LIN7A depletion disrupts cerebral cortex development, contributing to intellectual disability in 12q21-deletion syndrome

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Matsumoto, Ayumi ^a   Mizuno, Makoto ^b   Hamada, Nanako ^b   Nozaki, Yasuyuki ^a   Jimbo, Eriko F ^a   Momoi, Mariko Y ^a   Nagata, Koh Ichi ^b   Yamagata, Takanori ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; LIN7A PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL MIGRATION; CELLULAR DISTRIBUTION; CHILD; CHROMOSOME 12Q; CHROMOSOME DELETION; CHROMOSOME DELETION 12Q21; COMPARATIVE GENOMIC HYBRIDIZATION; CORPUS CALLOSUM AGENESIS; EAR MALFORMATION; ELECTROPORATION; EMBRYO DEVELOPMENT; FEMALE; FRACTIONATION; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE SILENCING; GENETIC ASSOCIATION; HEART DISEASE; HEMISPHERE; HUMAN; HUMAN CELL; INTELLECTUAL IMPAIRMENT; JAPANESE; LIN7A GENE; MALE; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PERINATAL PERIOD; PRESYNAPTIC NERVE; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; WESTERN BLOTTING;

ANIMALS; AXONS; CELL CYCLE; CELL MOVEMENT; CERCOPITHECUS AETHIOPS; CEREBRAL CORTEX; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 12; COMPARATIVE GENOMIC HYBRIDIZATION; CORPUS CALLOSUM; COS CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INFANT; INTELLECTUAL DISABILITY; KARYOTYPING; MAGNETIC RESONANCE IMAGING; MALE; MEMBRANE PROTEINS; MICE; NEURAL STEM CELLS; NEURONS; RATS; RNA INTERFERENCE;

EID: 84899114745     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092695     Document Type: Article

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