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Volumn 3, Issue 1, 2014, Pages

An immunotherapeutic intervention against tumor progression: Targeting a driver of the epithelial-to-mesenchymal transition

Author keywords

Anticancer vaccines; Brachyury; EMT; Metastasis; Therapeutic resistance

Indexed keywords

CANCER VACCINE; CARCINOEMBRYONIC ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; PROSTATE SPECIFIC ANTIGEN; RECOMBINANT VACCINE; T BOX TRANSCRIPTION FACTOR; TUMOR ANTIGEN; UVOMORULIN;

EID: 84899099742     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/onci.27220     Document Type: Article
Times cited : (22)

References (10)
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  • 2
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  • 4
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    • The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells
    • PMID:20071775
    • Fernando RI, Litzinger M, Trono P, Hamilton DH, Schlom J, Palena C. The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. J Clin Invest 2010; 120:533-44; PMID:20071775; http://dx.doi. org/10.1172/JCI38379.
    • (2010) J Clin Invest , vol.120 , pp. 533-544
    • Fernando, R.I.1    Litzinger, M.2    Trono, P.3    Hamilton, D.H.4    Schlom, J.5    Palena, C.6
  • 5
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    • IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells
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    • Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C. IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells. Cancer Res 2011; 71:5296-306; PMID:21653678; http://dx.doi.org/10.1158/0008-5472.CAN-11-0156.
    • (2011) Cancer Res , vol.71 , pp. 5296-5306
    • Fernando, R.I.1    Castillo, M.D.2    Litzinger, M.3    Hamilton, D.H.4    Palena, C.5
  • 6
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    • The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies
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    • Huang B, Cohen JR, Fernando RI, Hamilton DH, Litzinger MT, Hodge JW, Palena C. The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies. Cell Death Dis 2013; 4:e682; PMID:23788039; http://dx.doi. org/10.1038/cddis.2013.208.
    • (2013) Cell Death Dis , vol.4
    • Huang, B.1    Cohen, J.R.2    Fernando, R.I.3    Hamilton, D.H.4    Litzinger, M.T.5    Hodge, J.W.6    Palena, C.7
  • 7
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    • An autocrine loop between TGF-β1 and the transcription factor brachyury controls the transition of human carcinoma cells into a mesenchymal phenotype
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    • Larocca C, Cohen JR, Fernando RI, Huang B, Hamilton DH, Palena C. An autocrine loop between TGF-β1 and the transcription factor brachyury controls the transition of human carcinoma cells into a mesenchymal phenotype. Mol Cancer Ther 2013; 12:1805-15; PMID:23783250; http://dx.doi. org/10.1158/1535-7163.MCT-12-1007.
    • (2013) Mol Cancer Ther , vol.12 , pp. 1805-1815
    • Larocca, C.1    Cohen, J.R.2    Fernando, R.I.3    Huang, B.4    Hamilton, D.H.5    Palena, C.6
  • 8
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    • The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell-mediated cancer immunotherapy
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    • Palena C, Polev DE, Tsang KY, Fernando RI, Litzinger M, Krukovskaya LL, Baranova AV, Kozlov AP, Schlom J. The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell-mediated cancer immunotherapy. Clin Cancer Res 2007; 13:2471-8; PMID:17438107; http://dx.doi.org/10.1158/1078-0432.CCR-06-2353.
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    • Palena, C.1    Polev, D.E.2    Tsang, K.Y.3    Fernando, R.I.4    Litzinger, M.5    Krukovskaya, L.L.6    Baranova, A.V.7    Kozlov, A.P.8    Schlom, J.9
  • 9
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    • Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer
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    • Roselli M, Fernando RI, Guadagni F, Spila A, Alessandroni J, Palmirotta R, Costarelli L, Litzinger M, Hamilton D, Huang B, et al. Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer. Clin Cancer Res 2012; 18:3868-79; PMID:22611028; http://dx.doi.org/10.1158/1078-0432.CCR-11-3211.
    • (2012) Clin Cancer Res , vol.18 , pp. 3868-3879
    • Roselli, M.1    Fernando, R.I.2    Guadagni, F.3    Spila, A.4    Alessandroni, J.5    Palmirotta, R.6    Costarelli, L.7    Litzinger, M.8    Hamilton, D.9    Huang, B.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.