DNA damage-centered signaling pathways are effectively activated during low dose-rate Auger radioimmunotherapy

Nuclear Medicine and Biology

Volumn 41, Issue S, 2014, Pages

  Piron, Bérengère ^a,b,c   Paillas, Salomé ^a,b,c   Boudousq, Vincent ^a,b,c   Pèlegrin, André ^a,b,c   Bascoul Mollevi, Caroline ^c   Chouin, Nicolas ^d   Navarro Teulon, Isabelle ^a,b,c   Pouget, Jean Pierre ^a,b,c  

^a INSTITUT DE RECHERCHE EN CANCÉROLOGIE DE MONTPELLIER   (France)

^b UNIV MONTPELLIER   (France)

^c CENTRE VAL D AURELLE   (France)

^d LUNAM UNIVERSITÉ   (France)

Author keywords

Auger electrons; DNA damage; Radioimmunotherapy; Signaling pathways

Indexed keywords

ATM PROTEIN; CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY I 125; EPIDERMAL GROWTH FACTOR RECEPTOR MONOCLONAL ANTIBODY I 125; GAMMA HISTONE H2AX; HISTONE H2AX; MONOCLONAL ANTIBODY I 125; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG; MONOCLONAL ANTIBODY; RADIOACTIVE IODINE;

APOPTOSIS; ARTICLE; AUGER RADIOIMMUNOTHERAPY; BIOACCUMULATION; CELL CYCLE PROGRESSION; CELL STRAIN HCT116; CELL SURVIVAL; CELLULAR DISTRIBUTION; COMET ASSAY; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOSIMETRY; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR SIGNALING; MICRONUCLEUS TEST; PROTEIN EXPRESSION; RADIATION ABSORPTION; RADIATION DOSE; RADIATION RESPONSE; RADIOIMMUNOTHERAPY; RADIOSENSITIVITY; SINGLE STRANDED DNA BREAK; SURVIVAL RATE; UPREGULATION; CELL NUCLEUS; DEFICIENCY; GENETICS; HCT116 CELL LINE; METABOLISM; PROCEDURES; SIGNAL TRANSDUCTION;

ABSORPTION, RADIATION; ANTIBODIES, MONOCLONAL; CELL NUCLEUS; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; HCT116 CELLS; HUMANS; IODINE RADIOISOTOPES; MICRONUCLEUS TESTS; RADIATION DOSAGE; RADIOIMMUNOTHERAPY; RADIOTHERAPY DOSAGE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84899124446     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2014.01.012     Document Type: Article

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