. Determinants of inhibition of transiently expressed voltage-gated calcium channels by omega-conotoxins GVIA and MVIIA. J. Biol. Chem., 2003, 278(22), 20171-20178.
    • (2003) J. Biol. Chem. , vol.278 , Issue.22 , pp. 20171-20178
    • Feng, Z.P.1    Doering, C.J.2    Winkfein, R.J.3    Beedle, A.M.4    Spafford, J.D.5    Zamponi, G.W.6
  • 116
    • 0033952153 scopus 로고    scopus 로고
    • Adverse effects associated with the intrathecal administration of ziconotide
    • Penn, R.D.; Paice, J.A. Adverse effects associated with the intrathecal administration of ziconotide. Pain, 2000, 85(1-2), 291-296.
    • (2000) Pain , vol.85 , Issue.1-2 , pp. 291-296
    • Penn, R.D.1    Paice, J.A.2
  • 117
    • 79959244402 scopus 로고    scopus 로고
    • Intravenous injection of leconotide, an omega conotoxin: Synergistic antihyperalgesic effects with morphine in a rat model of bone cancer pain
    • Kolosov, A.; Aurini, L.; Williams, E.D.; Cooke, I.; Goodchild, C.S. Intravenous injection of leconotide, an omega conotoxin: synergistic antihyperalgesic effects with morphine in a rat model of bone cancer pain. Pain Med., 2011, 12(6), 923-941.
    • (2011) Pain Med , vol.12 , Issue.6 , pp. 923-941
    • Kolosov, A.1    Aurini, L.2    Williams, E.D.3    Cooke, I.4    Goodchild, C.S.5
  • 118
    • 9744249496 scopus 로고    scopus 로고
    • Antinociceptive effects of intrathecally administered huwentoxin-I, a selective N-type calcium channel blocker, in the formalin test in conscious rats
    • Chen, J.Q.; Zhang, Y.Q.; Dai, J.; Luo, Z.M.; Liang, S.P. Antinociceptive effects of intrathecally administered huwentoxin-I, a selective N-type calcium channel blocker, in the formalin test in conscious rats. Toxicon, 2005, 45(1), 15-20.
    • (2005) Toxicon , vol.45 , Issue.1 , pp. 15-20
    • Chen, J.Q.1    Zhang, Y.Q.2    Dai, J.3    Luo, Z.M.4    Liang, S.P.5
  • 120
    • 66449104102 scopus 로고    scopus 로고
    • Recent updates of N-type calcium channel blockers with therapeutic potential for neuropathic pain and stroke
    • Yamamoto, T.; Takahara, A. Recent updates of N-type calcium channel blockers with therapeutic potential for neuropathic pain and stroke. Curr. Top Med. Chem., 2009, 9(4), 377-395.
    • (2009) Curr. Top Med. Chem. , vol.9 , Issue.4 , pp. 377-395
    • Yamamoto, T.1    Takahara, A.2
  • 126
    • 18544381669 scopus 로고    scopus 로고
    • L-Cysteine based N-type calcium channel blockers: Structure-activity relationships of the C-terminal lipophilic moiety, and oral analgesic efficacy in rat pain models
    • Seko, T.; Kato, M.; Kohno, H.; Ono, S.; Hashimura, K.; Takenobu, Y.; Takimizu, H.; Nakai, K.; Maegawa, H.; Katsube, N.; Toda, M. L-Cysteine based N-type calcium channel blockers: structure-activity relationships of the C-terminal lipophilic moiety, and oral analgesic efficacy in rat pain models. Bioorg. Med. Chem. Lett., 2002, 12(17), 2267-2269.
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , Issue.17 , pp. 2267-2269
    • Seko, T.1    Kato, M.2    Kohno, H.3    Ono, S.4    Hashimura, K.5    Takenobu, Y.6    Takimizu, H.7    Nakai, K.8    Maegawa, H.9    Katsube, N.10    Toda, M.11
  • 128
    • 0030695126 scopus 로고    scopus 로고
    • Diversity of calcium antagonists
    • Pitt, B. Diversity of calcium antagonists. Clin. Ther., 1997, 19 Suppl A, 3-17.
    • (1997) Clin. Ther. , vol.19 , pp. 3-17
    • Pitt, B.1
  • 129
    • 0028839687 scopus 로고
    • Effects of the new calcium antagonist mibefradil (Ro 40-5967) on exercise duration in patients with chronic stable angina pectoris: A multicenter, placebo-controlled study. Ro 40-5967 International Study Group
    • Bakx, A.L.; van der Wall, E.E.; Braun, S.; Emanuelsson, H.; Bruschke, A.V.; Kobrin, I. Effects of the new calcium antagonist mibefradil (Ro 40-5967) on exercise duration in patients with chronic stable angina pectoris: a multicenter, placebo-controlled study. Ro 40-5967 International Study Group. Am. Heart J., 1995, 130(4), 748-757.
    • (1995) Am. Heart J. , vol.130 , Issue.4 , pp. 748-757
    • Bakx, A.L.1    van der Wall, E.E.2    Braun, S.3    Emanuelsson, H.4    Bruschke, A.V.5    Kobrin, I.6
  • 131
    • 0037019860 scopus 로고    scopus 로고
    • Mechanical and thermal antinociception in rats following systemic administration of mibefradil, a T-type calcium channel blocker
    • Todorovic, S.M.; Meyenburg, A.; Jevtovic-Todorovic, V. Mechanical and thermal antinociception in rats following systemic administration of mibefradil, a T-type calcium channel blocker. Brain Res., 2002, 951(2), 336-340.
    • (2002) Brain Res , vol.951 , Issue.2 , pp. 336-340
    • Todorovic, S.M.1    Meyenburg, A.2    Jevtovic-Todorovic, V.3
  • 132
    • 0141850350 scopus 로고    scopus 로고
    • Reversal of experimental neuropathic pain by T-type calcium channel blockers
    • Dogrul, A.; Gardell, L.R.; Ossipov, M.H.; Tulunay, F.C.; Lai, J.; Porreca, F. Reversal of experimental neuropathic pain by T-type calcium channel blockers. Pain, 2003, 105(1-2), 159-168.
    • (2003) Pain , vol.105 , Issue.1-2 , pp. 159-168
    • Dogrul, A.1    Gardell, L.R.2    Ossipov, M.H.3    Tulunay, F.C.4    Lai, J.5    Porreca, F.6
  • 133
    • 0037189174 scopus 로고    scopus 로고
    • The role of T-type calcium channels in morphine analgesia, development of antinociceptive tolerance and dependence to morphine, and morphine abstinence syndrome
    • Dogrul, A.; Zagli, U.; Tulunay, F.C. The role of T-type calcium channels in morphine analgesia, development of antinociceptive tolerance and dependence to morphine, and morphine abstinence syndrome. Life Sci., 2002, 71(6), 725-734.
    • (2002) Life Sci , vol.71 , Issue.6 , pp. 725-734
    • Dogrul, A.1    Zagli, U.2    Tulunay, F.C.3
  • 134
    • 0035896186 scopus 로고    scopus 로고
    • (2+) channel blocker, on dorsal horn neuronal responses in rats
    • (2+) channel blocker, on dorsal horn neuronal responses in rats. Eur. J. Pharmacol., 2001, 415(2-3), 141-149.
    • (2001) Eur. J. Pharmacol. , vol.415 , Issue.2-3 , pp. 141-149
    • Matthews, E.A.1    Dickenson, A.H.2
  • 135
    • 1842786064 scopus 로고    scopus 로고
    • Ethosuximide reverses paclitaxel-and vincristine-induced painful peripheral neuropathy
    • Flatters, S.J.; Bennett, G.J. Ethosuximide reverses paclitaxel-and vincristine-induced painful peripheral neuropathy. Pain, 2004, 109(1-2), 150-161.
    • (2004) Pain , vol.109 , Issue.1-2 , pp. 150-161
    • Flatters, S.J.1    Bennett, G.J.2
  • 142
    • 84865263193 scopus 로고    scopus 로고
    • Common mechanisms of drug interactions with sodium and T-type calcium channels
    • Bladen, C.; Zamponi, G.W. Common mechanisms of drug interactions with sodium and T-type calcium channels. Mol. Pharmacol., 2012, 82(3), 481-487.
    • (2012) Mol. Pharmacol. , vol.82 , Issue.3 , pp. 481-487
    • Bladen, C.1    Zamponi, G.W.2
  • 143
    • 7044271164 scopus 로고    scopus 로고
    • Zonisamide: Chemistry, mechanism of action, and pharmacokinetics
    • discussion S10
    • Leppik, I.E. Zonisamide: chemistry, mechanism of action, and pharmacokinetics. Seizure, 2004, 13 Suppl 1, S5-9; discussion S10.
    • (2004) Seizure , vol.13 , pp. S5-S9
    • Leppik, I.E.1
  • 144
    • 3042716467 scopus 로고    scopus 로고
    • Successful use of zonisamide for central poststroke pain
    • Takahashi, Y.; Hashimoto, K.; Tsuji, S. Successful use of zonisamide for central poststroke pain. J. Pain, 2004, 5(3), 192-194.
    • (2004) J. Pain , vol.5 , Issue.3 , pp. 192-194
    • Takahashi, Y.1    Hashimoto, K.2    Tsuji, S.3
  • 145
    • 58849167209 scopus 로고    scopus 로고
    • Zonisamide block of cloned human T-type voltage-gated calcium channels
    • Matar, N.; Jin, W.; Wrubel, H.; Hescheler, J.; Schneider, T.; Weiergraber, M. Zonisamide block of cloned human T-type voltage-gated calcium channels. Epilepsy Res., 2009, 83(2-3), 224-234.
    • (2009) Epilepsy Res , vol.83 , Issue.2-3 , pp. 224-234
    • Matar, N.1    Jin, W.2    Wrubel, H.3    Hescheler, J.4    Schneider, T.5    Weiergraber, M.6
  • 146
    • 29844454212 scopus 로고    scopus 로고
    • The local anesthetic butamben inhibits and accelerates low-voltage activated T-type currents in small sensory neurons
    • Beekwilder, J.P.; van Kempen, G.T.; van den Berg, R.J.; Ypey, D.L. The local anesthetic butamben inhibits and accelerates low-voltage activated T-type currents in small sensory neurons. Anesth. Analg., 2006, 102(1), 141-145.
    • (2006) Anesth. Analg. , vol.102 , Issue.1 , pp. 141-145
    • Beekwilder, J.P.1    van Kempen, G.T.2    van den Berg, R.J.3    Ypey, D.L.4
  • 147
    • 26444550713 scopus 로고    scopus 로고
    • The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil
    • Barton, M.E.; Eberle, E.L.; Shannon, H.E. The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil. Eur. J. Pharmacol., 2005, 521(1-3), 79-85.
    • (2005) Eur. J. Pharmacol. , vol.521 , Issue.1-3 , pp. 79-85
    • Barton, M.E.1    Eberle, E.L.2    Shannon, H.E.3
  • 148
    • 0029918872 scopus 로고    scopus 로고
    • Anticonvulsant drug effects on spontaneous thalamocortical rhythms in vitro: Ethosuximide, trimethadione, and dimethadione
    • Zhang, Y.F.; Gibbs, J.W., 3rd; Coulter, D.A. Anticonvulsant drug effects on spontaneous thalamocortical rhythms in vitro: ethosuximide, trimethadione, and dimethadione. Epilepsy Res., 1996, 23(1), 15-36.
    • (1996) Epilepsy Res , vol.23 , Issue.1 , pp. 15-36
    • Zhang, Y.F.1    Gibbs, J.W.2    Coulter, D.A.3
  • 149
    • 70350335061 scopus 로고    scopus 로고
    • T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids
    • Barbara, G.; Alloui, A.; Nargeot, J.; Lory, P.; Eschalier, A.; Bourinet, E.; Chemin, J. T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids. J. Neurosci., 2009, 29(42), 13106-13114.
    • (2009) J. Neurosci. , vol.29 , Issue.42 , pp. 13106-13114
    • Barbara, G.1    Alloui, A.2    Nargeot, J.3    Lory, P.4    Eschalier, A.5    Bourinet, E.6    Chemin, J.7
  • 151
    • 20144373040 scopus 로고    scopus 로고
    • New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids
    • Pathirathna, S.; Brimelow, B.C.; Jagodic, M.M.; Krishnan, K.; Jiang, X.; Zorumski, C.F.; Mennerick, S.; Covey, D.F.; Todorovic, S.M.; Jevtovic-Todorovic, V. New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids. Pain, 2005, 114(3), 429-443.
    • (2005) Pain , vol.114 , Issue.3 , pp. 429-443
    • Pathirathna, S.1    Brimelow, B.C.2    Jagodic, M.M.3    Krishnan, K.4    Jiang, X.5    Zorumski, C.F.6    Mennerick, S.7    Covey, D.F.8    Todorovic, S.M.9    Jevtovic-Todorovic, V.10
  • 152
    • 0032249498 scopus 로고    scopus 로고
    • Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin
    • Chuang, R.S.; Jaffe, H.; Cribbs, L.; Perez-Reyes, E.; Swartz, K.J. Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin. Nat. Neurosci., 1998, 1(8), 668-674.
    • (1998) Nat. Neurosci. , vol.1 , Issue.8 , pp. 668-674
    • Chuang, R.S.1    Jaffe, H.2    Cribbs, L.3    Perez-Reyes, E.4    Swartz, K.J.5
  • 153
    • 0037088925 scopus 로고    scopus 로고
    • Kurtoxin, a gating modifier of neuronal high-and low-threshold ca channels
    • Sidach, S.S.; Mintz, I.M. Kurtoxin, a gating modifier of neuronal high-and low-threshold ca channels. J. Neurosci., 2002, 22(6), 2023-2034.
    • (2002) J. Neurosci. , vol.22 , Issue.6 , pp. 2023-2034
    • Sidach, S.S.1    Mintz, I.M.2
  • 156
    • 34948819283 scopus 로고    scopus 로고
    • Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers
    • Binshtok, A.M.; Bean, B.P.; Woolf, C.J. Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature, 2007, 449(7162), 607-610.
    • (2007) Nature , vol.449 , Issue.7162 , pp. 607-610
    • Binshtok, A.M.1    Bean, B.P.2    Woolf, C.J.3
  • 158
    • 84878507220 scopus 로고    scopus 로고
    • Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314
    • Puopolo, M.; Binshtok, A.M.; Yao, G.L.; Oh, S.B.; Woolf, C.J.; Bean, B.P. Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314. J. Neurophysiol., 2013, 109(7),1704-12.
    • (2013) J. Neurophysiol. , vol.109 , Issue.7 , pp. 1704-1712
    • Puopolo, M.1    Binshtok, A.M.2    Yao, G.L.3    Oh, S.B.4    Woolf, C.J.5    Bean, B.P.6
  • 159
    • 0028915242 scopus 로고
    • Inhibition of cardiac L-type calcium channels by quaternary amlodipine: Implications for pharmacokinetics and access to dihydropyridine binding site
    • Kwan, Y.W.; Bangalore, R.; Lakitsh, M.; Glossmann, H.; Kass, R.S. Inhibition of cardiac L-type calcium channels by quaternary amlodipine: implications for pharmacokinetics and access to dihydropyridine binding site. J. Mol. Cell Cardiol., 1995, 27(1), 253-262.
    • (1995) J. Mol. Cell Cardiol. , vol.27 , Issue.1 , pp. 253-262
    • Kwan, Y.W.1    Bangalore, R.2    Lakitsh, M.3    Glossmann, H.4    Kass, R.S.5
  • 160
    • 0024422497 scopus 로고
    • 2+ channel in vascular smooth muscle cells: Comparison with permanently charged derivative, D 890
    • 2+ channel in vascular smooth muscle cells: comparison with permanently charged derivative, D 890. Am. J. Physiol., 1989, 257(4 Pt 1), C689-695.
    • (1989) Am. J. Physiol. , vol.257 , Issue.4 , pp. C689-C695
    • Leblanc, N.1    Hume, J.R.2
  • 161
    • 25844456918 scopus 로고    scopus 로고
    • Targeting chronic and neuropathic pain: The N-type calcium channel comes of age
    • Snutch, T.P. Targeting chronic and neuropathic pain: the N-type calcium channel comes of age. NeuroRx, 2005, 2(4), 662-670.
    • (2005) Neurorx , vol.2 , Issue.4 , pp. 662-670
    • Snutch, T.P.1
  • 162
    • 84858054760 scopus 로고    scopus 로고
    • Imaging calcium in neurons
    • Grienberger, C.; Konnerth, A. Imaging calcium in neurons. Neuron, 2012, 73(5), 862-885.
    • (2012) Neuron , vol.73 , Issue.5 , pp. 862-885
    • Grienberger, C.1    Konnerth, A.2
  • 168
    • 0033136270 scopus 로고    scopus 로고
    • Lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS
    • Miwa, J.M.; Ibanez-Tallon, I.; Crabtree, G.W.; Sanchez, R.; Sali, A.; Role, L.W.; Heintz, N. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron, 1999, 23(1), 105-114.
    • (1999) Neuron , vol.23 , Issue.1 , pp. 105-114
    • Miwa, J.M.1    Ibanez-Tallon, I.2    Crabtree, G.W.3    Sanchez, R.4    Sali, A.5    Role, L.W.6    Heintz, N.7
  • 170
    • 4043180577 scopus 로고    scopus 로고
    • Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo
    • Ibanez-Tallon, I.; Wen, H.; Miwa, J.M.; Xing, J.; Tekinay, A.B.; Ono, F.; Brehm, P.; Heintz, N. Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron, 2004, 43(3), 305-311.
    • (2004) Neuron , vol.43 , Issue.3 , pp. 305-311
    • Ibanez-Tallon, I.1    Wen, H.2    Miwa, J.M.3    Xing, J.4    Tekinay, A.B.5    Ono, F.6    Brehm, P.7    Heintz, N.8
  • 173
    • 84874024139 scopus 로고    scopus 로고
    • First gene therapy nears landmark European market authorization
    • Moran, N. First gene therapy nears landmark European market authorization. Nat. Biotechnol., 2012, 30(9), 807-809.
    • (2012) Nat. Biotechnol. , vol.30 , Issue.9 , pp. 807-809
    • Moran, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.