Autologous cell seeded biodegradable scaffold for augmentation cystoplasty: Phase II study in children and adolescents with spina bifida

Journal of Urology

Volumn 191, Issue 5, 2014, Pages 1389-1395

  Joseph, David B ^a   Borer, Joseph G ^b   De Filippo, Roger E ^c   Hodges, Steve J ^e   McLorie, Gordon A ^d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e WAKE FOREST BAPTIST HEALTH   (United States)

Author keywords

autologous; neurogenic; regenerative medicine; spina bifida cystica; transplantation; urinary bladder; urologic surgical procedures

Indexed keywords

OXYBUTYNIN; TOLTERODINE;

ADOLESCENT; ADOLESCENT DISEASE; ARTICLE; AUTOLOGOUS CELL SEEDED BIODEGRADABLE SCAFFOLD; AUTOTRANSPLANTATION; BLADDER BIOPSY; BLADDER CAPACITY; BLADDER COMPLIANCE; BLADDER NECK; BLADDER RECONSTRUCTION; BLADDER RUPTURE; CELL GROWTH; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; EX VIVO STUDY; FEMALE; HUMAN; IMPLANTATION; INTESTINE OBSTRUCTION; MALE; NEUROGENIC BLADDER; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PATIENT SAFETY; PELVIS ABSCESS; PHASE 2 CLINICAL TRIAL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHOOL CHILD; SMOOTH MUSCLE FIBER; SPINAL DYSRAPHISM; SURGICAL TECHNIQUE; TISSUE REGENERATION; URINARY TRACT INFECTION; URINE INCONTINENCE; UROLOGICAL IMPLANT; EPITHELIUM CELL; HYDRONEPHROSIS; TISSUE SCAFFOLD; TREATMENT OUTCOME; UROTHELIUM; VESICOURETERAL REFLUX;

AUTOLOGOUS; NEUROGENIC; REGENERATIVE MEDICINE; SPINA BIFIDA CYSTICA; TRANSPLANTATION; URINARY BLADDER; UROLOGIC SURGICAL PROCEDURES;

ABSORBABLE IMPLANTS; ADOLESCENT; ANASTOMOSIS, SURGICAL; CELL TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; MALE; MUSCLE, SMOOTH; PROSPECTIVE STUDIES; SPINAL DYSRAPHISM; TISSUE SCAFFOLDS; TRANSPLANTATION, AUTOLOGOUS; URINARY BLADDER; URINARY BLADDER, NEUROGENIC; UROLOGIC SURGICAL PROCEDURES; UROTHELIUM;

EID: 84899102735     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2013.10.103     Document Type: Article

References (9)

1. A. Atala, S.M. Bauer, and S. Soker et al. Tissue-engineered autologous bladders for patients needing cystoplasty Lancet 367 2006 1241
2. C.D. Scales Jr., and J.S. Wiener Evaluating outcomes of enterocystoplasty in patients with spina bifida: a review of the literature J Urol 180 2008 2323
3. P.D. Metcalfe, and R.C. Rink Bladder augmentation: complications in the pediatric population Curr Urol Rep 8 2007 152
4. S.M. Gilbert, and T.W. Hensle Metabolic consequences and long-term complications of enterocystoplasty in children: a review J Urol 173 2005 1080
5. F. Oberpenning, J. Meng, and J.J. Yoo et al. De novo reconstitution of a functional mammalian urinary bladder by tissue engineering Nat Biotechnol 17 1999 149
6. M.J. Jayo, D. Jain, and J.W. Ludlow et al. Long-term durability, tissue regeneration and neo-organ growth during skeletal maturation with a neo-bladder augmentation construct Regen Med 3 2008 671
7. M. Kaefer, D. Zurakowski, and S.B. Bauer et al. Estimating normal bladder capacity in children J Urol 158 1997 2261
8. M.J. Jayo, D. Jain, and B.J. Wagner et al. Early cellular and stromal responses in regeneration versus repair of a mammalian bladder using autologous cell and biodegradable scaffold technologies J Urol 180 2008 392
9. R. Subramaniam, J. Hinley, and J. Stahlschmidt et al. Tissue engineering potential of urothelial cells from diseased bladders J Urol 186 2011 2014