A novel chitosan-γPGA polyelectrolyte complex hydrogel promotes early new bone formation in the alveolar socket following tooth extraction

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Chang, Hao Hueng ^a,b   Wang, Yin Lin ^a,b   Chiang, Yu Chih ^a,b   Chen, Yen Liang ^a,b   Chuang, Yu Horng ^a   Tsai, Shang Jye ^a,c   Heish, Kuo Huang ^a   Lin, Feng Huei ^a   Lin, Chun Pin ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c CARDINAL TIEN HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN; GELATIN SPONGE; POLYELECTROLYTE; CHITOSAN-POLY(GAMMA-GLUTAMIC ACID); POLYGLUTAMIC ACID;

ALVEOLAR BONE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; HYDROGEL; INCISOR; MALE; MORPHOMETRICS; NONHUMAN; OSSIFICATION; RADIOGRAPHY; RAT; TOOTH EXTRACTION; TOOTH SOCKET; ANALOGS AND DERIVATIVES; ANIMAL; BONE DEVELOPMENT; DRUG EFFECTS; JAW; PATHOLOGY; WISTAR RAT; WOUND HEALING;

ALVEOLAR PROCESS; ANIMALS; CHITOSAN; MALE; OSTEOGENESIS; POLYGLUTAMIC ACID; RATS, WISTAR; TOOTH EXTRACTION; WOUND HEALING;

EID: 84899064935     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092362     Document Type: Article

References (33)

1. Vignoletti F, Matesanz P, Rodrigo D, Figuero E, Martin C, et al. (2012) Surgical protocols for ridge preservation after tooth extraction. A systematic review. Clin Oral Implants Res 23 Suppl 5: 22-38.
2. Klokkevold PR, Vandemark L, Kenney EB, Bernard GW (1996) Osteogenesis enhanced by chitosan (poly-N-acetyl glucosaminoglycan) in vitro. J Periodontol 67: 1170-1175. (Pubitemid 26413008)
3. Gauthier O, Boix D, Grimandi G, Aguado E, Bouler JM, et al. (1999) A new injectable calcium phosphate biomaterial for immediate bone filling of extraction sockets: a preliminary study in dogs. J Periodontol 70: 375-383.
4. Liu H, Peng H, Wu Y, Zhang C, Cai Y, et al. (2013) The promotion of bone regeneration by nanofibrous hydroxyapatite/chitosan scaffolds by effects on integrin-BMP/Smad signaling pathway in BMSCs. Biomaterials 34: 4404-4417.
5. Khanna R, Katti KS, Katti DR (2011) Bone nodules on chitosan- polygalacturonic acid-hydroxyapatite nanocomposite films mimic hierarchy of natural bone. Acta Biomater 7: 1173-1183.
6. Roriz VM, Rosa AL, Peitl O, Zanotto ED, Panzeri H, et al. (2010) Efficacy of a bioactive glass-ceramic (Biosilicate) in the maintenance of alveolar ridges and in osseointegration of titanium implants. Clin Oral Implants Res 21: 148-155.
7. Ezoddini-Ardakani F, Navabazam A, Fatehi F, Danesh-Ardekani M, Khadem S, et al. (2012) Histologic evaluation of chitosan as an accelerator of bone regeneration in microdrilled rat tibias. Dent Res J (Isfahan) 9: 694-699.
8. Oka S, Matsumoto T, Kubo S, Matsushita T, Sasaki H, et al. (2013) Local administration of low-dose simvastatin-conjugated gelatin hydrogel for tendon-bone healing in anterior cruciate ligament reconstruction. Tissue Eng Part A 19: 1233-1243.
9. Li M, Liu X, Ge B (2010) Calcium phosphate cement with BMP-2-loaded gelatin microspheres enhances bone healing in osteoporosis: a pilot study. Clin Orthop Relat Res 468: 1978-1985.
10. Miranda SC, Silva GA, Hell RC, Martins MD, Alves JB, et al. (2011) Three-dimensional culture of rat BMMSCs in a porous chitosan-gelatin scaffold: A promising association for bone tissue engineering in oral reconstruction. Arch Oral Biol 56: 1-15.
11. Tsao CT, Chang CH, Lin YY, Wu MF, Wang JL, et al. (2010) Antibacterial activity and biocompatibility of a chitosan-gamma-poly(glutamic acid) polyelectrolyte complex hydrogel. Carbohydr Res 345: 1774-1780.
12. Tsao CT, Chang CH, Lin YY, Wu MF, Wang JL, et al. (2011) Evaluation of chitosan/c-poly(glutamic acid) polyelectrolyte complex for wound dressing materials. Carbohydr Polym 84: 812-819.
13. Tsao CT, Chang CH, Lin YY, Wu MF, Han JL, et al. (2011) Kinetic study of acid depolymerization of chitosan and effects of low molecular weight chitosan on erythrocyte rouleaux formation. Carbohydr Res 346: 94-102.
14. Badawy MEI, Rabea EI (2011) A Biopolymer Chitosan and Its Derivatives as Promising Antimicrobial Agents against Plant Pathogens and Their Applications in Crop Protection. International Journal of Carbohydrate Chemistry 2011. doi:10.1155/2011/460381
15. Tsuchida E (1994) Formation of Polyelectrolyte Complexes and Their Structures. Journal of Macromolecular Science, Part A 31: 1-15.
16. Boyan BD, Ranly DM, McMillan J, Sunwoo M, Roche K, et al. (2006) Osteoinductive ability of human allograft formulations. J Periodontol 77: 1555-1563. (Pubitemid 44740766)
17. Berglundh T, Abrahamsson I, Lang NP, Lindhe J (2003) De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res 14: 251-262. (Pubitemid 37465524)
18. Donath K, Breuner G (1982) A method for the study of undecalcified bones and teeth with attached soft tissues. The Sage-Schliff (sawing and grinding) technique. J Oral Pathol 11: 318-326. (Pubitemid 12092572)
19. Schroeder HE, Munzel-Pedrazzoli S (1973) Correlated morphometric and biochemical analysis of gingival tissue. Morphometric model, tissue sampling and test of stereologic procedures. J Microsc 99: 301-329.
20. Abrahamsson I, Berglundh T, Linder E, Lang NP, Lindhe J (2004) Early bone formation adjacent to rough and turned endosseous implant surfaces. An experimental study in the dog. Clin Oral Implants Res 15: 381-392. (Pubitemid 40115764)
21. Araujo MG, Lindhe J (2009) Ridge preservation with the use of Bio-Oss collagen: A 6-month study in the dog. Clin Oral Implants Res 20: 433-440.
22. Arruda T, Sukekava F, de Souza AB, Rasmusson L, Araujo MG (2012) Early healing in alveolar sockets grafted with titanium granules. An experimental study in a dog model. J Biomed Mater Res A. 101: 1971-1976.
23. Santos FA, Pochapski MT, Martins MC, Zenobio EG, Spolidoro LC, et al. (2010) Comparison of biomaterial implants in the dental socket: histological analysis in dogs. Clin Implant Dent Relat Res 12: 18-25.
24. Bumgardner JD, Wiser R, Gerard PD, Bergin P, Chestnutt B, et al. (2003) Chitosan: potential use as a bioactive coating for orthopaedic and craniofacial/dental implants. J Biomater Sci Polym Ed 14: 423-438. (Pubitemid 36681493)
25. Bumgardner JD, Wiser R, Elder SH, Jouett R, Yang Y, et al. (2003) Contact angle, protein adsorption and osteoblast precursor cell attachment to chitosan coatings bonded to titanium. J Biomater Sci Polym Ed 14: 1401-1409. (Pubitemid 38028752)
26. Muzzarelli RA (1999) Clinical and biochemical evaluation of chitosan for hypercholesterolemia and overweight control. EXS 87: 293-304.
27. Muzzarelli RA, Mattioli-Belmonte M, Pugnaloni A, Biagini G (1999) Biochemistry, histology and clinical uses of chitins and chitosans in wound healing. EXS 87: 251-264.
28. Muzzarelli RA (1999) Analytical biochemistry and clinical significance of N-acetyl-beta-D-glucosaminidase and related enzymes. EXS 87: 235-247.
29. Muzzarelli RA, Mattioli-Belmonte M, Tietz C, Biagini R, Ferioli G, et al. (1994) Stimulatory effect on bone formation exerted by a modified chitosan. Biomaterials 15: 1075-1081. (Pubitemid 24345934)
30. Shokrgozar MA, Fattahi M, Bonakdar S, Ragerdi Kashani I, Majidi M, et al. (2012) Healing potential of mesenchymal stem cells cultured on a collagen-based scaffold for skin regeneration. Iran Biomed J 16: 68-76.
31. Kim IY, Seo SJ, Moon HS, Yoo MK, Park IY, et al. (2008) Chitosan and its derivatives for tissue engineering applications. Biotechnol Adv 26: 1-21.
32. Hsieh CY, Tsai SP, Wang DM, Chang YN, Hsieh HJ (2005) Preparation of gamma-PGA/chitosan composite tissue engineering matrices. Biomaterials 26: 5617-5623.
33. Hsieh CY, Hsieh HJ, Liu HC, Wang DM, Hou LT (2006) Fabrication and release behavior of a novel freeze-gelled chitosan/gamma-PGA scaffold as a carrier for rhBMP-2. Dent Mater 22: 622-629.