Empathy, depressive symptoms, and social functioning among individuals with schizophrenia

Psychiatry Research

Volumn 216, Issue 3, 2014, Pages 325-332

  Abramowitz, Amy C ^a   Ginger, Emily J ^a   Gollan, Jackie K ^a   Smith, Matthew J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Depressive symptoms; Empathy; Personal distress; Schizophrenia; Social functioning

Indexed keywords

ARIPIPRAZOLE; ASENAPINE; CLOZAPINE; FLUPHENAZINE; HALOPERIDOL; OLANZAPINE; PALIPERIDONE; PERPHENAZINE; QUETIAPINE; RISPERIDONE; ZIPRASIDONE;

ADULT; ARTICLE; CLINICAL ASSESSMENT TOOL; CLINICAL FEATURE; COGNITIVE DEFECT; CONTROLLED STUDY; DEPRESSION; DISEASE EXACERBATION; DISTRESS SYNDROME; EMPATHY; FEMALE; HUMAN; INTERPERSONAL REACTIVITY INDEX; MAJOR CLINICAL STUDY; MALE; MOOD DISORDER; PATIENT ASSESSMENT; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; PSYCHOSIS; SCHIZOPHRENIA; SCORING SYSTEM; SELF REPORT; SOCIAL DISABILITY; SOCIAL INTERACTION; SYMPTOM; COGNITION; COMORBIDITY; DISEASE ASSOCIATION; EMOTION; RATING SCALE; SELF CONCEPT; SYMPTOMATOLOGY;

DEPRESSIVE SYMPTOMS; EMPATHY; PERSONAL DISTRESS; SCHIZOPHRENIA; SOCIAL FUNCTIONING;

ADULT; DEPRESSION; EMOTIONS; EMPATHY; FEMALE; HUMANS; MALE; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SELF REPORT; SOCIAL ADJUSTMENT;

EID: 84899068100     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2014.02.028     Document Type: Article

References (64)

1. Achim A.M., Ouellet R., Roy M.A., Jackson P.L. Assessment of empathy in first-episode psychosis and meta-analytic comparison with previous studies in schizophrenia. Psychiatry Research 2011, 190(1):3-8.
2. Aguilar E.J., Siris S.G. Do antipsychotic drugs influence suicidal behavior in schizophrenia?. Psychopharmacology Bulletin 2007, 40(3):128-142.
3. Andreasen N.C. The Scale for the Assessment of Negative Symptoms 1983, The University of Iowa, Iowa City, IA.
4. Andreasen N.C. The Scale for the Assessment of Positive Symptoms 1983, The University of Iowa, Iowa City, IA.
5. Baez S., Herrera E., Villarin L., Theil D., Gonzalez-Gadea M.L., Gomez P., Mosquera M., Huepe D., Strejilevich S., Vigliecca N.S., Matthaus F., Decety J., Manes F., Ibanez A.M. Contextual social cognition impairments in schizophrenia and bipolar disorder. PLoS One 2013, 8(3):e57664.
6. Barch D.M., Mitropoulou V., Harvey P.D., New A.S., Silverman J.M., Siever L.J. Context-processing deficits in schizotypal personality disorder. Journal of Abnormal Psychology 2004, 113(4):556-568.
7. Beck A. The past and future of cognitive therapy. Journal of Psychotherapy Practice and Research 1996, 6(4):276-284.
8. Benton A.L., Hamsher K., Sivan A.B. Multilingual Aphasia Examination 1976, AJA Associates, Iowa City.
9. Birchwood M., Iqbal Z., Upthegrove R. Psychological pathways to depression in schizophrenia: studies in acute psychosis, post psychotic depression and auditory hallucinations. European Archives of Psychiatry and Clinical Neuroscience 2005, 255:202-212.
10. Bondolfi G., Jermann F., Rouget B.W., Gex-Fabry M., McQuillan A., Dupont-Willemin A., Aubry J.M., Nguyen C. Self- and clinician-rated Montgomery-Asberg Depression Rating Scale: evaluation in clinical practice. Journal of Affective Disorders 2010, 121(3):268-272.
11. Brown J.F., Brown M.Z., Dibiasio P. Treating Individuals with intellectual disabilities and challenging behaviors with adapted dialectical behavior therapy. Journal of Mental Health Research in Intellectual Disabilities 2013, 6(4):280-303.
12. Brune M., Brune-Cohrs U. Theory of mind-evolution, ontogeny, brain mechanisms and psychopathology. Neuroscience and Biobehavioral Reviews 2006, 30(4):437-455.
13. Buckley P.F., Miller B.J., Lehrer D.S., Castle D.J. Psychiatric comorbidities and schizophrenia. Schizophrenia Bulletin 2009, 35(2):383-402.
14. Cohen, C.I., Izediuno, I., Yadack, A.M., Ghosh, B., Garrett, M., 2013. Characteristics of auditory hallucinations and associated factors in older adults with schizophrenia, American Journal of Geriatric Psychiatry, electronic publication 7 September; http://dx.doi.org/10.1016/j.jagp.2013.07.001.
15. Cusi A.M., Macqueen G.M., Spreng R.N., McKinnon M.C. Altered empathic responding in major depressive disorder: relation to symptom severity, illness burden, and psychosocial outcome. Psychiatry Research 2011, 188(2):231-236.
16. Davis M.H. Measuring individual differences in empathy: evidence for a multidimensional approach. Journal of Personality and Social Psychology 1983, 44(1):113-126.
17. Decety J. Dissecting the neural mechanisms mediating empathy. Emotion Review 2011, 3(1):92-108.
18. Decety J., Jackson P.L. The functional architecture of human empathy. Behavioral and Cognitive Neuroscience Reviews 2004, 3(2):71-100.
19. Delis D., Kramer J.H., Kaplan E., Ober B. California Verbal Learning Test, Research Edition 1983, The Psychological Corporation, Cleveland.
20. Derntl B., Finkelmeyer A., Toygar T.K., Hulsmann A., Schneider F., Falkenberg D.I., Habel U. Generalized deficit in all core components of empathy in schizophrenia. Schizophrenia Research 2009, 108(1-3):197-206.
21. Derntl B., Seidel E.M., Schneider F., Habel U. How specific are emotional deficits? A comparison of empathic abilities in schizophrenia, bipolar and depressed patients. Schizophrenia Research 2012, 142(1-3):58-64.
22. Eisenberg N., Eggum N.D. Empathic Responding: Sympathy and Personal Distress. The Social Neuroscience of Empathy 2009, 71-84. The MIT Press, Cambridge, MA. J. Decety, W. Ickes (Eds.).
23. Fervaha G., Agid O., Takeuchi H., Foussias G., Remington G. Clinical determinants of life satisfaction in chronic schizophrenia: data from the CATIE study. Schizophrenia Research 2013, 151(1-3):203-208.
24. Fieller, N., 2005. Multivariate outliers. In: Everitt, B.S., Howell, D.C. (Eds.), Encyclopedia of Statistics in Behavioral Science, vol. 3. John Wiley & Sons, Ltd, Chichester, pp. 1379-1384.
25. First M.B., Spitzer R.L., Miriam G., Williams J.B.W. Structured clinical interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition 2002, Biometrics Research, New York State Psychiatric Institute, New York, NY.
26. Gur R.C., Sara R., Hagendoorn M., Marom O., Hughett P., Macy L., Turner T., Bajcsy R., Posner A., Gur R.E. A method for obtaining 3-dimensional facial expressions and its standardization for use in neurocognitive studies. Journal of Neuroscience Methods 2002, 115(2):137-143.
27. Haker H., Schimansky J., Jann S., Rössler W. Self-reported empathic abilities in schizophrenia: a longitudinal perspective. Psychiatry Research 2012, 200(2-3):1028-1031.
28. Harvey P.D., Velligan D.I., Bellack A.S. Performance-based measures of functional skills: usefulness in clinical treatment studies. Schizophrenia Bulletin 2007, 33(5):1138-1148.
29. Ickes W., Buysse A.H.P., Rivers K., Erickson J., Hankock M., Kelleher J., Gesn P.R. On the difficulty of distinguishing "good" and "poor" perceivers: a social relations analysis of empathic accuracy data. Personal Relationships 2000, 7:219-234.
30. Kasckow J., Lanouette N., Patterson T., Fellows I., Golshan S., Solorzano E., Zisook S. Treatment of subsyndromal depressive symptoms in middle-aged and older adults with schizophrenia: effect on functioning. International Journal of Geriatric Psychiatry 2010, 25(2):183-190.
31. Kessler R.C., Berglund P., Demler O., Jin R., Koretz D., Merikangas K.R., Rush A.J., Walters E.E., Wang P.S. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). Journal of the American Medical Association 2003, 289(23):3095-3105.
32. Khoury B., Lecomte T., Comtois G., Nicole L. Third-wave strategies for emotion regulation in early psychosis: a pilot study. Early Intervention in Psychiatry 2013.
33. Lançon C., Auquier P., Reine G., Bernard D., Addington D. Relationships between depression and psychotic symptoms of schizophrenia during an acute episode and stable period. Schizophrenia Research 2001, 47(2-3):135-140.
34. Langdon R., Coltheart M., Ward P.B. Empathetic perspective-taking is impaired in schizophrenia: evidence from a study of emotion attribution and theory of mind. Cognitive Neuropsychiatry 2006, 11(2):133-155.
35. Lee J., Zaki J., Harvey P.O., Ochsner K., Green M.F. Schizophrenia patients are impaired in empathic accuracy. Psychological Medicine 2011, 41(11):1-8.
36. Marder S.R., Fenton W. Measurement and treatment research to improve cognition in schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia. Schizophrenia Research 2004, 72(1):5-9.
37. Montgomery S.A., Asberg M. A new depression scale designed to be sensitive to change. British Journal of Psychiatry 1979, 134:382-389.
38. Morelli S.A., Rameson L.T., Lieberman M.D. The neural components of empathy: predicting daily prosocial behavior. Social and Cognitive Affective Neuroscience 2014, 9(1):39-47.
39. O[U+05F3]Connor L.E., Berry J.W., Weiss J., Gilbert P. Guilt, fear, submission, and empathy in depression. Journal of Affective Disorders 2002, 71(1-3):19-27.
40. Patterson T.L., Moscona S., McKibbin C.L., Davidson K., Jeste D.V. Social skills performance assessment among older patients with schizophrenia. Schizophrenia Research 2001, 48(2-3):351-360.
41. Preacher K.J., Hayes A.F. SPSS and SAS procedures for estimating indirect effects in simple mediation models. Behavior Research Methods, Instruments, & Computers: A Journal of the Psychonomic Society, Inc. 2004, 36(4):717-731.
42. Preston S.D., de Waal F.B. Empathy: its ultimate and proximate bases. Behavioral and Brain sciences 2002, 25(1):20-71. (1-20; discussion).
43. Reitan R., Wolfson D. The Halstead-Reitan Neuropsycholoigcal Test Battery: Theory and Clinical Interpretation 1985, Neuropsychology Press, Tucson, AZ.
44. Reniers R.L., Corcoran R., Drake R., Shryane N.M., Vollm B.A. The QCAE: a Questionnaire of Cognitive and Affective Empathy. Journal of Personality Assessments 2011, 93(1):84-95.
45. Ripoll L.H., Zaki J., Perez-Rodriguez M.M., Snyder R., Strike K.S., Boussi A., Bartz J.A., Ochsner K.N., Siever L.J., New A.S. Empathic accuracy and cognition in schizotypal personality disorder. Psychiatry Research 2013, 210:232-241.
46. Ritter K., Dziobek I., Preissler S., Rüter A., Vater A., Fydrich T., Lammers C.H., Heekeren H.R., Roepke S. Lack of empathy in patients with narcissistic personality disorder. Psychiatry Research 2011, 187:241-247.
47. Roepke S., Vater A., Preißler S., Heekeren H.R., Dziobek I. Social cognition in borderline personality disorder. Frontiers in Neuroscience 2012, 6:195.
48. Sax K.W., Strakowski S.M., Keck P.E., Upadhyaya V.H., West S.A., McElroy S.L. Relationships among negative, positive, and depressive symptoms in schizophrenia and psychotic depression. British Journal of Psychiatry 1996, 168(1):68-71.
49. Schneider L.C., Struening E.L. SLOF: a behavioral rating scale for assessing the mentally ill. Social Work Research Abstracts 1983, 19(3):9-21.
50. Schreiter S., Pijnenborg G.H., Aan He tRot M. Empathy in adults with clinical or subclinical depressive symptoms. Journal of Affective Disorders 2013, 150(1):1-16.
51. Shahar G., Weinberg D., McGlashan T.H., Davidson L. Illness related stress interacts with perception of the self as ill to predict depression in psychosis. International Journal Cognitive Therapy 2010, 3(2):202-210.
52. Shamay-Tsoory S.G. The neural bases for empathy. Neuroscientist 2011, 17(1):18-24.
53. Shamay-Tsoory S.G., Shur S., Harari H., Levkovitz Y. Neurocognitive basis of impaired empathy in schizophrenia. Neuropsychology 2007, 21(4):431-438.
54. Simonsen C., Sundet K., Vaskinn A., Ueland T., Romm K.L., Hellvin T., Melle I., Friis S., Andreassen O.A. Psychosocial function in schizophrenia and bipolar disorder: relationship to neurocognition and clinical symptoms. Journal of International Neuropsycholology Society 2010, 16(5):771-783.
55. Smith, M.J., Horan, W.P., Cobia, D.J., Karpouzian, T.M., Fox, J.M., Reilly, J.L., Breiter, H.C., 2013. Performance-based empathy mediates the influence of working memory on social competence in schizophrenia. Schizophrenia Bulletin, electronic publication 31 December; http://dx.doi.org/10.1093/schbul/sbt084.
56. Smith M.J., Horan W.P., Karpouzian T.M., Abram S.V., Cobia D.J., Csernansky J.G. Self-reported empathy deficits are uniquely associated with poor functioning in schizophrenia. Schizophrenia Research 2012, 137(1-3):196-202.
57. Sparks A., McDonald S., Lino B., O[U+05F3]Donnell M., Green M.J. Social cognition, empathy and functional outcome in schizophrenia. Schizophrenia Research 2010, 122(1-3):172-178.
58. Tabachnick B.G., Fidell L.S. Using multivariate statistics. Using Multivariate Statistics 2012, Allyn and Bacon, Boston. 6th ed. B.G. Tabachnick, L.S. Fidell (Eds.).
59. Thoma P., Zalewski I., von Reventlow H.G., Norra C., Juckel G., Daum I. Cognitive and affective empathy in depression linked to executive control. Psychiatry Research 2011, 189(3):373-378.
60. Tucker D.M., Luu P., Derryberry D. Love hurts: the evolution of empathic concern through the encephalization of nociceptive capacity. Development and Psychopathology 2005, 17(3):699-713.
61. Wechsler D. Wechsler Adult Intelligence Scale 1997, The Psychological Corporation, San Antonio. Third Edition.
62. Wechsler D. Wechsler Memory Scale 1997, The Psychological Corporation, San Antonio. Third Edition.
63. Zaki J., Bolger N., Ochsner K. It takes two: the interpersonal nature of empathic accuracy. Psychological Science 2008, 19(4):399-404.
64. Zaki J., Ochsner K. Reintegrating the study of accuracy into social cognition research. Psychological Inquiry 2011, 22(3):159-182.