A systematic review on effectiveness and safety of eliglustat for type 1 Gaucher disease

Expert Opinion on Orphan Drugs

Volumn 2, Issue 5, 2014, Pages 523-529

  Smid, Bouwien E ^a   Hollak, Carla E M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Eliglustat (tartrate); Gaucher disease; Lysosomal storage disorder; Substrate reduction therapy

Indexed keywords

CYTOCHROME P450 2D6; ELIGLUSTAT; HEMOGLOBIN; IMIGLUCERASE; MIGLUSTAT; PLACEBO;

ABDOMINAL PAIN; ARTICLE; BONE DISEASE; BRADYCARDIA; CLINICAL EFFECTIVENESS; COMPARATIVE EFFECTIVENESS; DIARRHEA; DISEASE SEVERITY; DIZZINESS; DOSAGE SCHEDULE COMPARISON; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; DRUG WITHDRAWAL; ENZYME REPLACEMENT; FATIGUE; GAUCHER DISEASE; GAUCHER TYPE 1 DISEASE; HEADACHE; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART PALPITATION; HEART VENTRICLE TACHYCARDIA; HUMAN; LIVER WEIGHT; NAUSEA; NONHUMAN; POLYNEUROPATHY; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; SECOND DEGREE ATRIOVENTRICULAR BLOCK; SPLEEN WEIGHT; SPONTANEOUS ABORTION; SYSTEMATIC REVIEW; TACHYCARDIA; THROMBOCYTE; THROMBOCYTOPENIA; VOMITING;

EID: 84899070142     PISSN: None     EISSN: 21678707     Source Type: Journal    
DOI: 10.1517/21678707.2014.899148     Document Type: Article

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