PET imaging of focal demyelination and remyelination in a rat model of multiple sclerosis: Comparison of [11C]MeDAS, [11C]CIC and [11C]PIB

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 41, Issue 5, 2014, Pages 995-1003

  De Paula Faria, Daniele ^a,b   Copray, Sjef ^a   Sijbesma, Jurgen W A ^a   Willemsen, Antoon T M ^a   Buchpiguel, Carlos A ^b   Dierckx, Rudi A J O ^a   De Vries, Erik F J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Demyelination; Multiple sclerosis; Myelin; PET imaging; Remyelination

Indexed keywords

CASE IMAGING COMPOUND C 11; LYSOPHOSPHATIDYLCHOLINE; MYELIN; N METHYL 4,4' DIAMINOSTILBENE C 11; PITTSBURGH COMPOUND B; RADIOPHARMACEUTICAL AGENT; SODIUM CHLORIDE; TRACER; UNCLASSIFIED DRUG; ANILINE DERIVATIVE; BENZOTHIAZOLE DERIVATIVE; N-METHYL-2-(4'-METHYLAMINOPHENYL)-6-HYDROXYBENZOTHIAZOLE; N-METHYL-4,4'-DIAMINOSTILBENE; STILBENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; BRAIN REGION; CEREBELLUM; CONTROLLED STUDY; CORPUS CALLOSUM; CORPUS STRIATUM; DEMYELINATION; DENSITY; DISTRIBUTION VOLUME; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; IN VIVO STUDY; MALE; MULTIPLE SCLEROSIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; REMYELINIZATION; RIGHT HEMISPHERE; SPRAGUE DAWLEY RAT; WHITE MATTER; ANIMAL; COMPARATIVE STUDY; DIAGNOSTIC USE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; MYELIN SHEATH; SCINTISCANNING;

ANILINE COMPOUNDS; ANIMALS; BENZOTHIAZOLES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; MALE; MULTIPLE SCLEROSIS; MYELIN SHEATH; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; STILBENES;

EID: 84899084857     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-013-2682-6     Document Type: Article

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