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Volumn 44, Issue 5, 2014, Pages 1634-1642

Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance

Author keywords

ATP binding cassette subfamily G member 2; Masitinib; Multi drug resistance; Tyrosine kinase inihibitors

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CISPLATIN; DOXORUBICIN; FIRTECAN; MASITINIB; MITOXANTRONE; NILOTINIB;

EID: 84899070719     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2341     Document Type: Article
Times cited : (25)

References (79)
  • 1
    • 67650656774 scopus 로고    scopus 로고
    • Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: Evaluation of current strategies
    • Wu CP, Calcagno AM and Ambudkar SV: Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies. Curr Mol Pharmacol 1: 93-105, 2008.
    • (2008) Curr Mol Pharmacol , vol.1 , pp. 93-105
    • Wu, C.P.1    Calcagno, A.M.2    Ambudkar, S.V.3
  • 2
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman MM: Mechanisms of cancer drug resistance. Annu Rev Med 53: 615-627, 2002.
    • (2002) Annu Rev Med , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 3
    • 84934439469 scopus 로고    scopus 로고
    • Identification of molecular determinants of tumor sensitivity and resistance to anticancer drugs
    • Quintieri L, Fantin M and Vizler C: Identification of molecular determinants of tumor sensitivity and resistance to anticancer drugs. Adv Exp Med Biol 593: 95-104, 2007.
    • (2007) Adv Exp Med Biol , vol.593 , pp. 95-104
    • Quintieri, L.1    Fantin, M.2    Vizler, C.3
  • 4
    • 0035079539 scopus 로고    scopus 로고
    • Ceramide glycosylation potentiates cellular multidrug resistance
    • DOI 10.1096/fj.00-0223com
    • Liu YY, Han TY, Giuliano AE and Cabot MC: Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J 15: 719-730, 2001. (Pubitemid 32245990)
    • (2001) FASEB Journal , vol.15 , Issue.3 , pp. 719-730
    • Liu, Y.-Y.1    Han, T.-Y.2    Giuliano, A.E.3    Cabot, M.C.4
  • 5
    • 0027451668 scopus 로고
    • p53-Dependent apoptosis modulates the cytotoxicity of anticancer agents
    • DOI 10.1016/0092-8674(93)90719-7
    • Lowe SW, Ruley HE, Jacks T and Housman DE: p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967, 1993. (Pubitemid 23289454)
    • (1993) Cell , vol.74 , Issue.6 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 6
    • 0035038919 scopus 로고    scopus 로고
    • The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
    • DOI 10.1038/87912
    • Synold TW, Dussault I and Forman BM: The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med 7: 584-590, 2001. (Pubitemid 32448326)
    • (2001) Nature Medicine , vol.7 , Issue.5 , pp. 584-590
    • Synold, T.W.1    Dussault, I.2    Forman, B.M.3
  • 7
    • 33745835398 scopus 로고    scopus 로고
    • Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
    • DOI 10.1152/physrev.00035.2005
    • Deeley RG, Westlake C and Cole SP: Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol Rev 86: 849-899, 2006. (Pubitemid 44033384)
    • (2006) Physiological Reviews , vol.86 , Issue.3 , pp. 849-899
    • Deeley, R.G.1    Westlake, C.2    Cole, S.P.C.3
  • 8
    • 2942547591 scopus 로고    scopus 로고
    • DNA repair pathways in drug resistance in melanoma
    • DOI 10.1097/01.cad.0000127665.74096.93
    • Bradbury PA and Middleton MR: DNA repair pathways in drug resistance in melanoma. Anticancer Drugs 15: 421-426, 2004. (Pubitemid 38736939)
    • (2004) Anti-Cancer Drugs , vol.15 , Issue.5 , pp. 421-426
    • Bradbury, P.A.1    Middleton, M.R.2
  • 9
    • 31844443618 scopus 로고    scopus 로고
    • The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding
    • DOI 10.1016/j.febslet.2005.12.051, PII S0014579305015346, ABC Transporters
    • Ambudkar SV, Kim IW, Xia D and Sauna ZE: The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding. FEBS Lett 580: 1049-1055, 2006. (Pubitemid 43185285)
    • (2006) FEBS Letters , vol.580 , Issue.4 , pp. 1049-1055
    • Ambudkar, S.V.1    Kim, I.-W.2    Xia, D.3    Sauna, Z.E.4
  • 10
    • 73449126570 scopus 로고    scopus 로고
    • Mechanisms of chemotherapeutic drug resistance in cancer therapy - A quick review
    • Liu FS: Mechanisms of chemotherapeutic drug resistance in cancer therapy - a quick review. Taiwan J Obstet Gynecol 48: 239-244, 2009.
    • (2009) Taiwan J Obstet Gynecol , vol.48 , pp. 239-244
    • Liu, F.S.1
  • 11
    • 34250219965 scopus 로고    scopus 로고
    • Chemotherapy-induced resistance by ATP-binding cassette transporter genes
    • DOI 10.1016/j.bbcan.2007.05.002, PII S0304419X07000054
    • Gillet JP, Efferth T and Remacle J: Chemotherapy-induced resistance by ATP-binding cassette transporter genes. Biochim Biophys Acta 1775: 237-262, 2007. (Pubitemid 46899341)
    • (2007) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1775 , Issue.2 , pp. 237-262
    • Gillet, J.-P.1    Efferth, T.2    Remacle, J.3
  • 12
    • 33846688359 scopus 로고    scopus 로고
    • Structure and function of ABC transporters: The ATP switch provides flexible control
    • DOI 10.1007/s00424-006-0126-x, 20 years of ABC transporters
    • Linton KJ and Higgins CF: Structure and function of ABC transporters: the ATP switch provides flexible control. Pflugers Arch 453: 555-567, 2007. (Pubitemid 46192529)
    • (2007) Pflugers Archiv European Journal of Physiology , vol.453 , Issue.5 , pp. 555-567
    • Linton, K.J.1    Higgins, C.F.2
  • 13
    • 84863295466 scopus 로고    scopus 로고
    • Multidrug resistance associated proteins in multidrug resistance
    • Sodani K, Patel A, Kathawala RJ and Chen ZS: Multidrug resistance associated proteins in multidrug resistance. Chin J Cancer 31: 58-72, 2012.
    • (2012) Chin J Cancer , vol.31 , pp. 58-72
    • Sodani, K.1    Patel, A.2    Kathawala, R.J.3    Chen, Z.S.4
  • 15
    • 27644480743 scopus 로고    scopus 로고
    • Role of the breast cancer resistance protein (ABCG2) in drug transport
    • DOI 10.1208/aapsj070112, 12
    • Mao Q and Unadkat JD: Role of the breast cancer resistance protein (ABCG2) in drug transport. AAPS J 7: E118-E133, 2005. (Pubitemid 41554295)
    • (2005) AAPS Journal , vol.7 , Issue.1
    • Mao, Q.1    Unadkat, J.D.2
  • 16
    • 0038265441 scopus 로고    scopus 로고
    • ABCG2 transports sulfated conjugates of steroids and xenobiotics
    • DOI 10.1074/jbc.M212399200
    • Suzuki M, Suzuki H, Sugimoto Y and Sugiyama Y: ABCG2 transports sulfated conjugates of steroids and xenobiotics. J Biol Chem 278: 22644-22649, 2003. (Pubitemid 36830322)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22644-22649
    • Suzuki, M.1    Suzuki, H.2    Sugimoto, Y.3    Sugiyama, Y.4
  • 19
    • 0037113346 scopus 로고    scopus 로고
    • Localisation of breast cancer resistance protein in microvessel endothelium of human brain
    • DOI 10.1097/00001756-200211150-00014
    • Cooray HC, Blackmore CG, Maskell L and Barrand MA: Localisation of breast cancer resistance protein in microvessel endothelium of human brain. Neuroreport 13: 2059-2063, 2002. (Pubitemid 36005925)
    • (2002) NeuroReport , vol.13 , Issue.16 , pp. 2059-2063
    • Cooray, H.C.1    Blackmore, C.G.2    Maskell, L.3    Barrand, M.A.4
  • 21
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
    • DOI 10.1016/S0169-409X(02)00169-2, PII S0169409X02001692
    • Schinkel AH and Jonker JW: Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv Drug Deliv Rev 55: 3-29, 2003. (Pubitemid 36078452)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.1 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 22
    • 0035685449 scopus 로고    scopus 로고
    • Complete characterization of the human ABC gene family
    • DOI 10.1023/A:1012823120935
    • Dean M and Allikmets R: Complete characterization of the human ABC gene family. J Bioenerg Biomembr 33: 475-479, 2001. (Pubitemid 34052573)
    • (2001) Journal of Bioenergetics and Biomembranes , vol.33 , Issue.6 , pp. 475-479
    • Dean, M.1    Allikmets, R.2
  • 24
    • 0042354831 scopus 로고    scopus 로고
    • Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport
    • Chen ZS, Robey RW, Belinsky MG, et al: Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport. Cancer Res 63: 4048-4054, 2003. (Pubitemid 36917926)
    • (2003) Cancer Research , vol.63 , Issue.14 , pp. 4048-4054
    • Chen, Z.-S.1    Robey, R.W.2    Belinsky, M.G.3    Shchaveleva, I.4    Ren, X.-Q.5    Sugimoto, Y.6    Ross, D.D.7    Bates, S.E.8    Kruh, G.D.9
  • 26
    • 67349207358 scopus 로고    scopus 로고
    • Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2
    • Dai CL, Liang YJ, Wang YS, et al: Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2. Cancer Lett 279: 74-83, 2009.
    • (2009) Cancer Lett , vol.279 , pp. 74-83
    • Dai, C.L.1    Liang, Y.J.2    Wang, Y.S.3
  • 28
    • 0036792874 scopus 로고    scopus 로고
    • Multidrug resistance and cancer: The role of the human ABC transporter ABCG2
    • DOI 10.2174/1389203023380521
    • Ejendal KF and Hrycyna CA: Multidrug resistance and cancer: the role of the human ABC transporter ABCG2. Curr Protein Pept Sci 3: 503-511, 2002. (Pubitemid 35157721)
    • (2002) Current Protein and Peptide Science , vol.3 , Issue.5 , pp. 503-511
    • Ejendal, K.F.K.1    Hrycyna, C.A.2
  • 29
    • 84866704415 scopus 로고    scopus 로고
    • Regulation and expression of the ATP-binding cassette transporter ABCG2 in human embryonic stem cells
    • Padmanabhan R, Chen KG, Gillet JP, et al: Regulation and expression of the ATP-binding cassette transporter ABCG2 in human embryonic stem cells. Stem Cells 30: 2175-2187, 2012.
    • (2012) Stem Cells , vol.30 , pp. 2175-2187
    • Padmanabhan, R.1    Chen, K.G.2    Gillet, J.P.3
  • 30
    • 34047162390 scopus 로고    scopus 로고
    • Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors
    • DOI 10.1124/dmd.106.011478
    • Evseenko DA, Paxton JW and Keelan JA: Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors. Drug Metab Dispos 35: 595-601, 2007. (Pubitemid 46513262)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.4 , pp. 595-601
    • Evseenko, D.A.1    Paxton, J.W.2    Keelan, J.A.3
  • 32
    • 54249157033 scopus 로고    scopus 로고
    • Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2
    • Dai CL, Tiwari AK, Wu CP, et al: Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2. Cancer Res 68: 7905-7914, 2008.
    • (2008) Cancer Res , vol.68 , pp. 7905-7914
    • Dai, C.L.1    Tiwari, A.K.2    Wu, C.P.3
  • 33
    • 84896298982 scopus 로고    scopus 로고
    • Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs
    • Oct 9, (Epub ahead of print)
    • Kathawala RJ, Wang YJ, Ashby Jr CR and Chen ZS: Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs. Chin J Cancer: Oct 9, 2013 (Epub ahead of print).
    • (2013) Chin J Cancer
    • Kathawala, R.J.1    Wang, Y.J.2    Ashby Jr., C.R.3    Chen, Z.S.4
  • 34
    • 84876239961 scopus 로고    scopus 로고
    • Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10)
    • Deng W, Dai CL, Chen JJ, et al: Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10). Oncol Rep 29: 2479-2485, 2013.
    • (2013) Oncol Rep , vol.29 , pp. 2479-2485
    • Deng, W.1    Dai, C.L.2    Chen, J.J.3
  • 36
    • 84896301932 scopus 로고    scopus 로고
    • Tivozanib reverses multidrug resistance mediated by ABCB1 (P-glycoprotein) and ABCG2 (BCRP)
    • Dec 3, Epub ahead of print
    • Yang D, Kathawala RJ, Chufan EE, et al: Tivozanib reverses multidrug resistance mediated by ABCB1 (P-glycoprotein) and ABCG2 (BCRP). Future Oncol: Dec 3, 2013 (Epub ahead of print).
    • (2013) Future Oncol
    • Yang, D.1    Kathawala, R.J.2    Chufan, E.E.3
  • 37
    • 70449564331 scopus 로고    scopus 로고
    • Imatinib and nilotinib reverse multidrug resistance in cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10)
    • Shen T, Kuang YH, Ashby CR, et al: Imatinib and nilotinib reverse multidrug resistance in cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10). PLoS One 4: e7520, 2009.
    • (2009) PLoS One , vol.4
    • Shen, T.1    Kuang, Y.H.2    Ashby, C.R.3
  • 38
    • 65649084180 scopus 로고    scopus 로고
    • Nilotinib (AMN107, Tasigna) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters
    • Tiwari AK, Sodani K, Wang SR, et al: Nilotinib (AMN107, Tasigna) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters. Biochem Pharmacol 78: 153-161, 2009.
    • (2009) Biochem Pharmacol , vol.78 , pp. 153-161
    • Tiwari, A.K.1    Sodani, K.2    Wang, S.R.3
  • 40
    • 84861980282 scopus 로고    scopus 로고
    • Masitinib treatment in patients with progressive multiple sclerosis: A randomized pilot study
    • Vermersch P, Benrabah R, Schmidt N, et al: Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot study. BMC Neurol 12: 36, 2012.
    • (2012) BMC Neurol , vol.12 , pp. 36
    • Vermersch, P.1    Benrabah, R.2    Schmidt, N.3
  • 41
    • 84878321089 scopus 로고    scopus 로고
    • Management of secondary progressive multiple sclerosis: Prophylactic treatment-past, present, and future aspects
    • Rommer PS and Stuve O: Management of secondary progressive multiple sclerosis: prophylactic treatment-past, present, and future aspects. Curr Treat Options Neurol 15: 241-258, 2013.
    • (2013) Curr Treat Options Neurol , vol.15 , pp. 241-258
    • Rommer, P.S.1    Stuve, O.2
  • 42
    • 67650314629 scopus 로고    scopus 로고
    • Masitinib, a c-kit/PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics
    • Humbert M, de Blay F, Garcia G, et al: Masitinib, a c-kit/PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics. Allergy 64: 1194-1201, 2009.
    • (2009) Allergy , vol.64 , pp. 1194-1201
    • Humbert, M.1    De Blay, F.2    Garcia, G.3
  • 43
    • 84859416461 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma
    • Lee-Fowler TM, Guntur V, Dodam J, Cohn LA, DeClue AE and Reinero CR: The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma. Int Arch Allergy Immunol 158: 369-374, 2012.
    • (2012) Int Arch Allergy Immunol , vol.158 , pp. 369-374
    • Lee-Fowler, T.M.1    Guntur, V.2    Dodam, J.3    Cohn, L.A.4    DeClue, A.E.5    Reinero, C.R.6
  • 44
    • 67649890634 scopus 로고    scopus 로고
    • Masitinib in the treatment of active rheumatoid arthritis: Results of a multicentre, openlabel, dose-ranging, phase 2a study
    • Tebib J, Mariette X, Bourgeois P, et al: Masitinib in the treatment of active rheumatoid arthritis: results of a multicentre, openlabel, dose-ranging, phase 2a study. Arthritis Res Ther 11: R95, 2009.
    • (2009) Arthritis Res Ther , vol.11
    • Tebib, J.1    Mariette, X.2    Bourgeois, P.3
  • 45
    • 67650904196 scopus 로고    scopus 로고
    • More about masitinib
    • Walker UA: More about masitinib. Arthritis Res Ther 11: 120, 2009.
    • (2009) Arthritis Res Ther , vol.11 , pp. 120
    • Walker, U.A.1
  • 46
    • 84862578484 scopus 로고    scopus 로고
    • Mast cell leukemia: Identification of a new c-Kit mutation, dup(501-502), and response to masitinib, a c-Kit tyrosine kinase inhibitor
    • Georgin-Lavialle S, Lhermitte L, Suarez F, et al: Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to masitinib, a c-Kit tyrosine kinase inhibitor. Eur J Haematol 89: 47-52, 2012.
    • (2012) Eur J Haematol , vol.89 , pp. 47-52
    • Georgin-Lavialle, S.1    Lhermitte, L.2    Suarez, F.3
  • 47
    • 78649504351 scopus 로고    scopus 로고
    • Masitinib for the treatment of systemic and cutaneous mastocytosis with handicap: A phase 2a study
    • Paul C, Sans B, Suarez F, et al: Masitinib for the treatment of systemic and cutaneous mastocytosis with handicap: a phase 2a study. Am J Hematol 85: 921-925, 2010.
    • (2010) Am J Hematol , vol.85 , pp. 921-925
    • Paul, C.1    Sans, B.2    Suarez, F.3
  • 48
    • 77951878436 scopus 로고    scopus 로고
    • Phase II study of oral masitinib mesilate in imatinib-naive patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST)
    • Le Cesne A, Blay JY, Bui BN, et al: Phase II study of oral masitinib mesilate in imatinib-naive patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST). Eur J Cancer 46: 1344-1351, 2010.
    • (2010) Eur J Cancer , vol.46 , pp. 1344-1351
    • Le Cesne, A.1    Blay, J.Y.2    Bui, B.N.3
  • 49
    • 77953048032 scopus 로고    scopus 로고
    • Safety and activity of masitinib in combination with gemcitabine in patients with advanced pancreatic cancer
    • Mitry E, Hammel P, Deplanque G, et al: Safety and activity of masitinib in combination with gemcitabine in patients with advanced pancreatic cancer. Cancer Chemother Pharmacol 66: 395-403, 2010.
    • (2010) Cancer Chemother Pharmacol , vol.66 , pp. 395-403
    • Mitry, E.1    Hammel, P.2    Deplanque, G.3
  • 50
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T and Bates SE: Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2: 48-58, 2002. (Pubitemid 37328807)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 53
    • 0023130372 scopus 로고
    • Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
    • Carmichael J, DeGraff WG, Gazdar AF, Minna JD and Mitchell JB: Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47: 936-942, 1987. (Pubitemid 17027905)
    • (1987) Cancer Research , vol.47 , Issue.4 , pp. 936-942
    • Carmichael, J.1    DeGraff, W.G.2    Gazdar, A.F.3
  • 54
    • 41649122089 scopus 로고    scopus 로고
    • Homology modeling of breast cancer resistance protein (ABCG2)
    • Hazai E and Bikadi Z: Homology modeling of breast cancer resistance protein (ABCG2). J Struct Biol 162: 63-74, 2008.
    • (2008) J Struct Biol , vol.162 , pp. 63-74
    • Hazai, E.1    Bikadi, Z.2
  • 55
    • 4544275886 scopus 로고    scopus 로고
    • 482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing binding
    • DOI 10.1042/BJ20040355
    • Alqawi O, Bates S and Georges E: Arginine482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing binding. Biochem J 382: 711-716, 2004. (Pubitemid 39243937)
    • (2004) Biochemical Journal , vol.382 , Issue.2 , pp. 711-716
    • Alqawi, O.1    Bates, S.2    Georges, E.3
  • 56
    • 84864408192 scopus 로고    scopus 로고
    • Zafirlukast antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance
    • Sun YL, Kathawala RJ, Singh S, et al: Zafirlukast antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance. Anticancer Drugs 23: 865-873, 2012.
    • (2012) Anticancer Drugs , vol.23 , pp. 865-873
    • Sun, Y.L.1    Kathawala, R.J.2    Singh, S.3
  • 59
    • 0034684120 scopus 로고    scopus 로고
    • Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan
    • Jonker JW, Smit JW, Brinkhuis RF, et al: Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan. J Natl Cancer Inst 92: 1651-1656, 2000.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1651-1656
    • Jonker, J.W.1    Smit, J.W.2    Brinkhuis, R.F.3
  • 61
    • 59649129538 scopus 로고    scopus 로고
    • Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2
    • Shukla S, Robey RW, Bates SE and Ambudkar SV: Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. Drug Metab Dispos 37: 359-365, 2009.
    • (2009) Drug Metab Dispos , vol.37 , pp. 359-365
    • Shukla, S.1    Robey, R.W.2    Bates, S.E.3    Ambudkar, S.V.4
  • 62
    • 78049281857 scopus 로고    scopus 로고
    • Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters
    • Mi YJ, Liang YJ, Huang HB, et al: Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters. Cancer Res 70: 7981-7991, 2010.
    • (2010) Cancer Res , vol.70 , pp. 7981-7991
    • Mi, Y.J.1    Liang, Y.J.2    Huang, H.B.3
  • 63
    • 59049099685 scopus 로고    scopus 로고
    • QSAR analysis and molecular modeling of ABCG2-specific inhibitors
    • Nicolle E, Boumendjel A, Macalou S, et al: QSAR analysis and molecular modeling of ABCG2-specific inhibitors. Adv Drug Deliv Rev 61: 34-46, 2009.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 34-46
    • Nicolle, E.1    Boumendjel, A.2    Macalou, S.3
  • 64
    • 71049156626 scopus 로고    scopus 로고
    • ABCG2: The key to chemoresistance in cancer stem cells?
    • An Y and Ongkeko WM: ABCG2: the key to chemoresistance in cancer stem cells? Expert Opin Drug Metab Toxicol 5: 1529-1542, 2009.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 1529-1542
    • An, Y.1    Ongkeko, W.M.2
  • 65
    • 79959548959 scopus 로고    scopus 로고
    • Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells
    • Chen YJ, Huang WC, Wei YL, et al: Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells. PLoS One 6: e21428, 2011.
    • (2011) PLoS One , vol.6
    • Chen, Y.J.1    Huang, W.C.2    Wei, Y.L.3
  • 66
    • 84858002750 scopus 로고    scopus 로고
    • Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
    • Natarajan K, Xie Y, Baer MR and Ross DD: Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance. Biochem Pharmacol 83: 1084-1103, 2012.
    • (2012) Biochem Pharmacol , vol.83 , pp. 1084-1103
    • Natarajan, K.1    Xie, Y.2    Baer, M.R.3    Ross, D.D.4
  • 67
    • 80053436675 scopus 로고    scopus 로고
    • The ABCG family of membrane-associated transporters: You don't have to be big to be mighty
    • Kerr ID, Haider AJ and Gelissen IC: The ABCG family of membrane-associated transporters: you don't have to be big to be mighty. Br J Pharmacol 164: 1767-1779, 2011.
    • (2011) Br J Pharmacol , vol.164 , pp. 1767-1779
    • Kerr, I.D.1    Haider, A.J.2    Gelissen, I.C.3
  • 70
    • 80052495026 scopus 로고    scopus 로고
    • ABCG transporters and disease
    • Woodward OM, Kottgen A and Kottgen M: ABCG transporters and disease. FEBS J 278: 3215-3225, 2011.
    • (2011) FEBS J , vol.278 , pp. 3215-3225
    • Woodward, O.M.1    Kottgen, A.2    Kottgen, M.3
  • 71
    • 33947580644 scopus 로고    scopus 로고
    • Human multidrug transporter ABCG2, a target for sensitizing drug resistance in cancer chemotherapy
    • DOI 10.2174/092986707780059580
    • Xu J, Peng H and Zhang JT: Human multidrug transporter ABCG2, a target for sensitizing drug resistance in cancer chemotherapy. Curr Med Chem 14: 689-701, 2007. (Pubitemid 46477721)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.6 , pp. 689-701
    • Xu, J.1    Peng, H.2    Zhang, J.-T.3
  • 72
    • 84861018126 scopus 로고    scopus 로고
    • Prognostic value of the stem cell markers CD133 and ABCG2 expression in esophageal squamous cell carcinoma
    • Hang D, Dong HC, Ning T, Dong B, Hou DL and Xu WG: Prognostic value of the stem cell markers CD133 and ABCG2 expression in esophageal squamous cell carcinoma. Dis Esophagus 25: 638-644, 2012.
    • (2012) Dis Esophagus , vol.25 , pp. 638-644
    • Hang, D.1    Dong, H.C.2    Ning, T.3    Dong, B.4    Hou, D.L.5    Xu, W.G.6
  • 73
    • 74949118645 scopus 로고    scopus 로고
    • Expression of MRP1, BCRP, LRP, and ERCC1 in advanced non-small-cell lung cancer: Correlation with response to chemotherapy and survival
    • Li J, Li ZN, Du YJ, Li XQ, Bao QL and Chen P: Expression of MRP1, BCRP, LRP, and ERCC1 in advanced non-small-cell lung cancer: correlation with response to chemotherapy and survival. Clin Lung Cancer 10: 414-421, 2009.
    • (2009) Clin Lung Cancer , vol.10 , pp. 414-421
    • Li, J.1    Li, Z.N.2    Du, Y.J.3    Li, X.Q.4    Bao, Q.L.5    Chen, P.6
  • 74
    • 34548071672 scopus 로고    scopus 로고
    • ABCG2 expression is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma
    • Tsunoda S, Okumura T, Ito T, et al: ABCG2 expression is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma. Oncology 71: 251-258, 2006.
    • (2006) Oncology , vol.71 , pp. 251-258
    • Tsunoda, S.1    Okumura, T.2    Ito, T.3
  • 75
    • 0036163796 scopus 로고    scopus 로고
    • ABC transporters as phenotypic markers and functional regulators of stem cells
    • Bunting KD: ABC transporters as phenotypic markers and functional regulators of stem cells. Stem Cells 20: 11-20, 2002.
    • (2002) Stem Cells , vol.20 , pp. 11-20
    • Bunting, K.D.1
  • 76
    • 0036154828 scopus 로고    scopus 로고
    • The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
    • Kim M, Turnquist H, Jackson J, et al: The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 8: 22-28, 2002. (Pubitemid 34101455)
    • (2002) Clinical Cancer Research , vol.8 , Issue.1 , pp. 22-28
    • Kim, M.1    Turnquist, H.2    Jackson, J.3    Sgagias, M.4    Yan, Y.5    Gong, M.6    Dean, M.7    Sharp, J.G.8    Cowan, K.9
  • 77
    • 33846664466 scopus 로고    scopus 로고
    • ATP-binding cassette, subfamily G (ABCG family)
    • DOI 10.1007/s00424-006-0134-x, 20 years of ABC transporters
    • Kusuhara H and Sugiyama Y: ATP-binding cassette, subfamily G (ABCG family). Pflugers Arch 453: 735-744, 2007. (Pubitemid 46192543)
    • (2007) Pflugers Archiv European Journal of Physiology , vol.453 , Issue.5 , pp. 735-744
    • Kusuhara, H.1    Sugiyama, Y.2
  • 78
    • 77951224759 scopus 로고    scopus 로고
    • ABCG2: A potential marker of stem cells and novel target in stem cell and cancer therapy
    • Ding XW, Wu JH and Jiang CP: ABCG2: a potential marker of stem cells and novel target in stem cell and cancer therapy. Life Sci 86: 631-637, 2010.
    • (2010) Life Sci , vol.86 , pp. 631-637
    • Ding, X.W.1    Wu, J.H.2    Jiang, C.P.3
  • 79
    • 42749084961 scopus 로고    scopus 로고
    • Characterization of a stem cell population in lung cancer A549 cells
    • Sung JM, Cho HJ, Yi H, et al: Characterization of a stem cell population in lung cancer A549 cells. Biochem Biophys Res Commun 371: 163-167, 2008.
    • (2008) Biochem Biophys Res Commun , vol.371 , pp. 163-167
    • Sung, J.M.1    Cho, H.J.2    Yi, H.3


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